UCONN

HEALTH

Photo of Siu-Pok  Yee, Ph.D.

Siu-Pok Yee, Ph.D.

Assistant Professor, Cell Biology
Academic Office Location:
Cell Biology
UConn Health
263 Farmington Avenue
EB-010
Farmington, CT 06030
Phone: 860-679-3726
Fax: 860 679-1846
Email: syee@uchc.edu
Website(s):

Gene Targeting and Transgenic Facility

Department of Cell Biology

Cell Biology Graduate Program

1. To provide consultation, expertise and collaboration with investigators to develop unique mouse strains and provide support in the management of these mouse strains for their research programs.

2. To provide comprehensive services to generate genetically modified mouse strains using state-of-the-art technology.

3. To develop novel and state-of-the-art technology in manipulation of the mouse genome and generation of novel mouse strains.

Specialties include molecular biology, mouse genetics and mouse developmental biology.

Education
DegreeInstitutionMajor
B.Sc.McMaster UniversityBiochemistry
M.Sc.McMaster UniversityMedical Sciences
Ph.D.McMaster UniversityMedical Sciences

Post-Graduate Training
TrainingInstitutionSpecialty
PostdoctoralMount Sinai Hospital Research InstitutePostdoctoral Fellow in the Division of Developmental & Molecular Biology under Dr. Alan Bernstein and Dr. Tony Pawson. Project: Introduction of new oncogenes into hematopoietic stem cells and mouse germline
PostdoctoralNational Institute for Medical ResearchPostdoctoral Fellow in the Laboratory of Eukaryotic Molecular Genetics under Dr. Peter W.J. Rigby. Project: Regulation of transcription during somitogenesis in early mouse embryos.

Not accepting students for lab rotations at this time

Journal Articles

Book Chapters

  • Transgenic animals
    Yee S-P Methods in Renal Toxicology 1996 Jan;413-426
  • Transforming proteins of human adenoviruses
    Branton PE, Rowe DT, Yee S-P, Tremblay ML & Graham FL Genes and Cancer 1985 Jan;339-350

Conference Papers

  • Characterization of functional elements in the NF1 promoter.
    Yee SP 2002 Jan;
  • Transcriptional regulation of NF1 gene expression.
    Yee SP 2002 Jan;
  • Analysis of human prolactin decidual-specific gene expression in transgenic mice.
    Yee SP 1999 Jan;
  • Control of myogenesis and muscle regeneration.
    Yee SP 1998 Jan;
  • Genetics and molecular biology methodology.
    Yee SP 1998 Jan;
  • Transgenic mice for studies of transcriptional control and differentiation.
    Yee SP 1998 Jan;
  • Human sex hormone-binding globulin gene expression in transgenic mice.
    Yee SP 1996 Jan;
  • The regulation of Myf5 expression during mouse embryogenesis.
    Yee SP 1995 Jan;
  • The regulation of myogenin gene expression during the embryonic development of the mouse.
    Yee SP 1993 Jan;
  • The regulation of myogenin expression.
    Yee SP 1992 Jan;
  • Expression of the gene encoding a 14 kd lectin during somite development in the mouse.
    Yee SP 1990 Jan;
  • Regulation of transcription during early mouse embryogenesis.
    Yee SP 1989 Jan;
  • Neoplastic and cardiovascular disorder in transgenic mice expressing the v-fps protein kinase.
    Yee SP 1988 Jan;
  • Analysis of cellular proteins associated with Ad5 E1A products.
    Yee SP 1986 Jan;
  • Analysis of adenovirus type 5 early region 1 proteins.
    Yee SP 1985 Jan;
  • Characterization of the adenovirus type 5 176R protein using anti-peptide sera.
    Yee SP 1985 Jan;
  • Analysis of Ad5 E1 proteins using anti-peptide sera.
    Yee SP 1984 Jan;
  • Lack of complementation between Ad5 mutants and mouse cell lines constitutively expressing the ICP4 immediate early gene of HSV-1.
    Yee SP 1984 Jan;
  • Analysis of human adenovirus early region 1 polypeptides using antisera against synthetic peptides.
    Yee SP 1983 Jan;
  • Characterization of human Ad5 E1 proteins using antisera against synthetic peptides.
    Yee SP 1983 Jan;
  • Studies on the early region 1 proteins of human adenovirus type 5 using synthetic peptides.
    Yee SP 1983 Jan;
  • Identification of E1 polypeptides of adenovirus type 5 using a serum directed against the predicted carboxy termini.
    Yee SP 1982 Jan;
  • Phosphorylation of the E1B 58K antigen of adenovirus type 5.
    Yee SP 1982 Jan;
  • Further studies on protein kinase activity association with early Ad5 viral antigens.
    Yee SP 1980 Jan;
  • Protein kinase activity associated with the tumor antigens of human adenoviruses.
    Yee SP 1980 Jan;
  • Endogenous protein kinase at the external surface of normal and RSV-transformed chick cells.
    Yee SP 1979 Jan;