Photo of Susan H. Tannenbaum, M.D.

Susan H. Tannenbaum, M.D.

Associate Professor, Medicine
Chief, Division of Hematology/Oncology
Academic Office Location:

UConn Health
263 Farmington Avenue
Farmington, CT 06030
Phone: 800-579-7822
860-679-2100
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My clinical and research interests are focused on Breast Cancer Care from prevention, early detection, and treatment to survivorship. My goal is to see all patients at UConn with a breast cancer diagnosis.

At the University of Connecticut, my leadership role has been in developing the Clinical and Translational Breast Program. Although the UConn Breast Service was busy, there was no organized structure. My goal in creating the program and continuing as the medical director, was to develop and offer multidisciplinary treatment planning and interventions to patients, with defined oversight and quality control. I established a weekly Multidisciplinary Breast Tumor Board, with the goals of obtaining uniform reporting and oversight of breast pathology and breast imaging. At these meetings we discuss the diagnosis, additional studies needed, multidisciplinary treatment plans, psychosocial issues, and possibilities of investigator initiated and cooperative group clinical trials.

Creation of a Breast Cancer Research Group as a venue to integrate research in our patient population was something I created in 2005. As the Breast Cancer Research Group developed and the researchers realized they had an effective voice and a connection to the patient, the group has grown and become more active. The objectives of the Breast Program Research Development Plan are to expand research, provide opportunities for all investigators interested in translational breast cancer research and to achieve collective successes.

My previous experience included nine years at the National Institutes of Health as a basic researcher in endothelial cell biology and as a clinician for seven years in a busy private practice in Pasadena California. This has enabled me to live in both clinical and basic science worlds and operate successfully as a Translational Scientist. In accordance with that, my pilot grants as well as my participation with other researchers on their pilot and NIH-sponsored grants is key to our success.

Education
DegreeInstitutionMajor
B.S.Cornell UniversityBiology
M.D.State University of New YorkMedicine

Post-Graduate Training
TrainingInstitutionSpecialty
InternshipBronx Municipal Hospital CenterInternal Medicine
ResidencyBronx Municipal Hospital CenterResident/Chief, Internal Medicine
FellowshipHospital of the University of Pennsylvania Hematology-Oncology

Awards
Name of Award/HonorAwarding Organization
Outstanding Teacher Award for Excellence in Teaching and Mentoring
Superior Merit Rating for Research and Education, 2008
I am the assistant program director and key clinical faculty member for the Hematology Oncology Fellowship program. I am involved in regular teaching of fellow trainees on a regular basis. I act as a clinical research mentor for residents, fellows, graduate students, and medical students. Additionally, I run several clinical conferences for the medical students at UConn.
Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
Chemotherapy Committee Research CommitteeChairUConn HealthUniversity2008
Ethics Committee Education CommitteeCommittee MemberUConn HealthUniversity2007
Medical Board Member Education CommitteeBoard MemberUConn HealthUniversity2006
Compensation Appeals Committee Education CommitteeCommittee MemberUConn HealthUniversity2006
Research Financial Subcommittee OtherCommittee MemberUConn HealthUniversity2005
Quality assurance/Quality improvement, Department of Medicine Research CommitteeCommittee MemberUConn HealthUniversity2005
Scientific Advisory Committee, General Clinical Research Center, UCONN Advisory CommitteeCommittee MemberExternalUniversity2004
Cancer Committee, John Dempsey Hospital Research CommitteeCommittee MemberUConn HealthUniversity20042006
Breast Cancer Research Group, Neag Comprehensive Cancer Center Research CommitteeChairUConn HealthUniversity2004
American Society of HematologyProfessional/Scientific OrganizationNational
American Society of Clinical OncologyProfessional/Scientific OrganizationNational
American Society of Breast DiseasesProfessional/Scientific OrganizationNational
Multiple primarily clinical/translational research projects both investigator initiated and Cooperative Group studies related to improving outcomes in women with breast cancer. These include but are not limited to: novel imaging studies to diagnose and monitor breast cancer treatment, epidemiologic and laboratory diagnostic studies, treatment studies, bone health studies in the setting of anti-estrogen therapies,chemotherapy induced heart toxicity studies. These are collaborative studies with basic scientists and other clinical and translational researchers.

Journal Articles

Abstracts

  • Assessing Tumor Response to Neoadjuvant Chemotherapy using Ultrasound-guided Near Infrared Light.
    Quing Zhu, Patricia DeFusco, Susan Tannenbaum Andrew Ricci, Edward Cronin, Poornima Hegde, Mark Kane, Behnoosh Tavakoli, and Yan Xu. SABCS 2011 Jan;
  • Early Detection of Cardiotoxicity by Advanced Cardiac Imaging and a Novel Biomarker in Breast Cancer Patients Undergoing Chemotherapy.
    Marfatia R, Inyangetor D, Decena K, Kumar S, Alluri N, Yang C, Hager D, Fellows D, Runowicz CR, Kaloudis E, Liang BT, Tannenbaum S, Avelar E SABCS 2011 Jan;
  • Quality improvement analysis of HER2 FISH testing in breast cance in response to the new ASCO/CAP guidelines.
    Fang, M., Thalody, V. Tannenbaum, S. Cancer Res 2009 Jan;69(2):
  • The correlation of tumor vascularity as imaged by near-infrared technology with tissue distribution of angiogenic and growth promoters.
    Tannenbaum, S., Phoenix, K., Hegde, P., Claffey, K Cancer Res 2009 Jan;69
  • Mental and physical stressors in the diagnosis of breast cancer: an analysis of distress and systemic biomarkers in patients referred for biopsy of a suspected breast cancer lesion.
    Tannenbaum, S., Wilson, L., Cruess, D., Kamath, J., Baccaro, N., Phoenix, N., Phoenix, K., Claffey, K. SABCS 2009 Jan;
  • Tumor angiogenesis imaged by optical tomography can accurately diagnose early-stage invasive breast cancers.
    Zhu, Q., Kane,M., Tannenbaum, S., Cronin, E., Hegde, P, Iyers, M., DeFusco,P., Ardeshirpour, Y., Xu, C, BaccaroN., Kurtzman, S. Deckers,P Cancer Res 2009 Jan;
  • Investigation of Symptom Distress, Risk Factors and Biomarkers early in breast cancer diagnosis.
    Kamath, J., Claffey, K., Cruess, D., Bacarro, N., Zhang, W., Wilson, L, Kenefick, A., Iyer, M., Tannenbaum, S. Psycho-Oncology 2008 Jan;
  • Investigation of Symptom Distress, Risk Factors and Biomarkers early in breast cancer diagnosis.
    Kamath, J., Claffey, K., Cruess, D., Bacarro, N., Zhang, W., Wilson, L, Kenefick, A., Iyer, M., Tannenbaum, S. Psycho-Oncology 2008 Jan;
  • Activation of coagulation by TNF isolated limb/liver perfusions.
    Tannenbaum, S., Fraker, D., Alexander,H.R., Arnold, W.S., Merryman, P., and Gralnick, H. Blood 1995 Jan;82285
  • The quantitation of endothelial cell von Willebrand factor as an indicator of angiogenesis.
    Tannenbaum, S., Chao, E., and Gralnick, H Blood 1995 Jan;82(1):149
  • Effects of human fibrosarcoma tumor supernatant on endothelial cells: induction of tissue factor expression and augmented expression of adhesion molecules in response to tumor necrosis factor.
    Arnold, W. S., Tannenbaum,S., Yu,K., Alexander, H.R., And Fraker, D American College of Surgeons Surgical Forum XLV 1994 Jan;
  • The effect of heparin on endothelial cell von Willebrand factor.
    Tannenbaum, S. Chao, E., and Gralnick,H Thromb. Haemost 1993 Jan;691183
  • Pentostatin induces thrombocytopenia and platelet dysfunction during continous infusion.
    Tannenbaum, S., Alms, A., Goad, K., Pluda, J., and Parker, R Blood 1991 Jan;78(1):146
  • Willebrand factor in differentiated endothelial cells.
    9. Tannenbaum, S., Chao, E., and Gralnick, H Blood 1991 Jan;78149
  • Further characterization of heparin-enhanced von Wilebrand factor production in umbilical vein endothelial cells.
    Tannenbaum, S. and Gralnick, H Blood 1990 Jan;76(1):522
  • Stimulated release of von Willebrand factor from umbilical vein endothelial cells is enhanced by heparin.
    Tannenbaum, S. and Gralnick, H Blood 1989 Jan;74(1):40
  • Gamma interferon inhibits stimulated release of von Willebrand factor from endothelial cells.
    Tannenbaum, S. and Gralnick, H Blood 1988 Jan;72(1):376
  • Phorbol esters alter the normal distribution of endothelial cell matrix von Willebrand factor.
    Tannenbaum, S., Rick, M., and Gralnick, H Blood 1987 Jan;70409
  • Aggregated IgG stimulates the fibrinolytic inhibitory activity of human endothelial cells.
    Tannenbaum, S., Barnathan, E., Vanderkeyl, H., Kuo, A., Murray, S., and Cines, D Blood 1986 Jan;68(1):119
  • Immune endothelial cell injury in heparin associated thrombocytopenia.
    Cines, D., and Tannenbaum,S Clin. Res 1985 Jan;33336
  • Production of tissue factor by human endothelial cells following immune injury.
    Tannenbaum, S., and Cines, D Blood 1984 Jan;64(1):268

Conference Papers

Reviews

Title or AbstractTypeSponsor/EventDate/YearLocation
Mental and Physical Stressors in the Diagnosis of Breast Cancer: An Analysis of Distress and Systemic Biomarkers in Patients Referred for Biopsy of a Suspected Breast Cancer LesionPosterSan Antonio Breast Cancer Symposium2009
The Correlation of Tumor Vascularity as Imaged by Near-infrared Technology with Tissue Distribution of angiogenic and Growth PromotersPosterSan Antonio Breast Cancer Symposium2008
Noninvasive Monitoring of Neoadjuvant Chemotherapy using Optical Tomography with Ultrasound Localization: Initial ExperiencePosterSan Antonio Breast Cancer Symposium2007
Utilization of Near-infrared Optical Tomography with Ultrasound Localization for Predicting Angiogenic Tumor Responses to Primary Systemic TherapyPosterSan Antonio Breast Cancer Symposium2005