Upendra P. Hegde, M.D.

Assistant Professor, Department of Medicine
Academic Office Location:
Medicine
University of Connecticut Health Center
263 Farmington Avenue
Farmington, CT 06030
Phone: 800-579-7822
860-679-2100

Education
DegreeInstitutionMajor
M.D.Goa Medical CollegeGeneral Medicine
M.B.B.S.Goa Medical CollegeMedicine, Surgery

Post-Graduate Training
TrainingInstitutionSpecialty
ResidencyGoa Medical College and HospitalCompulsory Rotatory
ResidencyGoa Medical College and HospitalPsychiatry and Human Behavior
ResidencyGoa Medical College and HospitalInternal Medicine
ResidencyGoa Medical College and HospitalInternal Medicine
FellowshipTata Memorial Cancer HospitalHematology/Oncology
FellowshipTata Memorial HospitalHematology/Oncology
OtherRush University Cancer Institute
ResidencyCook County HospitalInternal Medicine
FellowshipNational Heart, Lung and Blood InstituteHematology and Medical Oncology

Awards
Name of Award/HonorAwarding Organization
America’s Best DoctorUS Public News
Named Top Doctor, Connecticut Magazine Survey of Connecticut Doctors Connecticut Magazine
Best Teaching Award, Hematology/Oncology Training Program, 2008-2009 UConn Health Center
PAWS Team Award, UConn Health CenterUConn Health Center Cares Council
Recipient of scholarship towards ASCO/AACR Workshop
Humanitarian Resident AwardCook County Hospital
Humanitarian Resident Award, Chicago, Illinois, 1996-1997 Cook County Hospital
USMLE 1, 2, 3
J.N. Tata Endowment Travel Scholarship
Research Scholarship, Chicago, Illinois, 1992-1995 Rush University Cancer Institute
Khandelwal Junior Oncology Award, Madras, India Indian Society of Oncology
Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
Cancer Immunity JournalProfessional/Scientific JournalReviewerExternalNational2013
Institutional Review BoardProfessional/Scientific OrganizationVice ChairUConn Health CenterUniversity2013
International Society of Geriatric OncologyProfessional/Scientific OrganizationMemberExternalInternational20092011
Schwartz Round Planning and Patient Selection CommitteeProfessional/Scientific OrganizationMemberUConn Health CenterUniversity2009
Scientific Review Committee for the American Cancer Society Research Awards Professional/Scientific OrganizationCommittee MemberExternalNational2009
Scientific Review Committee for the Institutional American Cancer Society Research AwardProfessional/Scientific OrganizationMemberUConn Health CenterUniversity2009
Search Committee for Faculty RecruitmentEducation CommitteeCommittee MemberUConn Health CenterUniversity2009
Search Committee for Gynecologic Oncology Faculty RecruitmentProfessional/Scientific OrganizationQuality Assurance LiaisonUConn Health CenterUniversity2009
Search Committee for Medical Oncology/Hematology Faculty RecruitmentProfessional/Scientific OrganizationMemberUConn Health CenterUniversity2009
Journal of Gerontology: Medical SciencesAdvisory CommitteeReviewerExternalNational2008
Journal of Gerontology: Medical SciencesProfessional/Scientific JournalAdhoc reviewerExternalNational2008
Institutional Review BoardProfessional/Scientific OrganizationMemberUConn Health CenterUniversity20062012
Institutional Review Board Advisory CommitteeReviewerExternalUniversity2006
American Association for Cancer ResearchProfessional/Scientific OrganizationMemberExternalNational2005
Research Adverse Event CommitteeProfessional/Scientific OrganizationMemberUConn Health CenterUniversity20042006
Research Adverse Events CommitteeResearch CommitteeCommittee MemberExternalUniversity20042006
Cancer Registry and Quality Control CommitteeProfessional/Scientific OrganizationMemberUConn Health CenterUniversity2003
Connecticut State Society of Medical OncologyProfessional/Scientific OrganizationMemberExternalState2003
Pastoral CommitteeProfessional/Scientific OrganizationCommittee MemberExternalUniversity20032007
Pastoral CommitteeProfessional/Scientific OrganizationMemberUConn Health CenterUniversity20032007
Hartford County Medical AssociationProfessional/Scientific OrganizationMemberExternalLocal2002
ASCO/AACR Workshop Participant and PresentorProfessional/Scientific OrganizationParticipantExternalNational2001
American Society of Clinical OncologyProfessional/Scientific OrganizationMemberExternalNational2000
American Society of HematologyProfessional/Scientific OrganizationMemberExternalNational19982003
Department of Medicine Q/A committeeProfessional/Scientific OrganizationLiaisonUConn Health CenterUniversity

Journal Articles

Book Chapters

  • Biliary Tract Cancers
    Hegde, U., Grem, J. Bethesda Manual of Clinical Oncology
  • New Treatment Strategies in Chronic Lymphocytic Leukemia
    Hegde, U. and Wilson, W.H. Chronic Lymphocytic Leukemia: Molecular Genetics, Biology, Diagnosis, and Management
  • Primary Cancers of the Liver
    Hegde, U., Grem, J. Bethesda Manual of Clinical Oncology
  • Skin Cancers and Melanoma
    Hegde, U., Agarwala, S. Bethesda Manual of Clinical Oncology
  • Skin Cancers and Melanoma
    Hegde, U., Barry Gause Bethesda Manual of Clinical Oncology
  • Skin Cancers and Melanoma
    Hegde, U., Gause, B. Bethesda Manual of Clinical Oncology
  • Skin Cancers and Melanoma
    Hegde, U., Legha, S.S. Bethesda Manual of Clinical Oncology

Abstracts

  • Analyses of the Immunologically Relevant Gene Transcript by qRT-PCR in Primary Cutaneous Melanoma by the Young and the Elderly
    Hegde, U.P., Dadras, S., Chakraborty, N., Kerr, P., Grant Kels, J., Mukherji, B. American Society of Clinical Oncology Electronic Publication

Case Reports

  • Chronic Myeloid Leukemia Following Radioactive Iodine I131 Therapy of Thyroid Cancer; A Case Report with Review of Literature
    Hegde, U.P., Gopal, R., Nanjangoud, G., Advani, S.H. Leuk Lymphoma 5215-217

Newsletters

  • Heat shock protein vaccine show promise against metastatic melanoma
    Li, Z., Laska, E., Hegde, U. UCONN Cancer Dialogue 21-2

Reviews

Title or AbstractTypeSponsor/EventDate/YearLocation
Comparison of T Cell Responses to a Melanoma -Related Antigen in Elderly and Young PatientsPosterAmerican Association of Cancer Research2013Washington D.C.
Highlighting Melanoma Treatment – Discovery SeriesTalkUniversity of Connecticut Health Center2013Farmington, Connecticut
Challenges in the Delivery of Newer Treatment of Metastatic MelanomaTalkUniversity of Connecticut2013Farmington, Connecticut
New Treatment of Metastatic MelanomaTalkUniversity of Connecticut Health Center2012Farmington, Connecticut
Treatment of Metastatic Melanoma: Hope and ChallengesTalkUniversity of Connecticut Health Center2012Farmington, Connecticut
Ageing and Melanoma: Relevance of the Ageing Immune System – Aging InstituteTalkUniversity of Connecticut Health Center2012Farmington, Connecticut
Sequential Treatment of Locally Advanced Squamous Cell Carcinoma of the Oropharynx (LASCCO) Using Docetaxel, Platinum and Fluorouracil (TPF) Induction Regimen: Retrospective Results from a Single InstitutionTalkAmerican Society of Clinical Oncology2011Chicago, Illinois
Induction Chemotherapy of Locally Advanced Nasopharyngeal Cancer with DPF Regimen Followed by Chemoradiation TherapyTalkAmerican Society of Clinical Oncology2011Chicago, Illinois
Massively Parallel Sequencing of Formalin-Embedded TissuePosterAmerican Association of Cancer Research2011Orlando, Florida
Understanding the Molecular Basis of Disease and Targeted Drug Therapy: Tuberous Sclerosis RevisitedTalkNew England Society of General Internal Medicine2011
A Comprehensive Analysis of the T Cell-Mediated Adaptive Immune Function in the Elderly Melanoma Patients Using Engineered Mart-1 Specific T Cell Receptor (TCR)PosterAmerican Association of Cancer Research2011Orlando, Florida
Newer Treatment of Metastatic MelanomaTalkUniversity of Connecticut Health Center2011Farmington, Connecticut
Immune System and Brain and Body ConnectionsTalkInternational Ayurveda Conference2011Farmington, Connecticut
Treatment Outcomes of Metastatic Melanoma in the Elderly Patients: A Retrospective AnalysisTalkAmerican Society of Clinical Oncology2010Chicago, Illinois
Case report: Malignant Pleural MesotheliomaTalkAmerican College Of Physician2010
Insights into Ageing Immune System and its Relevance in Patients with Metastatic MelanomaTalkUniversity of Connecticut Health Center2010Farmington, Connecticut
Harnessing Immune System in the Treatment of Cutaneous MelanomaTalkUniversity of Connecticut School of Medicine2010Farmington, Connecticut
Functional Differences Between Induced T Reg Cells from Tumor Antigen Specific CTL Induction and Influenza Matrix Antigen Specific CTL Induction CulturesPosterAmerican Association of Cancer Research2009Denver, Colorado
Metastatic Melanoma in the Elderly: Case Series of Clinical Outcome and Immune Characteristics CorrelationTalkASCO Meeting2009
Metastatic Melanoma in the Elderly Population: Correlation of Clinical Outcome and Immune CharacteristicsPosterInternational Society of Geriatric Oncology2009Berlin, Germany
Functional Differences Between Induced T Regulatory Cells from Tumor Antigen Specific CTL Induction and Influenza Matrix Antigen Specific CTL Induction CulturesPosterAmerican Association for Cancer Research2009Denver, Colorado
Melanoma in the Elderly: Relevance of the Aging Immune SystemTalkNeag Cancer Center Research Retreat2009Farmington, Connecticut
Treating Melanoma in the Young and Elderly: Challenges and Immunologic InsightsTalkUniversity of Connecticut Health Center2009Farmington, Connecticut
Tyrosine Kinase Inhibitors: New Treatment Option for CancerTalkUniversity of Connecticut School of Medicine2009Farmington, Connecticut
Swallowing Function Following Radiotherapy or Chemo Radiotherapy for Advanced Stage Head and Neck CancerTalkInternational Conference on Head and Neck Cancer2008
Lack of Effective T Regulatory Cells and Advantage Over Melanoma Tumor for Elderly PatientsTalkAACR Meeting2008
Lack of Effective T Regulatory Cells and Advantage Over Melanoma Tumor for Elderly PatientsPosterAmerican Association for Cancer Research2008San Diego, California
Principles of Staging and New Treatment Approaches in the Treatment of Cutaneous MelanomaTalkUniversity of Connecticut Health Center2008Farmington, Connecticut
Th1 Conditions are Necessary for Longer Lasting Tumor Specific CTL Activity; Cyclophosphamide/Fludarabine Could Play Important Role by Blocking TregsTalkAACR Meeting2007
Th1 Conditions are Necessary for Longer Lasting Tumor Specific CTL Activity; Cyclophosphamide/Fludarabine Could Play Important Role by Blocking T RegsPosterAmerican Association for Cancer Research2007Los Angeles, California
New Approaches in the Treatment of Thyroid Cancer. Intercity Grand Round PresentationTalkUniversity of Connecticut Health Center2007Farmington, Connecticut
Frailty and its Relevance in Treatment Outcomes in Cancer PatientsTalkUniversity of Connecticut Health Center2007Farmington, Connecticut
Ex Vivo Expanded Human Cytolytic T Lymphocytes (CTL) that Acquire Effector Memory Phenotype are Preferentially Sensitive to Activation Induced Cell Death (AICD): Implications in ImmunologyTalkInternational Society for Biological Therapy of Cancer Meeting2006
New Use of Old Drugs in Cancer TreatmentTalkUniversity of Connecticut School of Medicine2006Farmington, Connecticut
Insular Thyroid Cancer: Molecular Biology and TreatmentTalkNew England Thyroid Association Annual Meeting2006Waltham, Massachusetts
Skin Cancer PreventionTalkUniversity of Connecticut Health Center2006Farmington, Connecticut
Malignant Melanoma: Principles of Treatment and ChallengesTalkUniversity of Connecticut Health Center2006Farmington, Connecticut
Increased Incidence of Cardiac Toxicity after Infusional 5-Fluorouracil, Cisplatin and Docetaxel Combination Chemotherapy in Patients with Locally Advanced Head and Neck CancerTalkASCO Meeting2005
Radiofrequency Ablation of LymphomaTalkASCO Meeting2005
Effects of T Regulatory Cells on Activation and Expansion of Tumor Epitope Specific CTL In VitroTalkAACR Meeting2005
Approaches to the Management of Older Cancer PatientsTalkUniversity Of Connecticut School of Medicine2005Farmington, Connecticut
Metastatic Melanoma in the Older PatientTalkNeag Cancer Center Research Retreat2004Farmington, Connecticut
Approach to a Patient with LeucopeniaTalkUniversity of Connecticut School of Medicine2004Farmington, Connecticut
Cancer in the ElderlyTalkManchester Memorial Hospital2004Manchester, Connecticut
Cancer in the Elderly: Challenges and RewardsTalkUniversity of Connecticut Health Center2004Farmington, Connecticut
Immunotherapeutic Approaches in Lymphoma TreatmentTalkUniversity of Connecticut, School of Medicine2003Farmington, Connecticut
Biology and Treatment Principles of Non Hodgkin’s LymphomaTalkRockville General Hospital2003Vernon, Connecticut
Phase I Study of Combination Rituximab (CD20) and Apolizumab (Hu1D10) Monoclonal Antibody Therapy in Previously Treated B-Cell LymphomaPosterAmerican Society of Hematology2002Philadelphia, Pennsylvania
High Incidence of Occult Leptomeningeal Disease Detected by Flow Cytometry in at Risk Newly Diagnosed B-Cell LymphomasTalkASH Meeting2001
Rituximab for the Treatment of Fludarabine (FAMP) Associated Autoimmune Thrombocytopenia in Chronic Lymphocytic Leukemia (CLL): Report of Three Cases from a Single InstitutionTalkASCO Meeting2001
Central Nervous System Radiological Abnormalities In Lymphomatoid GranulomatosisTalkRSNA Meeting2001
Incidence and Clinical Significance of Clonal/Oligoclonal T Cell Expansion in Patients with Lymphomatoid GranulomatosisTalkASCP Meeting2001
Phase II Study of Dose Adjusted EPOCH-Rituximab in Untreated High Risk Large B-Cell LymphomasTalkASCO Meeting2001
Rituximab May Overcome BCL-2 Associated Chemotherapy: Resistance in Untreated Diffuse Large B-Cell LymphomasTalkASH Meeting2001
Rituximab in the Treatment of Fludarabine (FAMP) Associated Autoimmune Thrombocytopenia (AT) in Chronic Lymphocytic Leukemia (CLL): Report of Three Cases from a Single InstitutionPosterAmerican Society of Clinical Oncology2001San Francisco, California
High Incidence of Occult Leptomeningeal Disease Detected by Flow Cytometry in at Risk Newly Diagnosed B-Cell LymphomasPosterAmerican Society of Hematology2001Orlando, Florida
Post Transplant Lymphoproliferative Disease: Clinical Manifestations, Treatment PrinciplesTalkNational Institutes of Health2001Bethesda, Maryland
A Phase II Study of Abbreviated Treatment (short-course) with EPOCH and Rituximab (EPOCH-R) in AIDS—Related Lymphoma (ARL): Preliminary Results on the Role of Rituximab in TreatmentTalkASH Meeting2000
Phase I Trial of 7-Hydroxystaurosporine (UCN-01) and Fludarabine Phosphate (FAMP): In Vivo Evidence of UCN-01 Induced Apoptosis in CLLTalkASH Meeting2000
Proto-Oncogene Expression and Adriamycin Uptake in Poor and Standard Prognosis Acute Myelogenous LeukemiaPosterAmerican Society of Hematology1995Seattle, Washington
In Vitro Cytosine Arabinoside (Ara-c) Sensitivity of Leukemia Cells from Chronic Myelogenous Leukemia (CML) PatientsPosterSigma Xi, The Scientific Research Society, Rush University Chapter1994
Bcl-2 Expression In Vivo in Acute Leukemia, Chronic Phase CML and Myeloid Blastic Crisis of CMLPosterAmerican Society of Hematology1993St. Louis, Missouri
Improved Results in Non-Seminomatous Germ Cell Tumors with Combination ChemotherapyTalkAssociation of Physicians of India1991Agra, India
Transporter P-Glycoprotein and In Vitro Chemo-Sensitivity-Correlation with In Vivo Response to Chemotherapy in Acute Myeloid LeukemiaTalkIndian Society of Oncology1991Madras, India
Multiple Myeloma-Clinical Experience in 50 Patients at Tata Memorial HospitalTalkBombay Hematology Group1990Bombay, India
Essential Thrombocythemia: A Clinico-Pathological Study of Five PatientsTalkBombay Hematology Group1989Bombay, India