Ann Cowan, Ph.D.

Professor, Department of Molecular Biology and Biophysics
Deputy Director, Center for Cell Analysis and Modeling
Academic Office Location:
Molecular Biology and Biophysics
University of Connecticut Health Center
263 Farmington Avenue
Farmington, CT 06030-6406
Phone: 860-679-1449
Fax: 860-679-1039
Email: acowan@nso2.uchc.edu
Website(s): Cell Biology Graduate Program
Cell Analysis and Modeling Graduate Program
Moelcular Biology & Biochemistry Graduate Program

Education
DegreeInstitutionMajor
Ph.D.University of ColoradoMolecular, Cellular, and Developmental Biology
M.S.Yale University Biology
B.S.Queen’s UniversityBiology

Post-Graduate Training
TrainingInstitutionSpecialty
Professional TrainingNIHNational Institutes of Health Predoctoral Traineeship
FellowshipLalor FoundationPostdoctoral Fellowship
PostdoctoralDamon Runyon-Walter Winchell Cancer Fund
PostdoctoralUniversity of Connecticut Health CenterDepartment of Physiology

Awards
Name of Award/HonorAwarding Organization
Osborn Biomedical Science Graduate Teaching Award Recipient Graduate Student Organization
Postdoctoral FellowshipLalor Foundation
Postdoctoral Fellowship 1984-1987Damon Runyon-Walter Winchell Cancer Fund
B. Sc. (Honours) with First Class HonoursQueen’s University
Predoctoral Traineeship 1977-1980National Institute of Health
My general research interests center on the dynamic organization of the plasma membrane and in the application of quantitative fluorescence imaging and biophysical methods to the study of molecular events in living cells. The Richard D. Berlin Center for Cell Analysis and Modeling (CCAM) is a highly collaborative research center that integrates optical engineering, biophysics, and computational methods to study cell biological mechanisms. As part of an interdisciplinary team at CCAM's NIH-funded National Resource for Cell analysis and Modeling (NRCAM), I combine high resolution quantitative imaging and biochemical analyses with mathematical modeling to develop computational simulations of specific cellular events. NRCAM is home to the “Virtual Cell” (VCell) modeling environment, a tool for creating spatially realistic mathematical models of cellular processes using a web-based interface that is freely available to the academic research community. I am currently focused on developing a suite of dedicating software utilizing VCell simulation technology to analyze quantitative imaging applications such as fluorescence redistribution after photobleaching (FRAP), FRET-based fluroescence biosensor measurements and optogenetics. As Director of the CCAM Microscopy User Facility, I oversee a facility of confocal, 2-photon, FCS and TIRF microscopes that provides advanced imaging capabilities to the UCHC and broader research community. I also collaborate extensively in projects that apply quantitative fluorescence imaging to a wide range of cellular systems.

Not accepting students for Lab Rotations at this time

Journal Articles

Conference Papers

Title or AbstractTypeSponsor/EventDate/YearLocation
Talk UnknownTalkNational Technology Centers for Networks and Pathways All Hands Meeting2007Bethesda, MD
Booth at 2006 Annual Meeting Society for the Advancement of Chicano and Native American Scientists for student recruitmentOther2006 Annual Meeting Society for the Advancement of Chicano and Native American Scientists 2006
Title UnknownTalkHoward University Workshop on Computational Cell Biology2005Washington, CT
Title UnknownTalkNortheast Spore Meetings,2002Harvard University, Cambridge, MA
Title UnknownTalkCenter for Microbial Pathogenesis, UCHC2002
Title Unknown (cancelled due to 9/11 events)TalkIowa Microscopy Society Meeting, University of Iowa2001 Ames, IO
Confocal Demonstration and Tour for Avon High School studentsOtherUConn Health Center2001Farmington, CT
Confocal Demonstration and Tour, UConn Clinical Engineering studentsOtherUConn Health Center2000Farmington, CT
Confocal Microscopy Demonstration for students in Biological Structure Course at Wesleyan UniversityOtherUConn Health Center1999Middletown, CT
Title UnknownTalkSociety for the Study of Reproduction Annual Meeting1998College Station, TX
Title UnknownTalkThe Population Council, Center for Biomedical Research1997New York, NY
Photonics: Teaching Across the SpectrumTalkConference for Science and Technology Teachers, University of Connecticut1997Storrs, CT
Confocal Demonstration and Tour, Science Teacher Onsite VisitOtherMiddletown High School1997Middletown, CT
CPTV’s Family Science ExpoOtherCT Public TV1997Hartford, CT
Targets for Contraceptive DevelopmentTalkNICHD workshop, NIH1994Bethesda, MD
Title UnknownTalkLoeb Institute, Civic Hospital, 1993Ottawa, Ontario, Canada
Title UnknownTalkDepartment of Anatomy and Cell Biology. University of Alberta1992Calgary, Alberta, Canada
Title UnknownTalkDepartment of Obstetrics and Gynecology, Tufts University School of Medicine1992Boston, MA
title UnknownTalkDepartment of Anatomy, University of Arizona Health Sciences Center1991Tuscon, AR
Fertilization and Activation of DevelopmentTalkGordon Conference1991NH
Title UnknownTalkDepartment of Biological Sciences, SUNY at Buffalo1990Buffalo, NY
Title UnknownTalkDivision of Reproductive Biology, University of Pennsylvania Medical Center 1989PA