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BosR and PlzA reciprocally regulate RpoS function to sustain Borrelia burgdorferi in ticks and mammals.
Grassmann, André A; Tokarz, Rafal; Golino, Caroline; McLain, Melissa A; Groshong, Ashley M; Radolf, Justin D; Caimano, Melissa J The Journal of clinical investigation 2023 Jan;
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PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi.
Groshong, Ashley M; Grassmann, André A; Luthra, Amit; McLain, Melissa A; Provatas, Anthony A; Radolf, Justin D; Caimano, Melissa J PLoS pathogens 2021 Jul;17(7):e1009725
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Host-specific functional compartmentalization within the oligopeptide transporter during the Borrelia burgdorferi enzootic cycle.
Groshong, Ashley M; McLain, Melissa A; Radolf, Justin D PLoS pathogens 2021 Jan;17(1):e1009180
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The BB0345 hypothetical protein of Borrelia burgdorferi is essential for mammalian infection.
Graham, Danielle E; Groshong, Ashley M; Jackson-Litteken, Clay D; Moore, Brendan P; Caimano, Melissa J; Blevins, Jon S Infection and immunity 2020 Sep;
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The RpoS Gatekeeper in Borrelia burgdorferi: An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity.
Caimano, Melissa J; Groshong, Ashley M; Belperron, Alexia; Mao, Jialing; Hawley, Kelly L; Luthra, Amit; Graham, Danielle E; Earnhart, Christopher G; Marconi, Richard T; Bockenstedt, Linda K; Blevins, Jon S; Radolf, Justin D Frontiers in microbiology 2019 Sep;101923
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DksA controls the response of the Lyme disease spirochete Borrelia burgdorferi to starvation.
Boyle, William K; Groshong, Ashley M; Drecktrah, Dan; Boylan, Julie A; Gherardini, Frank C; Blevins, Jon S; Samuels, D Scott; Bourret, Travis J Journal of bacteriology 2018 Nov;
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Peptide Uptake Is Essential for Borrelia burgdorferi Viability and Involves Structural and Regulatory Complexity of its Oligopeptide Transporter.
Groshong, Ashley M; Dey, Abhishek; Bezsonova, Irina; Caimano, Melissa J; Radolf, Justin D mBio 2017 Dec;8(6):
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BB0744 Affects Tissue Tropism and Spatial Distribution of Borrelia burgdorferi.
Wager, Beau; Shaw, Dana K; Groshong, Ashley M; Blevins, Jon S; Skare, Jon T Infection and immunity 2015 Sep;83(9):3693-703
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BB0238, a presumed tetratricopeptide repeat-containing protein, is required during Borrelia burgdorferi mammalian infection.
Groshong, Ashley M; Fortune, Danielle E; Moore, Brendan P; Spencer, Horace J; Skinner, Robert A; Bellamy, William T; Blevins, Jon S Infection and immunity 2014 Oct;82(10):4292-306
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Identification of lysine residues in the Borrelia burgdorferi DbpA adhesin required for murine infection.
Fortune, Danielle E; Lin, Yi-Pin; Deka, Ranjit K; Groshong, Ashley M; Moore, Brendan P; Hagman, Kayla E; Leong, John M; Tomchick, Diana R; Blevins, Jon S Infection and immunity 2014 Aug;82(8):3186-98
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Insights into the biology of Borrelia burgdorferi gained through the application of molecular genetics.
Groshong, Ashley M; Blevins, Jon S Advances in applied microbiology 2014 Jan;8641-143
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Neutralization of B. anthracis toxins during ex vivo phagocytosis.
Tarasenko, Olga; Scott, Ashley; Jones, April; Soderberg, Lee; Alusta, Pierre Glycoconjugate journal 2013 Jul;30(5):473-84
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Rrp2, a prokaryotic enhancer-like binding protein, is essential for viability of Borrelia burgdorferi.
Groshong, Ashley M; Gibbons, Nora E; Yang, X Frank; Blevins, Jon S Journal of bacteriology 2012 Jul;194(13):3336-42
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Glycoconjugates prevent B. anthracis toxin-induced cell death through binding while activating macrophages.
Tarasenko, Olga; Scott, Ashley; Soderberg, Lee; Alusta, Pierre Glycoconjugate journal 2012 Jan;29(1):25-33
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Killing of Bacillus spores is mediated by nitric oxide and nitric oxide synthase during glycoconjugate-enhanced phagocytosis.
Tarasenko, Olga; Scott, Ashley; Soderberg, Lee; Ponnappan, Usha; Alusta, Pierre Glycoconjugate journal 2010 Jan;27(1):13-25