Faculty Directory › UConn Health

Sidney M. Hopfer, PhD

Professor Emeritus, Pathology and Laboratory Medicine

NPI Number: null
Academic Office Location: Pathology and Laboratory Medicine UConn Health 263 Farmington Avenue Farmington, CT 06030-2235
Phone:	860-679-2665
Fax:	860-679-2154
Email:	hopfer@uchc.edu
Website(s):	Pathology and Laboratory Medicine

Education & Training
Committees & Organizations
Research
Publications
Presentations

Education

Degree	Institution	Major
BS	Colorado State University	Biology
MS	University of Connecticut	Pathobiology
PhD	University of Connecticut	Pathobiology

Degree

Institution

Major

Colorado State University

Biology

University of Connecticut

Pathobiology

PhD

University of Connecticut

Pathobiology

Awards

Name of Award/Honor	Awarding Organization
Clinical Scientist of the Year	Association of Clinical Scientists
Diploma of Honor	Association of Clinical Scientists
Young Investigator Award	Association of Clinical Scientists

Name of Award/Honor

Awarding Organization

Clinical Scientist of the Year

Association of Clinical Scientists

Diploma of Honor

Association of Clinical Scientists

Young Investigator Award

Association of Clinical Scientists

Name & Description	Category	Role	Type	Scope	Start Year	End Year
Cystic Fibrosis Foundation Newborn Screening Quality Improvement Consortium	Professional/Scientific Organization	Member	External	National	2012
Medical Laboratory Sciences Program	Professional/Scientific Organization	Member	UConn Health	University	2011
Quality Resource Manangement Committee: John Dempsey Hosptial	Professional/Scientific Organization	Member	External	Local	2009	2013
Association of Clinical Scientists: Awards Committee	Professional/Scientific Organization	Member	External	National	2006
State of Connecticut, Expert Genomics Advisory Panel	Advisory Committee	Member	External	State	2006
State of Connecticut, Dept of Public Health: Chemical Terrorism Disaster Advisory Board	Advisory Committee	Member	External	State	2004
Medical Advisory Committee Connecticut Poison Control Center	Professional/Scientific Organization	Member	External	State	2004
Annals of Clinical and Laboratory Science: Editorial Board	Editorial Board	Member	External	National	2004
Association of Clinical Scientists: Executive Committee	Professional/Scientific Organization	Member	External	National	1996	1999
Association of Clinical Scientists: Nominating Committee	Professional/Scientific Organization	Member	External	National	1995	1997
Associaton of Clinical Scientists	Professional/Scientific Organization	President	External	National	1994	1995
Association of Clinical Scientists: Awards Committee	Professional/Scientific Organization	Member	External	National	1993	1997
Association of Clinical Scientists	Professional/Scientific Organization	Vice-President	External	National	1993	1994
Association of Clinical Scientists: Credentials Committee	Professional/Scientific Organization	Member	External	National	1989	1992
Environmental Health Criteria Document for Nickel	Professional/Scientific Organization	Temporary Advisor	External	International	1989
Association of Clinical Scientists: Scientific Council	Professional/Scientific Organization	Member	External	National	1987
Association of Clinical Scientists: Membership Committee	Professional/Scientific Organization	Chairman	External	National	1984	1994
Association of Clinical Scientists: Membership Committee	Professional/Scientific Organization	Member	External	National	1983
American Association for Clinical Chemistry	Professional/Scientific Organization	Member	External	National

Name & Description

Journal Articles

Improvement in cystic fibrosis newborn screening program outcomes with genetic counseling via telemedicine.
Stalker, Heather J; Jonasson, Amy R; Hopfer, Sidney M; Collins, Melanie Sue Pediatric pulmonology 2023 Sep;
Improved pulmonary and growth outcomes in cystic fibrosis by newborn screening.
Collins, Melanie Sue; Abbott, Mary-Alice; Wakefield, Dorothy B; Lapin, Craig D; Drapeau, Ginny; Hopfer, Sidney M; Greenstein, Robert M; Cloutier, Michelle M Pediatric pulmonology 2008 Jul;43(7):648-55
State-wide hospital clinical laboratory plan for measuring cholinesterase activity for individuals suspected of exposure to nerve agent chemical weapons.
Wu, Alan H B; Smith, Andrew; McComb, Robert; Bowers, George N; Makowski, Gregory S; McKay, Charles A; Vena, Jason; McDonagh, John; Hopfer, Sidney; Sena, Salvatore F; Malkus, Herbert; Forte, Elaine; Kelly, Katherine Clinical toxicology (Philadelphia, Pa.) 2008 Feb;46(2):110-6
Effect of protein on hemoglobin and hematocrit assays with a conductivity-based point-of-care testing device: comparison with optical methods.
Hopfer, Sidney M; Nadeau, Francesca L; Sundra, Marilyn; Makowski, Gregory S Annals of clinical and laboratory science 2004 Jan;34(1):75-82
Single tube multiplex PCR detection of 27 cystic fibrosis mutations and 4 polymorphisms using neonatal blood samples collected on Guthrie cards.
Makowski, Gregory S; Nadeau, Francesca L; Hopfer, Sidney M Annals of clinical and laboratory science 2003 Jan;33(3):243-50
Polymerase chain reaction amplification of Guthrie card deoxyribonucleic acid: extraction of nucleic acid from filter matrices.
Makowski, G S; Davis, E L; Nadeau, F; Hopfer, S M Annals of clinical and laboratory science 1998 Jan;28(4):254-9
Amplification of Guthrie card DNA: effect of guanidine thiocyanate on binding of natural whole blood PCR inhibitors.
Makowski, G S; Davis, E L; Hopfer, S M Journal of clinical laboratory analysis 1997 Jan;11(2):87-93
Measurement of maternal folate status and risk of neural tube defects.
Makowski, G S; Hopfer, S M Clinical chemistry 1997 Jan;43(1):185-6
Outcomes assessment of a residency program in laboratory medicine.
Morse, E E; Pisciotto, P T; Hopfer, S M; Makowski, G; Ryan, R W; Aslanzadeh, J Annals of clinical and laboratory science 1997 Jan;27(6):428-33
The effect of storage on Guthrie cards: implications for deoxyribonucleic acid amplification.
Makowski, G S; Davis, E L; Hopfer, S M Annals of clinical and laboratory science 1996 Jan;26(5):458-69
Enhanced direct amplification of Guthrie card DNA following selective elution of PCR inhibitors.
Makowski, G S; Davis, E L; Aslanzadeh, J; Hopfer, S M Nucleic acids research 1995 Sep;23(18):3788-9
In situ PCR amplification of Guthrie card DNA to detect cystic fibrosis mutations.
Makowski, G S; Aslanzadeh, J; Hopfer, S M Clinical chemistry 1995 Mar;41(3):477-9
Intraarticular carcinogenesis bioassays of CoCrMo and TiAlV alloys in rats.
Lewis, C G; Belniak, R M; Plowman, M C; Hopfer, S M; Knight, J A; Sunderman, F W The Journal of arthroplasty 1995 Feb;10(1):75-82
Detection of cystic fibrosis delta F508 mutation by anti-double-stranded DNA antibody.
Hopfer, S M; Makowski, G S; Davis, E L; Aslanzadeh, J Annals of clinical and laboratory science 1995 Jan;25(6):475-84
In vitro characteristics of white cell-reduced single-unit platelet concentrates stored in syringes.
Pisciotto, P T; Snyder, E L; Snyder, J A; Frattaroli, S; Hopfer, S M; Rinder, H M; Smith, B R Transfusion 1994 May;34(5):407-11
Malformations persist after metamorphosis of Xenopus laevis tadpoles exposed to Ni2+, Co2+, or Cd2+ in FETAX assays.
Plowman, M C; Grbac-Ivankovic, S; Martin, J; Hopfer, S M; Sunderman, F W Teratogenesis, carcinogenesis, and mutagenesis 1994 Jan;14(3):135-44
A nickel-binding serpin, pNiXa, induces maturation of Xenopus oocytes and shows synergism with oncogenic ras-p21 protein.
Haspel, J; Sunderman, F W; Hofper, S M; Henjum, D C; Brandt-Rauf, P W; Weinstein, I B; Nishimura, S; Yamaizumi, Z; Pincus, M R Research communications in chemical pathology and pharmacology 1993 Feb;79(2):131-40
Embryotoxicity and teratogenicity of Cu2+ and Zn2+ for Xenopus laevis, assayed by the FETAX procedure.
Luo, S Q; Plowman, M C; Hopfer, S M; Sunderman, F W Annals of clinical and laboratory science 1993 Jan;23(2):111-20
Mg(2+)-deprivation enhances and Mg(2+)-supplementation diminishes the embryotoxic and teratogenic effects of Ni2+, Co2+, Zn2+, and Cd2+ for frog embryos in the FETAX assay.
Luo, S Q; Plowman, M C; Hopfer, S M; Sunderman, F W Annals of clinical and laboratory science 1993 Jan;23(2):121-9
Ocular malformations of Xenopus laevis exposed to nickel during embryogenesis.
Hauptman, O; Albert, D M; Plowman, M C; Hopfer, S M; Sunderman, F W Annals of clinical and laboratory science 1993 Jan;23(6):397-406
pNiXa, a Ni(2+)-binding protein in Xenopus oocytes and embryos, shows identity to Ep45, an estrogen-regulated hepatic serpin.
Beck, B L; Henjum, D C; Antonijczuk, K; Zaharia, O; Korza, G; Ozols, J; Hopfer, S M; Barber, A M; Sunderman, F W Research communications in chemical pathology and pharmacology 1992 Jul;77(1):3-16
Teratogenicity of cadmium chloride in the South African frog, Xenopus laevis.
Sunderman, F W; Plowman, M C; Hopfer, S M IARC scientific publications 1992 Jan;(118):249-56
Cobalt in periprosthetic soft tissue. Observations in 6 revision cases.
Lewis, C G; Belniak, R M; Hopfer, S M; Sunderman, F W Acta orthopaedica Scandinavica 1991 Oct;62(5):447-50
In vitro characteristics of volume-reduced platelet concentrate stored in syringes.
Pisciotto, P T; Snyder, E L; Napychank, P A; Hopfer, S M Transfusion 1991 Jun;31(5):404-8
Teratogenicity of Ni2+ in Xenopus laevis, assayed by the FETAX procedure.
Hopfer, S M; Plowman, M C; Sweeney, K R; Bantle, J A; Sunderman, F W Biological trace element research 1991 Jun;29(3):203-16
Selection of low frequency tumor cells from cell culture by growth in nude mice.
Nichols, W W; Hill, R B; Bradt, C I; Kraynak, A; Bradley, M O; Sunderman, F W; Hopfer, S M Cancer genetics and cytogenetics 1991 May;53(1):57-66
Embryotoxicity and teratogenicity of cadmium chloride in Xenopus laevis, assayed by the FETAX procedure.
Sunderman, F W; Plowman, M C; Hopfer, S M Annals of clinical and laboratory science 1991 Jan;21(6):381-91
Teratogenicity of cobalt chloride in Xenopus laevis, assayed by the FETAX procedure.
Plowman, M C; Peracha, H; Hopfer, S M; Sunderman, F W Teratogenesis, carcinogenesis, and mutagenesis 1991 Jan;11(2):83-92
Carcinogenesis bioassays of nickel oxides and nickel-copper oxides by intramuscular administration to Fischer-344 rats.
Sunderman, F W; Hopfer, S M; Plowman, M C; Knight, J A Research communications in chemical pathology and pharmacology 1990 Oct;70(1):103-13
Chromosomal abnormalities and gene amplification in renal cancers induced in rats by nickel subsulfide.
Sunderman, F W; Hopfer, S M; Nichols, W W; Selden, J R; Allen, H L; Anderson, C A; Hill, R; Bradt, C; Williams, C J Annals of clinical and laboratory science 1990 Jan;20(1):60-72
Cross-shift and chronic effects of stainless-steel welding related to internal dosimetry of chromium and nickel.
Kilburn, K H; Warshaw, R; Boylen, C T; Thornton, J C; Hopfer, S M; Sunderman, F W; Finklea, J American journal of industrial medicine 1990 Jan;17(5):607-15
Effects of nickel chloride on lactating rats and their suckling pups, and the transfer of nickel through rat milk.
Dostal, L A; Hopfer, S M; Lin, S M; Sunderman, F W Toxicology and applied pharmacology 1989 Nov;101(2):220-31
Protein blotting method for detection of nickel-binding proteins.
Lin, S M; Hopfer, S M; Brennan, S M; Sunderman, F W Research communications in chemical pathology and pharmacology 1989 Sep;65(3):275-88
Toxicity to alveolar macrophages in rats following parenteral injection of nickel chloride.
Sunderman, F W; Hopfer, S M; Lin, S M; Plowman, M C; Stojanovic, T; Wong, S H; Zaharia, O; Ziebka, L Toxicology and applied pharmacology 1989 Aug;100(1):107-18
Nickel absorption and kinetics in human volunteers.
Sunderman, F W; Hopfer, S M; Sweeney, K R; Marcus, A H; Most, B M; Creason, J Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1989 May;191(1):5-11
Serum nickel concentrations in hemodialysis patients with environmental exposure.
Hopfer, S M; Fay, W P; Sunderman, F W Annals of clinical and laboratory science 1989 May;19(3):161-7
Cobalt, chromium, and nickel concentrations in body fluids of patients with porous-coated knee or hip prostheses.
Sunderman, F W; Hopfer, S M; Swift, T; Rezuke, W N; Ziebka, L; Highman, P; Edwards, B; Folcik, M; Gossling, H R Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1989 Jan;7(3):307-15
Direct analysis of platinum in plasma and urine by electrothermal atomic absorption spectrophotometry.
Hopfer, S M; Ziebka, L; Sunderman, F W; Sporn, J R; Greenberg, B R Annals of clinical and laboratory science 1989 Jan;19(6):389-96
Hypothermia and deranged circadian rhythm of core body temperature in nickel chloride-treated rats.
Hopfer, S M; Sunderman, F W Research communications in chemical pathology and pharmacology 1988 Dec;62(3):495-505
Acute nickel toxicity in electroplating workers who accidently ingested a solution of nickel sulfate and nickel chloride.
Sunderman, F W; Dingle, B; Hopfer, S M; Swift, T American journal of industrial medicine 1988 Jan;14(3):257-66
Nickel analysis by electrothermal atomic absorption spectrometry.
Sunderman, F W; Hopfer, S M; Crisostomo, M C Methods in enzymology 1988 Jan;158382-91
Pulmonary histopathology of rats following parenteral injections of nickel chloride.
Knight, J A; Rezuke, W N; Gillies, C G; Hopfer, S M; Sunderman, F W Toxicologic pathology 1988 Jan;16(3):350-9
Hypophosphatemic rickets with hypercalciuria and microglobulinuria.
Carey, D E; Hopfer, S M The Journal of pediatrics 1987 Dec;111(6 Pt 1):860-3
Acute thymic involution and increased lipoperoxides in thymus of nickel chloride-treated rats.
Knight, J A; Rezuke, W N; Wong, S H; Hopfer, S M; Zaharia, O; Sunderman, F W Research communications in chemical pathology and pharmacology 1987 Mar;55(3):291-302
Lipoperoxides in plasma as measured by liquid-chromatographic separation of malondialdehyde-thiobarbituric acid adduct.
Wong, S H; Knight, J A; Hopfer, S M; Zaharia, O; Leach, C N; Sunderman, F W Clinical chemistry 1987 Feb;33(2 Pt 1):214-20
Physicochemical characteristics and biological effects of nickel oxides.
Sunderman, F W; Hopfer, S M; Knight, J A; McCully, K S; Cecutti, A G; Thornhill, P G; Conway, K; Miller, C; Patierno, S R; Costa, M Carcinogenesis 1987 Feb;8(2):305-13
Increased nickel concentrations in body fluids of patients with chronic alcoholism during disulfiram therapy.
Hopfer, S M; Linden, J V; Rezuke, W N; O'Brien, J E; Smith, L; Watters, F; Sunderman, F W Research communications in chemical pathology and pharmacology 1987 Jan;55(1):101-9
Metabolism of Vitamin D
Adams ND, Hopfer SM Clinical Chemistry 1987 Jan;271-7
Ethene (ethylene) and ethane exhalation in Ni[II]-treated rats, using an improved rebreathing apparatus.
Knight, J A; Hopfer, S M; Reid, M C; Wong, S H; Sunderman, F W Annals of clinical and laboratory science 1986 Jan;16(5):386-94
Rapid analysis of nickel in urine by electrothermal atomic absorption spectrophotometry.
Sunderman, F W; Hopfer, S M; Crisostomo, M C; Stoeppler, M Annals of clinical and laboratory science 1986 Jan;16(3):219-30
Nickel concentrations in serum of patients with acute myocardial infarction or unstable angina pectoris.
Leach, C N; Linden, J V; Hopfer, S M; Crisostomo, M C; Sunderman, F W Clinical chemistry 1985 Apr;31(4):556-60
Blood nickel concentrations in patients with stainless-steel hip prostheses.
Linden, J V; Hopfer, S M; Gossling, H R; Sunderman, F W Annals of clinical and laboratory science 1985 Jan;15(6):459-64
Increased lipid peroxidation in tissues of nickel chloride-treated rats.
Sunderman, F W; Marzouk, A; Hopfer, S M; Zaharia, O; Reid, M C Annals of clinical and laboratory science 1985 Jan;15(3):229-36
Association between erythrocytosis and renal cancers in rats following intrarenal injection of nickel compounds.
Sunderman, F W; McCully, K S; Hopfer, S M Carcinogenesis 1984 Nov;5(11):1511-7
Rapid analysis of nickel in serum and whole blood by electrothermal atomic absorption spectrophotometry.
Sunderman, F W; Crisostomo, M C; Reid, M C; Hopfer, S M; Nomoto, S Annals of clinical and laboratory science 1984 May;14(3):232-41
Increased immunoreactive erythropoietin in serum and kidney extracts.
Hopfer, S M; Sunderman, F W; Reid, M C; Goldwasser, E Research communications in chemical pathology and pharmacology 1984 Feb;43(2):299-305
Studies of the pathogenesis of arteriosclerosis induced in rats by intrarenal injection of a carcinogen, nickel subsulfide.
Hopfer, S M; Sunderman, F W; McCully, K S; Reid, M C; Liber, C; Spears, J R; Serur, J Annals of clinical and laboratory science 1984 Jan;14(5):355-65
The elimination of equine strongyles and hematological and pathological consequences following larvicidal doses of thiabendazole.
Hopfer, S M; Van Kruiningen, H J; Daniels, W H Veterinary parasitology 1984 Jan;14(1):21-32
Effects of unilateral nephrectomy on erythrocytosis and arteriosclerosis induced in rats by intrarenal injection of nickel subsulfide.
McCully, K S; Sunderman, F W; Hopfer, S M; Kevorkian, C B; Reid, M C Virchows Archiv. A, Pathological anatomy and histology 1982 Jan;397(3):251-9
Erythrocytosis, glomerulomegaly, mesangial hyperplasia, sialyl hyperplasia, and arteriosclerosis induced in rats by nickel subsulfide.
McCully, K S; Rinehimer, L A; Gillies, C G; Hopfer, S M; Sunderman, F W Virchows Archiv. A, Pathological anatomy and histology 1982 Jan;394(3):207-20
Erythropoietin-mediated erythrocytosis in rodents after intrarenal injection of nickel subsulfide.
Sunderman, F W; Hopfer, S M; Reid, M C; Shen, S K; Kevorkian, C B The Yale journal of biology and medicine 1982 Jan;55(2):123-36
Spectrophotometric assay for urinary N-acetyl-beta-D-glucosaminidase activity.
Horak, E; Hopfer, S M; Sunderman, F W Clinical chemistry 1981 Jul;27(7):1180-5
Effects of intrarenal injection of nickel subsulfide in rodents.
Hopfer, S M; Sunderman, F W; Morse, E E; Fredrickson, T N Annals of clinical and laboratory science 1980 Jan;10(1):54-64
Induction of renal cancers in rats by intrarenal injection of nickel subsulfide.
Sunderman, F W; Maenza, R M; Hopfer, S M; Mitchell, J M; Allpass, P R; Damjanov, I Journal of environmental pathology and toxicology 1979 Jul;2(6):1511-27
Increased serum erythropoietin activity in rats following intrarenal injection of nickel subsulfide.
Hopfer, S M; Sunderman, F W; Fredrickson, T N; Morse, E E Research communications in chemical pathology and pharmacology 1979 Jan;23(1):155-70
Nickel-induced erythrocytosis: efficacies of nickel compounds and susceptibilities of rat strains.
Hopfer, S M; Sunderman, F W; Fredrickson, T N; Morse, E E Annals of clinical and laboratory science 1978 Sep;8(5):396-402
Manganese inhibition of nickel subsulfide induction of erythrocytosis in rats.
Hopfer, S M; Sunderman, F W Research communications in chemical pathology and pharmacology 1978 Feb;19(2):337-45
Molecular weight of human factor VIII procoagulant activity.
Rick, M E; Hoyer, L W Thrombosis research 1975 Dec;7(6):909-16
Ontogenesis of adrenergic and cholinergic neuroeffector transmission in chick embryo heart.
Pappano, A J; Löffelholz, K The Journal of pharmacology and experimental therapeutics 1974 Dec;191(3):468-78
Diminished virulence of glucan synthesis-defective mutants of Streptococcus mutans.
Tanzer, J M; Freedman, M L; Fitzgerald, R J; Larson, R H Infection and immunity 1974 Jul;10(1):197-203
Cobalt Concentration Gradient in Soft Tissue Adjacent to Failed Hip Prostheses
Lewis, C.G, Belniak, R.M., Hopfer, S.M. and Sunderman, F.W., Jr. Acta. Orthopaed. Scand 62447-450
Extraction of Genomic DNA from Guthrie Card Filter Paper: Extraction of Nucleic Acids from Filter Matrices
Makowski, G.S., Davis, E.L. and Hopfer, S.M. Ann Clin Lab Sci 28254-259
Genotype-Phenotype Relationships in Patients with Cystic Fibrosis
Hopfer, S.M. and Makowski, G.S. Ann Clin Lab Sci 26356
Platinum Analysis in Body Fluids by Electrothermanl Atomic Absorption Spectrophotometry
Hopfer, S.M., Ziebka, L., Greenberg, B.R., Sporn, J. and Sunderman, F.W., Jr. Ann. Clin. Lab. Sci. 19316-317
Thermoregulatory Impairment in Nickel-Treated Rats
Hopfer, S.M., Leach, C.A., Jr. and Sunderman, F.W., Jr. Ann. Clin. Lab. Sci. 18417-418
Vitamin D Metabolism
Adams, N.D. and Hopfer, S.M. Am. Soc. Clin. Pathol. Clin. Chem 271-8

Books

Hopfer, S.M. Tietz Clinical Guide to Laboratory Tests

Book Chapters

Detection of oligoclonal bands in patients with neurologic diseases: comparison between agarose gel-, immunofixation- and isoelectric-focusing electrophoresis.
Shan, D E; Yeh, S I Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 1998 Jul;61(7):375-81
Search for molecular mechanisms in the genotoxicity of nickel.
Sunderman, F W Scandinavian journal of work, environment & health 1993 Jan;19 Suppl 175-80
Acute Depletion of Pulmonary Lavage Cells and Enhanced Lipid Peroxidation in Alveolar Macrophages Following Parenteral Administration of Nickel Chloride to Rats
Sunderman, F.W., An, L.L., Zaharia, O., Wong, S.H-Y. and Hopfer, S.M. Pharmacology 817-820
Bioassay of Serum Erythropoietin Activity
Hopfer, S.M Manual on the Laboratory Diagnosis and Monitoring of Cancer 223-234
Bioassay of Serum Erythropoietin Activity
Hopfer, S.M. Manual on Seminar on Diagnostic Hematology
Bioassay of Serum Erythropoietin Activity
Hopfer, S.M., Sunderman, F.W., Fredrickson, T.N. and Morse, E.E. Manual on Clinical Pathology of Cancer of the Endocrine Glands and Target Organs 115-124
Comparison of Immunoassays for Human Chorionic Gonadotrophin Using Polyclonal and Monoclonal Antisera
Horak, E. and Hopfer, S.M. Manual on Clinical Pathology of Reproductive Systems 97-110
Compositional Changes in Sexually Differentiated Forms of Hepatic Cytochrome P-450 in the Diabetic Rat
Thummel, K.E., Hopfer, S.M. and Schenkman, J.B. Highlights of Modern Biochemistry 247-256
Correlation Between the Carcinogenic Activities of Nickel Compounds and Their Potencies for Stimulating Erythropoiesis in Rats
Sunderman, F.W., Jr. and Hopfer, S.M. Biological Aspects of Metals and Metal-Related Diseases 171-181
Identification of Three Nickel-Binding Proteins that may be Molecular Targets for Teratogenesis and Embryotoxicity in Xenopus Laevis
Sunderman, F.W. Jr., Antonijczuk, A., Antonijczuk, K., Grbac-Ivankovic, S., Hopfer, S., Plowman, M.C., Slaisova, O. and Varghese, A.H. Proceedings of the Eight International Symposium on Trace Elements in Man and Animals (TEMA-8) 798-806
Measurement of 5'-Nucleotidase
Stojanovic, T., Horak,E. and Hopfer, S.M. Manual on Diseases of the Liver 49-60
Measurement of Lipoperoxides in Plasma
Hopfer, S.M., Wong, S.W-Y. and Knight, J.A. Manual on Toxicology 81-93
Measurement of Phagocytic Actibity of Mononuclear Cells by Fluorescent Microscopy of Ingested Polystyrene Microspheres
Hopfer, S.M. Ziebka, L. and Sunderman, F.W.Jr Manual on Seminar on Diagnostic Hematology 129-136
Measurement of Trace Metals in Serum by Electrothermal Atomic Absorption Spectrophotometry
Hopfer, S.M. and Sunderman, F.W., Jr. Manual on Laboratory Diagnosis of Cardiovascular Disorders 169-181
Neonatal Cystic Fibrosis Screening: Implications of Apparent Seasonal Variations in Immunoreactive Trypsinogen Concentration
Nadeau, F.L., Makowski, G.S., and Hopfer, S.M. Proceedings of the Eleventh National Neonatal Screening Symposium 200-201
Nickel-Induced Derangements of Thermoregulation
Hopfer, S.M. and Sunderman, F.W.,Jr. Nickel and Human Health: Current Perspectives 561-571
Premature Infants Treated with Furosemide have Increased Urinary Calcium and Unchanged Urinary Citrate Excretion Compared to Controls
Adams, N.D., Rowe, J.C., Sawhney, R., Lazar, A.M., Horak, E., Hopfer, S.M. and Condren, TB Proceedings of the Sixth International Symposium on Urolithiasis 379-382
Quantitative Determination of Amino Acids in Plasma and Urine by High Pressure Ion Exchange Chromatography
Horak, E. and Hopfer, S.M. Manual on Laboratory Diagnosis of Disorders of the Fetus, Newborn, and Infant 19-36
Radioimmumoassays of Erythropoietin Concentrations in Serum and Kidney Extracts of Rats with Nickel Subsulfide-Induced Erythrocytosis
Hopfer, S.M., Sunderman, F.W., Jr. and Goldwasser, E. Progress in Nickel Toxicology 133-136
Selective Removal of PCR Inhibitors from Guthrie card Bloodspots: Rapid Detection of Cystic Fibrosis Mutations in Exon 10 and 11
Hopfer, S.M., Makowski, G.S., and Davis, E.L. Proceedings of the Eleventh National Neonatal Screening Symposium 104-106
Spectrophotometric Assay of N-Acetyl-Beta-D-Glucosaminidase Activity in Urine
Horak, E., Hopfer, S.M. and Sunderman, F.W., Jr. Manual on Laboratory Diagnosis and Monitoring of Disorders of the Kidney 157-170
Teratogenicity of Cadmium Chloride in the South African Frog, Xenopus laevis
Sunderman, F.W., Jr., Plowman, M.C. and Hopfer, S.M. Cadmium in the Human Environment: Toxicity and Carcinogenicity 249-255
Teratogenicity of Ni2+ in Xenopus laevis
Hopfer, S.M., Plowman, M.C. Bantle, J.A,. and Sunderman, F.W., Jr International Symposium on Trace Elements in Health and Disease 169-175
The FETAX Test for Teratogenicity of Chemicals and Environmental Samples
Hopfer, S.M., Plowman, M.C. and Sunderman, F.W. Jr. Manual on Laboratory Diagnosis of Disorders of the Fetus, Newborn, and Early Childhood 79-86
The Measurement of Estradiol by Direct Radioimmunoassay
Horak, E. and Hopfer S.M. Manual on Clinical Pathology of Reproductive Systems 229-236

Abstracts

Joint counts to assess rheumatoid arthritis for clinical research and usual clinical care: advantages and limitations.
Sokka, Tuulikki; Pincus, Theodore Rheumatic diseases clinics of North America 2009 Nov;35(4):713-22, v-vi
Trace element status in alcoholism before and during disulfiram treatment.
Grandjean, P; Kristensen, K; Jørgensen, P J; Nielsen, G D; Andersen, O Annals of clinical and laboratory science 1990 Jan;20(1):28-35
63Ni2+-Binding Proteins in Xenopus Oocytes and Embryos
Sunderman, F.W., Jr., Henjum, D.C., Beck, B.L., Makowski, G.M., Nomoto, S., Korza, G., Ozols, J., Hopfer, S.M., and Barber, A.: Ann. Clin. Lab. Sci. 21363
Changes in LDH Isoenzymes in Bronchoalveolar Lavage Fluid and in Lung Tissue at Various Stages During the Development of Bleomycin-Induced Pulmonary Fibrosis in the Rat
Thrall, R.S., Parkinson, D. and Hopfer, S.M. Am. Rev. Resp. Dis. 12764
Comparisons of the Efficacies of Nickel Compounds for Induction of Erythrocytosis Following Injection in Rats
Hopfer, S.M., Sunderman, F.W., Jr., Fredrickson, T.N. and Morse, E.E. Ann. Clin. Lab. Sci 7369-370
Comparisons of the Efficacies of Nickel Compounds for Induction of Erythrocytosis Following Intrarenal Injection in Rats
Hopfer, S.M., Sunderman, F.W., Jr., Fredrickson, T.N., and Morse, E.E. Proc. Amer. Soc. Hematol 109
Cystic Fibrosis or CFTR-Related Metabolic Syndrome (CRMS) A Diagnosis Obtained from Newborn Screening?
Hopfer, S.M. AnClin Lab Sci 43341
Detection of Hybridization Products of the F508 Mutation in Neonates with Cystic Fibrosis Using a Monoclonal Antibody Against Double-Stranded DNA
Hopfer, S.M., Makowski, G.S. and Aslandadeh, J. Ann Clin Lab Sci 24469
Detection of Plasma Factor XIII (transglutaminase) with a Fluorescent Polyamine Following Electrophoresis
Makowski, G.S. and Hopfer, S.M. Clin Chem 401124
Differences in Blood and Urine in Furosemide (F) Treated VlBW Infants With and Without Nephrocalcinosis (NC)
Adams, N.D., Rowe, J.C., Lazar, A.M., Horak, E., Hopfer, S.M., Condren, T.B. Proc. Amer. Ped. Soc
Effects of Unilateral Intrarenal Administration of Nickel Subsulfide to Rats on Erythropoietin Concentrations in Serum and Kidney Extracts and on Plasma Renin and Renin-Substrate Concentrations
Hopfer, S.M., Sunderman, F.W., Jr., Goldwasser, E. and Fyrquist, F. Ann. Clin. Lab. Sci. 15344-345
Embryotoxicity and teratogenecity of Co2+ in Xenopus Laevis
Hopfer, S.M., Plowman, M.C., Peracha, H. and Sunderman, F.W., Jr. Ann. Clin. Lab. Sci. 21364
Environmental Impurity: Singing Canaries vs Freaky Frogs
Hopfer, S.M. Comparitive Pathology Seminar Series
Erythropoietin-Mediated Erythrocytosis in Rodents Following Intrarenal Injection of Nickel Subsulfide
Sunderman, F.W., Jr., Hopfer, S.M., Reid, M.C., Shen, S.K and Delaney, L. Exper. Hemat 8191
Evaluation of Ionized Calcium in Arterial and Venous Specimens: Comparison of Whole Blood (iSTAT) and Plasma-Serum (Corning 634) Analyzer
Makowski, G.S., Schuler, C.K., Whitfield, D., McNally, D.P. and Hopfer, S.M. Clin Chem 41S176-S177
Evaluation of the Incstar 25-Hydroxyvitamin D (25-OH-D) 125I RIA Kit
King, E.H., Hopfer, S.M., and Stone, J.A. Clin Chem 401035
Extraction and Preliminary Characterization of Polymerase Chain Reaction (PCR) Inhibitors from Guthrie Card Bloodspots: Detection of Genetic Mutations in Neonates
Hopfer. S.M., Makowski, G.S. and Aslanzadeh, J. Ann Clin Lab Sci 25343
Extraction of Genomic DNA from Guthrie Card Filter Paper: Avidity of Nucleic Acids for Filter Matrices
Makowski, G.S., Davis, E.L., and Hopfer, S.M. Clin Chem 44A41
Factors which Influence the Induction of Erythrocytosis by Intrarenal Injection of Nickel Subsulfide
Sunderman, F.W., Jr., Reid, M.C., Delaney, L., Shen, S.K. and Hopfer, S.M. Ann. Clin. Lab. Sci. 10453
Folate and Neural Tube Defects: Analytical Considerations
Hopfer, S.M. and Makowski, G.S. Ann Clin Lab Sci 2777
Hypernickelemia in Patients Receiving Disulfiram
Hopfer, S.M., Linden, J.V., Crisostomo, C., O'Brien, J.E. and Sunderman, F.W., Jr. Ann. Clin. Lab. Sci. 14319
Identification of Neonates with Cystic Fibrosis Following Multiplex PCR Amplification of Eight Common Mutations in a Neonatal Screening Program
Makowski, G.S., Aslanzadeh, J., and Hopfer, S.M. Ann Clin Lab Sci 24469-470
Induction of Renal Carcinomas by Intrarenal Injection of Nickel Subsulfide in Rats
Sunderman, F.W., Jr., Maenza, R.M., Hopfer, S.M., Mitchell, J.M., Allpass, P.R. and Damjanov, I. Proc. Amer. Assoc. Cancer Res. 19127
Isoelectric Focusing of Spinal Fluid Proteins
Hopfer, S.M. Ann. Clin. Lab. Sci. 2260-61
Measurement of 25-Hydroxycholecalciferol in Human Serum Using Sephadex LH-20 and High-Performance Liquid Chromatography
Hopfer, S.M., Horak, E., Person, N., and Wong, S.H-Y. Ann. Clin. Lab. Sci. 13350
Neonatal Screening for Cystic Fibrosis: Comparison of Two DNA-Based Algorithms
Hopfer, S.M., Makowski, G.S. Ann Clin Lab Sci 35(2):206
Newborn Screening for Cystic Fibrosis: Benefits of Molecular Detection Methods for F508 and Non-F508 Mutations
Hopfer, S.M., Nadeau, F.L. and Makowski, G.S. Ann Clin Lab Sci 28180-181
Nickel Concentrations in Body Fluids of Healthy Adults and Hemodialysis Patients in Sudbury, Ontario, Canada
Hopfer, S.M., Sunderman, F.W., Jr. and Fay, W.P. Ann. Clin. Lab. Sci. 17274-275
Novel Approaches for Collection of DNA for Genetic and Epidemiological Studies
Hopfer, S.M., Kolakoski, C.J., Avery, L.A., Senh, M.C., Ryan, R.W. Ann Clin Lab Sci 36228
Pathologic and Hematologic Sequellae of Intrarenal Injection of Nickel Subsulfide Induced Erythrocytosis in Rats
Hopfer, S.M., Fredrickson, T.N., Morse, E.E. and Sunderman. F.W., Jr. Ann. Clin. Lab. Sci. 9435
Radioimmunoassays of Erythropoietin Concentrations in Serum and Kidney Extracts of Rats with Nickel Subsulfide-Induced Erythrocytosis
Ann. Clin. Lab. Sci. Hopfer, S.M., Sunderman, F.W., Jr. and Goldwasser, E. 14407
Renal Carcinoma Cell Line Derived from Nickel Subsulfide-Induced Rat Tumor
Yamase, H., Marzouk, A., Liber, C., Hopfer, S.M., Helmut., M., Donskoy, M., Gillies, C., and Sunderman, F.W., Jr.: Ann. Clin. Lab. Sci. 15347
Silk Purses from Sow’s Ears - An Outcome Analysis of a Laboratory Medicine Residency Program
Morse, E.E., Pisciotto, P.T., Hopfer, S.M., Makowski, G.S., Ryan, R.R., Aslanzadeh, J. and Sunderman, F.W. Jr. Ann Clin Lab Sci 27316
Strain Differences in Susceptibility of Rats to Induction of Erythrocytosis After Intrarenal Injection of Nickel Subsulfide
Hopfer, S.M., Sunderman, F.W., Jr., Fredrickson, T.N., and Morse, E.E. Ann. Clin. Lab. Sci 354-355
Test Consolidation with Pre-Analytical Automation in a Small University Hospital Laboratory
Hopfer, S.M., Makowski, G.S. Ann Clin Lab Sci 34(3):359
Whole Blood and Serum Storage on Filter Paper (Guthrie Cards) for Immunoassay Analysis
Hopfer, S.M. and Makowski, G.S. Ann Clin Lab Sci 31307

Conference Papers

Pathological reactions in lung, liver, thymus, and spleen of rats after subacute parenteral administration of nickel sulfate.
Knight, J A; Plowman, M R; Hopfer, S M; Sunderman, F W Annals of clinical and laboratory science 1991 Jan;21(4):275-83
Platinum in blood mononuclear cells from patients after cisplatin therapy.
Sunderman, F W; Sporn, J; Hopfer, S M; Sweeney, K R; Chakraborty, N G; Greenberg, B Annals of clinical and laboratory science 1990 Jan;20(6):379-84

Letters

Changes in academic productivity: implications for clinical laboratory research and development.
Makowski, G S; Hopfer, S M; Tsongalis, G J; Wu, A H Clinical chemistry 2000 Feb;46(2):303-5
Mini-gel PAGE for enhanced resolution of polymerase chain reaction detection of delta F508 deletion in cystic fibrosis.
Makowski, G S; Aslanzadeh, J; Hopfer, S M Clinical chemistry 1993 Oct;39(10):2204-5

Newsletters

Deformed Frogs Remain a Mystery
Hopfer, S.M. and Mokowski, G.S. The Center for Environmental Health Newsletter 710-11

Other

Correlation between carcinogenic activities of nickel compounds and their potencies for stimulating erythropoiesis in rats
Sunderman Jr. F.S., Hopfer S.M. Proceedings of the American Association for Cancer Research 1982 Jan;Vol. 23
Erythropoietin-mediated erythrocytosis in rodents following intrarenal injection of nickel subsulfide
Sunderman Jr. F.W., Hopfer S.M., Reid M.C. Experimental Hematology 1980 Jan;8(Suppl. 8):191-196
Induction of renal carcinomas by intrarenal injection of nickel subsulfide in rats
Sunderman Jr. F.W., Maenza R.M., Hopfer S.M. Proceedings of the American Association for Cancer Research 1978 Jan;Vol. 19
Equine Strongyle Eradication with Larvicidal Thiabendazole
Hopfer, S.M. 1-58

Reviews

Cystic fibrosis: molecular approaches to diagnosis.
Makowski, G S; Hopfer, S M Annals of clinical and laboratory science 1998 Jan;28(6):380-5

Title or Abstract	Type	Sponsor/Event	Date/Year	Location
Consolidation and Automation: A Safer Environment	Lecture	Beckman Coulter Symposia	2004	White Plains, New York
Laboratory Redesign with Automation: An Ongoing Process	Lecture	Beckman Coulter Symposia	2003	White Plains, New York
Laboratory Redesign with Automation: An Ongoing Process	Lecture	Beckman Coulter Symposia	2003	Boston, Massachusetts
Consolidation and Automation in a Small Hospital Laboratory	Lecture	Beckman Coulter Symposia	2002	White Plains, New York
Consolidation and Automation in a Small Hospital Laboratory	Lecture	Beckman Coulter Symposia	2002	Philadelphia, Pennsylvania
Consolidation and Automation in a Small Hospital Laboratory	Lecture	Beckman Coulter Symposia	2002	Waltham, Massachusetts
Decisions for Laboratory Redesign with Automation	Lecture	American Society for Clinical Laboratory Science	2002	Hartford, Connecticut
Newborn Screening for Cystic Fibrosis	Lecture	Assciation of Public Health Laboratories	2001	Washington, DC
Detection of Cystic Fibrosis in a 24 Week Old Infant: Application of Neonatal Screening in Premature Populations	Lecture	National Neonatal Screening Symposium	1998	San Diego, California
Newborn Screening for Cystic Fibrosis: Early Detection of Infants with Non-?F508 Mutations	Lecture	National Neonatal Screening Symposium	1998	San Diego, California
Detection of Cystic Fibrosis in a 24 Week-Old Infant: Application of Neonatal Screening in Premature Populations	Talk	Neonatal Screening Symposium	1998	San Diego, California
Newborn Screening for Cystic Fibrosis: Early Detection of Infants with Non-?F508 Mutations	Talk	National Neonatal Screening Symposium	1998	San Diego, California
Amplification of Guthrie Card DNA: Differential Binding of Natural PCR Inhibitors to Guanidine Thiocyanate-Impregnated Filter Paper	Lecture	3rd International Neonatal Screening Symposium	1996	Boston, Massachusetts
Triad Approach for Detection of Cystic Fibrosis in a Neonatal Screening Program: Identification of an Infant Homozygous for the 2789+G?A Mutation	Lecture	International Neonatal Screening Symposium	1996	Boston, Massachusetts
Amplification of Guthrie Card DNA: Differential Binding of Natural PCR Inhibitors to Guanidine Thiocyanate-Impregnated Filter Paper	Talk	Neonatal Screening Symposium	1996	Boston, Massachusetts
Triad Approach for Detection of Cystic Fibrosis in a Neonatal Screening Program: Identification of an Infant Homozygous for the 2789+G?A Mutation	Talk	Neonatal Screening Symposium	1996	Boston, Massachusetts
Selective Removal of PCR Inhibitors from Guthrie Card Bloodspots: Rapid Detection of Cystic Fibrosis Mutations in Exon 10 and 11	Lecture	North American Regional Neonatal Screening Symposium	1995	Corpus Christi, Texas
Neonatal Cystic Fibrosis Screening: Implications of Apparent Seasonal Variations in Immunoreactive Trypsinogen Concentration	Lecture	North American Regional Neonatal Screening Symposium	1995	Corpus Christi, Texas
Post-Metamorphosis Sequellae of Ni 2+, Co 2+, and Cd 2+ in Xenopus Laevis Assayed by a Modification of the Frog Embryo Teratogenesis Assay Xenopus (FETAX)	Lecture	International Conference on Nickel Metabolism and Toxicology	1992	Sudbury, Ontario, Canada
Excretion of Nickel into Rat Milk and the Effect of Nickel Chloride on Lactating Rats and Their Suckling Pups	Lecture	Society of Toxicology Annual Meeting	1989
Thermoregulatory Impairment in Nickel-Treated Rats	Talk	International Conference on Nickel Metabolism and Toxicology	1988	Espoo, Finland
Biological Reactivity of Nickel Oxides and Related Compounds	Lecture	International Conference on Nickel Metabolism and Toxicology	1988	Espoo, Finland
Nickel Absorption and Elimination in Human Volunteers	Talk	Second Nordic Symposium, World Health Organization	1987	Copenhagen, Denmark
Nickel Concentrations in Body Fluids of Healthy Adults and Hemodialysis Patients in Sudbury, Ontario, Canada	Talk	Second Nordic Symposium, World Health Organization	1987	Copenhagen, Denmark
Cobalt, Chromium, and Nickel Concentrations in Body Fluids of Patients with Porous-Coated Co/Cr Prostheses	Talk		1987	Odense, Denmark
Serum Nickel Concentrations in Patients with Iatrogenic Exposures to Nickel	Talk	American Chemical Society	1985	Miami, Florida

Title or Abstract

Type

Sponsor/Event

Date/Year

Location

Consolidation and Automation: A Safer Environment

Lecture

Beckman Coulter Symposia

2004

White Plains, New York

Laboratory Redesign with Automation: An Ongoing Process

Lecture

Beckman Coulter Symposia

2003

White Plains, New York

Laboratory Redesign with Automation: An Ongoing Process

Lecture

Beckman Coulter Symposia

2003

Boston, Massachusetts

Consolidation and Automation in a Small Hospital Laboratory

Lecture

Beckman Coulter Symposia

2002

White Plains, New York

Consolidation and Automation in a Small Hospital Laboratory

Lecture

Beckman Coulter Symposia

2002

Philadelphia, Pennsylvania

Consolidation and Automation in a Small Hospital Laboratory

Lecture

Beckman Coulter Symposia

2002

Waltham, Massachusetts

Decisions for Laboratory Redesign with Automation

Lecture

American Society for Clinical Laboratory Science

2002

Hartford, Connecticut

Newborn Screening for Cystic Fibrosis

Lecture

Assciation of Public Health Laboratories

2001

Washington, DC

Detection of Cystic Fibrosis in a 24 Week Old Infant: Application of Neonatal Screening in Premature Populations

Lecture

National Neonatal Screening Symposium

1998

San Diego, California

Newborn Screening for Cystic Fibrosis: Early Detection of Infants with Non-?F508 Mutations

Lecture

National Neonatal Screening Symposium

1998

San Diego, California

Detection of Cystic Fibrosis in a 24 Week-Old Infant: Application of Neonatal Screening in Premature Populations

Talk

Neonatal Screening Symposium

1998

San Diego, California

Newborn Screening for Cystic Fibrosis: Early Detection of Infants with Non-?F508 Mutations

Talk

National Neonatal Screening Symposium

1998

San Diego, California

Amplification of Guthrie Card DNA: Differential Binding of Natural PCR Inhibitors to Guanidine Thiocyanate-Impregnated Filter Paper

Lecture

3rd International Neonatal Screening Symposium

1996

Boston, Massachusetts

Triad Approach for Detection of Cystic Fibrosis in a Neonatal Screening Program: Identification of an Infant Homozygous for the 2789+G?A Mutation

Lecture

International Neonatal Screening Symposium

1996

Boston, Massachusetts

Amplification of Guthrie Card DNA: Differential Binding of Natural PCR Inhibitors to Guanidine Thiocyanate-Impregnated Filter Paper

Talk

Neonatal Screening Symposium

1996

Boston, Massachusetts

Triad Approach for Detection of Cystic Fibrosis in a Neonatal Screening Program: Identification of an Infant Homozygous for the 2789+G?A Mutation

Talk

Neonatal Screening Symposium

1996

Boston, Massachusetts

Selective Removal of PCR Inhibitors from Guthrie Card Bloodspots: Rapid Detection of Cystic Fibrosis Mutations in Exon 10 and 11

Lecture

North American Regional Neonatal Screening Symposium

1995

Corpus Christi, Texas

Neonatal Cystic Fibrosis Screening: Implications of Apparent Seasonal Variations in Immunoreactive Trypsinogen Concentration

Lecture

North American Regional Neonatal Screening Symposium

1995

Corpus Christi, Texas

Post-Metamorphosis Sequellae of Ni 2+, Co 2+, and Cd 2+ in Xenopus Laevis Assayed by a Modification of the Frog Embryo Teratogenesis Assay Xenopus (FETAX)

Lecture

International Conference on Nickel Metabolism and Toxicology

1992

Sudbury, Ontario, Canada

Excretion of Nickel into Rat Milk and the Effect of Nickel Chloride on Lactating Rats and Their Suckling Pups

Lecture

Society of Toxicology Annual Meeting

1989

Thermoregulatory Impairment in Nickel-Treated Rats

Talk

International Conference on Nickel Metabolism and Toxicology

1988

Espoo, Finland

Biological Reactivity of Nickel Oxides and Related Compounds

Lecture

International Conference on Nickel Metabolism and Toxicology

1988

Espoo, Finland

Nickel Absorption and Elimination in Human Volunteers

Talk

Second Nordic Symposium, World Health Organization

1987

Copenhagen, Denmark

Nickel Concentrations in Body Fluids of Healthy Adults and Hemodialysis Patients in Sudbury, Ontario, Canada

Talk

Second Nordic Symposium, World Health Organization

1987

Copenhagen, Denmark

Cobalt, Chromium, and Nickel Concentrations in Body Fluids of Patients with Porous-Coated Co/Cr Prostheses

Talk

1987

Odense, Denmark

Serum Nickel Concentrations in Patients with Iatrogenic Exposures to Nickel

Talk

American Chemical Society

1985

Miami, Florida