Photo of Roger S. Thrall, Ph.D.

Roger S. Thrall, Ph.D.

Professor of Immunology
Director, Biomedical Scholars Track Enrichment Program
Academic Office Location:
Immunology
UConn Health
263 Farmington Avenue
Farmington, CT 06030-1319
Phone: 860-679-4118
Fax: 860-679-1868
Website(s):

Immunology Graduate Program

Education
DegreeInstitutionMajor
B.A.Eastern Connecticut State UniversityBiology
Ph.D.Marquette University & Medical College of WisconsinImmunology

Post-Graduate Training
TrainingInstitutionSpecialty
PostdoctoralUniversity of Connecticut Health CenterLung Immunopathology,Dr. Peter Ward – Lab

Awards
Name of Award/HonorAwarding Organization
Research Career Development Award - 1983-1988 NIH
Research Awards - 1981 and 1982 American Lung Association
New Investigator Award - 1981-1984 NIH
Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
NIH Study Section - Lung Cellular, Molecular, and Immunobiology (LCMI) Study SectionCommittee MemberExternalNational20092013
NIH Study Sections - Lung Biology and PathologyStudy SectionCommittee MemberExternalNational19911995
NIH Study Sections - Pathology AStudy SectionCommittee MemberExternalNational19891991
The overall goal of our research is to gain insight into the pathogenic mechanisms involved in asthma and chronic bronchitis. An ovalbumin-induced mouse model of asthma, which closely resembles the development of lung injury in humans is used. Cell-to-cell interactions (cytokines), immune regulation, pulmonary physiology, and collagen metabolism represent areas of concentration. Also, clinical studies in patients involving risk factors associated with asthma as well as new possible therapeutic interventions are currently being investigated.The pathogenic mechanisms involved in the development of asthma are obscure and complex. The pathologic features of the lesion include an allergic inflammatory process and collagen deposition (scar formation). In the healing process there must be an optimal balance between scar formation and regeneration of normal architecture. Unfortunately, in many pulmonary and non-pulmonary disease states this is not the case; abnormal and pathologic amounts of collagen are commonly deposited. The mechanism for this increased collagen synthesis is not understood and may have significant clinical ramifications.
Not accepting Lab Rotation students at this time

Journal Articles

Conference Papers

Other

Reviews