Faculty Directory > Wu, George
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George Y. Wu, MD, PhDProfessor Emeritus
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- Education & Training
- Clinical Interests
- Teaching
- Committees & Organizations
- Research
- Lab Rotations
- Publications
- Presentations
Education
Post-Graduate Training
Awards
| Degree | Institution | Major |
|---|---|---|
| BS | University of Rochester | Chemistry |
| MD, PhD | Albert Einstein College of Medicine | Medicine/Biochemistry |
Post-Graduate Training
| Training | Institution | Specialty |
|---|---|---|
| Internship | Harlem Hospital Center | Medicine |
| Residency | Harlem Hospital Center | Medicine |
| Fellowship | Albert Einstein College of Medicine | Gastroenterology/Liver Disease |
Awards
| Name of Award/Honor | Awarding Organization |
|---|---|
| Director, Clinical Research Center (International Division), Southwest Hospital, Chongqing, China | |
| Fellow | American Association for the Study of Liver Diseases |
| Top Doctor in the U.S. | U.S. News and World Report |
| Fulbright Scholar | |
| Guest Professorship | Faculty of Medicine, University of Osijek, Croatia |
| Fulbright Specialist Roster | Council for International Exchange |
| Fellow | American Gastroenterological Association |
| Commendation | Moroccan American Society for Life Sciences |
| Consultant Professorship | Shanghai Second Medical University |
| Old Turks | Association of American Physicians |
| Scientific Award | Chinese American Medical Society |
| Herman Lopata Chair in Hepatitis Research | |
| Gastroenterology Research Group Young Scientist Award | American Gastroenterological Association |
| Young Turks | American Society for Clinical Investigation |
| Stuart F. Wilson Young Faculty Research Award | |
| Research Career Development Award | NIH |
| Industry Research Scholar Award | American Gastroenterological Association |
| Research Prize | American Liver Foundation |
| Individual National Research Service Award | NIAMDD |
| Postdoctoral Fellowship Award | American Liver Foundation |
| Fellowship Award | Gail I. Zuckerman Foundation |
| NIH Medical Scientist Trainee, M.D./Ph.D. Fellowship | Albert Einstein College of Medicine |
| Phi Beta Kappa | University of Rochester |
General gastroenterology including diagnostic and therapeutic upper endoscopy and colonoscopy, ultrasound-assisted liver biopsy, and ultrasound-assisted paracentesis
Developed liver disease lectures and small group sessions for the 2nd year medical students in Disorders of Metabolism Course: “Complications of Chronic Liver Disease”, and “Serum Liver Tests” and “Fulminant Hepatic Failure”. Have been also involved in the UConn Mini-Medical School program since 2008 in which he annually presents a lecture: “Chronic Viral Hepatitis: What is it and why is it important?”, and was a mentor for shadowing of mini-medical students for cases in GI endoscopy, Careers in Gastroenterology. Served as a Selective advisor for 4th year medical students. Consult Attending, Endoscopy Attending, and medical residents in Continuity Clinic. Local, national and international reputation as a clinical lecturer. Since 2003, have presented 21 invited lectures abroad in China, India, Jordan, Egypt, Morocco, and Croatia.
| Name & Description | Category | Role | Type | Scope | Start Year | End Year |
|---|---|---|---|---|---|---|
| GI-Hepatology Fellowship Program | Education Committee | Member | UConn Health | University | 2004 | 2008 |
| GI-Hepatology Fellowship Program | Education Committee | Director | UConn Health | University | 1989 | 2001 |
Clinical: New antiviral agents for the treatment of hepatitis C, and hepatitis B.
Basic Science: Targeted gene delivery, and most recently an immunocompetent animal model for HCV infection.
Not accepting students for Lab Rotations at this time
Journal Articles
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Prolonged Direct Hyperbilirubinemia Following Acute Hepatitis: When Not to Worry?
Zhao, Danzhu; Wu, George Y Journal of clinical and translational hepatology 2024 Dec;12(12):985-987
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Changes in Dickkopf-1, but Not Sclerostin, in Gingival Crevicular Fluid Are Associated with Peroral Statin Treatment in Patients with Periodontitis.
Duspara, Kristina; Sikora, Renata; Petrovic, Ana; Kuna Roguljic, Lucija; Matic, Anita; Kralik, Kristina; Roguljic, Hrvoje; Kizivat, Tomislav; Duspara, Mirjana; Igrec, Dunja; Bojanic, Kristina; Smolic, Robert; Vcev, Aleksandar; Wyszynska, Magdalena; Wu, George Y; Smolic, Martina Medicina (Kaunas, Lithuania) 2024 Mar;60(3):
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Laryngopharyngeal Reflux Scoring in a Pediatric Population.
Abicic, Ivan; Covic, Marina; Zjalic, Milorad; Bakula, Marina; Marjanovic, Ksenija; Šestak, Anamarija; Dmitrovic, Branko; Mendeš, Tihana; Smolic, Martina; Wu, George Y; Mihalj, Hrvoje; Zubcic, Željko; Vceva, Andrijana Journal of clinical medicine 2023 Nov;12(23):
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Liraglutide Exerts Protective Effects by Downregulation of PPARγ, ACSL1 and SREBP-1c in Huh7 Cell Culture Models of Non-Alcoholic Steatosis and Drug-Induced Steatosis.
Omanovic Kolaric, Tea; Kizivat, Tomislav; Mihaljevic, Vjera; Zjalic, Milorad; Bilic-Curcic, Ines; Kuna, Lucija; Smolic, Robert; Vcev, Aleksandar; Wu, George Y; Smolic, Martina Current issues in molecular biology 2022 Aug;44(8):3465-3480
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Liver and serum adiponectin levels in non-alcoholic fatty liver disease.
Mavilia, Marianna G; Wu, George Y Journal of digestive diseases 2021 Apr;22(4):214-221
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Celiac Disease and Elevated Liver Enzymes: A Review.
Villavicencio Kim, Jaimy; Wu, George Y Journal of clinical and translational hepatology 2021 Feb;9(1):116-124
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Cytomegalovirus Hepatitis in Immunocompetent and Immunocompromised Hosts.
Da Cunha, Teresa; Wu, George Y Journal of clinical and translational hepatology 2021 Feb;9(1):106-115
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Impact of DAA Treatment on Cardiovascular Disease Risk in Chronic HCV Infection: An Update.
Roguljic, Hrvoje; Nincevic, Vjera; Bojanic, Kristina; Kuna, Lucija; Smolic, Robert; Vcev, Aleksandar; Primorac, Dragan; Vceva, Andrijana; Wu, George Y; Smolic, Martina Frontiers in pharmacology 2021 Jan;12678546
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The accuracy of breast cancer risk self-assessment does not correlate with knowledge about breast cancer and knowledge and attitudes towards primary chemoprevention.
Bojanic, Kristina; Vukadin, Sonja; Grgic, Kaja; Malenica, Luka; Sarcevic, Filip; Smolic, Robert; Kralik, Kristina; Vcev, Aleksandar; Wu, George Y; Smolic, Martina Preventive medicine reports 2020 Dec;20101229
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Impact of Breast Density Awareness on Knowledge about Breast Cancer Risk Factors and the Self-Perceived Risk of Breast Cancer.
Bojanic, Kristina; Vukadin, Sonja; Sarcevic, Filip; Malenica, Luka; Grgic, Kaja; Smolic, Robert; Kralik, Kristina; Bilic Curcic, Ines; Ivanac, Gordana; Wu, George Y; Smolic, Martina Diagnostics (Basel, Switzerland) 2020 Jul;10(7):
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Representation of CYP3A4, CYP3A5 and UGT1A4 Polymorphisms within Croatian Breast Cancer Patients' Population.
Bojanic, Kristina; Kuna, Lucija; Bilic Curcic, Ines; Wagner, Jasenka; Smolic, Robert; Kralik, Kristina; Kizivat, Tomislav; Ivanac, Gordana; Vcev, Aleksandar; Wu, George Y; Smolic, Martina International journal of environmental research and public health 2020 May;17(10):
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Targeted Delivery of Mitochondria to Liver in Rats.
Liu, Xiaocong; Khouri-Farah, Nagham; Wu, Catherine H; Wu, George Y Journal of gastroenterology and hepatology 2020 May;
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Biliary Mucinous Cystadenoma: A Review of the Literature.
Averbukh, Leon D; Wu, David C; Cho, Woo Cheal; Wu, George Y Journal of clinical and translational hepatology 2019 Jun;7(2):149-153
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Diagnostic and Therapeutic Strategies for Peritoneal Tuberculosis: A Review.
Wu, David C; Averbukh, Leon D; Wu, George Y Journal of clinical and translational hepatology 2019 Jun;7(2):140-148
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HCV Extrahepatic Manifestations.
Kuna, Lucija; Jakab, Jelena; Smolic, Robert; Wu, George Y; Smolic, Martina Journal of clinical and translational hepatology 2019 Jun;7(2):172-182
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An Improved Method for Preparation of Uniform and Functional Mitochondria from Fresh Liver.
Farah, Nagham Khouri; Liu, Xiaocong; Wu, Catherine H; Wu, George Y Journal of clinical and translational hepatology 2019 Mar;7(1):46-50
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Mechanisms of Hepatic Cholestatic Drug Injury.
Kolaric, Tea Omanovic; Nincevic, Vjera; Smolic, Robert; Smolic, Martina; Wu, George Y Journal of clinical and translational hepatology 2019 Mar;7(1):86-92
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Aortoenteric Fistula.
Mavilia, Marianna G; Wu, George Y The Journal of the American Osteopathic Association 2019 Feb;119(2):135
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Primary Care Provider Counseling Practices about Adverse Drug Reactions and Interactions in Croatia.
Raguz Lucic, Nikola; Jakab, Jelena; Smolic, Martina; Milas, Ana-Maria; Omanovic Kolaric, Tea; Nincevic, Vjera; Bojanic, Kristina; Kralik, Kristina; Miskulin, Maja; Wu, George Y; Smolic, Robert Journal of clinical medicine 2018 Aug;7(9):
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Dysregulation of fibrosis related genes in HCV induced liver disease.
Dawood, Reham M; El-Meguid, Mai Abd; Ibrahim, Marwa K; Bader El Din, Noha G; Barakat, Ahmed; El-Wakeel, Khaled; Alla, Mohamed Darwish Ahmed Abd; Wu, George Y; El Awady, Mostafa K Gene 2018 Jul;66458-69
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Timing of treatment initiation of direct-acting antivirals for HIV/HCV coinfected and HCV monoinfected patients.
Rice, Donald P; Ordoveza, Michelle A; Palmer, Ann M; Wu, George Y; Chirch, Lisa M AIDS care 2018 Jul;301507-1511
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HCV Therapy Follow-up Fractionation (CTF2) by Intra-PBMC Nested RNA PCR Recognizes Early Virologic Response and Relapse.
Abd Alla, Mohamed Darwish Ahmed; Elibiary, Saleh Ahmed; Elshaboury, Ramy Hassan; Wu, George Y; Dawood, Reham M; El Awady, Mostafa Kamel Journal of clinical and translational hepatology 2018 Jun;6(2):147-154
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Models of Drug Induced Liver Injury (DILI) - Current Issues and Future Perspectives.
Kuna, Lucija; Bozic, Ivana; Kizivat, Tomislav; Bojanic, Kristina; Mrso, Margareta; Kralj, Edgar; Smolic, Robert; Wu, George Y; Smolic, Martina Current drug metabolism 2018 May;19830-838
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Occult HCV Infection (OCI) Diagnosis in Cirrhotic and Non-cirrhotic Naïve Patients by Intra-PBMC Nested Viral RNA PCR.
Abd Alla, Mohamed Darwish Ahmed; Elibiary, Saleh Ahmed; Wu, George Y; El-Awady, Mostafa Kamel Journal of clinical and translational hepatology 2017 Dec;5(4):319-326
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Targeted Transplantation of Mitochondria to Hepatocytes
Nidhi Gupta, Catherine H. Wu, and George Y. Wu Hepatic Medicine: Evidence and Research 2016 Dec;8115-134
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A Novel Dual Snare Technique for Removal of Long Sharp Foreign Bodies.
Lynch, Shaina M; Wu, George Y Journal of digestive diseases 2016 Jan;17274-276
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Secondary Structural Elements of the HCV X-region Involved in Viral Replication.
Gupta, Nidhi; Wu, Catherine H; Wu, George Y Journal of clinical and translational hepatology 2015 Jul;3(1):1-8
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Effects of short RNA structural analogues against hepatitis C virus genotypes 2, 3 and 4 in replicon cells.
Elshaffei, Ismail M; Gupta, Nidhi; Wu, Catherine H; Wu, David C; Hammad, Lamiaa N; Abo-Elmatty, Dina M; Mesbah, Noha M; Wu, George Y Journal of digestive diseases 2015 Apr;16(8):449-55
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The Molecular and Structural Basis of HBV-Resistance to Nucleos(t)ide Analogs.
N. Gupta, M. Goyal, C.H. Wu, G.Y. Wu J Clin Trans Hepatol 2014 Dec;
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An ironic case of liver infections: Yersinia enterocolitis in the setting of thalassemia.
Selsky, Nathan; Forouhar, Faripour; Wu, George Y World journal of gastroenterology 2013 Oct;19(37):6296-8
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Sessile serrated adenomas in the proximal colon are likely to be flat, large and occur in smokers.
Rustagi, Tarun; Rangasamy, Priya; Myers, Matthew; Sanders, Melinda; Vaziri, Haleh; Wu, George Y; Birk, John W; Protiva, Petr; Anderson, Joseph C World journal of gastroenterology 2013 Aug;19(32):5271-7
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An engineered multidomain fungicidal peptide against plant fungal pathogens.
Qiu, Xiao-Qing; Tong, Chong-Yi; Zhong, Zhen-Qi; Wang, Wan-Qi; Zuo, Yue-Wen; Huang, Yun; Zhang, Lu; Zhang, Xiang-Li; Zhang, Hong-Xia; Li, Rong-Qi; Wang, Jing; Chen, Hao; Li, Yun-Yun; Wu, George; Wang, He Sheng li xue bao : [Acta physiologica Sinica] 2013 Aug;65(4):417-32
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Pharmacogenetic selection of transplanted human hepatocytes in immunocompetent rats.
Smolic, Martina; Wu, Catherine H; Madadi, Shilpa; Gupta, Nidhi; Smolic, Robert; Coash, Marcy; Smith, Jeanette; Wu, George Y Journal of digestive diseases 2012 Nov;13(11):579-87
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Animal models for the study of hepatitis C virus infection and replication.
MacArthur, Kristin L; Wu, Catherine H; Wu, George Y World journal of gastroenterology 2012 Jun;18(23):2909-13
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Endoscopic removal of a long sharp metallic foreign body by a snared magnet: an attractive solution.
Coash, Marcy; Wu, George Y Journal of digestive diseases 2012 Apr;13(4):239-41
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Granulomatous liver diseases: a review.
Coash, Marcy; Forouhar, Faripour; Wu, Catherine H; Wu, George Y Journal of the Formosan Medical Association = Taiwan yi zhi 2012 Jan;111(1):3-13
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Effects of PEG-interferon-alpha-2A on Schistosoma mansoni infection in mice.
Draz, Hossam M; Mahmoud, Sohair S; Ashour, Esmat; Shaker, Yehia M; Wu, Catherine H; Wu, George Y The Journal of parasitology 2010 Aug;96(4):703-8
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Inhibition of hepatitis C virus replication by single-stranded RNA structural mimics.
Smolic, Robert; Smolic, Martina; Andorfer, John H; Wu, Catherine H; Smith, Robert M; Wu, George Y World journal of gastroenterology 2010 May;16(17):2100-8
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Host susceptibility to schistosomes: effect of host sera on cell proliferation of Schistosoma mansoni schistosomula.
Draz, Hossam M; Ashour, Esmat; Shaker, Yehia M; Khattab, Hany M; Wu, Catherine H; Wu, George Y The Journal of parasitology 2008 Dec;94(6):1249-52
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Human uridine-cytidine kinase phosphorylation of ribavirin: a convenient method for activation of ribavirin for conjugation to proteins.
Virovic Jukic, Lucija; Duvnjak, Marko; Wu, Catherine H; Wu, George Y Journal of biomedical science 2008 Mar;15(2):205-13
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'Where the money is': a case report of the successful removal of a large number of coins by esophagogastroduodenoscopy utilizing a Roth net.
Raynor, Kathleen M; Wu, George Y Journal of digestive diseases 2007 Aug;8(3):160-1
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The contribution of methotrexate exposure and host factors on transcriptional variance in human liver.
Belinsky, Glenn S; Parke, Ann L; Huang, Qihong; Blanchard, Kerry; Jayadev, Supriya; Stoll, Raymond; Rothe, Marti; Achenie, Luke E K; Gupta, Rishi R; Wu, George Y; Rosenberg, Daniel W Toxicological sciences : an official journal of the Society of Toxicology 2007 Jun;97(2):582-94
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Positional effects and strand preference of RNA interference against hepatitis C virus target sequences.
Smith, R M; Smolic, R; Volarevic, M; Wu, G Y Journal of viral hepatitis 2007 Mar;14(3):194-212
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A novel G418 conjugate results in targeted selection of genetically protected hepatocytes without bystander toxicity.
Volarevic, Martina; Wu, Catherine H; Smolic, Robert; Andorfer, John H; Wu, George Y Bioconjugate chemistry 2007 Jan;18(6):1965-71
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siRNA-resistance in treated HCV replicon cells is correlated with the development of specific HCV mutations.
Konishi, Masayoshi; Wu, Catherine H; Kaito, Masahiko; Hayashi, Kazuhiko; Watanabe, Shozo; Adachi, Yukihiko; Wu, George Y Journal of viral hepatitis 2006 Nov;13(11):756-61
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Inhibition of Pkhd1 impairs tubulomorphogenesis of cultured IMCD cells.
Mai, Weiyi; Chen, Dong; Ding, Tianbing; Kim, Ingyu; Park, Sujun; Cho, Sae-youll; Chu, Julia S F; Liang, Dan; Wang, Ning; Wu, Dianqing; Li, Song; Zhao, Ping; Zent, Roy; Wu, Guanqing Molecular biology of the cell 2005 Sep;16(9):4398-409
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Endogenously expressed multimeric self-cleaving hammerhead ribozymes ablate mutant collagen in cellulo.
Peace, Belinda E; Florer, Jane B; Witte, David; Smicun, Yoel; Toudjarska, Iva; Wu, George; Kilpatrick, Michael W; Tsipouras, Petros; Wenstrup, Richard J Molecular therapy : the journal of the American Society of Gene Therapy 2005 Jul;12(1):128-36
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A novel immunocompetent rat model of HCV infection and hepatitis.
Wu, George Y; Konishi, Masayoshi; Walton, Cherie M; Olive, Denise; Hayashi, Kazuhiko; Wu, Catherine H Gastroenterology 2005 May;128(5):1416-23
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A novel engineered peptide, a narrow-spectrum antibiotic, is effective against vancomycin-resistant Enterococcus faecalis.
Qiu, Xiao-Qing; Zhang, Jie; Wang, He; Wu, George Y Antimicrobial agents and chemotherapy 2005 Mar;49(3):1184-9
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Secondary structure and hybridization accessibility of the hepatitis C virus negative strand RNA 5'-terminus.
Smith, R M; Wu, G Y Journal of viral hepatitis 2004 Mar;11(2):115-23
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PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells.
Zhang, Ming-Zhi; Mai, Weiyi; Li, Cunxi; Cho, Sae-youll; Hao, Chuanming; Moeckel, Gilbert; Zhao, Runxiang; Kim, Ingyu; Wang, Jikui; Xiong, Huaqi; Wang, Hong; Sato, Yasunori; Wu, Yizhong; Nakanuma, Yasuni; Lilova, Marusia; Pei, York; Harris, Raymond C; Li, Song; Coffey, Robert J; Sun, Le; Wu, Dianqing; Chen, Xing-Zhen; Breyer, Matthew D; Zhao, Zhizhuang Joe; McKanna, James A; Wu, Guanqing Proceedings of the National Academy of Sciences of the United States of America 2004 Feb;101(8):2311-6
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Delivery of hepatitis B virus therapeutic agents using asialoglycoprotein receptor-based liver-specific targeting.
Konishi, Masayoshi; Wu, Catherine H; Wu, George Y Methods in molecular medicine 2004 Jan;96163-73
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An engineered multidomain bactericidal peptide as a model for targeted antibiotics against specific bacteria.
Qiu, Xiao-Qing; Wang, He; Lu, Xiao-Fong; Zhang, Jie; Li, Sheng-Fu; Cheng, Gang; Wan, Lin; Yang, Li; Zuo, Jun-Yong; Zhou, Yu-Qi; Wang, Hai-Yun; Cheng, Xin; Zhang, Su-Hua; Ou, Zheng-Rong; Zhong, Zi-Cheng; Cheng, Jing-Qiu; Li, You-Ping; Wu, George Y Nature biotechnology 2003 Dec;21(12):1480-5
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Enhanced intracellular availability and survival of hammerhead ribozymes increases target ablation in a cellular model of osteogenesis imperfecta.
Smicun, Y; Kilpatrick, M W; Florer, J; Toudjarska, I; Wu, G; Wenstrup, R J; Tsipouras, P Gene therapy 2003 Nov;10(24):2005-12
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Inhibition of HBV replication by siRNA in a stable HBV-producing cell line.
Konishi, Masayoshi; Wu, Catherine H; Wu, George Y Hepatology (Baltimore, Md.) 2003 Oct;38(4):842-50
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Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42.
Li, Zhong; Hannigan, Michael; Mo, Zhicheng; Liu, Bo; Lu, Wei; Wu, Yue; Smrcka, Alan V; Wu, Guanqing; Li, Lin; Liu, Mingyao; Huang, Chi-Kuang; Wu, Dianqing Cell 2003 Jul;114(2):215-27
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Hepatitis B virus infection of transplanted human hepatocytes causes a biochemical and histological hepatitis in immunocopetentent rats.
Wu, Catherine H; Ouyang, Edwin C; Walton, Cherie; Promrat, Kittichai; Forouhar, Faripour; Wu, George Y World journal of gastroenterology 2003 May;9(5):978-83
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Conjugation of an antisense oligodeoxynucleotide to ribonuclease h results in sequence-specific cleavage and intracellular inhibition of HCV gene expression.
Fukuma, Toshiko; Walton, Cherie M; Wu, Catherine H; Wu, George Y Bioconjugate chemistry 2003 Jan;14(2):295-301
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Secondary structure and hybridization accessibility of hepatitis C virus 3'-terminal sequences.
Smith, Robert M; Walton, Cherie M; Wu, Catherine H; Wu, George Y Journal of virology 2002 Oct;76(19):9563-74
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Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1.
Mao, Junhao; Maye, Peter; Kogerman, Priit; Tejedor, Francisco J; Toftgard, Rune; Xie, Wei; Wu, Guanqing; Wu, Dianqing The Journal of biological chemistry 2002 Sep;277(38):35156-61
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Evaluation of multicomponent non-viral vectors for liver directed gene delivery.
Wu, Catherine H; Sapozhnikov, Eugene; Wu, George Y Journal of drug targeting 2002 Mar;10(2):105-11
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Targeted gene transfer to liver using protein-DNA complexes.
Wu, Catherine H; Walton, Cherie M; Wu, George Y Methods in molecular medicine 2002 Jan;6915-23
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Liver cell transplantation -- novel animal model for human hepatic viral infections.
Wu, C H; Ouyang, E C; Walton, C; Wu, G Y Croatian medical journal 2001 Aug;42(4):446-50
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Targeted polynucleotides for inhibition of hepatitis B and C viruses.
Wu, G Y; Walton, C M; Wu, C H Croatian medical journal 2001 Aug;42(4):463-6
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Transplantation of human hepatocytes into tolerized genetically immunocompetent rats.
Ouyang, E C; Wu, C H; Walton, C; Promrat, K; Wu, G Y World journal of gastroenterology 2001 Jun;7(3):324-30
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Human hepatocytes transplanted into genetically immunocompetent rats are susceptible to infection by hepatitis B virus in situ.
Wu, C H; Ouyang, E C; Walton, C M; Wu, G Y Journal of viral hepatitis 2001 Mar;8(2):111-9
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A ribonuclease H-oligo DNA conjugate that specifically cleaves hepatitis B viral messenger RNA.
Walton, C M; Wu, C H; Wu, G Y Bioconjugate chemistry 2001 Jan;12(5):770-5
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Transplantation of human hepatocytes into tolerized genetically immunocompetent rats.
Ouyang EC, Wu CH, Walton CM, Promrat K and Wu GY. World Journal of Gastroenterology 2001 Jan;7324-330
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Transfection and expression of HCV-NS5B gene in Huh-7 cells.
Fang, J; Ouyang, E; Wu, C H; Wu, G Y; Qiu, D; Xiao, S Chinese medical journal 2000 Jul;113(7):602-5
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Gene therapy for metabolic diseases of the liver.
Promrat, K., Wu, GY. and Wu, CH. BioDrugs 2000 Jan;13177-188
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Genetic therapy of hepatic diseases.
Shetty, K., Wu, GY. and Wu, CH. Gut 2000 Jan;46136-139
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Hydrodynamic delivery.
Suda, Takeshi; Liu, Dexi Advances in genetics 2000 Jan;8989-111
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Liver-selective nucleic acid targeting using the asialoglycoprotein receptor.
Fukuma, T., Wu, GY. and Wu, CH. Gene Ther Reg 2000 Jan;179-94
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Targeted inhibition of type I procollagen synthesis by antisense DNA oligonucleotides.
Wu, CH., Walton, CM. and Wu, GY. Gene Ther Reg 2000 Jan;11-13
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A DNA delivery system containing listeriolysin O results in enhanced hepatocyte-directed gene expression.
Walton, Cherie M; Wu, Catherine H; Wu, George Y World journal of gastroenterology : WJG 1999 Dec;5(6):465-469
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Inhibition of hepatitis C virus-directed gene expression by a DNA ribonuclease.
Oketani, M; Asahina, Y; Wu, C H; Wu, G Y Journal of hepatology 1999 Oct;31(4):628-34
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A method for purification of listeriolysin O from a hypersecretor strain of Listeria monocytogenes.
Walton, C M; Wu, C H; Wu, G Y Protein expression and purification 1999 Mar;15(2):243-5
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Multicomponent DNA carrier with a vesicular stomatitis virus G-peptide greatly enhances liver-targeted gene expression in mice.
Schuster, M J; Wu, G Y; Walton, C M; Wu, C H Bioconjugate chemistry 1999 Jan;10(6):1075-83
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Human portal serum stimulates cell proliferation in immature Schistosoma mansoni.
Shaker, Y M; Wu, C H; el-Shobaki, F A; Ashour, E; Khattab, H M; Draz, H M; Kamel, R; Wu, G Y Parasitology 1998 Oct;117 ( Pt 4)(4):293-9
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Chimeric oligonucleotides: an exciting answer that raises more questions.
Schuster, M J; Wu, G Y Hepatology (Baltimore, Md.) 1998 Aug;28(2):594-6
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DNA ribonucleases that are active against intracellular hepatitis B viral RNA targets.
Asahina, Y; Ito, Y; Wu, C H; Wu, G Y Hepatology (Baltimore, Md.) 1998 Aug;28(2):547-54
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Targeted inhibition of hepatitis C virus-directed gene expression in human hepatoma cell lines.
Wu, C H; Wu, G Y Gastroenterology 1998 Jun;114(6):1304-12
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Recent advances in gene therapy of GI and liver diseases.
Wu, G Y Zhonghua Minguo xiao er ke yi xue hui za zhi [Journal]. Zhonghua Minguo xiao er ke yi xue hui 1998 Jan;39(5):297-300
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Receptor-mediated delivery of foreign genes to hepatocytes.
Wu, GY. and Wu, CH. Adv. Drug Del. Revs. 1998 Jan;29243-248
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Design and preparation of a multimeric self-cleaving hammerhead ribozyme.
Ruiz, J; Wu, C H; Ito, Y; Wu, G Y BioTechniques 1997 Feb;22(2):338-45
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Listeriolysin O potentiates immunotoxin and bleomycin cytotoxicity.
Kerr, D E; Wu, G Y; Wu, C H; Senter, P D Bioconjugate chemistry 1997 Jan;8(6):781-4
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Intracellular cleavage of hepatitis C virus RNA and inhibition of viral protein translation by hammerhead ribozymes.
Sakamoto, N; Wu, C H; Wu, G Y The Journal of clinical investigation 1996 Dec;98(12):2720-8
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Delivery of a hammerhead ribozyme specifically down-regulates the production of fibrillin-1 by cultured dermal fibroblasts.
Kilpatrick, M W; Phylactou, L A; Godfrey, M; Wu, C H; Wu, G Y; Tsipouras, P Human molecular genetics 1996 Dec;5(12):1939-44
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Inhibition of hepatitis B virus replication by targeted pretreatment of complexed antisense DNA in vitro.
Nakazono, K; Ito, Y; Wu, C H; Wu, G Y Hepatology (Baltimore, Md.) 1996 Jun;23(6):1297-303
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A collagen enhancer-promoter construct in transgenic mice is markedly stimulated by ethanol administration.
Walton, C M; Wu, G Y; Petruff, C A; Clark, S H; Lichtler, A C; Wu, C H Hepatology (Baltimore, Md.) 1996 Feb;23(2):310-5
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Microtubular disruption prolongs the expression of human bilirubin-uridinediphosphoglucuronate-glucuronosyltransferase-1 gene transferred into Gunn rat livers.
Chowdhury, N R; Hays, R M; Bommineni, V R; Franki, N; Chowdhury, J R; Wu, C H; Wu, G Y The Journal of biological chemistry 1996 Jan;271(4):2341-6
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A hepatocyte-targeted conjugate capable of delivering biologically active colchicine in vitro.
Plourde, R; Phillips, A T; Wu, C H; Hays, R M; Chowdhury, J; Chowdhury, N; Wu, G Y Bioconjugate chemistry 1996 Jan;7(1):131-7
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Fate of DNA targeted to hepatocytes by asialoglycoprotein polylysine conjugates.
Wu, G W; Chowdhury, J R; Bommineni, V R; Basu, S K; Wu, C H; Chowdhury, N R Proceedings of the Association of American Physicians 1995 Jul;107(2):211-7
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Depolymerization of hepatocellular microtubules after partial hepatectomy.
Bommineni, V R; Chowdhury, N R; Wu, G Y; Wu, C H; Franki, N; Hays, R M; Chowdhury, J R The Journal of biological chemistry 1994 Oct;269(40):25200-5
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Incorporation of adenovirus into a ligand-based DNA carrier system results in retention of original receptor specificity and enhances targeted gene expression.
Wu, G Y; Zhan, P; Sze, L L; Rosenberg, A R; Wu, C H The Journal of biological chemistry 1994 Apr;269(15):11542-6
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Preparation of asialoorosomucoid-polylysine conjugates.
McKee, T D; DeRome, M E; Wu, G Y; Findeis, M A Bioconjugate chemistry 1994 Jan;5(4):306-11
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Lipocytes from fibrotic rat liver have an impaired feedback response to procollagen propeptides.
Ikeda, H; Wu, G Y; Wu, C H The American journal of physiology 1993 Jan;264(1 Pt 1):G157-62
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Specific inhibition of hepatitis B viral gene expression in vitro by targeted antisense oligonucleotides.
Wu, G Y; Wu, C H The Journal of biological chemistry 1992 Jun;267(18):12436-9
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Evidence that an iron chelator regulates collagen synthesis by decreasing the stability of procollagen mRNA.
Ikeda, H; Wu, G Y; Wu, C H Hepatology (Baltimore, Md.) 1992 Feb;15(2):282-7
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Chemical modification of an ecotropic murine leukemia virus results in redirection of its target cell specificity.
Neda, H; Wu, C H; Wu, G Y The Journal of biological chemistry 1991 Aug;266(22):14143-6
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Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats.
Wu, G Y; Wilson, J M; Shalaby, F; Grossman, M; Shafritz, D A; Wu, C H The Journal of biological chemistry 1991 Aug;266(22):14338-42
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Propeptide-mediated regulation of procollagen synthesis in IMR-90 human lung fibroblast cell cultures. Evidence for transcriptional control.
Wu, C H; Walton, C M; Wu, G Y The Journal of biological chemistry 1991 Feb;266(5):2983-7
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Targeted protection of hepatocytes from galactosamine toxicity in vivo.
Keegan-Rogers, V; Wu, G Y Cancer chemotherapy and pharmacology 1990 Jan;26(2):93-6
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Targeting genes: delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo.
Wu, C H; Wilson, J M; Wu, G Y The Journal of biological chemistry 1989 Oct;264(29):16985-7
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Immunotargeting in the diagnosis and treatment of liver cancer.
Keegan-Rogers, V; Wu, G Y Hepatology (Baltimore, Md.) 1989 Apr;9(4):646-8
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Receptor-mediated gene delivery and expression in vivo.
Wu, G Y; Wu, C H The Journal of biological chemistry 1988 Oct;263(29):14621-4
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Targeted antagonism of galactosamine toxicity in normal rat hepatocytes in vitro.
Wu, G Y; Keegan-Rogers, V; Franklin, S; Midford, S; Wu, C H The Journal of biological chemistry 1988 Apr;263(10):4719-23
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Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro.
Wu, G Y; Wu, C H Biochemistry 1988 Feb;27(3):887-92
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Receptor-mediated in vitro gene transformation by a soluble DNA carrier system.
Wu, G Y; Wu, C H The Journal of biological chemistry 1987 Apr;262(10):4429-32
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Targeted inhibition of transferrin-mediated iron uptake in Hep G2 hepatoma cells.
Wu, G Y; Wu, C H The Journal of biological chemistry 1986 Dec;261(36):16834-7
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Evidence for pretranslational regulation of collagen synthesis by procollagen propeptides.
Wu, C H; Donovan, C B; Wu, G Y The Journal of biological chemistry 1986 Aug;261(23):10482-4
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Portal serum constituents possible determinants for anatomical localization ofSchistosoma mansoni during maturation and reproduction.
Wu, G Y; Wu, C H Journal of chemical ecology 1986 Aug;12(8):1797-803
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Limitation on sensitivity of measuring collagen degradation: studies with cultured liver cells.
Bienkowski, R S; Wu, C H; Wu, G Y Connective tissue research 1986 Jan;14(3):213-9
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Portal serum constituents possible determinants for anatomical localization of Schistosoma mansoni during maturation and reproduction
Wu G.Y., Wu C.H. Journal of Chemical Ecology 1986 Jan;12(8):1797-1803
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Stimulation of Schistosoma mansoni oviposition in vitro by animal and human portal serum.
Wu, G Y; Wu, C H; Dunn, M A; Kamel, R The American journal of tropical medicine and hygiene 1985 Jul;34(4):750-3
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In-vitro catabolism of L-histidine by adult Schistosoma mansoni.
Saber, M A; Wu, G Journal of the Egyptian Society of Parasitology 1985 Jun;15(1):29-39
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Periodate oxidation products of hydroxylysine in the synthesis of 5-substituted prolines.
Wu, G Y; Seifter, S Analytical biochemistry 1985 May;147(1):103-7
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Acetaminophen hepatotoxicity and targeted rescue: a model for specific chemotherapy of hepatocellular carcinoma.
Wu, G Y; Wu, C H; Rubin, M I Hepatology (Baltimore, Md.) 1985 Jan;5(5):709-13
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Activity and regulation of low density lipoprotein receptors in a human hepatoblastoma cell line.
Wu, G Y; Wu, C H; Rifici, V A; Stockert, R J Hepatology (Baltimore, Md.) 1984 Jan;4(6):1190-4
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Model for specific rescue of normal hepatocytes during methotrexate treatment of hepatic malignancy.
Wu, G Y; Wu, C H; Stockert, R J Proceedings of the National Academy of Sciences of the United States of America 1983 May;80(10):3078-80
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Specificity of trypsin and carboxypeptidase B for hydroxylysine residues in denatured collagens.
Wu, G Y; Pereyra, B; Seifter, S Biochemistry 1981 Jul;20(15):4321-4
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A new method for the preparation of delta 1-pyrroline 5-carboxylic acid and proline.
Wu, G Y; Seifter, S Analytical biochemistry 1975 Aug;67(2):413-21
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The 24-hour plasma thyroxin profile in normal man.
O'Connor, J F; Wu, G Y; Gallagher, T F; Hellman, L The Journal of clinical endocrinology and metabolism 1974 Oct;39(4):765-71
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Bilirubin mono- and diglucuronide formation by human liver in vitro: assay by high-pressure liquid chromatography.
Chowdhury, J R; Chowdhury, N R; Wu, G; Shouval, R; Arias, I M Hepatology (Baltimore, Md.) 1(6):622-7
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Development of molecular hybridization technology to evaluate albumin and procollagen mRNA content in baboons and man.
Weiner, F R; Czaja, M J; Giambrone, M A; Wu, C H; Wu, G Y; Zern, M A Hepatology (Baltimore, Md.) 7(1 Suppl):19S-25S
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The nature of the collagen in hepatic fibrosis in advanced murine schistosomiasis.
Wu, C H; Giambrone, M A; Howard, D J; Rojkind, M; Wu, G Y Hepatology (Baltimore, Md.) 2(3):366-71
Books
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Diagnostic and Therapeutic Procedures in Gastroenterology, An Illustrated Guide
Clinical Gastroenterology 2018 Jan;
-
Pocket Handbook of Gastrointestinal Pharmacotherapeutics, 2nd ed.
George Y. Wu, editor Pocket Handbook of Gastrointestinal Pharmacotherapeutics, 2nd ed. 2016 Aug;
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Diagnostic and Therapeutic Procedures in Gastroenterology: An Illustrated Guide 2011 Jul;
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Multiple contributors Molecular Diagnosis and Gene Therapy 1996 Jan;
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Multiple contributors Liver Diseases: Diagnosis and Therapy Using Specific Receptors and Ligands 1991 Jan;
Book Chapters
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Ultrasound-Guided/Ultrasound-Assisted Percutaneous Liver Biopsy
Roopjeet K. Bath, George Y. Wu Diagnostic and Therapeutic Procedures in Gastroenterology 2018 Feb;339-347
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A Brief Update on the Treatment of Hepatitis C
Alyssa M. Austria, Vjera Nincevic, and , George Y. Wu Proceedings of the 3rd International Monothematic Conference on Viral Hepatitis C 2017 Jan;
-
The Molecular Basis of Anti-HCV Drug Resistance
Shaina M.Lynch, and George Y. Wu Proceedings of the 3rd International Monothematic Conference on Viral Hepatitis C 2017 Jan;
-
Hepatitis
Roopjeet K. Bath and George Y. Wu Pocket Handbook of GI Pharmacotherapeutics 2016 Aug;113-138
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Pruritus
Marianna Mavilia, George Y. Wu Pocket Handbook of GI Pharmacotherapeutics 2016 Aug;157-166
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Polymeric Biomaterials
Ouyang, E.C., Wu, C.H., and Wu, G.Y. Biocompatible polymers in liver-targeted gene delivery systems 2002 Jan;975-982
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Meth. Mole. Med. – Nonviral Vectors for Gene Therapy: Methods and Protocols
Zhong, Bo-Hua, Wu, G.Y., and Wu, C.H. Progress Towards a Synthetic Virus: A Multicomponent System for Liver-Directed DNA Delivery 2001 Jan;
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Progress in Gene Therapy - Basic and Clinical Frontiers
Fukuma, T., Wu, G.Y., and Wu, C.H. Liver-selective nucleic acid targeting using the asialoglycoprotein receptor 2000 Jan;
-
Current Concepts of Gene Therapy
Wu, G.Y. and Wu, C.H. Targeted gene delivery and expression in hepatocytes 1997 Jan;
-
Gene Therapy Protocols
Findeis, M.A., Wu, C.H., and Wu, G.Y. Methods for Targeted Gene Trans¬fer to Liver Using DNA-Protein Complexes 1997 Jan;
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Molecular Diagnosis and Gene Therapy
Wu, G.Y. and Wu, C.H. Gene therapy for hepatic diseases 1997 Jan;
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Treatments in Hepatology
Wu, G.Y., and Wu, C.H. Gene therapy and liver diseases 1995 Jan;
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Methods in Enzymol.
Findeis, M.A., Wu, C.H. and Wu, G.Y. Ligand-based carrier systems for delivery of DNA to hepatocytes 1994 Jan;
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Neoglycoconjugates: Preparation and Application
Lee-Young, A., Wu, C.H., and Wu, G.Y. Delivery of polynucleotides to hepatocytes 1994 Jan;
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Extrahepatic Manifestations of Liver Diseases
Wu, G.Y. and Wu, C.H. Advances in gene therapy for liver diseases 1993 Jan;
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Progress in Liver Diseases
Makdisi, W.J., Wu, C.H., and Wu, G.Y. Methods of gene transfer into hepatocytes: Progress toward gene therapy 1992 Jan;
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Seminars in Liver Disease
Versland, M.R., Wu, C.H., and Wu, G.Y. Strategies for gene therapy in the liver 1992 Jan;
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Etiology, Pathology, and Treatment of Hepatocellular Carcinoma in North America
Keegan-Rogers, V., Wu, C.H. and Wu, G.Y. Experimental therapeutic modalities for hepatocellular carcinoma 1991 Jan;
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Targeted Diagnosis and Therapy of Liver Diseases: Cell Surface Receptors and Liver Directed Agents
Wu, G.Y. and Wu, C.H. Targeted delivery and expression of foreign genes in hepatocytes 1991 Jan;
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Therapy of Genetic Diseases
Wu, G.Y. and Wu, C.H. Delivery and expression of genes in hepatocytes 1991 Jan;
Case Reports
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Esophageal Squamous Papilloma: A Case Series and Literature Review.
Mavilia, Marianna G; Wu, George Y Journal of digestive diseases 2017 Aug;19254-256
Conference Papers
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Gene therapy for viral hepatitis: Prospects for the design and delivery of nucleic acid pharmaceuticals
Smith R.M., Wu G.Y. Viral Hepatitis Reviews 2000 Jan;6(4-Jan):129-141
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Gene therapy: Recent advances and applications in gastroenterology and hepatology
Ouyang E.C., Wu G.Y. Journal of Gastroenterology and Hepatology 1998 Jan;13(SUPPL. NOV.):
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Targeted therapy for viral hepatitis
Plourde R., Wu G.Y. Advanced Drug Delivery Reviews 1995 Jan;17(3):311-315
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Receptor-mediated gene delivery and expression in hepatocytes
Wu G.Y., Wilson J.M., Wu C.H. European Journal of Pharmacology 1990 Jan;183(1):147
Editorials
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Non-alcoholic fatty liver disease and the metabolic syndrome: effects of weight loss and a review of popular diets. Are low carbohydrate diets the answer?
Gill, Harjot K; Wu, George Y World journal of gastroenterology 2006 Jan;12(3):345-53
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Gene therapy for hepatocellular carcinoma: progress but many stones yet unturned!
Schuster, M J; Wu, G Y Gastroenterology 1997 Feb;112(2):656-9
Letters
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Reply to Testino
Shifflet A., Wu G.Y. Journal of the Formosan Medical Association 2009 Jan;108(3):264
Monographs
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Autoimmune Hepatitis
Bath RK, Wu GY BMJ Best Practice 2019 Apr;
Notes
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Getting to the core of the matter.
Hassan, N; Wu, G Y Nature medicine 1995 Mar;1(3):210-1
Reviews
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Effects of Transjugular Intrahepatic Portosystemic Shunt on Renal and Pulmonary Function in Hepatic Decompensation with and without Hepatorenal and Hepatopulmonary Syndromes: A Review.
Abdelwahed, Ahmed H; Aboeldahb, Moataz; Wu, George Y Journal of clinical and translational hepatology 2024 Sep;12(9):780-791
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Heritable Chronic Cholestatic Liver Diseases: A Review.
Tidwell, Jasmine; Wu, George Y Journal of clinical and translational hepatology 2024 Aug;12(8):726-738
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Subnormal Serum Liver Enzyme Levels: A Review of Pathophysiology and Clinical Significance.
Youssef, Elham M; Wu, George Y Journal of clinical and translational hepatology 2024 Apr;12(4):428-435
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Genetics of Gallstone Disease and Their Clinical Significance: A Narrative Review.
Costa, Christopher J; Nguyen, Minh Thu T; Vaziri, Haleh; Wu, George Y Journal of clinical and translational hepatology 2024 Mar;12(3):316-326
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Focal Nodular Hyperplasia: A Comprehensive Review with a Particular Focus on Pathogenesis and Complications.
Villavicencio Kim, Jaimy; Wu, George Y Journal of clinical and translational hepatology 2024 Feb;12(2):182-190
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Unique Genetic Features of Lean NAFLD: A Review of Mechanisms and Clinical Implications.
Tidwell, Jasmine; Wu, George Y Journal of clinical and translational hepatology 2024 Jan;12(1):70-78
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Novel Approaches to Inhibition of HBsAg Expression from cccDNA and Chromosomal Integrants: A Review.
Abdelwahed, Ahmed H; Heineman, Brent D; Wu, George Y Journal of clinical and translational hepatology 2023 Dec;11(7):1485-1497
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Noninvasive Fibrosis Assessment in Chronic Hepatitis C Infection: An Update.
Bojanic, Kristina; Bogojevic, Mirta Sudaric; Vukadin, Sonja; Sikora, Renata; Ivanac, Gordana; Lucic, Nikola Raguz; Smolic, Martina; Tabll, Ashraf A; Wu, George Y; Smolic, Robert Journal of clinical and translational hepatology 2023 Oct;11(5):1228-1238
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Biomarkers for Assessing Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus on Sodium-Glucose Cotransporter 2 Inhibitor Therapy.
Khaznadar, Farah; Petrovic, Ana; Khaznadar, Omar; Roguljic, Hrvoje; Bojanic, Kristina; Kuna Roguljic, Lucija; Siber, Stjepan; Smolic, Robert; Bilic-Curcic, Ines; Wu, George Y; Smolic, Martina Journal of clinical medicine 2023 Oct;12(20):
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Primary Hepatic Extra-gastrointestinal Stromal Tumors: Molecular Pathogenesis, Immunohistopathology, and Treatment.
Becker, Erica C; Ozcan, Gonca; Wu, George Y Journal of clinical and translational hepatology 2023 Aug;11(4):942-948
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Primary Non-HFE Hemochromatosis: A Review.
Turshudzhyan, Alla; Wu, David C; Wu, George Y Journal of clinical and translational hepatology 2023 Aug;11(4):925-931
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Seronegative Autoimmune Hepatitis.
Bhumi, Sriya A; Wu, George Y Journal of clinical and translational hepatology 2023 Apr;11(2):459-465
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Immunotherapy-induced Hepatotoxicity: A Review.
Da Cunha, Teresa; Wu, George Y; Vaziri, Haleh Journal of clinical and translational hepatology 2022 Dec;10(6):1194-1204
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Therapeutic Perspectives of IL1 Family Members in Liver Diseases: An Update.
Curcic, Ines Bilic; Kizivat, Tomislav; Petrovic, Ana; Smolic, Robert; Tabll, Ashraf; Wu, George Y; Smolic, Martina Journal of clinical and translational hepatology 2022 Dec;10(6):1186-1193
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Targeted Mitochondrial Delivery to Hepatocytes: A Review.
Heineman, Brent D; Liu, Xiaocong; Wu, George Y Journal of clinical and translational hepatology 2022 Apr;10(2):321-328
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Persistently Rising Alpha-fetoprotein in the Diagnosis of Hepatocellular Carcinoma: A Review.
Turshudzhyan, Alla; Wu, George Y Journal of clinical and translational hepatology 2022 Feb;10(1):159-163
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Drug-induced Fatty Liver Disease: Pathogenesis and Treatment
Tea Omanovic Kolaric, Vjera Nincevic, Lucija Kuna, Kristina Duspara, Kristina Bojanic, Sonja Vukadin, Nikola Raguz-Lucic, George Y Wu, Martina Smolic J Clin Transl Hepatol 2021 Oct;9(5):731-737
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Novel Agents in the Management of Hepatic Encephalopathy: A Review
Leen Z Hasan, George Y Wu J Clin Transl Hepatol 2021 Oct;9(5):749-759
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HBV-HCV Coinfection: Viral Interactions, Management, and Viral Reactivation.
Mavilia, Marianna G; Wu, George Y Journal of clinical and translational hepatology 2018 Sep;6(3):296-305
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Occult Hepatitis C Virus Infection: A Review.
Austria, Alyssa; Wu, George Y Journal of clinical and translational hepatology 2018 Jun;6(2):155-160
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Hepatitis caused by herpes group viruses: A review.
Noor Arish, Panwala Amruta, Forouhar Faripour, Wu George Y Journal of digestive diseases 2018 Jun;19446-455
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Chylous Ascites: A Review of Pathogenesis, Diagnosis and Treatment.
Bhardwaj, Richa; Vaziri, Haleh; Gautam, Arun; Ballesteros, Enrique; Karimeddini, David; Wu, George Y Journal of clinical and translational hepatology 2018 Mar;6(1):105-113
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Mechanisms and Prevention of Vertical Transmission in Chronic Viral Hepatitis.
Mavilia, Marianna G; Wu, George Y Journal of clinical and translational hepatology 2017 Jun;5(2):119-129
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Vascular Diseases of the Spleen: A Review.
Uy, Pearl Princess D; Francisco, Denise Marie; Trivedi, Anshu; O'Loughlin, Michael; Wu, George Y Journal of clinical and translational hepatology 2017 Jun;5(2):152-164
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Dermatologic Extrahepatic Manifestations of Hepatitis C.
Dedania, Bhavtosh; Wu, George Y Journal of clinical and translational hepatology 2015 Jun;3(2):127-33
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A review of methotrexate-associated hepatotoxicity.
Bath, Roopjeet K; Brar, Navkiran K; Forouhar, Faripour A; Wu, George Y Journal of digestive diseases 2014 Aug;15(10):517-24
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Intra-abdominal complications of sarcoidosis.
MacArthur, Kristin Loening; Forouhar, Faripour; Wu, George Yung-Hsing Journal of the Formosan Medical Association = Taiwan yi zhi 2010 Jul;109(7):484-92
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Eosinophilic Digestive Diseases: Eosinophilic Esophagitis, Gastroenteritis, and Colitis
Shifflet A., Forouhar F., Wu G.Y. Journal of the Formosan Medical Association 2009 Jan;108(11):834-843
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Nonalcoholic fatty liver disease and low-carbohydrate diets.
York, Linda Wasserbach; Puthalapattu, Swathy; Wu, George Y Annual review of nutrition 2009 Jan;29365-79
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Non-alcoholic steatohepatitis: an overview.
Shifflet, Allison; Wu, George Y Journal of the Formosan Medical Association = Taiwan yi zhi 2009 Jan;108(1):4-12
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Prospects for future therapy of HCV infection
Sakamoto N., Wu G.Y. Future Virology 2009 Jan;4(5):453-462
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Potential role of RNAi in the treatment of HCV infection.
Volarevic, Martina; Smolic, Robert; Wu, Catherine H; Wu, George Y Expert review of anti-infective therapy 2007 Oct;5(5):823-31
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Drug evaluation: Albuferon-alpha--an antiviral interferon-alpha/albumin fusion protein.
Chemmanur, Annie T; Wu, George Y Current opinion in investigational drugs (London, England : 2000) 2006 Aug;7(8):750-8
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Potential applications of siRNA in hepatitis C virus therapy.
Smolic, Robert; Volarevic, Martina; Wu, Catherine H; Wu, George Y Current opinion in investigational drugs (London, England : 2000) 2006 Feb;7(2):142-6
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Autoimmune hepatitis triggered by statins
Alla V., Abraham J., Siddiqui J., Raina D., Wu G.Y., Chalasani N.P., Bonkovsky H.L. Journal of Clinical Gastroenterology 2006 Jan;40(8):757-761
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Novel delivery methods for treatment of viral hepatitis: an update.
Virovic, Lucija; Wu, Catherine H; Konishi, Masayoshi; Wu, George Y Expert opinion on drug delivery 2005 Jul;2(4):707-17
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Cell culture and animal models for human viral hepatitis
Olive D.S., Konishi M., Wu G.Y. Hepatology Research 2004 Jan;28(2):61-67
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Structure-based design of hepatitis C virus inhibitors.
Smith, R M; Wu, G Y Journal of viral hepatitis 2003 Nov;10(6):405-12
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Extrahepatic manifestations of chronic hepatitis C
Remoroza R., Wu G.Y. Chinese Journal of Digestive Diseases 2003 Jan;4(3):93-99
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Prokinetic therapy for gastroenterological diseases
Maier I., Wu G.Y. Chinese Journal of Digestive Diseases 2003 Jan;4(4):151-159
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Hepatitis C and HIV co-infection: a review.
Maier, Irena; Wu, George Y World journal of gastroenterology 2002 Aug;8(4):577-9
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Gene therapy for metabolic diseases of the liver
Promrat K., Wu G.Y., Wu C.H. BioDrugs 2000 Jan;13(3):177-188
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Gene therapy of hepatic diseases: prospects for the new millennium.
Shetty, K; Wu, G Y; Wu, C H Gut 2000 Jan;46(1):136-9
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Hepatic Fibrosis - A Mini Review
Wu, CH. and Wu, GY. Chinese J Gastro 2000 Jan;580-83
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Schistosomiasis: Progress and problems
Wu G.Y., Halim M.H. World Journal of Gastroenterology 2000 Jan;6(1):12-19
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Hepatocyte-directed gene delivery by receptor-mediated endocytosis.
Smith, R M; Wu, G Y Seminars in liver disease 1999 Jan;19(1):83-92
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Pre-clinical trials using hepatic gene delivery.
Wu, GY; Grove, RI Advanced drug delivery reviews 1998 Mar;30(1-3):199-204
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Liver-selective DNA targeting using the asialoglycoprotein receptor
Ruiz J., Wu G.Y. Biogenic Amines 1998 Jan;14(5):499-518
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Receptor-mediated delivery of foreign genes to hepatocytes
Wu G.Y., Wu C.H. Advanced Drug Delivery Reviews 1998 Jan;29(3):243-248
-
Targeted therapy for viral hepatitis
Schuster M.J., Wu G.Y. Drugs of Today 1996 Jan;32(8):653-661
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Prospects of therapy of liver diseases with foreign genes.
Kormis, K K; Wu, G Y Seminars in liver disease 1995 Aug;15(3):257-67
-
Hepatocellular carcinoma: update on diagnosis and treatment.
Ramsey, W H; Wu, G Y Digestive diseases (Basel, Switzerland) 1995 Jan;13(2):81-91
-
Gene therapy: applications to the treatment of gastrointestinal and liver diseases.
Chang, A G; Wu, G Y Gastroenterology 1994 Apr;106(4):1076-84
-
Therapeutic implications of delivery and expression of foreign genes in hepatocytes.
Grasso, A W; Wu, G Y Advances in pharmacology (San Diego, Calif.) 1994 Jan;28169-92
-
Liver-directed gene delivery
Wu G.Y., Wu C.H. Advanced Drug Delivery Reviews 1993 Jan;12(3):159-167
-
Strategies for gene therapy in the liver.
Versland, M R; Wu, C H; Wu, G Y Seminars in liver disease 1992 Aug;12(3):332-9
-
Methods of gene transfer into hepatocytes: progress toward gene therapy.
Makdisi, W J; Wu, C H; Wu, G Y Progress in liver diseases 1992 Jan;101-24
-
Delivery systems for gene therapy.
Wu, G Y; Wu, C H Biotherapy (Dordrecht, Netherlands) 1991 Jan;3(1):87-95
-
Receptor-mediated protection of normal hepatocytes during chemotherapy for hepatocellular carcinoma.
Keegan-Rogers, V; Wu, C H; Wu, G Y Targeted diagnosis and therapy 1991 Jan;4105-25
-
Targeted delivery and expression of foreign genes in hepatocytes.
Wu, G Y; Wu, C H Targeted diagnosis and therapy 1991 Jan;4127-49
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Short Surveys
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ALN-RSV01: siRNA targeting RSV nucleocapsid N gene treatment of RSV infection
Devuni D., Wu G.Y. Drugs of the Future 2009 Jan;34(10):781-783
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Research advances in the development of peptide antibiotics.
Rossi, Lisa M; Rangasamy, Priya; Zhang, Jie; Qiu, Xiao-Qing; Wu, George Y Journal of pharmaceutical sciences 2008 Mar;97(3):1060-70
| Title or Abstract | Type | Sponsor/Event | Date/Year | Location |
|---|---|---|---|---|
| The Molecular and Clinical Bases of Anti-HCV Drug ResistanceThe Molecular and Clinical Bases of Anti-HCV Drug Resistance | Plenary Lecture | Egyptian Society of Updates in Hepatology and Gastroenterology | 2017 | Cairo, Egypt |
| “Eosinophilic Esophagitis” | Lecture | Medical Grand Rounds | 2016 | Manchester Memorial Hospital |
| “Up and Down the GI Tract- A Update” | Lecture | Interstate Physicians Medical Association | 2016 | San Antonio, TX |
| “Wilson’s Disease” | Lecture | Medical Grand Rounds | 2016 | Manchester Hospital |
| "HCV Update" | Lecture | Medical Grand Rounds | 2016 | Rockville General Hospital |
| “Complications of Chronic Liver Disease” | Lecture | University of New England College of Osteopathic Medicine | 2016 | Manchester Memorial Hospital |
| “Acute Hepatitis” | Lecture | Resident’s Noon Lecture | 2016 | UCONN |
| “The Molecular Basis of HCV Resistance to Antiviral Agents” | Lecture | International Forum on Hepatitis | 2016 | Cairo, Egypt |
| “Clinical Evidence of HCV GT-1 Resistance to Antiviral Agents” | Plenary Lecture | International Forum on Hepatitis | 2016 | Cairo, Egypt |
| ”Autoimmune Hepatitis” | Lecture | Medical Grand Rounds | 2016 | Manchester Memorial Hospital |
| ”Autoimmune Hepatitis” | Lecture | Medical Grand Rounds | 2016 | Rockville General Hospital |
| “Chronic Viral Hepatitis: What is it and why does it matter?” | Lecture | Mini-Medical Program | 2016 | UCONN |
| “Serum Liver Tests” | Lecture | University of New England College of Osteopathic Medicine | 2016 | Manchester Memorial Hospital |
| “Iron in Health and Disease” | Lecture | UCONN 1st y Medical Students | 2016 | UCONN |
| “What Makes a Good Research Project: An Editor's Perspective Faculty of Medicine” | Lecture | Faculty of Medicine, University of Osijek | 2016 | Osijek, Croatia |
| “Mentor and Teacher: What’s the Difference?” | Lecture | Faculty of Medicine, University of Osijek | 2016 | Osijek, Croatia |
| “The MD-PHD Program: A Personal Experience” | Lecture | Faculty of Medicine, University of Osijek | 2016 | Osijek, Croatia |
| “Publication of Medical Articles: Strategies for Success” | Lecture | Faculty of Medicine, University of Osijek | 2016 | Osijek, Croatia |
| “Workshop on actual manuscripts” | Lecture | Faculty of Medicine, University of Osijek | 2016 | Osijek, Croatia |
| “C. Difficile Colitis and the Gut Microbiome” | Lecture | Medical Grand Rounds | 2016 | Rockville General Hospital |
| “Hepatitis A, D, and E” | Lecture | University of New England College of Osteopathic Medicine | 2016 | Manchester Memorial Hospital |
| “Introduction of Gastroenterology” “Chronic Viral Hepatitis” “Endoscopy”* | Lecture | UCONN Pre-Med Course | 2016 | UCONN |
| “C. difficile Colitis and the Gut Microbiome” | Lecture | Medical Grand Rounds | 2016 | Manchester Memorial Hospital |
| “Fulminant Hepatic Failure” | Lecture | University of New England College of Osteopathic Medicine | 2016 | Manchester Hospital |
| “Strategies for Publishing Medical Articles in English Journals” | Lecture | JiLin University | 2016 | JiLin, China |
| “Targeted Transplantation of Mitochondria to Hepatocytes” | Lecture | JiLin University | 2016 | JiLin, China |
| “Malabsorption: Clinical Presentation and Diagnostic Tests” | Lecture | Nutrition Department, Saint Joseph’s University | 2016 | West Hartford, CT |
| “Celiac Disease” | Lecture | Nutrition Department, Saint Joseph’s University | 2016 | West Hartford, CT |
| “Update on HCV Treatment” | Plenary Lecture | Third Annual International Monothematic Conference on Hepatitis C | 2016 | Orahovica, Croatia |
| “Brief Update on HCV Treatment” | Lecture | UCONN HCV Support Group | 2016 | UCONN |
| “Non-Alcoholic Liver Disease” | Lecture | Interstate Physicians Medical Association | 2016 | San Antonio, TX |
| "Meet the Professor" | Talk | Interstate Physicians Medical Association | 2016 | San Antonio, TX |
| “The Molecular and Clinical Bases for Anti-HCV Drug Resistance “ | Lecture | Third Annual International Monothematic Conference on Hepatitis C | 2016 | Orahovica, Croatia |
| “Imaging of Hepatic Lesions” | Lecture | Medical Grand Rounds | 2016 | Manchester Memorial Hospital |
| “Teachers versus Mentors: What’s the Difference” | Lecture | Mentorship Course Faculty of Medicine, University of Osijek | 2016 | Osijek, Croatia |
| “Strategies for Publication of Medical Articles” | Lecture | Mentorship Course Faculty of Medicine, University of Osijek | 2016 | Osijek, Croatia |
| “Imaging of Hepatic Lesions” | Lecture | Medical Grand Rounds | 2016 | Rockville General Hospital |
| “Pathogenesis and Treatment of Ascites” | Lecture | University of New England College of Osteopathic Medicine | 2015 | Manchester Memorial Hospital |
| “Update on the Pathogenesis and Treat- ment of Hemochromatosis” | Lecture | Endocrine Intercity Grand Rounds/UCONN | 2015 | UCONN |
| “Update on the Pathogenesis and Treatment of HCV” | Lecture | Advances in Internal Medicine | 2015 | UCONN |
| "Methotrexate Hepatotoxicity" | Lecture | Medical Grand Rounds | 2015 | Manchester Memorial Hospital |
| "Methotrexate Hepatotoxicity" | Lecture | Medical Grand Rounds | 2015 | Rockville General Hospital |
| “A Practical Immunocompetent Animal Model of Hepatitis C Viral Infection” | Lecture | Department of Nutritional Sciences | 2015 | UCONN Storrs, CT |
| "Digestive Diseases Mediated by Bacterial Toxins” | Lecture | Medical Microbiology Course | 2015 | Misr International University, Cairo, Egypt |
| "Update on the Pathogenesis and Treatment of HCV" | Lecture | Medical Microbiology Course, School of Pharmacy | 2015 | Misr International University, Cairo, Egypt |
| “Digestive Diseases Caused by Helminths” | Lecture | Medical Microbiology Course, School of Pharmacy | 2015 | Misr International University, Cairo, Egypt |
| “Viral Hepatitis” | Lecture | Medical Microbiology Course, School of Pharmacy | 2015 | Misr International University, Cairo, Egypt |
| “Chronic Viral Hepatitis: What is it and why is it important” | Lecture | Mini-Medical Program | 2015 | UCONN |
| “Update on the pathogenesis, and treatment of HCV” | Lecture | The 22nd Annual GI Symposium Update on the Management of Common GI, Pancrea | 2015 | Rutgers, Robert Wood Johnson School of Medicine New Brunswick, NJ |
| "Wilson’s Disease" | Lecture | Medical Grand Rounds | 2015 | Rockville General Hospital |
| “Viral Hepatitis” | Lecture | American Liver Foundation Clinical Treatment Initiative | 2015 | Rushford Treatment Center Middletown, CT |
| “Iron in Health and Disease” | Lecture | OS3, 2y Medical Students | 2015 | UCONN |
| Targeted Transplantation of Mitochondria to Specific Cell Types” | Lecture | Lunch and Learn, Alexion, Corp. Cheshire, CT | 2015 | Cheshire, CT |
| “Update on HBV” | Lecture | GI Fellows Lecture | 2015 | UCONN |
| “PEG-tubes” | Lecture | GI Fellows’ Lecture Series | 2015 | UCONN |
| Foreign Body Ingestion” | Lecture | Medical Grand Rounds | 2015 | Manchester Memorial Hospital |
| ”Foreign Body Ingestion” | Lecture | Medical Grand Rounds | 2015 | Rockville General Hospital |
| “Update on HCV Treatment” | Lecture | HCV Support Group | 2015 | UCONN |
| “Hepatitis C Therapy: Current Status and Future Challenges” | Lecture | Second Annual International Monothematic Conference on Hepatitis C | 2015 | Lug, Croatia |
| “Extrahepatic Manifestations of Hepatitis C” | Lecture | Second Annual International Monothematic Conference on Hepatitis C | 2015 | Lug, Croatia |
| “Structural Analogs for Inhibition of HCV Replication” | Lecture | Second Annual International Monothematic Conference on Hepatitis C | 2015 | Lug, Croatia |
| “What Makes a Good Clinical Research Paper?” An Editor's Perspective” | Lecture | First International Summit on Medical Research and Publication | 2015 | Wuhan, China |
| “Rescue of Hepatocytes from Lethal Mitochondrial Damage by Targeted Transplantation of Mitochondria” | Talk | American Association for the Study of Liver Diseases | 2015 | San Francisco, CA |
| “Pathogenesis and Treatment of Ascites” | Lecture | University of New England College of Osteopathic Medicine | 2015 | Manchester Memorial Hospital |