Photo of George Y. Wu, M.D., Ph.D.

George Y. Wu, M.D., Ph.D.

Director, Hepatology Section, Division of Gastroenterology-Hepatology
Herman Lopata Chair in Hepatitis Reseach
Academic Office Location:
Medicine
UConn Health
263 Farmington Avenue
Farmington, CT 06030-1845
Phone: 800-535-6232
860-679-7692
Website(s):

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Education
DegreeInstitutionMajor
B.S.University of RochesterChemistry
M.D., Ph.D.Albert Einstein College of MedicineMedicine/Biochemistry

Post-Graduate Training
TrainingInstitutionSpecialty
InternshipHarlem Hospital CenterMedicine
ResidencyHarlem Hospital Center Medicine
FellowshipAlbert Einstein College of MedicineGastroenterology-Liver Disease

Awards
Name of Award/HonorAwarding Organization
Director, Clinical Research Center (International Division), Southwest Hospital, Chongqing, China
FellowAmerican Association for the Study of Liver Diseases
Top Doctor in the U.S.U.S. News and World Report
Fulbright Scholar
Guest ProfessorshipFaculty of Medicine, University of Osijek, Croatia
Fulbright Specialist Roster Council for International Exchange
Fellow American Gastroenterological Association
CommendationMoroccan American Society for Life Sciences
Consultant ProfessorshipShanghai Second Medical University
Old TurksAssociation of American Physicians
Scientific AwardChinese American Medical Society
Herman Lopata Chair in Hepatitis Research
Gastroenterology Research Group Young Scientist AwardAmerican Gastroenterological Association
Young TurksAmerican Society for Clinical Investigation
Stuart F. Wilson Young Faculty Research Award
Research Career Development AwardNIH
Industry Research Scholar AwardAmerican Gastroenterological Association
Research PrizeAmerican Liver Foundation
Individual National Research Service AwardNIAMDD
Post-Doctoral Fellowship AwardAmerican Liver Foundation
Fellowship AwardGail I. Zuckerman Foundation
NIH Medical Scientist Trainee, M.D.-Ph.D. Fellowship, Albert Einstein College of Medicine
Phi Beta KappaUniversity of Rochester

General gastroenterology including diagnostic and therapeutic upper endoscopy, and colonoscopy, ultrasound-assisted liver biopsy, ultrasound-assisted paracentesis,

Developed liver disease lectures and small group sessions for the 2nd year medical students in Disorders of Metabolism Course: “Complications of Chronic Liver Disease”, and “Serum Liver Tests” and “Fulminant Hepatic Failure”. Have been also involved in the UConn Mini-Medical School program since 2008 in which he annually presents a lecture: “Chronic Viral Hepatitis: What is it and why is it important?”, and was a mentor for shadowing of mini-medical students for cases in GI endoscopy, Careers in Gastroenterology. Served as a Selective advisor for 4th year medical students. Consult Attending, Endoscopy Attending, and medical residents in Continuity Clinic. Local, national and international reputation as a clinical lecturer. Since 2003, have presented 21 invited lectures abroad in China, India, Jordan, Egypt, Morocco, and Croatia.

Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
GI-Hepatology Fellowship ProgramEducation CommitteeMemberUConn HealthUniversity20042008
GI-Hepatology Fellowship ProgramEducation CommitteeDirectorUConn HealthUniversity19892001

Clinical: New antiviral agents for the treatment of hepatitis C, and hepatitis B.Basic Science: Targeted gene delivery, and most recently an immunocompetent animal model for HCV infection.

Accepting Lab Rotation Students: Summer '16, Fall '16, Spring '17

Journal Articles

Books

  • Pocket Handbook of Gastrointestinal Pharmacotherapeutics, 2nd ed.
    George Y. Wu, editor Pocket Handbook of Gastrointestinal Pharmacotherapeutics, 2nd ed. 2016 Aug;
  • Diagnostic and Therapeutic Procedures in Gastroenterology: An Illustrated Guide 2011 Jul;
  • Multiple contributors Molecular Diagnosis and Gene Therapy 1996 Jan;
  • Multiple contributors Liver Diseases: Diagnosis and Therapy Using Specific Receptors and Ligands 1991 Jan;

Book Chapters

  • A Brief Update on the Treatment of Hepatitis C
    Alyssa M. Austria, Vjera Nincevic, and , George Y. Wu Proceedings of the 3rd International Monothematic Conference on Viral Hepatitis C 2017 Jan;
  • The Molecular Basis of Anti-HCV Drug Resistance
    Shaina M.Lynch, and George Y. Wu Proceedings of the 3rd International Monothematic Conference on Viral Hepatitis C 2017 Jan;
  • Hepatitis
    Roopjeet K. Bath and George Y. Wu Pocket Handbook of GI Pharmacotherapeutics 2016 Aug;113-138
  • Pruritus
    Marianna Mavilia, George Y. Wu Pocket Handbook of GI Pharmacotherapeutics 2016 Aug;157-166
  • Polymeric Biomaterials
    Ouyang, E.C., Wu, C.H., and Wu, G.Y. Biocompatible polymers in liver-targeted gene delivery systems 2002 Jan;975-982
  • Meth. Mole. Med. – Nonviral Vectors for Gene Therapy: Methods and Protocols
    Zhong, Bo-Hua, Wu, G.Y., and Wu, C.H. Progress Towards a Synthetic Virus: A Multicomponent System for Liver-Directed DNA Delivery 2001 Jan;
  • Progress in Gene Therapy - Basic and Clinical Frontiers
    Fukuma, T., Wu, G.Y., and Wu, C.H. Liver-selective nucleic acid targeting using the asialoglycoprotein receptor 2000 Jan;
  • Current Concepts of Gene Therapy
    Wu, G.Y. and Wu, C.H. Targeted gene delivery and expression in hepatocytes 1997 Jan;
  • Gene Therapy Protocols
    Findeis, M.A., Wu, C.H., and Wu, G.Y. Methods for Targeted Gene Trans¬fer to Liver Using DNA-Protein Complexes 1997 Jan;
  • Molecular Diagnosis and Gene Therapy
    Wu, G.Y. and Wu, C.H. Gene therapy for hepatic diseases 1997 Jan;
  • Treatments in Hepatology
    Wu, G.Y., and Wu, C.H. Gene therapy and liver diseases 1995 Jan;
  • Methods in Enzymol.
    Findeis, M.A., Wu, C.H. and Wu, G.Y. Ligand-based carrier systems for delivery of DNA to hepatocytes 1994 Jan;
  • Neoglycoconjugates: Preparation and Application
    Lee-Young, A., Wu, C.H., and Wu, G.Y. Delivery of polynucleotides to hepatocytes 1994 Jan;
  • Extrahepatic Manifestations of Liver Diseases
    Wu, G.Y. and Wu, C.H. Advances in gene therapy for liver diseases 1993 Jan;
  • Progress in Liver Diseases
    Makdisi, W.J., Wu, C.H., and Wu, G.Y. Methods of gene transfer into hepatocytes: Progress toward gene therapy 1992 Jan;
  • Seminars in Liver Disease
    Versland, M.R., Wu, C.H., and Wu, G.Y. Strategies for gene therapy in the liver 1992 Jan;
  • Etiology, Pathology, and Treatment of Hepatocellular Carcinoma in North America
    Keegan-Rogers, V., Wu, C.H. and Wu, G.Y. Experimental therapeutic modalities for hepatocellular carcinoma 1991 Jan;
  • Targeted Diagnosis and Therapy of Liver Diseases: Cell Surface Receptors and Liver Directed Agents
    Wu, G.Y. and Wu, C.H. Targeted delivery and expression of foreign genes in hepatocytes 1991 Jan;
  • Therapy of Genetic Diseases
    Wu, G.Y. and Wu, C.H. Delivery and expression of genes in hepatocytes 1991 Jan;

Case Reports

Conference Papers

Editorials

Letters

  • Reply to Testino
    Shifflet A., Wu G.Y. Journal of the Formosan Medical Association 2009 Jan;108(3):264

Monographs

  • Autoimmune Hepatitis
    Bath RK, Wu GY BMJ Best Practice 2015 Jul;

Notes

Reviews

Short Surveys

Title or AbstractTypeSponsor/EventDate/YearLocation
The Molecular and Clinical Bases of Anti-HCV Drug ResistanceThe Molecular and Clinical Bases of Anti-HCV Drug ResistancePlenary LectureEgyptian Society of Updates in Hepatology and Gastroenterology2017Cairo, Egypt
“Eosinophilic Esophagitis”LectureMedical Grand Rounds2016Manchester Memorial Hospital
“Up and Down the GI Tract- A Update”LectureInterstate Physicians Medical Association2016San Antonio, TX
“Wilson’s Disease”LectureMedical Grand Rounds2016Manchester Hospital
"HCV Update"LectureMedical Grand Rounds2016Rockville General Hospital
“Complications of Chronic Liver Disease”LectureUniversity of New England College of Osteopathic Medicine2016Manchester Memorial Hospital
“Acute Hepatitis”LectureResident’s Noon Lecture2016UCONN
“The Molecular Basis of HCV Resistance to Antiviral Agents”LectureInternational Forum on Hepatitis2016Cairo, Egypt
“Clinical Evidence of HCV GT-1 Resistance to Antiviral Agents”Plenary LectureInternational Forum on Hepatitis2016Cairo, Egypt
”Autoimmune Hepatitis”LectureMedical Grand Rounds2016Manchester Memorial Hospital
”Autoimmune Hepatitis”LectureMedical Grand Rounds2016Rockville General Hospital
“Chronic Viral Hepatitis: What is it and why does it matter?”LectureMini-Medical Program2016UCONN
“Serum Liver Tests”LectureUniversity of New England College of Osteopathic Medicine2016Manchester Memorial Hospital
“Iron in Health and Disease”LectureUCONN 1st y Medical Students2016UCONN
“What Makes a Good Research Project: An Editor's Perspective Faculty of Medicine”LectureFaculty of Medicine, University of Osijek2016Osijek, Croatia
“Mentor and Teacher: What’s the Difference?”LectureFaculty of Medicine, University of Osijek2016Osijek, Croatia
“The MD-PHD Program: A Personal Experience”LectureFaculty of Medicine, University of Osijek2016Osijek, Croatia
“Publication of Medical Articles: Strategies for Success”LectureFaculty of Medicine, University of Osijek2016Osijek, Croatia
“Workshop on actual manuscripts”LectureFaculty of Medicine, University of Osijek2016Osijek, Croatia
“C. Difficile Colitis and the Gut Microbiome”LectureMedical Grand Rounds2016Rockville General Hospital
“Hepatitis A, D, and E”LectureUniversity of New England College of Osteopathic Medicine2016Manchester Memorial Hospital
“Introduction of Gastroenterology” “Chronic Viral Hepatitis” “Endoscopy”*LectureUCONN Pre-Med Course2016UCONN
“C. difficile Colitis and the Gut Microbiome”LectureMedical Grand Rounds2016Manchester Memorial Hospital
“Fulminant Hepatic Failure”LectureUniversity of New England College of Osteopathic Medicine2016Manchester Hospital
“Strategies for Publishing Medical Articles in English Journals”LectureJiLin University2016JiLin, China
“Targeted Transplantation of Mitochondria to Hepatocytes”LectureJiLin University2016JiLin, China
“Malabsorption: Clinical Presentation and Diagnostic Tests”LectureNutrition Department, Saint Joseph’s University2016West Hartford, CT
“Celiac Disease”LectureNutrition Department, Saint Joseph’s University2016West Hartford, CT
“Update on HCV Treatment”Plenary LectureThird Annual International Monothematic Conference on Hepatitis C2016Orahovica, Croatia
“Brief Update on HCV Treatment”LectureUCONN HCV Support Group2016UCONN
“Non-Alcoholic Liver Disease”LectureInterstate Physicians Medical Association2016San Antonio, TX
"Meet the Professor"TalkInterstate Physicians Medical Association2016San Antonio, TX
“The Molecular and Clinical Bases for Anti-HCV Drug Resistance “LectureThird Annual International Monothematic Conference on Hepatitis C2016Orahovica, Croatia
“Imaging of Hepatic Lesions”LectureMedical Grand Rounds2016Manchester Memorial Hospital
“Teachers versus Mentors: What’s the Difference”LectureMentorship Course Faculty of Medicine, University of Osijek2016Osijek, Croatia
“Strategies for Publication of Medical Articles”LectureMentorship Course Faculty of Medicine, University of Osijek2016Osijek, Croatia
“Imaging of Hepatic Lesions”LectureMedical Grand Rounds2016Rockville General Hospital
“Pathogenesis and Treatment of Ascites”LectureUniversity of New England College of Osteopathic Medicine2015Manchester Memorial Hospital
“Update on the Pathogenesis and Treat- ment of Hemochromatosis”LectureEndocrine Intercity Grand Rounds/UCONN2015UCONN
“Update on the Pathogenesis and Treatment of HCV”LectureAdvances in Internal Medicine2015UCONN
"Methotrexate Hepatotoxicity"LectureMedical Grand Rounds2015Manchester Memorial Hospital
"Methotrexate Hepatotoxicity"LectureMedical Grand Rounds2015Rockville General Hospital
“A Practical Immunocompetent Animal Model of Hepatitis C Viral Infection”LectureDepartment of Nutritional Sciences2015UCONN Storrs, CT
"Digestive Diseases Mediated by Bacterial Toxins”LectureMedical Microbiology Course2015Misr International University, Cairo, Egypt
"Update on the Pathogenesis and Treatment of HCV"LectureMedical Microbiology Course, School of Pharmacy2015Misr International University, Cairo, Egypt
“Digestive Diseases Caused by Helminths”LectureMedical Microbiology Course, School of Pharmacy2015Misr International University, Cairo, Egypt
“Viral Hepatitis”LectureMedical Microbiology Course, School of Pharmacy2015Misr International University, Cairo, Egypt
“Chronic Viral Hepatitis: What is it and why is it important”LectureMini-Medical Program2015UCONN
“Update on the pathogenesis, and treatment of HCV”LectureThe 22nd Annual GI Symposium Update on the Management of Common GI, Pancrea2015Rutgers, Robert Wood Johnson School of Medicine New Brunswick, NJ
"Wilson’s Disease"LectureMedical Grand Rounds2015Rockville General Hospital
“Viral Hepatitis”LectureAmerican Liver Foundation Clinical Treatment Initiative2015Rushford Treatment Center Middletown, CT
“Iron in Health and Disease”LectureOS3, 2y Medical Students2015UCONN
Targeted Transplantation of Mitochondria to Specific Cell Types”LectureLunch and Learn, Alexion, Corp. Cheshire, CT2015Cheshire, CT
“Update on HBV”LectureGI Fellows Lecture2015UCONN
“PEG-tubes”LectureGI Fellows’ Lecture Series2015UCONN
Foreign Body Ingestion”LectureMedical Grand Rounds2015Manchester Memorial Hospital
”Foreign Body Ingestion”LectureMedical Grand Rounds2015Rockville General Hospital
“Update on HCV Treatment”LectureHCV Support Group2015UCONN
“Hepatitis C Therapy: Current Status and Future Challenges”LectureSecond Annual International Monothematic Conference on Hepatitis C2015Lug, Croatia
“Extrahepatic Manifestations of Hepatitis C”LectureSecond Annual International Monothematic Conference on Hepatitis C2015Lug, Croatia
“Structural Analogs for Inhibition of HCV Replication”LectureSecond Annual International Monothematic Conference on Hepatitis C2015Lug, Croatia
“What Makes a Good Clinical Research Paper?” An Editor's Perspective”LectureFirst International Summit on Medical Research and Publication2015Wuhan, China
“Rescue of Hepatocytes from Lethal Mitochondrial Damage by Targeted Transplantation of Mitochondria”TalkAmerican Association for the Study of Liver Diseases2015San Francisco, CA
“Pathogenesis and Treatment of Ascites”LectureUniversity of New England College of Osteopathic Medicine2015Manchester Memorial Hospital