Faculty Directory › UConn Health

Glenn T. Konopaske, M.D.

Associate Professor of Psychiatry
Medical Director, Intensive Outpatient Program

NPI Number: 1386613354
Academic Office Location: Psychiatry UConn Health 263 Farmington Avenue Farmington, CT 06030-1410
Phone:	860-679-1105
Website(s):	Psychiatry Huntington's Disease

Overview
Education & Training
Clinical Interests
Committees & Organizations
Publications

Dr. Konopaske went to medical school and completed his residency in Psychiatry at the University of Connecticut. He then completed a research fellowship in Translational Neuroscience at the University of Pittsburgh. During his fellowship, Dr. Konopaske studied the neurobiology of schizophrenia. Dr. Konopaske then joined the staff of McLean Hospital in Belmont, MA where he was a psychiatrist on the Psychotic Disorders Unit. He also conducted NIMH-funded research into the neurobiology of schizophrenia and bipolar disorder. Dr. Konopaske returned to UConn Health in 2015.

Education

Degree	Institution	Major
B.S.	Union College	Biology and Classics
M.D.	UConn School of Medicine	Medicine

Degree

Institution

Major

B.S.

Union College

Biology and Classics

M.D.

UConn School of Medicine

Medicine

Post-Graduate Training

Training	Institution	Specialty
Residency	UConn School of Medicine	Psychiatry (Chief Resident, Psychiatry, Outpatient Services 2002-2003)
Fellowship	Western Psychiatric Institute and Clinic	Postdoctoral Fellow, Translational Neuroscience
Certificate in Applied Biostatistics	Harvard Medical School	Certificate in Applied Biostatistics. Rigorous year-long training course in applied biostatistics and the use of STATA software package.

Training

Institution

Specialty

Residency

UConn School of Medicine

Psychiatry (Chief Resident, Psychiatry, Outpatient Services 2002-2003)

Fellowship

Western Psychiatric Institute and Clinic

Postdoctoral Fellow, Translational Neuroscience

Certificate in Applied Biostatistics

Harvard Medical School

Certificate in Applied Biostatistics. Rigorous year-long training course in applied biostatistics and the use of STATA software package.

Awards

Name of Award/Honor	Awarding Organization
Support of Resident Education Award	University of Connecticut General Adult Psychiatry Residency
Young Investigator Award	National Alliance for Research on Schizophrenia and Depression
Maria Lorenz Pope Fellowship	Harvard Medical School
Award for Excellence in Scholarship	UConn Health Center Department of Psychiatry
David Goldberg, M.D. Award for Outstanding Scholarship in Psychotherapy	Connecticut Psychiatric Society

Name of Award/Honor

Awarding Organization

Support of Resident Education Award

University of Connecticut General Adult Psychiatry Residency

Young Investigator Award

National Alliance for Research on Schizophrenia and Depression

Maria Lorenz Pope Fellowship

Harvard Medical School

Award for Excellence in Scholarship

UConn Health Center Department of Psychiatry

David Goldberg, M.D. Award for Outstanding Scholarship in Psychotherapy

Connecticut Psychiatric Society

Dr. Konopaske’s clinical interests include the treatment of patients with bipolar disorder.

Name & Description	Category	Role	Type	Scope	Start Year	End Year
Society for Biological Psychiatry	Professional/Scientific Organization	Member	External	National	2015
American Psychiatric Association	Professional/Scientific Organization	Member	External	National	1999

Name & Description

Journal Articles

Clinical evidence that a dysregulated master neural network modulator may aid in diagnosing schizophrenia.
Nomoto, Munetaka; Konopaske, Glenn T; Yamashita, Naoya; Aoki, Reina; Jitsuki-Takahashi, Aoi; Nakamura, Haruko; Makihara, Hiroko; Saito, Mari; Saigusa, Yusuke; Nakamura, Fumio; Watanabe, Keisuke; Baba, Toshihiko; Benes, Francine M; Tobe, Brian T D; Pernia, Cameron D; Coyle, Joseph T; Sidman, Richard L; Hirayasu, Yoshio; Snyder, Evan Y; Goshima, Yoshio Proceedings of the National Academy of Sciences of the United States of America 2021 Aug;118(31):
Dysbindin-1 contributes to prefrontal cortical dendritic arbor pathology in schizophrenia.
Konopaske, Glenn T; Balu, Darrick T; Presti, Kendall T; Chan, Grace; Benes, Francine M; Coyle, Joseph T Schizophrenia research 2018 May;201270-277
Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.
Tobe, Brian T D; Crain, Andrew M; Winquist, Alicia M; Calabrese, Barbara; Makihara, Hiroko; Zhao, Wen-Ning; Lalonde, Jasmin; Nakamura, Haruko; Konopaske, Glenn; Sidor, Michelle; Pernia, Cameron D; Yamashita, Naoya; Wada, Moyuka; Inoue, Yuuka; Nakamura, Fumio; Sheridan, Steven D; Logan, Ryan W; Brandel, Michael; Wu, Dongmei; Hunsberger, Joshua; Dorsett, Laurel; Duerr, Cordulla; Basa, Ranor C B; McCarthy, Michael J; Udeshi, Namrata D; Mertins, Philipp; Carr, Steven A; Rouleau, Guy A; Mastrangelo, Lina; Li, Jianxue; Gutierrez, Gustavo J; Brill, Laurence M; Venizelos, Nikolaos; Chen, Guang; Nye, Jeffrey S; Manji, Husseini; Price, Jeffrey H; McClung, Colleen A; Akiskal, Hagop S; Alda, Martin; Chuang, De-Maw M; Coyle, Joseph T; Liu, Yang; Teng, Yang D; Ohshima, Toshio; Mikoshiba, Katsuhiko; Sidman, Richard L; Halpain, Shelley; Haggarty, Stephen J; Goshima, Yoshio; Snyder, Evan Y Proceedings of the National Academy of Sciences of the United States of America 2017 May;114E4462-E4471
Glutamatergic Dysfunction in Schizophrenia Evaluated With Magnetic Resonance Spectroscopy.
Coyle, Joseph T; Konopaske, Glenn JAMA psychiatry 2016 Jun;73(7):649-50
Altered prefrontal cortical MARCKS and PPP1R9A mRNA expression in schizophrenia and bipolar disorder.
Konopaske, Glenn T; Subburaju, Sivan; Coyle, Joseph T; Benes, Francine M Schizophrenia research 2015 May;164(1-3):100-8
In vivo magnetic resonance studies reveal neuroanatomical and neurochemical abnormalities in the serine racemase knockout mouse model of schizophrenia.
Puhl, Matthew D; Mintzopoulos, Dionyssios; Jensen, J Eric; Gillis, Timothy E; Konopaske, Glenn T; Kaufman, Marc J; Coyle, Joseph T Neurobiology of disease 2015 Jan;73269-74
Prefrontal cortical dendritic spine pathology in schizophrenia and bipolar disorder.
Konopaske, Glenn T; Lange, Nicholas; Coyle, Joseph T; Benes, Francine M JAMA psychiatry 2014 Dec;71(12):1323-31
Time-dependent effects of haloperidol on glutamine and GABA homeostasis and astrocyte activity in the rat brain.
Konopaske, Glenn T; Bolo, Nicolas R; Basu, Alo C; Renshaw, Perry F; Coyle, Joseph T Psychopharmacology 2013 Nov;230(1):57-67
Catatonia in psychotic patients: clinical features and treatment response.
England, Mary L; Ongür, Dost; Konopaske, Glenn T; Karmacharya, Rakesh The Journal of neuropsychiatry and clinical neurosciences 2011 Jan;23(2):223-6
Effect of chronic antipsychotic exposure on astrocyte and oligodendrocyte numbers in macaque monkeys.
Konopaske, Glenn T; Dorph-Petersen, Karl-Anton; Sweet, Robert A; Pierri, Joseph N; Zhang, Wei; Sampson, Allan R; Lewis, David A Biological psychiatry 2008 Apr;63(8):759-65
Effect of chronic exposure to antipsychotic medication on cell numbers in the parietal cortex of macaque monkeys.
Konopaske, Glenn T; Dorph-Petersen, Karl-Anton; Pierri, Joseph N; Wu, Qiang; Sampson, Allan R; Lewis, David A Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007 Jun;32(6):1216-23
Regional specificity of chandelier neuron axon terminal alterations in schizophrenia.
Konopaske, G T; Sweet, R A; Wu, Q; Sampson, A; Lewis, D A Neuroscience 2006 Jan;138(1):189-96
Interferon-induced growth arrest is mediated by membrane structural changes.
Guha, A; Mason, R P; Primorac, D; Konopaske, G; Miller, J; Sinha, P; Tulenko, T N; Hand, A Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1997 Nov;17(11):701-6

Book Chapters

Schizophrenia
Konopaske, Glenn Coyle, Joseph Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders 2014 Dec;639-653

Other

Possible compensatory mechanisms for glutamatergic disconnection found in the auditory cortex in schizophrenia.
Konopaske, Glenn T; Coyle, Joseph T Biological psychiatry 2015 Jun;77(11):923-4

Reviews

Glutamatergic synaptic dysregulation in schizophrenia: therapeutic implications.
Coyle, Joseph T; Basu, Alo; Benneyworth, Michael; Balu, Darrick; Konopaske, Glenn Handbook of experimental pharmacology 2012 Jan;(213):267-95