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Bone marrow neutrophil aging in sickle cell disease mice is associated with impaired osteoblast functions.
Rana, Kavita; Pantoja, Kimberly; Xiao, Liping Biochemistry and biophysics reports 2018 Dec;16110-114
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FGF2 crosstalk with Wnt signaling in mediating the anabolic action of PTH on bone formation.
Xiao, Liping; Fei, Yurong; Hurley, Marja M Bone reports 2018 Dec;9136-144
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Ablation of low-molecular-weight FGF2 isoform accelerates murine osteoarthritis while loss of high-molecular-weight FGF2 isoforms offers protection.
Burt, Patience M; Xiao, Liping; Doetschman, Thomas; Hurley, Marja M Journal of cellular physiology 2018 Aug;2344418-4431
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FGF23 regulates Wnt/β-catenin signaling-mediated osteoarthritis in mice overexpressing high molecular weight FGF2.
Meo Burt, Patience; Xiao, Liping; Hurley, Marja M Endocrinology 2018 Apr;1592386-2396
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FGF23 Neutralizing Antibody Partially Improves Bone Mineralization Defect of HMWFGF2 Isoforms Transgenic Female Mice.
Xiao, Liping; Homer-Bouthiette, Collin; Hurley, Marja M Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2018 Mar;331347-1361
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Inhibition of FGFR Signaling Partially Rescues Hypophosphatemic Rickets in HMWFGF2 Tg Male Mice.
Xiao, Liping; Du, Erxia; Homer-Bouthiette, Collin; Hurley, Marja M Endocrinology 2017 Oct;158(10):3629-3646
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Clinically Relevant Concentrations of Ketamine Inhibit Osteoclast Formation In Vitro in Mouse Bone Marrow Cultures.
Du, Erxia; McAllister, Patrick; Venna, Venugopal Reddy; Xiao, Liping Journal of cellular biochemistry 2016 Oct;118914-923
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FGF2 High Molecular Weight Isoforms Contribute to Osteoarthropathy in Male Mice.
Burt, Patience Meo; Xiao, Liping; Dealy, Caroline; Fisher, Melanie C; Hurley, Marja M Endocrinology 2016 Oct;1574602-4614
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FGF23 Neutralizing Antibody Ameliorates Hypophosphatemia and Impaired FGF Receptor Signaling in Kidneys of HMWFGF2 Transgenic Mice.
Du, E; Xiao, L; Hurley, M M Journal of cellular physiology 2016 Jun;232610-616
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Loss of Bone in Sickle Cell Trait and Sickle Cell Disease Female Mice Is Associated with Reduced IGF-1 in Bone and Serum.
Xiao, Liping; Andemariam, Biree; Taxel, Pam; Adams, Douglas J; Zempsky, William T; Hurley, Marja M Endocrinology 2016 May;1573036-46
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FGFR Inhibitor Ameliorates Hypophosphatemia and Impaired Engrailed-1/Wnt Signaling in FGF2 High Molecular Weight Isoform Transgenic Mice.
Du, Erxia; Xiao, Liping; Hurley, Marja M Journal of cellular biochemistry 2016 Jan;1171991-2000
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Age-Related Changes in FGF-2, Fibroblast Growth Factor Receptors and β-Catenin Expression in Human Mesenchyme-Derived Progenitor Cells.
Hurley, Marja M; Gronowicz, Gloria; Zhu, Li; Kuhn, Liisa T; Rodner, Craig; Xiao, Liping Journal of cellular biochemistry 2015 Sep;117721-9
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Accelerated Fracture Healing in Transgenic Mice Overexpressing an Anabolic Isoform of Fibroblast Growth Factor 2.
Hurley, Marja M; Adams, Douglas J; Wang, Liping; Jiang, Xi; Meo Burt, Patience; Du, Erxia; Xiao, Liping Journal of cellular biochemistry 2015 Aug;117599-611
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Knockout of nuclear high molecular weight FGF2 isoforms in mice modulates bone and phosphate homeostasis.
Homer-Bouthiette, Collin; Doetschman, Thomas; Xiao, Liping; Hurley, Marja M The Journal of biological chemistry 2014 Nov;289(52):36303-14
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Fibroblast growth factor-2 isoform (low molecular weight/18 kDa) overexpression in preosteoblast cells promotes bone regeneration in critical size calvarial defects in male mice.
Xiao, Liping; Ueno, Daisuke; Catros, Sylvain; Homer-Bouthiette, Collin; Charles, Lyndon; Kuhn, Liisa; Hurley, Marja M Endocrinology 2014 Jan;155(3):965-74
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FGF-2 enhances Runx-2/Smads nuclear localization in BMP-2 canonical signaling in osteoblasts.
Agas, Dimitrios; Sabbieti, Maria Giovanna; Marchetti, Luigi; Xiao, Liping; Hurley, Marja M Journal of cellular physiology 2013 Nov;228(11):2149-58
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BMP-2 differentially modulates FGF-2 isoform effects in osteoblasts from newborn transgenic mice.
Sabbieti, Maria Giovanna; Agas, Dimitrios; Marchetti, Luigi; Coffin, J Douglas; Xiao, Liping; Hurley, Marja M Endocrinology 2013 Aug;154(8):2723-33
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Nuclear fibroblast growth factor 2 (FGF2) isoforms inhibit bone marrow stromal cell mineralization through FGF23/FGFR/MAPK in vitro.
Xiao, Liping; Esliger, Alycia; Hurley, Marja M Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Jan;28(1):35-45
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Fibroblast growth factor 2 stimulation of osteoblast differentiation and bone formation is mediated by modulation of the Wnt signaling pathway.
Fei, Yurong; Xiao, Liping; Doetschman, Thomas; Coffin, Douglas J; Hurley, Marja M The Journal of biological chemistry 2011 Nov;286(47):40575-83
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The impaired bone anabolic effect of PTH in the absence of endogenous FGF2 is partially due to reduced ATF4 expression.
Fei, Yurong; Xiao, Liping; Hurley, Marja M Biochemical and biophysical research communications 2011 Aug;412(1):160-4
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Disruption of the Fgf2 gene activates the adipogenic and suppresses the osteogenic program in mesenchymal marrow stromal stem cells.
Xiao, Liping; Sobue, Takanori; Esliger, Alycia; Kronenberg, Mark S; Coffin, J Douglas; Doetschman, Thomas; Hurley, Marja M Bone 2010 Aug;47(2):360-70
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Signaling pathways implicated in PGF2alpha effects on Fgf2+/+ and Fgf2-/- osteoblasts.
Sabbieti, Maria Giovanna; Agas, Dimitrios; Marchetti, Luigi; Santoni, Giorgio; Amantini, Consuelo; Xiao, Liping; Menghi, Giovanna; Hurley, Marja M Journal of cellular physiology 2010 Aug;224(2):465-74
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Nuclear isoforms of fibroblast growth factor 2 are novel inducers of hypophosphatemia via modulation of FGF23 and KLOTHO.
Xiao, Liping; Naganawa, Takahiro; Lorenzo, Joseph; Carpenter, Thomas O; Coffin, J Douglas; Hurley, Marja M The Journal of biological chemistry 2010 Jan;285(4):2834-46
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Fibroblast growth factor 2 positively regulates expression of activating transcription factor 4 in osteoblasts.
Fei, Yurong; Xiao, Liping; Hurley, Marja M Biochemical and biophysical research communications 2010 Jan;391(1):335-9
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Exported 18-kDa isoform of fibroblast growth factor-2 is a critical determinant of bone mass in mice.
Xiao, Liping; Liu, Peng; Li, Xiaofeng; Doetschman, Thomas; Coffin, J Douglas; Drissi, Hicham; Hurley, Marja M The Journal of biological chemistry 2009 Jan;284(5):3170-82
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Reduced expression and function of bone morphogenetic protein-2 in bones of Fgf2 null mice.
Naganawa, Takahiro; Xiao, Liping; Coffin, J D; Doetschman, Thomas; Sabbieti, Maria Giovanna; Agas, Dimitrios; Hurley, Marja M Journal of cellular biochemistry 2008 Apr;103(6):1975-88
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Impaired bone anabolic response to parathyroid hormone in Fgf2-/- and Fgf2+/- mice.
Hurley, M M; Okada, Y; Xiao, L; Tanaka, Y; Ito, M; Okimoto, N; Nakamura, T; Rosen, C J; Doetschman, T; Coffin, J D Biochemical and biophysical research communications 2006 Mar;341(4):989-94
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Over-expression of fibroblast growth factor-2 causes defective bone mineralization and osteopenia in transgenic mice.
Sobue, T; Naganawa, T; Xiao, L; Okada, Y; Tanaka, Y; Ito, M; Okimoto, N; Nakamura, T; Coffin, J D; Hurley, M M Journal of cellular biochemistry 2005 May;95(1):83-94
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Stat1 controls postnatal bone formation by regulating fibroblast growth factor signaling in osteoblasts.
Xiao, Liping; Naganawa, Takahiro; Obugunde, Eneze; Gronowicz, Gloria; Ornitz, David M; Coffin, J Douglas; Hurley, Marja M The Journal of biological chemistry 2004 Jun;279(26):27743-52
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Effect of overexpressing fibroblast growth factor 2 protein isoforms in osteoblastic ROS 17/2.8 cells.
Xiao, L; Liu, P; Sobue, T; Lichtler, A; Coffin, J D; Hurley, M M Journal of cellular biochemistry 2003 Aug;89(6):1291-301
