UCONN

HEALTH

Photo of Kevin  Lo, Ph.D.

Kevin Lo, Ph.D.

Assistant Professor
UConn Health | Department of Medicine, Endocrinology
UConn Stem Cell Institute
Department of Biomedical Engineering
Institute for Regenerative Engineering (IRE)
Institute of Materials Science (IMS)
Investigator Advocate
UConn | Connecticut Institute for Clinical and Translational Science (CICATS)
Deputy Editor
Journal of Racial and Ethnic Health Disparities
Springer Nature
Academic Office Location:
R1704
UConn Health
400 Farmington Avenue
Farmington, CT 06030-6404
Phone: 860-679-2949
860-679-5576
Email: wlo@uchc.edu
Education
DegreeInstitutionMajor
B.Sc.Hong Kong University of Science and TechnologyBiochemistry
M.Phil.Hong Kong University of Science and TechnologyBiochemistry
Ph.D.Hong Kong University of Science and TechnologyBiochemistry

Post-Graduate Training
TrainingInstitutionSpecialty
FellowshipUniversity of Connecticut Health CenterSupervisor: Dr. Cato T. Laurencin, Department of Orthopaedic Surgery

Project 1: Small Molecule based Musculoskeletal Tissue Engineering The utilization of small molecules for engineering musculoskeletal tissues has been largely overlooked. We envision that this trend is very likely to be reversed as advanced screening technologies have recently generated a large number of novel regenerative small molecule compounds, and advanced tissue engineering scaffolds continue to provide promise for controllable drug delivery to target tissues. We have chosen skeletal tissue as a test bed of small molecule-based regenerative engineering because of the challenge of treating skeletal diseases and injury clinically.


Project 2: Targeted Nanoscale Drug Delivery Vehicle for Bone Diseases.


Project 3: Intracellular drug delivery system utilizing cytoplasmic dynein motor protein.

Accepting new students.

Journal Articles

Book Chapters

  • Cytoplasmic Dynein Function Defined by Subunit Composition. Chapter 15
    Pfister, K.K. and Lo, K.W.-H.: Dyneins: Structure, Biology and Disease 2012 Jan;423-436
  • Biomimetric Matrices for Integrin-mediated Cell Adhesion
    Ashe, K.M., Lee, D.A., Lo, K.W.-H., Nair, L.S., and Laurencin, C.T. (2010) Biologically-Responsive Hybrid Biomaterials: A Reference for Material Scientists and Bioengineers 247-284
  • Calcium Phosphate based Ceramics for Biomedical Application. Biodegradable polymers in clinical use and clinical development.
    Lv, Q., Lo, K.W.-H., Nair, L.S., and Laurencin, C.T. Chapter 14 495-517

Editorials

  • Bone morphogenetic proteins for bone regeneration and their alternatives.
    Laurencin CT and Lo KWH (2013) Curr Pharm Des 19(19):3353

Reviews

Title or AbstractTypeSponsor/EventDate/YearLocation
Cytoplasmic Dynein Associated Peptide-linked Nanoparticles for Non-viral Vector ApplicationsPosterWorld Biomaterials Congress2016Montreal, Canada
Inductive Small Molecule Regeneration: Convergence of Pharmaceutical Sciences and Biomedical Engineering.LectureWallace H. Coulter Foundation Lecture Series.2015Florida International University, Miami, FL,
Osteotropic Nanoscale Drug Delivery System via a Single Aspartic Acid as the Bone-targeting MoietyPosterBMES2015Tampa, FL
Inductive Small Molecule Regeneration: Convergence of Pharmaceutical Sciences and Regenerative EngineeringLectureUniversity of Houston2014Houston, TX
Development of Poly-aspartic Acid Peptide Linked PLGA-based Nanoparticles for Bone TargetingPlenary LectureBMES2014TX
Engineered Bone Tissue Through Short-term Administration of an Osteogenic Small MoleculePosterBMES2014TX