Faculty Directory › UConn Health

Chia-Ling Kuo, PhD

Associate Professor
The Cato T. Laurencin Institute for Regenerative Engineering
Department of Public Health Sciences, UConn Health
Co-Leader, UConn Pepper Center Data Resource Core

Academic Office Location: UConn Health 195 Farmington Avenue Farmington, CT 06032
Email:	kuo@uchc.edu
Website(s):	Decoding Aging Lab

Overview
Education & Training
Committees & Organizations
Publications

Welcome to Decoding Aging Lab: Biomarkers of Aging & Drug Repurposing

https://willowy-fox-d15af2.netlify.app

I am a biostatistician by training, with a research focus on aging, particularly biomarkers of aging and drug repurposing. As an NIH-funded investigator, I have an established track record of research funding and publications. My work has investigated genes and biomarkers associated with aging, including APOE, SH2B3, and telomere length.

My research focuses on aging biomarker development and applications. In parallel, I investigate the potential of repurposing FDA-approved drugs to target fundamental biological processes of aging and promote healthy longevity.

My research draws extensively on data from the UK Biobank and U.S.-based population cohorts. I welcome opportunities for collaboration to broaden the scope and impact of my research, particularly through interdisciplinary partnerships and access to additional population-based cohorts.

Selected Publications

https://pubmed.ncbi.nlm.nih.gov/?term=%28Chia-Ling+Kuo%5BAuthor%5D%29+AND+%28UConn%5BAffiliation%5D%29&sort=date

Zhao S, Kuo CL, Lenze EJ, Wetherell JL, Haynes L, El-Ahmad P, Fortinsky R, Kuchel G, Harris T, Diniz BS. A Deep-Learning Based Biomarker of Systemic Cellular Senescence Burden to Predict Mortality and Health Outcomes. Aging Cell. 2026 Oct;25(10):e70737. doi: 10.1111/acel.70737. PMID: 42791602; PMCID: PMC13615172.

Kuo CL, Liu P, Drouard G, Vuoksimaa E, Kaprio J, Ollikainen M, Chen Z, Pilling LC, Atkins JL, Fortinsky RH, Kuchel GA, Diniz BS. A proteomic signature of healthspan. Proc Natl Acad Sci U S A. 2025 Jun 10;122(23):e2414086122. doi: 10.1073/pnas.2414086122. Epub 2025 Jun 6. Erratum in: Proc Natl Acad Sci U S A. 2025 Aug 19;122(33):e2520058122. doi: 10.1073/pnas.2520058122. PMID: 40478878; PMCID: PMC12168021.

Kuo CL, Chen Z, Liu P, Pilling LC, Atkins JL, Fortinsky RH, Kuchel GA, Diniz BS. Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. Aging Cell. 2024 Aug;23(8):e14195. doi: 10.1111/acel.14195. Epub 2024 May 15. PMID: 38747160; PMCID: PMC11320350.

Diniz BS, Chen Z, Steffens DC, Pilling L, Nikolova Y, Clifford K, Fortinsky RH, Kuchel GA, Kuo CL. Proteogenomic signature of Alzheimer's disease and related dementia risk in individuals with major depressive disorder. Nat Ment Health. 2025 Aug;3(8):879-888. doi: 10.1038/s44220-025-00460-0. Epub 2025 Jul 14. PMID: 40823340; PMCID: PMC12356225.

Diniz BS, Zhao S, Drouard G, Vuoksimaa E, Ollikainen M, Lenze EJ, Xu M, Fortinsky RH, Kuchel GA, Kaprio J, Kuo CL. Biological Aging Acceleration in Major Depressive Disorder: A Multi-Omics Analysis. Aging Cell. 2025 Dec 4:e70310. doi: 10.1111/acel.70310. Epub ahead of print. PMID: 41342072.

Liu R, Xiang M, Pilling LC, Melzer D, Wang L, Manning KJ, Steffens DC, Bowden J, Fortinsky RH, Kuchel GA, Rhee TG, Diniz BS, Kuo CL. Mid-life leukocyte telomere length and dementia risk: An observational and mendelian randomization study of 435,046 UK Biobank participants. Aging Cell. 2023 Jul;22(7):e13808. doi: 10.1111/acel.13808. Epub 2023 May 30. PMID: 37254630; PMCID: PMC10352557.

Education

Degree	Institution	Major
BBA	National Chengchi University	Statistics
MS	National Taiwan University	Biostatistics, Statistical Genetics
PhD	University of Pittsburgh	Biostatistics, Statistical Genetics

Degree

Institution

Major

BBA

National Chengchi University

Statistics

National Taiwan University

Biostatistics, Statistical Genetics

PhD

University of Pittsburgh

Biostatistics, Statistical Genetics

Post-Graduate Training

Training	Institution	Specialty
Postdoctoral	National Institute of Environmental Health Sciences (NIEHS)	Research Fellow

Training

Institution

Specialty

Postdoctoral

National Institute of Environmental Health Sciences (NIEHS)

Research Fellow

Awards

Name of Award/Honor	Awarding Organization
Accredited Professional Statistician (2014-present)	American Statistical Association

Name of Award/Honor

Awarding Organization

Accredited Professional Statistician (2014-present)

American Statistical Association

Name & Description	Category	Role	Type	Scope	Start Year
Nature Medicine	Editorial Board	Statistical Advisor	External	International	2026
NIH - ASG	Study Section	Ad Hoc Reviewer	External	National	2026
NIH - CDBA	Study Section	Ad Hoc Reviewer	External	National	2026
Journal of Applied Gerontology	Editorial Board	Statistical Advisor	External	International	2022
Journal of Racial and Ethnic Health Disparities	Editorial Board	Statistical Reviewer	UConn Health	International	2017

Name & Description

Journal Articles

Factors Associated With Treatment Time of Conventional Orthodontic-Orthognathic Surgery Patients in a University Postgraduate Program: A Retrospective Cohort Study.
Florentine, Catherine; Van, Vivian; Shreiteh, Mohammed; Kuo, Chia-Ling; Zhong, Kelin; Uribe, Flavio; Shafer, David Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2026 Oct;
A Deep-Learning Based Biomarker of Systemic Cellular Senescence Burden to Predict Mortality and Health Outcomes.
Zhao, Shangshu; Kuo, Chia-Ling; Lenze, Eric J; Wetherell, Julie L; Haynes, Laura; El-Ahmad, Perla; Fortinsky, Richard; Kuchel, George; Harris, Trevor; Diniz, Breno S Aging Cell. 2026 Oct;25(10):e70737
Impact of reducing aligners' wear schedule from 7-days to 3-days on the predictability of tooth movement and treatment efficiency: a randomized controlled trial.
Brown, Alexandra; Rifai, Maya; Saadatmand, Kiana; Zhong, Kelin; Kuo, Chia-Ling; Uribe, Flavio; Dolce, Calogero; Abu Arqub, Sarah Clinical oral investigations 2026 Aug;30(9):
Red Blood Cell Distribution Width Is Associated With Functional Outcomes Following Surgery for Hip Fracture.
Kositsawat, Jatupol; Zhao, Shangshu; Kuchel, George A; Fortinsky, Richard H; Barry, Lisa C; Binder, Ellen F; Magaziner, Jay S; Doré, Peter M; Kuo, Chia-Ling Journal of the American Geriatrics Society. 2026 Jul;
Heterogeneity in Aging: Exploring Grip Strength Variability in Population-Based Age-Sex Cohorts.
Fortinsky, Richard H; Barry, Lisa C; Zavez, Katherine; Kuo, Chia-Ling; Zhao, Shangshu; Harel, Ofer; Kuchel, George A The Journals of Gerontology. Series A, Biological sciences and medical sciences 2026 Jul;
Rising trends in dermatology publications using large-scale databases.
Tessier-Kay, Madeleine; Zhou, Albert E; Zhong, Kelin; Kuo, Chia-Ling; Sloan, Brett; Grant-Kels, Jane M; Feng, Hao Clinics in dermatology 2026 May;
Testosterone therapy effects adipose distribution in older females post hip-fracture: The STEP-HI study.
Earp, Jacob E; Zhao, Shangshu; Xu, Furong; Kuo, Chia-Ling; Bartley, Jenna M; Fortinsky, Richard H; Kositsawat, Jatupol; Rehbein, Carlos O; Binder, Ellen F; Stevens-Lapsley, Jennifer; Kuchel, George A Obesity Pillars. 2026 Mar;17100247
'OrthoQA' semantic search and question-answering tool for orthodontic education.
Arqub, Sarah Abu; Zhao, Qian; Akolkar, Prapti; Al-Moghrabi, Dalya; Kuo, Chia-Ling; Zhong, Kelin; Alomair, Dur; Adel, Mohamed; Zhang, Ying Journal of dentistry 2026 Feb;106590
Influence of different malocclusion traits on overall orthodontic treatment duration.
Abu Arqub, Sarah; Gandhi, Vaibhav; AlOmari, Eyad; Kuo, Chia-Ling; Upadhyay, Madhur; Yadav, Sumit The Angle orthodontist 2026 Feb;
Effect of Location of Minilaparotomy for Morcellation at the time of Myomectomy and Hysterectomy on Postoperative Pain.
Kowalski, Leigh; Buchman, Madison; Bian, Helen; Zhong, Kelin; Kuo, Chia-Ling; Newmark, Alexis; Luciano, Danielle; Ulrich, Amanda Journal of minimally invasive gynecology 2026 Jan;
Patient satisfaction and clinical outcomes of digital dentures fabricated in a predoctoral dental clinic: An up to 2-year retrospective analysis.
Touloumi, Foteini; Vafa, Rameen P; Motlagh, Naeem M; Taylor, Thomas D; Kuo, Chia-Ling; Bidra, Avinash S Journal of prosthodontics : official journal of the American College of Prosthodontists 2026 Jan;
VA-ECMO in high-risk pulmonary embolism: outcomes and role as bridge to recovery.
Arvind, Shreya; Wagner, Hilary; Kuo, Chia-Ling; Zhong, Kelin; Gluck, Jason; Ingrassia, Joseph Resuscitation plus 2026 Jan;27101196
The nonlinear U-shaped association between vitamin D deficiency and biological aging acceleration is enhanced in individuals with higher inflammation levels.
Kositsawat, Jatupol; Kuchel, George A; Zhong, Kelin; Zhao, Shangshu; Fortinsky, Richard H; Kuo, Chia-Ling. The journals of gerontology. Series A, Biological sciences and medical sciences. 2025 Dec;
Biological Aging Acceleration in Major Depressive Disorder: A Multi-Omics Analysis.
Diniz, Breno Satler; Zhao, Shangshu; Drouard, Gabin; Vuoksimaa, Eero; Ollikainen, Miina; Lenze, Eric J; Xu, Ming; Fortinsky, Richard H; Kuchel, George A; Kaprio, Jaakko; Kuo, Chia-Ling Aging Cell. 2025 Dec;e70310
Angiographic Characteristics and Associated Risk Factors of Premature Coronary Artery Disease among South Asians: A Systematic Review.
Passey, Siddhant; Jha, Jagriti; Iverson, Marissa; Zhong, Kelin; Kuo, Chia-Ling; Arora, Sameer; Qamar, Arman; Beohar, Nirat The American journal of cardiology 2025 Sep;2591-11
Micro-computed tomography assessment of regional and overall accuracy of thermoformed retainers and intraoral scanners.
Luna Montes, Maria; Zakhary, Mina Atef; Cobos, Santiago F; Kuo, Chia-Ling; Zhong, Kelin; Abu Arqub, Sarah; Uribe, Flavio American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2025 Sep;
Survival outcomes of implants placed in the pterygoid region: A retrospective study of up to 9 years.
Bidra, Avinash S; Sim, Paul; Kuo, Chia-Ling Journal of prosthodontics : official journal of the American College of Prosthodontists 2025 Sep;
Proteogenomic signature of Alzheimer's disease and related dementia risk in individuals with major depressive disorder.
Diniz, Breno Satler; Chen, Zhiduo; Steffens, David C; Pilling, Luke; Nikolova, Yuliya; Clifford, Kevan; Fortinsky, Richard H; Kuchel, George A; Kuo, Chia-Ling Nature. Mental Health. 2025 Aug;3(8):879-888
Advancing Age and Risk From the Elevated Atherogenic Index: Triglyceride (TG) to High-Density Cholesterol (HDL-C) Ratio.
Kumar, Manish; Zhao, Shangshu; Robinson, Peter; Kuchel, George A; Fortinsky, Richard H; Orkaby, Ariela R; Alexander, Karen P; Thompson, Paul D; Batsis, John A; Kuo, Chia-Ling. Journal of the American Geriatrics Society. 2025 Jun;
A proteomic signature of healthspan.
Kuo, Chia-Ling; Liu, Peiran; Drouard, Gabin; Vuoksimaa, Eero; Kaprio, Jaakko; Ollikainen, Miina; Chen, Zhiduo; Pilling, Luke C; Atkins, Janice L; Fortinsky, Richard H; Kuchel, George A; Diniz, Breno S Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2025 Jun;122(23):e2414086122
Protein Associations With Alcohol Consumption and Genetic Risk for Alcohol-Related Sociomedical Conditions.
Drouard, Gabin; Palviainen, Teemu; Kuo, Chia-Ling; Diniz, Breno S; Wang, Xiaoling; Ollikainen, Miina; Latvala, Antti; Kaprio, Jaakko Addiction biology 2025 Jun;30(6):e70045
Clinical outcomes of conversion prosthesis in immediately loaded implants: A retrospective study.
Migus, Karolina M; Bidra, Avinash S; Kuo, Chia-Ling Journal of prosthodontics : official journal of the American College of Prosthodontists 2025 Jan;
The Influence of Sexual Orientation and Gender Identity on the Otolaryngology Residency Experience.
Jongbloed, Walter M; Newsome, Hillary A; Kashat, Lawrence; Parham, Kourosh; Faucett, Erynne A; Kuo, Chia-Ling; Zhong, Kelin; Kavanagh, Katherine R OTO open 2025 Jan;9(2):e70095
Interactions between vitamin D deficiency and inflammation on diabetes risk: data from 336,500 UK Biobank adults: Short title Vitamin D Deficiency, Inflammation, and Diabetes.
Kositsawat, Jatupol; Zhao, Shangshu; Kuchel, George A; Barry, Lisa C; Fortinsky, Richard H; Kirk, Ben; Duque, Gustavo; Kuo, Chia-Ling The Journal of Nutrition, Health & Aging. 2024 Dec;29(2):100446
Polyploid superficial uroepithelial bladder barrier cells express features of cellular senescence across the lifespan and are insensitive to senolytics.
Al-Naggar, Iman M; Antony, Maria; Baker, Dylan; Wang, Lichao; Godoy, Lucas Da Cunha; Kuo, Chia-Ling; Fraser, Matthew O; Smith, Phillip P; Xu, Ming; Kuchel, George A Aging Cell. 2024 Dec;e14399
Cone beam computed tomography outcomes in patients diagnosed with compromised bone health undergoing dental implant therapy and bone augmentation.
Wilson, Caroline; Taxel, Pamela; Shafer, David; Tadinada, Aditya; Godoy, Lucas da Cunha; Kuo, Chia-Ling; Freilich, Martin The Journal of prosthetic dentistry 2024 Dec;
Diagnostic power of serum creatinine/cystatin C ratio for identifying low MRI-muscle volume and low grip strength: Data from 9,731 to 149,707 UK Biobank older adults.
Kirk, Ben; Kuo, Chia-Ling; Liu, Peiran; Xiang, Meiruo; Zanker, Jesse; Prokopidis, Konstantinos; Sim, Marc; Fortinsky, Richard H; Kuchel, George A; Duque, Gustavo The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Nov;
Age-stratified assessment of orthodontic tooth movement outcomes with clear aligners.
Chaluparambil, Mariamma; Abu Arqub, Sarah; Kuo, Chia-Ling; Godoy, Lucas Da Cunha; Upadhyay, Madhur; Yadav, Sumit Progress in orthodontics 2024 Nov;25(1):43
Positional, morphologic, and volumetric differences in TMJ in unilateral posterior crossbites and controls: A retrospective CBCT study.
Dresner, Rebecca; Mehta, Shivam; Upadhyay, Madhur; El-Bialy, Tarek; Kuo, Chia-Ling; Tadinada, Aditya; Yadav, Sumit International orthodontics 2024 Sep;22(3):100889
Accuracy of full arch scans using the iTero Element 2® intra-oral scanner: A clinical study.
Abu Arqub, Sarah; Hariharan, Amirtha; Banankhah, Sina; Da Cunha Godoy, Lucas; Liu, Perian; Kuo, Chia-Ling; Uribe, Flavio Journal of orthodontics 2024 Aug;14653125241268755
Intermittent clearance of p21-highly-expressing cells extends lifespan and confers sustained benefits to health and physical function.
Wang, Binsheng; Wang, Lichao; Gasek, Nathan S; Kuo, Chia-Ling; Nie, Jia; Kim, Taewan; Yan, Pengyi; Zhu, Junyu; Torrance, Blake L; Zhou, Yueying; Flores, Lisa C; Allen, Colton; Andrade, Allison M; Guo, Chun; Cohn, Rachel L; Jellison, Evan R; Bartley, Jenna M; Kuchel, George A; Li, Sheng; Pirtskhalava, Tamar; Tchkonia, Tamar; Yadav, Sumit; Haynes, Laura; Kirkland, James L; Ikeno, Yuji; Xu, Ming Cell Metabolism. 2024 Aug;36(8):1795-1805.e6
Comparative assessment of the clinical outcomes of clear aligners compared to fixed appliance in class II malocclusion.
Irsheid, Ruwa; Godoy, Lucas Da Cunha; Kuo, Chia-Ling; Metz, John; Dolce, Calogero; Abu Arqub, Sarah Clinical oral investigations 2024 Jul;28(8):445
Short- and long-term effects of conventional and miniscrew-assisted rapid palatal expansion on hard tissues using voxel-based superimposition of serial cone-beam computed tomography scans.
Empson, Isaac; Del Santo, Marinho; Kuo, Chia-Ling; Vich, Manuel Lagravere; Liu, Dawei; Yadav, Sumit; Mehta, Shivam American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2024 Jul;
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults.
Kuo, Chia-Ling; Chen, Zhiduo; Liu, Peiran; Pilling, Luke C; Atkins, Janice L; Fortinsky, Richard H; Kuchel, George A; Diniz, Breno S Aging Cell. 2024 May;e14195
Perceptions and utilization of tele-orthodontics: a survey of the members of the American Association of Orthodontists.
Abu Arqub, Sarah; Al-Moghrabi, Dalya; Kuo, Chia-Ling; Da Cunha Godoy, Lucas; Uribe, Flavio Progress in orthodontics 2024 May;25(1):16
Retrospective evaluation of the success rate and factors associated with the stability of alveolar ridge orthodontic miniscrews: Pilot study.
Abu Arqub, Sarah; Greene, Renee; Greene, Sara; Laing, Kolbe; Kuo, Chia-Ling; Godoy, Lucas Da Cunha; Uribe, Flavio Journal of the World federation of orthodontists 2024 Apr;
Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone.
Türkmen, Deniz; Bowden, Jack; Masoli, Jane A H; Delgado, João; Kuo, Chia-Ling; Melzer, David; Pilling, Luke C The pharmacogenomics journal 2024 Apr;24(3):12
Leukocyte telomere length is associated with MRI-thigh fat-free muscle volume: data from 16 356 UK Biobank adults.
Kirk, Ben; Kuo, Chia-Ling; Liu, Peiran; Xiang, Meiruo; Earp, Jacob E; Kositsawat, Jatupol; Kuchel, George A; Duque, Gustavo Journal of Cachexia, Sarcopenia and Muscle 2024 Mar;
Three-dimensional Assessment of Temporomandibular Joint Volume, and Condylar and Glenoid-fossa Morphology: A Cone-beam Computed Tomography Study.
Mehta, Shivam; Gandhi, Vaibhav; Patel, Apexa; Chen, Po-Jung; Lin, Meng-Hsuan; Kuo, Chia-Ling; Tadinada, Aditya; Yadav, Sumit Contemporary clinical dentistry 2023 Dec;14(4):256-264
Prevalence of likely retro-odontoid pseudotumor in patients receiving dental CBCT examinations.
Fryc, Gosia Anna; Godoy, Lucas da Cunha; Kuo, Chia-Ling; Lurie, Alan G Oral surgery, oral medicine, oral pathology and oral radiology 2023 Nov;
Relationship between baseline plasma p-tau181 and longitudinal changes in cognition and structural brain measures in a cohort of cognitively unimpaired older adults.
Pais, Marcos V; Kuo, Chia-Ling; Ances, Beau M; Wetherell, Julie Loebach; Lenze, Eric J; Diniz, Breno S Alzheimer's & dementia (Amsterdam, Netherlands) 2023 Nov;15(4):e12487
Accelerated aging mediates the associations of unhealthy lifestyles with cardiovascular disease, cancer, and mortality.
Li, Xueqin; Cao, Xingqi; Zhang, Jingyun; Fu, Jinjing; Mohedaner, Mayila; Danzengzhuoga; Sun, Xiaoyi; Yang, Gan; Yang, Zhenqing; Kuo, Chia-Ling; Chen, Xi; Cohen, Alan A; Liu, Zuyun Journal of the American Geriatrics Society 2023 Oct;
Characterizing orthodontic tooth movement in real time using dental monitoring scans: A pilot study.
Arqub, Sarah Abu; Nedjat-Haiem, Michael; Einbinder, Max; Azami, Niloufar; Kuo, Chia-Ling; Hariharan, Amirtha; Uribe, Flavio Orthodontics & craniofacial research 2023 Sep;
A Survey on Cone-beam Computed Tomography Usage Among Endodontists in the United States.
Duong, Christie; Zhu, Qiang; Aseltine, Robert H; Kuo, Chia-Ling; da Cunha Godoy, Lucas; Kaufman, Blythe Journal of endodontics 2023 Aug;
Comparison of electronic versus mechanical torque-limiting devices for dental implants: An in vitro study.
Faraj, Mohaad A; Bidra, Avinash S; Taylor, Thomas D; Kuo, Chia-Ling Journal of prosthodontics : official journal of the American College of Prosthodontists 2023 Aug;
Does physical activity moderate the association between shorter leukocyte telomere length and incident coronary heart disease? Data from 54,180 UK Biobank participants.
Xiang, Meiruo; Pilling, Luke C; Melzer, David; Kirk, Ben; Duque, Gustavo; Liu, Rui; Kuchel, George A; Wood, Andrew R; Metcalf, Brad; Diniz, Breno S; Hillsdon, Melvyn; Kuo, Chia-Ling GeroScience 2023 Aug;
Assessment of clear aligner accuracy of 2 clear aligners systems.
Harandi, Mahdi Taebi; Abu Arqub, Sarah; Warren, Emma; Kuo, Chia-Ling; Da Cunha Godoy, Lucas; Mehta, Shivam; Feldman, Jonathan; Upadhyay, Madhur; Yadav, Sumit American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2023 Jul;
Association between Residential Exposure to Air Pollution and Incident Coronary Heart Disease Is Not Mediated by Leukocyte Telomere Length: A UK Biobank Study.
Kuo, Chia-Ling; Liu, Rui; Godoy, Lucas da Cunha; Pilling, Luke C; Fortinsky, Richard H; Brugge, Doug Toxics 2023 May;11(6):
Association between Residential Exposure to Air Pollution and Incident Coronary Heart Disease Is Not Mediated by Leukocyte Telomere Length: A UK Biobank Study
Kuo, Chia-Ling; Liu, Rui.; da Cunha Godoy, Lucas; Pilling, Luke C.; Fortinsky, Richard H.; Brugge, Doug Toxics 2023 May;11(489):
Rhinologist Use of Antibiotics With Nasal Packing for Epistaxis.
Mallen, Jonathan Ross; Aasen, Davis M; Vuncannon, Jackson Ross; Kuo, Chia-Ling; Mu, Jinjian; Tessema, Belachew; Brown, Seth M American journal of rhinology & allergy 2023 May;19458924231176394
Alpha Feto-protein Expression Trends for Screening Early Hepatocellular Carcinoma
Turshudzhyan A, Godoy LD, Kuo CL, Wu GY Gene Expression 2023 Apr;22(2):109-114
Very Low and High Levels of Vitamin D Are Associated with Shorter Leukocyte Telomere Length in 148,321 UK Biobank Participants.
Kuo, Chia-Ling; Kirk, Ben; Xiang, Meiruo; Pilling, Luke C; Kuchel, George A; Kremer, Richard; Duque, Gustavo. Nutrients. 2023 Mar;15(6):
Insight into clear aligner therapy protocols and preferences among members of the American Association of Orthodontists in the United States and Canada.
Abu-Arqub, Sarah; Ahmida, Ahmad; Da Cunha Godoy, Lucas; Kuo, Chia-Ling; Upadhyay, Madhur; Yadav, Sumit The Angle orthodontist 2023 Mar;
Tolerability of nasal and oral povidone-iodine antisepsis for in-office procedures.
Frank, Samantha; Ibrahim, Bishoy; Feng, Ruby; Bidra, Avinash; Lafreniere, Denis; Kuo, Chia-Ling; Da Cunha Godoy, Lucas; Falcone, Todd E Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery 2023 Mar;
Dental implant and bone augmentation treatment in bone-compromised patients: Oral health-related quality of life outcomes.
Leonard, Jonathan F; Taxel, Pamela; Kuo, Chia-Ling; Da Cunha Godoy, Lucas; Freilich, Martin The Journal of prosthetic dentistry 2023 Feb;
Comparable Skeletal and Dental Movements Achieved Using Conventional and Surgery-First Techniques in Class III Patients.
Florentine, Catherine; Kimberly, Anna; Mehta, Shivam; Kuo, Chia-Ling; Uribe, Flavio; Lottinger, Christy Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2022 Nov;80(11):1747-1756
Assessment of the occlusal outcomes in patients treated with orthognathic surgery and clear aligners.
Kwon, Taewoo; Alshehri, Abdulrahman; Palo, Ledjo; Kuo, Chia-Ling; Mu, Jinjian; Blanck, Nyle; Nanda, Ravindra; Arqub, Sarah Abu; Uribe, Flavio Orthodontics & craniofacial research 2022 Oct;
NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health
SenNet Consortium Nat Aging 2022 Oct;21090–1100
Calcium-channel blockers: Clinical outcome associations with reported pharmacogenetics variants in 32 000 patients.
Türkmen, Deniz; Masoli, Jane A H; Delgado, João; Kuo, Chia-Ling; Bowden, Jack; Melzer, David; Pilling, Luke C British journal of clinical pharmacology 2022 Sep;89(2):853-864
Survival and failure rate of lower lingual bonded retainers: A retrospective cohort evaluation.
Arqub, Sarah Abu; Bashir, Rehana; Obeng, Kaimen; Godoy, Lucas Da Cunha; Kuo, Chia-Ling; Upadhyay, Madhur; Yadav, Sumit Orthodontics & craniofacial research 2022 Aug;
Associations between leukocyte telomere length and osteosarcopenia in 20,400 adults aged 60 years and over: Data from the UK Biobank.
Kirk, Ben; Kuo, Chia-Ling; Xiang, Meiruo; Duque, Gustavo Bone 2022 Aug;161116425
Association between initial complexity, frequency of refinements, treatment duration, and outcome in Invisalign orthodontic treatment.
Arqub, Sarah Abu; Banankhah, Sina; Sharma, Ravish; Da Cunha Godoy, Lucas; Kuo, Chia-Ling; Ahmed, Maram; Alfardan, Mariam; Uribe, Flavio American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2022 Jul;
Life course traumas and cardiovascular disease-The mediating role of accelerated aging.
Cao, Xingqi; Zhang, Jingyun; Ma, Chao; Li, Xueqin; Kuo, Chia-Ling; Levine, Morgan E; Hu, Guoqing; Allore, Heather; Chen, Xi; Wu, Xifeng; Liu, Zuyun Annals of the New York Academy of Sciences 2022 Jun;
Evaluation of interproximal reduction in individual teeth, and full arch assessment in clear aligner therapy: digital planning versus 3D model analysis after reduction.
Hariharan, Amirtha; Arqub, Sarah Abu; Gandhi, Vaibhav; Da Cunha Godoy, Lucas; Kuo, Chia-Ling; Uribe, Flavio Progress in orthodontics 2022 Mar;23(1):9
Statin treatment effectiveness and the SLCO1B1*5 reduced function genotype: Long-term outcomes in women and men.
Türkmen, Deniz; Masoli, Jane A H; Kuo, Chia-Ling; Bowden, Jack; Melzer, David; Pilling, Luke C British Journal of Clinical Pharmacology 2022 Jan;
Demand Ischemia as a Predictor of Mortality in Older Patients With Delirium.
Kumar, Manish; Patil, Shivaraj; Godoy, Lucas Da Cunha; Kuo, Chia-Ling; Swede, Helen; Kuchel, George A; Chen, Kai Frontiers in cardiovascular medicine. 2022 Jan;9917252
GCM2 Variants in Familial and Multiglandular Primary Hyperparathyroidism.
Vincze, Sarah; Peters, Nicholas V; Kuo, Chia-Ling; Brown, Taylor C; Korah, Reju; Murtha, Timothy D; Bellizzi, Justin; Riccardi, Aaliyah; Parham, Kourosh; Carling, Tobias; Costa-Guda, Jessica; Arnold, Andrew The Journal of Clinical Endocrinology and Metabolism 2021 Dec;
Analysis of CYP2C19 genetic variants with ischaemic events in UK patients prescribed clopidogrel in primary care: a retrospective cohort study.
Pilling, Luke C; Türkmen, Deniz; Fullalove, Hannah; Atkins, Janice L; Delgado, Joao; Kuo, Chia-Ling; Kuchel, George A; Ferrucci, Luigi; Bowden, Jack; Masoli, Jane A H; Melzer, David BMJ open 2021 Dec;11(12):e053905
Long-term effects of conventional and miniscrew-assisted rapid palatal expansion on root resorption.
Mehta, Shivam; Arqub, Sarah Abu; Vich, Manuel Lagravere; Kuo, Chia-Ling; Tadinada, Aditya; Upadhyay, Madhur; Yadav, Sumit American Journal of Orthodontics and Dentofacial Orthopedics 2021 Dec;161(3):e235-e249
Antidiabetic Effects of the Senolytic Agent Dasatinib.
Salaami, Omid; Kuo, Chia-Ling; Drake, Matthew T; Kuchel, George A; Kirkland, James L; Pignolo, Robert J. Mayo Clinic Proceedings 2021 Oct;96(12):3021-3029
The Triangulation WIthin a STudy (TWIST) framework for causal inference within pharmacogenetic research.
Bowden, Jack; Pilling, Luke C; Türkmen, Deniz; Kuo, Chia-Ling; Melzer, David PLoS genetics 2021 Sep;17(9):e1009783
Examining the Development of Operative Autonomy in Vascular Surgery Training and When Trainees and Program Directors Agree and Disagree.
Huynh, Cindy; Da Cunha Godoy, Lucas; Kuo, Chia-Ling; Smeds, Matthew; Amankwah, Kwame S Annals of vascular surgery Surgery 2021 Jul;74(1):1-10
Network Topology of Biological Aging and Geroscience-Guided Approaches to COVID-19
Landay, Alan; Bartley, Jenna; Banerjee, Dishary; Hargis, Geneva; Haynes, Laura; Keshavarzian, Ali; Kuo, Chia-Ling; Kwon, Oh Sung; Li, Sheng; Li, Shuzhao; Oh, Julia; Ozbolat, Ibrahim Tarik; Ucar, Duygu; Xu, Ming; Yao, Xudong; Unutmaz, Derya; Kuchel, George A. Front Aging 2021 Jul;
Joint Corticosteroid Injection Associated With Higher Physical Therapy Compliance in Knee Osteoarthritis.
Mantovani Cardoso, Eduardo; Feterman Jimenez, Dominique; Kuo, Chia-Ling; Jacob, Jason Cureus 2021 Jul;13(7):e16403
APOE e4 genotypes increase risk of delirium during COVID-19 related hospitalizations: evidence from a large United Kingdom cohort.
Kuo, Chia-Ling; Pilling, Luke C; Atkins, Janice L; Fortinsky, Richard H; Kuchel, George A; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2021 Jun;
Patients' perceptions of orthodontic treatment experiences during COVID-19: a cross-sectional study.
Arqub, Sarah Abu; Voldman, Rebecca; Ahmida, Ahmad; Kuo, Chia-Ling; Godoy, Lucas Da Cunha; Nasrawi, Yousef; Al-Khateeb, Susan N; Uribe, Flavio Progress in orthodontics 2021 Jun;22(1):17
Genetic associations for two biological age measures point to distinct aging phenotypes.
Kuo, Chia-Ling; Pilling, Luke C; Liu, Zuyun; Atkins, Janice L; Levine, Morgan E Aging cell 2021 May;e13376
Esophageal dysmotility and lung disease in patients with systemic sclerosis: is there a possible association or correlation? A retrospective chart review.
Kuchipudi, Navya; Kishore, Shweta; Kuo, Chia-Ling; Lakshminarayanan, Santhanam; Mandhadi, Ranadeep Rheumatology International 2021 May;
Aging changes in bladder HCN are associated with increasing heterogeneity of adrenergic/mucosal influence on detrusor control in the mouse.
Hardy, Cara C; Al-Naggar, Iman M; Kuo, Chia-Ling; Kuchel, George A; Smith, Phillip P The journals of gerontology. Series A, Biological sciences and medical sciences 2021 Mar;
Biological Aging Predicts Vulnerability to COVID-19 Severity in UK Biobank Participants.
Kuo, Chia-Ling; Pilling, Luke C; Atkins, Janice L; Masoli, Jane A H; Delgado, João; Tignanelli, Christopher; Kuchel, George A; Melzer, David; Beckman, Kenneth B; Levine, Morgan E The journals of gerontology. Series A, Biological sciences and medical sciences 2021 Mar;
The Influence of Age and Facial Expression (Eye Open/Closed) On Maxillary Dental and Gingival Display.
Bidra, Avinash S; Persenaire, Mitchell; Kuo, Chia-Ling Journal of prosthodontics : official journal of the American College of Prosthodontists 2021 Feb;
The effect of the local administration of biological substances on the rate of orthodontic tooth movement: a systematic review of human studies.
Arqub, Sarah Abu; Gandhi, Vaibhav; Iverson, Marissa G; Ahmed, Maram; Kuo, Chia-Ling; Mu, Jinjian; Dutra, Eliane; Uribe, Flavio Progress in orthodontics 2021 Feb;22(1):5
Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.
Jones, Garan; Trajanoska, Katerina; Santanasto, Adam J; Stringa, Najada; Kuo, Chia-Ling; Atkins, Janice L; Lewis, Joshua R; Duong, ThuyVy; Hong, Shengjun; Biggs, Mary L; Luan, Jian'an; Sarnowski, Chloe; Lunetta, Kathryn L; Tanaka, Toshiko; Wojczynski, Mary K; Cvejkus, Ryan; Nethander, Maria; Ghasemi, Sahar; Yang, Jingyun; Zillikens, M Carola; Walter, Stefan; Sicinski, Kamil; Kague, Erika; Ackert-Bicknell, Cheryl L; Arking, Dan E; Windham, B Gwen; Boerwinkle, Eric; Grove, Megan L; Graff, Misa; Spira, Dominik; Demuth, Ilja; van der Velde, Nathalie; de Groot, Lisette C P G M; Psaty, Bruce M; Odden, Michelle C; Fohner, Alison E; Langenberg, Claudia; Wareham, Nicholas J; Bandinelli, Stefania; van Schoor, Natasja M; Huisman, Martijn; Tan, Qihua; Zmuda, Joseph; Mellström, Dan; Karlsson, Magnus; Bennett, David A; Buchman, Aron S; De Jager, Philip L; Uitterlinden, Andre G; Völker, Uwe; Kocher, Thomas; Teumer, Alexander; Rodriguéz-Mañas, Leocadio; García, Francisco J; Carnicero, José A; Herd, Pamela; Bertram, Lars; Ohlsson, Claes; Murabito, Joanne M; Melzer, David; Kuchel, George A; Ferrucci, Luigi; Karasik, David; Rivadeneira, Fernando; Kiel, Douglas P; Pilling, Luke C Nature Communications. 2021 Jan;12(1):654
Hemochromatosis Mutations, Brain Iron Imaging, and Dementia in the UK Biobank Cohort.
Atkins, Janice L; Pilling, Luke C; Heales, Christine J; Savage, Sharon; Kuo, Chia-Ling; Kuchel, George A; Steffens, David C; Melzer, David Journal of Alzheimer's disease : JAD 2021 Jan;79(3):1203-1211
Smoking cessation and counseling: A mixed methods study of pediatricians and parents.
Simoneau, Tregony; Hollenbach, Jessica P; Langton, Christine R; Kuo, Chia-Ling; Cloutier, Michelle M PloS one 2021 Jan;16(2):e0246231
Long-term effects of mini-screw-assisted rapid palatal expansion on airway.
Mehta, Shivam; Wang, Dennis; Kuo, Chia-Ling; Mu, Jinjian; Vich, Manuel Lagravere; Allareddy, Veerasathpurush; Tadinada, Aditya; Yadav, Sumit The Angle orthodontist 2020 Dec;
Effect of positional errors on the accuracy of cervical vertebrae maturation assessment using CBCT and lateral cephalograms.
Mehta, Shivam; Dresner, Rebecca; Gandhi, Vaibhav; Chen, Po-Jung; Allareddy, Veerasathpurush; Kuo, Chia-Ling; Mu, Jinjian; Yadav, Sumit Journal of the World federation of orthodontists 2020 Dec;9(4):146-154
Association of Hemochromatosis HFE p.C282Y Homozygosity With Hepatic Malignancy.
Atkins, Janice L; Pilling, Luke C; Masoli, Jane A H; Kuo, Chia-Ling; Shearman, Jeremy D; Adams, Paul C; Melzer, David JAMA 2020 Nov;324(20):2048-2057
Evaluation of open bite closure using clear aligners: a retrospective study.
Harris, Kayla; Ojima, Kenji; Dan, Chisato; Upadhyay, Madhur; Alshehri, Abdulrahman; Kuo, Chia-Ling; Mu, Jinjian; Uribe, Flavio; Nanda, Ravindra Progress in orthodontics 2020 Aug;21(1):23
Utility of Smartphone Telemedical Consultations for Peritonsillar Abscess Diagnosis and Triage.
Mallen, Jonathan R; Shah, Manan Udayan; Drake, Ryan; Kreicher, Kathryn; Falcone, Todd; Karter, Nicholas; Schoem, Scott; Grindle, Christopher; Wolfe, Stephen; Kuo, Chia-Ling; Mu, Jinjian; Lotterman, Seth; Bonaiuto, Gregory JAMA otolaryngology-- head & neck surgery 2020 Aug;
Quantifying tinnitus suppression in cochlear implantation using tinnitus interval-limited tracking.
Mallen, Jonathan R; Chiu, Jerlon; Marquis, Hillary; Ottochian, Amanda; Perez, Erin; Kuo, Chia-Ling; Otto, Steve; Ryan, Tessa; Roberts, Daniel S The Laryngoscope 2020 Aug;130(8):2047-2052
Preexisting Comorbidities Predicting COVID-19 and Mortality in the UK Biobank Community Cohort.
Atkins, Janice L; Masoli, Jane A H; Delgado, Joao; Pilling, Luke C; Kuo, Chia-Ling; Kuchel, George A; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Jul;
Biomarkers of orthodontic tooth movement with fixed appliances and vibration appliance therapy: a pilot study.
Reiss, Stacey; Chouinard, Marie Claude; Frias Landa, Dasha; Nanda, Ravindra; Chandhoke, Taranpreet; Sobue, Takanori; Allareddy, Veerasathpurush; Kuo, Chia-Ling; Mu, Jinjian; Uribe, Flavio European journal of orthodontics 2020 Jun;
ApoE e2 and aging-related outcomes in 379,000 UK Biobank participants.
Kuo, Chia-Ling; Pilling, Luke C; Atkins, Janice L; Kuchel, George A; Melzer, David Aging 2020 Jun;12
Opioid Use and Rate of Nicotine Metabolism among Pregnant Smokers.
Oncken, Cheryl; Mead, Erin L; Dornelas, Ellen A; Kuo, Chia-Ling; Sankey, Heather Z; Kranzler, Henry R; Thurlow, Sheila Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2020 May;22(6):1046-1050
Comparison of external apical root resorption with clear aligners and pre-adjusted edgewise appliances in non-extraction cases: a systematic review and meta-analysis.
Gandhi, Vaibhav; Mehta, Shivam; Gauthier, Marissa; Mu, Jijian; Kuo, Chia-Ling; Nanda, Ravindra; Yadav, Sumit European journal of orthodontics 2020 Feb;
Influence of type of radiograph and levels of experience and training on reproducibility of the cervical vertebral maturation method.
Khajah, Anfal; Tadinada, Aditya; Allareddy, Veerasathpurush; Kuo, Chia-Ling; Nanda, Ravindra; Uribe, Flavio American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2020 Feb;157(2):228-239
GRK2 enforces androgen receptor dependence in the prostate and prostate tumors.
Adler, Adam J; Mittal, Payal; Hagymasi, Adam T; Menoret, Antoine; Shen, Chen; Agliano, Federica; Wright, Kyle T; Grady, James J; Kuo, Chia-Ling; Ballesteros, Enrique; Claffey, Kevin P; Vella, Anthony T Oncogene 2020 Jan;
A 16-Year Study on Incidence and Progression of Diseased Sphenoethmoidal (Onodi) Cell.
Huang, Ethan I; Kuo, Chia-Ling; Lee, Li-Wen BioMed research international 2020 Jan;20202410415
An analysis of anterior mandibular anatomy by using cone beam computed tomography: A study of 225 mandibular images.
Wright, Roberta A; Bidra, Avinash S; Kuo, Chia-Ling The Journal of prosthetic dentistry 2019 Oct;
Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants.
Kuo, Chia-Ling; Pilling, Luke C; Kuchel, George A; Ferrucci, Luigi; Melzer, David Aging Cell. 2019 Aug;e13017
Relationship between Radiographic Misfit and Clinical Outcomes in Immediately Loaded Complete-Arch Fixed Implant-Supported Prostheses in Edentulous Patients.
Slauch, Robert W; Bidra, Avinash S; Wolfinger, Glenn J; Kuo, Chia-Ling Journal of prosthodontics : official journal of the American College of Prosthodontists 2019 Aug;
The Longevity Associated Sh2b3 (LNK) Genetic Variant: Selected Aging Phenotypes in 379,758 Subjects.
Kuo, Chia-Ling; Joaquim, Micaella; Kuchel, George A; Ferrucci, Luigi; Harries, Lorna; Pilling, Luke C; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2019 Aug;
Cornstarch Requirements of the Adult Glycogen Storage Disease Ia Population: A Retrospective Review.
Dahlberg, K R; Ferrecchia, I A; Dambska-Williams, M; Resler, T E; Ross, K M; Butler, G L; Kuo, C L; Ryan, P; Weinstein, D A Journal of inherited metabolic disease 2019 Aug;
A school nurse-led asthma program reduces absences: Evaluation of Easy Breathing for Schools.
Simoneau, Tregony; Langton, Christine R; Kuo, Chia-Ling; Marrero, Jing; Gherlone, Nicole; Cloutier, Michelle M; Hollenbach, Jessica P Academic pediatrics 2019 Jul;
Interaction between Vitamin D and Interleukin 6 on Slow Gait Speed: 6-year Follow-up Data of Older Adults from InCHIANTI.
Kositsawat, Jatupol; Kuo, Chia-Ling; Barry, Lisa; Melzer, David; Bandinelli, Stefania; Ferrucci, Luigi; Wu, Rong; Kuchel, George A The journals of gerontology. Series A, Biological sciences and medical sciences 2019 Jul;
Hair cortisol, perceived stress, and social support in mother-child dyads living in an urban neighborhood.
Hollenbach, Jessica P; Kuo, Chia-Ling; Mu, Jinjian; Gerrard, Meg; Gherlone, Nicole; Sylvester, Franklin; Ojukwu, Mary; Cloutier, Michelle M Stress (Amsterdam, Netherlands) 2019 Apr;1-8
Sarcopenia and variation in the Human Leukocyte Antigen complex.
Jones, Garan; Pilling, Luke C; Kuo, Chia-Ling; Kuchel, George; Ferrucci, Luigi; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2019 Feb;
Hereditary Hemochromatosis Associations with Frailty, Sarcopenia and Chronic Pain: Evidence from 200,975 Older UK Biobank Participants.
Tamosauskaite, Jone; Atkins, Janice L; Pilling, Luke C; Kuo, Chia-Ling; Kuchel, George A; Ferrucci, Luigi; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2019 Feb;74(3):337-342
Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank.
Pilling, Luke C; Tamosauskaite, Jone; Jones, Garan; Wood, Andrew R; Jones, Lindsay; Kuo, Chai-Ling; Kuchel, George A; Ferrucci, Luigi; Melzer, David BMJ (Clinical research ed.) 2019 Jan;364k5222
Analysis of activating GCM2 sequence variants in sporadic parathyroid adenomas
Riccardi A, Aspir T, Shen L, Kuo CL, Brown TC, Korah R, Murtha TD, Bellizzi J, Parham K, Carling T, Costa-Guda J, Arnold A J Clin Endocrinol Metab 2019 Jan;1041948-52
Evaluation of a guideline directed medical therapy titration program in patients with heart failure with reduced ejection fraction.
Balakumaran, Kathir; Patil, Aadhar; Marsh, Shannon; Ingrassia, Joseph; Kuo, Chia-Ling; Jacoby, Daniel Louis; Arora, Sabeena; Soucier, Richard International journal of cardiology. Heart & vasculature 2018 Nov;221-5
Training for Failure: A Simulation Program for Emergency Medicine Residents to Improve Communication Skills in Service Recovery.
Frallicciardi, Alise; Lotterman, Seth; Ledford, Matthew; Prenovitz, Ilana; Meter, Rochelle Van; Kuo, Chia-Ling; Nowicki, Thomas; Fuller, Robert AEM education and training 2018 Oct;2(4):277-287
Outcomes of an early childhood obesity prevention program in a low-income community: a pilot, randomized trial.
Cloutier, M M; Wiley, J F; Kuo, C-L; Cornelius, T; Wang, Z; Gorin, A A Pediatric obesity 2018 Aug;13677-685
Bone Regenerative Engineering Using a Protein Kinase A-Specific Cyclic AMP Analogue Administered for Short Term
Okechukwu Clinton Ifegwu; Guleid Awale; Ho Man Kan; Komal Rajpura; Edward O’Neill; Chia-Ling Kuo; Kevin W.-H. Lo Regenerative Engineering and Translational Medicine 2018 Jul;4(4):206-215
Endoscopic Features of Mucous Cap Polyps: A Way to Predict Serrated Polyps.
Moy Brian T, Forouhar Faripour, Kuo Chia-Ling,Devers, Thomas J Clinical endoscopy 2018 Apr;51368-374
Opioid Prescribing Patterns among Otolaryngologists.
Schwartz, Marissa A; Naples, James G; Kuo, Chia-Ling; Falcone, Todd E Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2018 Feb;158854-859
Which orthodontic appliance is best for oral hygiene? A randomized clinical trial.
Chhibber, Aditya; Agarwal, Sachin; Yadav, Sumit; Kuo, Chia-Ling; Upadhyay, Madhur American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2018 Feb;153(2):175-183
Biodegradable Piezoelectric Force Sensor.
Curry, Eli J; Ke, Kai; Chorsi, Meysam T; Wrobel, Kinga S; Miller, Albert N; Patel, Avi; Kim, Insoo; Feng, Jianlin; Yue, Lixia; Wu, Qian; Kuo, Chia-Ling; Lo, Kevin W-H; Laurencin, Cato T; Ilies, Horea; Purohit, Prashant K; Nguyen, Thanh D Proceedings of the National Academy of Sciences of the United States of America 2018 Jan;115909-914
Unconditional or Conditional Logistic Regression Model for Age-Matched Case-Control Data?
Kuo, Chia-Ling; Duan, Yinghui; Grady, James Frontiers in public health 2018 Jan;657
Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.
Pilling, Luke C; Kuo, Chia-Ling; Sicinski, Kamil; Tamosauskaite, Jone; Kuchel, George A; Harries, Lorna W; Herd, Pamela; Wallace, Robert; Ferrucci, Luigi; Melzer, David Aging 2017 Dec;9(12):2504-2520
Modified Z-palatoplasty with one-layer closure in one-stage multilevel surgery for severe obstructive sleep apnea.
Huang, Ethan I; Kuo, Chia-Ling; Chou, Yu-Ting; Lin, Yu-Ching; Huang, Shu-Yi Auris, nasus, larynx 2017 Oct;45791-795
Racial/Ethnic Disparities in Morbidity and Mortality for Preterm Neonates Admitted to a Tertiary Neonatal Intensive Care Unit.
Townsel, Courtney; Keller, Rebecca; Kuo, Chia-Ling; Campbell, Winston A; Hussain, Naveed Journal of racial and ethnic health disparities 2017 Oct;5867-874
The more you test, the more you find: The smallest P-values become increasingly enriched with real findings as more tests are conducted.
Vsevolozhskaya, Olga A; Kuo, Chia-Ling; Ruiz, Gabriel; Diatchenko, Luda; Zaykin, Dmitri V Genetic epidemiology 2017 Sep;41726-743
Does the Difference in Fascial Closure Technique Affect Post-Operative Pain?
Lyapis, Anna; Ulrich, Amanda; LaMonica, Rachel; Kuo, Chia-Ling; Kaye, Leak; Luciano, Danielle Journal of minimally invasive gynecology 2017 Jul;241190-1194
Differences in Lip Support with and without Labial Flanges in a Maxillary Edentulous Population - Part 3: Unblinded and Discriminatory Subjective Analysis.
Bidra, Avinash S; Nguyen, Viensuong; Manzotti, Anna; Kuo, Chia-Ling Journal of prosthodontics : official journal of the American College of Prosthodontists 2017 May;2722-28
Correlates of Electronic Cigarettes Use Before and During Pregnancy.
Oncken, Cheryl; Ricci, Karen A; Kuo, Chia-Ling; Dornelas, Ellen; Kranzler, Henry R; Sankey, Heather Z Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2017 May;19(5):585-590
Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.
Pilling, Luke C; Atkins, Janice L; Duff, Michael O; Beaumont, Robin N; Jones, Samuel E; Tyrrell, Jessica; Kuo, Chia-Ling; Ruth, Katherine S; Tuke, Marcus A; Yaghootkar, Hanieh; Wood, Andrew R; Murray, Anna; Weedon, Michael N; Harries, Lorna W; Kuchel, George A; Ferrucci, Luigi; Frayling, Timothy M; Melzer, David PloS one 2017 Jan;12(9):e0185083
Ranking question designs and analysis methods
Hoag, Jessica R; Kuo, Chia-Ling Journal of Medical Statistics and Informatics 2016 May;6(4):
Cost Implications for Subsequent Perinatal Outcomes After IVF Stratified by Number of Embryos Transferred: A Five Year Analysis of Vermont Data.
Carpinello, Olivia J; Casson, Peter R; Kuo, Chia-Ling; Raj, Renju S; Sills, E Scott; Jones, Christopher A Applied health economics and health policy 2016 Mar;14387-95
Prospective cohort pilot study of 2-visit CAD/CAM monolithic complete dentures and implant-retained overdentures: Clinical and patient-centered outcomes.
Bidra, Avinash S; Farrell, Kimberly; Burnham, David; Dhingra, Ajay; Taylor, Thomas D; Kuo, Chia-Ling The Journal of prosthetic dentistry 2016 Jan;115578-586.e1
Evaluation of the donor cell contribution in rhBMP-2 mediated bone formation with chitosan thermogels using fluorescent protein reporter mice.
Gohil, Shalini V; Kuo, Chia-Ling; Adams, Douglas J; Maye, Peter; Rowe, David W; Nair, Lakshmi S Journal of biomedical materials research. Part A 2015 Dec;104928-41
Neck recurrence and mortality in esthesioneuroblastoma: Implications for management of the N0 neck.
Naples, James G; Spiro, Jeffrey; Tessema, Belachew; Kuwada, Clinton; Kuo, Chia-Ling; Brown, Seth M The Laryngoscope 2015 Nov;1261373-9
Assessing the Probability that a Finding Is Genuine for Large-Scale Genetic Association Studies.
Kuo, Chia-Ling; Vsevolozhskaya, Olga A; Zaykin, Dmitri V PloS one 2015 Jan;10(5):e0124107
The ranking probability approach and its usage in design and analysis of large-scale studies.
Kuo, Chia-Ling; Zaykin, Dmitri PloS one 2013 Jan;8(12):e83079
Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies.
McKay, Gareth J; Patterson, Chris C; Chakravarthy, Usha; Dasari, Shilpa; Klaver, Caroline C; Vingerling, Johannes R; Ho, Lintje; de Jong, Paulus T V M; Fletcher, Astrid E; Young, Ian S; Seland, Johan H; Rahu, Mati; Soubrane, Gisele; Tomazzoli, Laura; Topouzis, Fotis; Vioque, Jesus; Hingorani, Aroon D; Sofat, Reecha; Dean, Michael; Sawitzke, Julie; Seddon, Johanna M; Peter, Inga; Webster, Andrew R; Moore, Anthony T; Yates, John R W; Cipriani, Valentina; Fritsche, Lars G; Weber, Bernhard H F; Keilhauer, Claudia N; Lotery, Andrew J; Ennis, Sarah; Klein, Michael L; Francis, Peter J; Stambolian, Dwight; Orlin, Anton; Gorin, Michael B; Weeks, Daniel E; Kuo, Chia-Ling; Swaroop, Anand; Othman, Mohammad; Kanda, Atsuhiro; Chen, Wei; Abecasis, Goncalo R; Wright, Alan F; Hayward, Caroline; Baird, Paul N; Guymer, Robyn H; Attia, John; Thakkinstian, Ammarin; Silvestri, Giuliana Human mutation 2011 Dec;32(12):1407-16
Novel rank-based approaches for discovery and replication in genome-wide association studies.
Kuo, Chia-Ling; Zaykin, Dmitri V Genetics 2011 Sep;189(1):329-40
Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people.
McKay, Gareth J; Silvestri, Giuliana; Chakravarthy, Usha; Dasari, Shilpa; Fritsche, Lars G; Weber, Bernhard H; Keilhauer, Claudia N; Klein, Michael L; Francis, Peter J; Klaver, Caroline C; Vingerling, Johannes R; Ho, Lintje; De Jong, Paulus T D V; Dean, Michael; Sawitzke, Julie; Baird, Paul N; Guymer, Robyn H; Stambolian, Dwight; Orlin, Anton; Seddon, Johanna M; Peter, Inga; Wright, Alan F; Hayward, Caroline; Lotery, Andrew J; Ennis, Sarah; Gorin, Michael B; Weeks, Daniel E; Kuo, Chia-Ling; Hingorani, Aroon D; Sofat, Reecha; Cipriani, Valentina; Swaroop, Anand; Othman, Mohammad; Kanda, Atsuhiro; Chen, Wei; Abecasis, Goncalo R; Yates, John R; Webster, Andrew R; Moore, Anthony T; Seland, Johan H; Rahu, Mati; Soubrane, Gisele; Tomazzoli, Laura; Topouzis, Fotis; Vioque, Jesus; Young, Ian S; Fletcher, Astrid E; Patterson, Chris C American journal of epidemiology 2011 Jun;173(12):1357-64
What's the best statistic for a simple test of genetic association in a case-control study?
Kuo, Chia-Ling; Feingold, Eleanor Genetic epidemiology 2010 Apr;34(3):246-53
Robust score statistics for QTL linkage analysis.
Bhattacharjee, Samsiddhi; Kuo, Chia-Ling; Mukhopadhyay, Nandita; Brock, Guy N; Weeks, Daniel E; Feingold, Eleanor American journal of human genetics 2008 Mar;82(3):567-82
An insight into clear aligner's therapy protocols and preferences among members of the American Association of Orthodontists in the United States and Canada
Arqub SA, Ahmida A, Da Cunha Godoy L, Kuo CL, Upadhyay M, Yadav S The Angle Orthodontist

Book Chapters

Bidirectional Relationships between COVID-19 and Frailty in Older Adults
Kuo CL, Coll PC, Kuchel GA Frailty: A Multidisciplinary Approach to Assessment, Management, and Prevention 2023 Aug;
Normal and non-normal data simulations for the evaluation of two-sample location tests
Hoag, Jessica R; Kuo, Chia-Ling Monte Carlo Simulation-Based Statistical Modeling 2017 Feb;
Discovering multilocus associations with complex pain phenotypes
Kuo, Chia-Ling, Diatchenko, Luda; Zaykin, Dmitri V Genetics of Human Pain Perception: Basic to Translational Science 2013 Nov;

Case Reports

The Relationship between Food Security and Gestational Diabetes among Pregnant Women.
Cooper, Shontreal; Graham, Maura; Kuo, Chia-Ling; Khangura, Raminder; Schmidt, Adrienne; Bakaysa, Stephanie AJP reports 2022 Jul;12(3):e131-e138

Letters

Authors' response.
Harandi, Mahdi Taebi; Abu Arqub, Sarah; Warren, Emma K; Kuo, Chia-Ling; Da Cunha Godoy, Lucas; Mehta, Shivam; Feldman, Jonathan; Upadhyay, Madhur; Yadav, Sumit American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2024 Apr;165(4):379
Response to Comment on "ApoE e4e4 genotype and mortality with COVID-19 in UK Biobank" by Kuo et al.
Kuo, Chia-Ling; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Aug;
ApoE e4e4 genotype and mortality with COVID-19 in UK Biobank.
Kuo, Chia-Ling; Pilling, Luke C; Atkins, Janice L; Masoli, Jane A H; Delgado, João; Kuchel, George A; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Jul;
APOE e4 genotype predicts severe COVID-19 in the UK Biobank community cohort.
Kuo, Chia-Ling; Pilling, Luke C; Atkins, Janice L; Masoli, Jane A H; Delgado, João; Kuchel, George A; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2020 May;

Reviews

Premature aging in serious mental illness.
Diniz, Breno S; Fries, Gabriel R; Kuo, Chia-Ling; Xu, Ming; Lenze, Eric J Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2026 Jan;
Comparison of safety and efficacy of ultrasound-accelerated thrombolysis vs. standard catheter-directed thrombolysis for the management of acute pulmonary embolism - a systematic review and meta-analysis.
Passey, Siddhant; Jain, Hritvik; Jha, Jagriti; Zhong, Kelin; Kuo, Chia-Ling; Iverson, Marissa; Patail, Haris; Joshi, Saurabh; Ingrassia, Joseph Journal of thrombosis and thrombolysis 2025 Apr;
Ridge mini-implants, a versatile biomechanical anchorage device whose success is significantly enhanced by splinting: a clinical report.
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