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Signaling pathways associated with Lgr6 to regulate osteogenesis.
King, Justin S; Wan, Matthew; Wagley, Yadav; Stestiv, Marta; Kalajzic, Ivo; Hankenson, Kurt D; Sanjay, Archana Bone 2024 Oct;187117207
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Wnt-associated adult stem cell marker Lgr6 is required for osteogenesis and fracture healing.
Doherty, Laura; Wan, Matthew; Peterson, Anna; Youngstrom, Daniel W; King, Justin S; Kalajzic, Ivo; Hankenson, Kurt D; Sanjay, Archana Bone 2023 Jan;169116681
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PDGF inhibits BMP2-induced bone healing.
Novak, Sanja; Madunic, Josip; Shum, Laura; Vucetic, Milan; Wang, Xi; Tanigawa, Hitoshi; Ghosh, Mallika; Sanjay, Archana; Kalajzic, Ivo NPJ Regenerative medicine 2023 Jan;8(1):3
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Interactions of B-lymphocytes and bone cells in health and disease.
Grcevic, Danka; Sanjay, Archana; Lorenzo, Joseph Bone 2021 Dec;116296
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Diabetes impairs periosteal progenitor regenerative potential.
Doherty, Laura; Wan, Matthew; Kalajzic, Ivo; Sanjay, Archana Bone 2020 Nov;115764
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LGRs in Skeletal Tissues: An Emerging Role for Wnt-Associated Adult Stem Cell Markers in Bone.
Doherty, Laura; Sanjay, Archana JBMR plus 2020 Jul;4(7):e10380
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Investigating global gene expression changes in a murine model of cherubism.
Sharma, Tulika; Cotney, Justin; Singh, Vijender; Sanjay, Archana; Reichenberger, Ernst J; Ueki, Yasuyoshi; Maye, Peter Bone 2020 Mar;135115315
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Cbl-PI3K interaction regulates Cathepsin K secretion in osteoclasts.
Yu, Jungeun; Adapala, Naga Suresh; Doherty, Laura; Sanjay, Archana Bone 2019 Jul;127376-385
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Protease-Activated Receptor 1 Deletion Causes Enhanced Osteoclastogenesis in Response to Inflammatory Signals through a Notch2-Dependent Mechanism.
Jastrzebski, Sandra; Kalinowski, Judith; Mun, Sehwan; Shin, Bongjin; Adapala, Naga Suresh; Jacome-Galarza, Christian E; Mirza, Faryal; Aguila, H Leonardo; Drissi, Hicham; Sanjay, Archana; Canalis, Ernesto; Lee, Sun-Kyeong; Lorenzo, Joseph A Journal of Immunology (Baltimore, Md. : 1950) 2019 Jul;203(1):105-116
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PI3K activation increases SDF-1 production and number of osteoclast precursors, and enhances SDF-1-mediated osteoclast precursor migration.
Adapala, Naga Suresh; Root, Sierra; Lorenzo, Joseph; Aguila, Hector; Sanjay, Archana Bone reports 2019 Jun;10100203
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PDGF Modulates BMP2-Induced Osteogenesis in Periosteal Progenitor Cells.
Wang, Xi; Matthews, Brya G; Yu, Jungeun; Novak, Sanja; Grcevic, Danka; Sanjay, Archana; Kalajzic, Ivo JBMR plus 2019 May;3(5):e10127
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A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing.
Doherty, Laura; Yu, Jungeun; Wang, Xi; Hankenson, Kurt D; Kalajzic, Ivo; Sanjay, Archana PloS one 2019 Jan;14(10):e0223846
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Induction of the Hajdu Cheney Syndrome Mutation in CD19 B Cells in Mice Alters B-Cell Allocation but Not Skeletal Homeostasis
Yu, Jungeun; Zanotti, Stefano; Schilling, Lauren; Schoenherr, Chris; Economides, Aris; Sanjay, Archana; Canalis, Ernesto The American Journal of Pathology 2018 Mar;188(6):1430-1446
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A novel role for cathepsin K in periosteal osteoclast precursors during fracture repair.
Walia, Bhavita; Lingenheld, Elizabeth; Duong, Le; Sanjay, Archana; Drissi, Hicham Annals of the New York Academy of Sciences 2018 Feb;141557-68
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The Hajdu Cheney Mutation is a Determinant of B Cell Allocation of the Splenic Marginal Zone
Yu, Jungeun; Zanotti, Stefano; Walia, Bhavita; Jellison, Evan; Sanjay, Archana; Canalis, Ernesto The American Journal of Pathology 2017 Oct;188(1):149-159
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Sustained Notch2 Signaling in Osteoblasts, but no in Osteoclasts, is Linked to Osteopenia in a Mouse Model of Hajdu-Cheney Syndrome
Zanotti, Stefano; Yu, Jungeun; Sanjay, Archana; Schilling, Lauren; Schoenherr, Chris; Economides, Aris N; Canalis, Ernesto The Journal of Biological Chemistry 2017 Jun;292(29):12232-12244
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Loss of Cbl-PI3K interaction modulates the periosteal response to fracture by enhancing osteogenic commitment and differentiation.
Scanlon, Vanessa; Walia, Bhavita; Yu, Jungeun; Hansen, Marc; Drissi, Hicham; Maye, Peter; Sanjay, Archana Bone 2016 Nov;95124-135
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Dual growth factor delivery from biofunctionalized allografts: Sequential VEGF and BMP-2 release to stimulate allograft remodeling.
Sharmin, Farzana; McDermott, Casey; Lieberman, Jay; Sanjay, Archana; Khan, Yusuf Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2016 May;351086-1095
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The Multifaceted Osteoclast; Far and Beyond Bone Resorption.
Drissi, Hicham; Sanjay, Archana Journal of cellular biochemistry 2016 Mar;1171753-6
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Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair.
Scanlon, Vanessa; Soung, Do Yu; Adapala, Naga Suresh; Morgan, Elise; Hansen, Marc F; Drissi, Hicham; Sanjay, Archana PloS one 2015 Jan;10(9):e0138194
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Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy.
Adapala, Naga Suresh; Holland, Danielle; Scanlon, Vanessa; Barbe, Mary F; Langdon, Wallace Y; Tsygankov, Alexander Y; Lorenzo, Joseph A; Sanjay, Archana Bone 2014 Jul;671-9
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Establishment of human cell type-specific iPS cells with enhanced chondrogenic potential.
Guzzo, Rosa M; Scanlon, Vanessa; Sanjay, Archana; Xu, Ren-He; Drissi, Hicham Stem cell reviews 2014 Jun;10(6):820-9
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c-Cbl inhibition improves cardiac function and survival in response to myocardial ischemia.
Rafiq, Khadija; Kolpakov, Mikhail A; Seqqat, Rachid; Guo, Jianfen; Guo, Xinji; Qi, Zhao; Yu, Daohai; Mohapatra, Bhopal; Zutshi, Neha; An, Wei; Band, Hamid; Sanjay, Archana; Houser, Steven R; Sabri, Abdelkarim Circulation 2014 May;129(20):2031-43
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Altered hematopoietic stem cell and osteoclast precursor frequency in cathepsin K null mice.
Jacome-Galarza, Christian; Soung, Do Yu; Adapala, Naga Suresh; Pickarski, Maureen; Sanjay, Archana; Duong, Le T; Lorenzo, Joseph A; Drissi, Hicham Journal of cellular biochemistry 2014 Mar;115(8):1449-57
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Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-b.
Adapala, Naga Suresh; Barbe, Mary F; Tsygankov, Alexander Y; Lorenzo, Joseph A; Sanjay, Archana Journal of cellular biochemistry 2014 Jan;115(7):1277-89
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TULA-2, a novel histidine phosphatase, regulates bone remodeling by modulating osteoclast function.
Back, Steven H; Adapala, Naga Suresh; Barbe, Mary F; Carpino, Nick C; Tsygankov, Alexander Y; Sanjay, Archana Cellular and molecular life sciences : CMLS 2013 Apr;70(7):1269-84
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cSrc is necessary for epididymal development and is incorporated into sperm during epididymal transit.
Krapf, Dario; Ruan, Ye Chun; Wertheimer, Eva V; Battistone, Maria A; Pawlak, John B; Sanjay, Archana; Pilder, Stephen H; Cuasnicu, Patricia; Breton, Sylvie; Visconti, Pablo E Developmental biology 2012 Sep;369(1):43-53
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c-Cbl ubiquitin ligase regulates focal adhesion protein turnover and myofibril degeneration induced by neutrophil protease cathepsin G.
Rafiq, Khadija; Guo, Jianfen; Vlasenko, Liudmila; Guo, Xinji; Kolpakov, Mikhail A; Sanjay, Archana; Houser, Steven R; Sabri, Abdelkarim The Journal of biological chemistry 2012 Feb;287(8):5327-39
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Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling.
Buitrago, Lorena; Langdon, Wallace Y; Sanjay, Archana; Kunapuli, Satya P Blood 2011 Nov;118(20):5631-40
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Abrogation of Cbl-PI3K interaction increases bone formation and osteoblast proliferation.
Brennan, Tracy; Adapala, Naga Suresh; Barbe, Mary F; Yingling, Vanessa; Sanjay, Archana Calcified tissue international 2011 Nov;89(5):396-410
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Extracellular engagement of ADAM12 induces clusters of invadopodia with localized ectodomain shedding activity.
Albrechtsen, Reidar; Stautz, Dorte; Sanjay, Archana; Kveiborg, Marie; Wewer, Ulla M Experimental cell research 2011 Jan;317(2):195-209
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The loss of Cbl-phosphatidylinositol 3-kinase interaction perturbs RANKL-mediated signaling, inhibiting bone resorption and promoting osteoclast survival.
Adapala, Naga Suresh; Barbe, Mary F; Langdon, Wallace Y; Nakamura, Mary C; Tsygankov, Alexander Y; Sanjay, Archana The Journal of biological chemistry 2010 Nov;285(47):36745-58
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Src is a major signaling component for CTGF induction by TGF-beta1 in osteoblasts.
Zhang, X; Arnott, J A; Rehman, S; Delong, W G; Sanjay, A; Safadi, F F; Popoff, S N Journal of cellular physiology 2010 Sep;224(3):691-701
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Cbl-b is a novel physiologic regulator of glycoprotein VI-dependent platelet activation.
Daniel, James L; Dangelmaier, Carol A; Mada, Sripal; Buitrago, Lorena; Jin, Jianguo; Langdon, Wallace Y; Tsygankov, Alexander Y; Kunapuli, Satya P; Sanjay, Archana The Journal of biological chemistry 2010 Jun;285(23):17282-91
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Inhibition of Ser/Thr phosphatases induces capacitation-associated signaling in the presence of Src kinase inhibitors.
Krapf, Dario; Arcelay, Enid; Wertheimer, Eva V; Sanjay, Archana; Pilder, Stephen H; Salicioni, Ana M; Visconti, Pablo E The Journal of biological chemistry 2010 Mar;285(11):7977-85
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Cbl-phosphatidylinositol 3 kinase interaction differentially regulates macrophage colony-stimulating factor-mediated osteoclast survival and cytoskeletal reorganization.
Adapala, Naga Suresh; Barbe, Mary F; Langdon, Wallace Y; Tsygankov, Alexander Y; Sanjay, Archana Annals of the New York Academy of Sciences 2010 Mar;1192376-84
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ADAM12 localizes with c-Src to actin-rich structures at the cell periphery and regulates Src kinase activity.
Stautz, Dorte; Sanjay, Archana; Hansen, Matilde Thye; Albrechtsen, Reidar; Wewer, Ulla M; Kveiborg, Marie Experimental cell research 2010 Jan;316(1):55-67
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Lyn, PKC-delta, SHIP-1 interactions regulate GPVI-mediated platelet-dense granule secretion.
Chari, Ramya; Kim, Soochong; Murugappan, Swaminathan; Sanjay, Archana; Daniel, James L; Kunapuli, Satya P Blood 2009 Oct;114(14):3056-63
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Loss of Cbl-b increases osteoclast bone-resorbing activity and induces osteopenia.
Nakajima, Arata; Sanjay, Archana; Chiusaroli, Riccardo; Adapala, Naga Suresh; Neff, Lynn; Itzsteink, Cecile; Horne, William C; Baron, Roland Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009 Jul;24(7):1162-72
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FGFR2-Cbl interaction in lipid rafts triggers attenuation of PI3K/Akt signaling and osteoblast survival.
Dufour, Cécilie; Guenou, Hind; Kaabeche, Karim; Bouvard, Daniel; Sanjay, Archana; Marie, Pierre J Bone 2008 Jun;42(6):1032-9
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Molecular requirements for induction of CTGF expression by TGF-beta1 in primary osteoblasts.
Arnott, J A; Zhang, X; Sanjay, A; Owen, T A; Smock, S L; Rehman, S; DeLong, W G; Safadi, F F; Popoff, S N Bone 2008 May;42(5):871-85
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Novel role of protein kinase C-delta Tyr 311 phosphorylation in vascular smooth muscle cell hypertrophy by angiotensin II.
Nakashima, Hidekatsu; Frank, Gerald D; Shirai, Heigoro; Hinoki, Akinari; Higuchi, Sadaharu; Ohtsu, Haruhiko; Eguchi, Kunie; Sanjay, Archana; Reyland, Mary E; Dempsey, Peter J; Inagami, Tadashi; Eguchi, Satoru Hypertension 2008 Feb;51(2):232-8
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The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclasts.
Destaing, Olivier; Sanjay, Archana; Itzstein, Cecile; Horne, William C; Toomre, Derek; De Camilli, Pietro; Baron, Roland Molecular biology of the cell 2008 Jan;19(1):394-404
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Variant estrogen receptor-c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation.
Li, Lei; Hisamoto, Koji; Kim, Kyung Hee; Haynes, M Page; Bauer, Philip M; Sanjay, Archana; Collinge, Mark; Baron, Roland; Sessa, William C; Bender, Jeffrey R Proceedings of the National Academy of Sciences of the United States of America 2007 Oct;104(42):16468-73
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Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice.
Gil-Henn, Hava; Destaing, Olivier; Sims, Natalie A; Aoki, Kazuhiro; Alles, Neil; Neff, Lynn; Sanjay, Archana; Bruzzaniti, Angela; De Camilli, Pietro; Baron, Roland; Schlessinger, Joseph The Journal of cell biology 2007 Sep;178(6):1053-64
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Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl.
Sanjay, Archana; Miyazaki, Tsuyoshi; Itzstein, Cecile; Purev, Enkhtsetseg; Horne, William C; Baron, Roland The FEBS journal 2006 Dec;273(23):5442-56
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Cholesterol and steroid synthesizing smooth endoplasmic reticulum of adrenocortical cells contains high levels of proteins associated with the translocation channel.
Black, Virginia H; Sanjay, Archana; van Leyen, Klaus; Lauring, Brett; Kreibich, Gert Endocrinology 2005 Oct;146(10):4234-49
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Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity.
Bruzzaniti, Angela; Neff, Lynn; Sanjay, Archana; Horne, William C; De Camilli, Pietro; Baron, Roland Molecular biology of the cell 2005 Jul;16(7):3301-13
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Src kinase activity is essential for osteoclast function.
Miyazaki, Tsuyoshi; Sanjay, Archana; Neff, Lynn; Tanaka, Sakae; Horne, William C; Baron, Roland The Journal of biological chemistry 2004 Apr;279(17):17660-6
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Tyrosine phosphatase epsilon is a positive regulator of osteoclast function in vitro and in vivo.
Chiusaroli, Riccardo; Knobler, Hilla; Luxenburg, Chen; Sanjay, Archana; Granot-Attas, Shira; Tiran, Zohar; Miyazaki, Tsuyoshi; Harmelin, Alon; Baron, Roland; Elson, Ari Molecular biology of the cell 2004 Jan;15(1):234-44
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Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim.
Akiyama, Toru; Bouillet, Phillippe; Miyazaki, Tsuyoshi; Kadono, Yuho; Chikuda, Hirotaka; Chung, Ung-Il; Fukuda, Akira; Hikita, Atsuhiko; Seto, Hiroaki; Okada, Takashi; Inaba, Toshiya; Sanjay, Archana; Baron, Roland; Kawaguchi, Hiroshi; Oda, Hiromi; Nakamura, Kozo; Strasser, Andreas; Tanaka, Sakae The EMBO journal 2003 Dec;22(24):6653-64
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Deletion of the gene encoding c-Cbl alters the ability of osteoclasts to migrate, delaying resorption and ossification of cartilage during the development of long bones.
Chiusaroli, Riccardo; Sanjay, Archana; Henriksen, Kim; Engsig, Michael T; Horne, William C; Gu, Hua; Baron, Roland Developmental biology 2003 Sep;261(2):537-47
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Cholesterol and steroid synthesizing smooth endoplasmic reticulum of adrenocortical cells contains high levels of translocation apparatus proteins.
Black, V H; Sanjay, A; van Leyen, K; Möeller, I; Lauring, B; Kreibich, G Endocrine research 2002 Nov;28(4):425-30
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The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.
Sanjay, A; Horne, W C; Baron, R Science's STKE : signal transduction knowledge environment 2001 Nov;2001(110):pe40
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Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteins.
Yokouchi, M; Kondo, T; Sanjay, A; Houghton, A; Yoshimura, A; Komiya, S; Zhang, H; Baron, R The Journal of biological chemistry 2001 Sep;276(37):35185-93
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Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility.
Sanjay, A; Houghton, A; Neff, L; DiDomenico, E; Bardelay, C; Antoine, E; Levy, J; Gailit, J; Bowtell, D; Horne, W C; Baron, R The Journal of cell biology 2001 Jan;152(1):181-95
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Modification of the erythrocyte surface in rats bearing Yoshida ascites sarcoma is brought about by a tumour variant of alpha2-macroglobulin.
Sanjay, A; Kalraiya, R D; Mehta, N G The Biochemical journal 1997 Mar;322 ( Pt 2)379-84
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Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).
Wang, X Z; Lawson, B; Brewer, J W; Zinszner, H; Sanjay, A; Mi, L J; Boorstein, R; Kreibich, G; Hendershot, L M; Ron, D Molecular and cellular biology 1996 Aug;16(8):4273-80
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Isolation of a glycoprotein responsible for the enhanced concanavalin A agglutinability of erythrocytes in Yoshida-ascites-sarcoma-bearing rats: the mechanism of paraneoplastic syndromes.
Kalraiya, R D; Sanjay, A; Mehta, N G The Biochemical journal 1993 May;292 ( Pt 1)163-70