|M.D.||New Jersey Medical School||Medicine|
|Name of Award/Honor||Awarding Organization|
|Elected member, CT Academy of Science and Engineering||CT Academy of Science and Engineering|
|Women in Innovation, Research and Leadership Award||Connecticut Technology Council|
|Arteriosclerosis Thrombosis Vascular Biology Special Recognition Award||American Heart Association|
|Scientist of the Year||Great Minds in STEM|
|Name & Description||Category||Role||Type||Scope||Start Year||End Year|
|HDL Workshop||Professional/Scientific Organization||Leadership||External||International||2018||2020|
|NIH Study section, Clinical and Integrative Cardiovascular Sciences||Study Section||Reviewer||External||National||2018|
|NIH, Anonymization Study||Study Section||Reviewer||External||National||2018|
|American Heart Association, Arteriosclerosis Thrombosis Vascular Biology, Member-at-Large, Nomination Committee||Professional/Scientific Organization||Leadership||External||International||2015||2021|
The Rodriguez-Oquendo lab is studying the genetic link between healthy HDL cholesterol, heart disease, and infertility in women. This work suggests that variations within the SCARB1 gene, connected to HDL levels, are associated with heart disease risk as well as hormonal and fertility problems in women. The goal of the research discoveries is the development of methods to diagnose and, ultimately, treat heart disease and improve a woman’s ability to conceive.
Not accepting students for lab rotations at this time
Lp-PLA2, scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease.
PloS one 2018 Jan;13(10):e0204352
Lymphocyte activation gene 3 and coronary artery disease.
JCI insight 2016 Oct;1(17):e88628
A Novel Anti-Inflammatory Effect for High Density Lipoprotein.
PloS one 2015 Jan;10(12):e0144372
Association of the Lipoprotein Receptor SCARB1 Common Missense Variant rs4238001 with Incident Coronary Heart Disease.
PloS one 2015 Jan;10(5):e0125497
Association of SCARB1 variants with subclinical atherosclerosis and incident cardiovascular disease: the multi-ethnic study of atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2012 Aug;32(8):1991-9
Clinical impact of scavenger receptor class B type I gene polymorphisms on human female fertility.
Human reproduction (Oxford, England) 2011 Jul;26(7):1910-6
Endoscopic localization and tattooing of a proinsulinoma for minimally invasive resection.
Pancreas 2011 Apr;40(3):474-7
Deficiency of scavenger receptor class B type I negatively affects progesterone secretion in human granulosa cells.
Endocrinology 2010 Nov;151(11):5519-27
The impact of luteal phase support on gene expression of extracellular matrix protein and adhesion molecules in the human endometrium during the window of implantation following controlled ovarian stimulation with a GnRH antagonist protocol.
Fertility and sterility 2010 Nov;94(6):2264-71
A synonymous variant in scavenger receptor, class B, type I gene is associated with lower SR-BI protein expression and function.
Atherosclerosis 2010 May;210(1):177-82
Association of scavenger receptor class B type I polymorphisms with subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis.
Circulation. Cardiovascular genetics 2010 Feb;3(1):47-52
Nitric oxide metabolite production in the human preimplantation embryo and successful blastocyst formation.
Fertility and sterility 2009 Apr;91(4 Suppl):1316-8
Scavenger receptor class B type I protein as an independent predictor of high-density lipoprotein cholesterol levels in subjects with hyperalphalipoproteinemia.
The Journal of clinical endocrinology and metabolism 2009 Apr;94(4):1451-7
Expression of scavenger receptor-BI and low-density lipoprotein receptor and differential use of lipoproteins to support early steroidogenesis in luteinizing macaque granulosa cells.
Endocrinology 2009 Feb;150(2):957-65
Control of lipids at baseline in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial.
Preventive cardiology 2009 Jan;12(1):9-18
Aging, androgens, and the metabolic syndrome in a longitudinal study of aging.
The Journal of clinical endocrinology and metabolism 2007 Sep;92(9):3568-72
Efficacy and safety of statin monotherapy in older adults: a meta-analysis.
The journals of gerontology. Series A, Biological sciences and medical sciences 2007 Aug;62(8):879-87
Chronic intermittent hypoxia induces atherosclerosis.
American journal of respiratory and critical care medicine 2007 Jun;175(12):1290-7
Variants in scavenger receptor class B type I gene are associated with HDL cholesterol levels in younger women.
Human heredity 2007 Jan;64(2):107-13
Association of lower plasma estradiol levels and low expression of scavenger receptor class B, type I in infertile women.
Fertility and sterility 2006 May;85(5):1391-7