Trained as a medical sociologist, she developed one of the first school based health clinic programs in the U.S., and has devoted her professional work to improving maternal and child health and community based health profession education. She has developed partnerships with many community programs both in the Greater Hartford area and internationally, at the Universities of Peradenyia (Sri Lanka), Antwerp (Belgium), Puerto Rico, and Costa Rica as well as NGOs such as the Haitian Health Foundation, IHCAI (International Health Central American Institute, Costa Rica), and BOCED (Buguruka Orphan and Community Economic Development Tanzania). She has served as President of the International Health Medical Education Consortium (IHMEC) and as a board member of IHCAI and BOCED. She has held leadership roles in the Group on Educational Affairs of the Association of American Medical Colleges, was President of the Connecticut Public Health Association and the Adolescent Health Council, and is Co-Chair of the International Health Committee of the Maternal and Child Health Section of the American Public Health Association.
Professor Lewis's research interests include medical sociology, maternal and child health, community health, and medical education.