Photo of Jeremy R. Egbert, Ph.D.

Jeremy R. Egbert, Ph.D.

Assistant Professor, Department of Cell Biology
Academic Office Location:
Cell Biology, E-6029
UConn Health
263 Farmington Avenue
Farmington, CT 06030-3636
Phone: 860-679-2677
Email: EGBERT@uchc.edu

Dr. Egbert joined the UConn Health faculty in 2016 after postdoctoral training in the lab of Prof. Laurinda Jaffe at UConn Health. As a postdoc, Dr. Egbert studied the mechanisms by which luteinizing hormone (LH) signaling rapidly reduces cGMP levels in the granulosa cells of ovarian follicles. The decrease in cGMP levels causes the oocyte to resume meiosis, which is required for the oocyte to be fertilized. Dr. Egbert is currently using novel mice that express different calcium sensors and confocal microscopy to study the mechanisms and functions of calcium increases within granulosa cells in response to the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Dr. Egbert received his PhD in 2011 from Washington State University, working in the lab of Prof. Hubert Schwabl to study the sources of variation in the levels of avian yolk steroids, which impact offspring health and behavior.

Education
DegreeInstitutionMajor
B.S.Boise State UniversityBiology
M.S.Washington State UniversityZoology
Ph.D.Washington State UniversityZoology

Post-Graduate Training
TrainingInstitutionSpecialty
Scientific TrainingMarine Biological LaboratoryAttended Frontiers in Reproduction, a 6-week scientific training course May — June 2011.

Awards
Name of Award/HonorAwarding Organization
Trainee Travel Fund Award, SSR annual meeting.Larry Ewing Memorial
Brislawn Graduate FellowshipWSU
Abelson Science Scholarship (3 years)WSU
2003 Best Poster AwardCooper Ornithological Society meeting, Flagstaff, AZ
Associate Member, Sigma XiThe Scientific Research Society, BSU Chapter
Top Ten Scholars Award, 2002 — 2003 academic year.Boise State University
Scholarship, BSU (4 years)Laura Moore Cunningham Foundation
Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
Society for the Study of Reproduction (2018 — present).Professional/Scientific OrganizationRegular MemberNational2018
Society for the Study of Reproduction (2017-2019).Professional/Scientific OrganizationDevelopment Committee Trainee MemberExternalNational20172019
Graduate Student Research Day, UConn HealthEducation CommitteePoster Competition JudgeUniversity20142015
Society for the Study of ReproductionProfessional/Scientific OrganizationNominating Committee Trainee MemberExternalNational20142015
Society for the Study of ReproductionProfessional/Scientific OrganizationTrainee MemberExternalNational20132017
Professional Activities Coordinator for the Society for the Study of Reproduction 2018 Trainee-Mentor Luncheon.Education CommitteeExternalNational2018
Biology of Reproduction, Journal of Ovarian Research, Molecular Reproduction and Development, Developmental Biology.Professional/Scientific JournalAd Hoc reviewerExternalNational

Journal Articles

Title or AbstractTypeSponsor/EventDate/YearLocation
Calcium dynamics in intact ovarian folliclesPosterSociety for the Study of Reproduction meeting2018New Orleans, LA
Long distance regulation of mammalian oocyte meiosis by luteinizing hormone signaling.TalkUndergraduate Cell Biology course (MCB 2210),2017UConn, Waterbury
LH signaling in mouse ovarian follicles rapidly elevates calcium, thus activating the cGMP phosphodiesterase PDE1A and contributing to the cGMP decrease that restarts oocyte meiosisPosterSociety for the Study of Reproduction meeting2017Washington, D.C.
Luteinizing hormone signaling shifts the balance between synthesis and hydrolysis of cyclic GMP in rat ovarian follicles, leading to meiotic resumptionTalkFrontiers in Reproduction Symposium2016Woods Hole, MA
Phosphorylation of the cGMP phosphodiesterase PDE5 is required for the LH-induced increase in cGMP hydrolytic activity in mouse ovarian folliclesPosterSociety for the Study of Reproduction meeting2016San Diego, CA
Luteinizing hormone signaling rapidly reduces cyclic GMP levels in rat ovarian follicles by dephosphorylation of NPR2 and phosphorylation of PDE5A, leading to meiotic resumptionTalkSociety for the Study of Reproduction meeting2015San Juan, Puerto Rico
Luteinizing hormone signaling decreases cyclic GMP production in rat ovarian follicles by rapidly dephosphorylating the NPR2 guanylyl cyclase through a PPP-family phosphatasePosterSociety for Developmental Biology, New England regional meeting2014Woods Hole, MA
Luteinizing hormone signaling initiates rapid dephosphorylation of the NPR2 guanylyl cyclase, causing a progressive decline in cyclic GMP in mammalian granulosa cells and oocytesPosterSociety for the Study of Reproduction meeting2013Montreal, Quebec, Canada
Luteinizing hormone signaling decreases cyclic GMP production in rat ovarian follicles by rapidly dephosphorylating the NPR2 guanylyl cyclase and by slowly decreasing its agonist CNPPosterOocyte Maturation and Fertilization meeting2013Banyuls-Sur-Mer, France
Effect of tamoxifen on yolk steroid levels in house sparrows: toward a mechanism of yolk steroid accumulationTalkAmerican Ornithologist’s Union meeting2009Philadelphia, PA
A novel experimental test of the relationship between plasma and yolk testosterone levels in the house sparrow (Passer domesticus)TalkSociety for Integrative and Comparative Biology meeting2007Phoenix, AZ
Behavioral and endocrine responses of female house sparrows to a social challenge: the relationship between plasma and yolk testosteronePosterNorth American Ornithological Congress2006Veracruz, Mexico
Wing shape in house finches differs relative to migratory habit in eastern and western North AmericaPosterCooper Ornithological Society meeting2003Flagstaff, AZ