Photo of David A. Weinstein, M.D., M.Sc.

David A. Weinstein, M.D., M.Sc.

Professor of Medicine
Academic Office Location:
UConn Health
263 Farmington Avenue
Farmington, CT 06030
Phone: 860-837-7800
B.S.Trinity CollegeBiology
M.D.Harvard Medical SchoolMedicine
M.Sc.Massachusetts Institute of Technology/Harvard Medical SchoolClinical Investigation

Post-Graduate Training
InternshipChildren's Hospital BostonPediatrics
ResidencyChildren's Hospital BostonPediatrics (Chief Resident, 1997-1998)
FellowshipChildren's Hospital BostonEndrocrinology
Clinical InvestigatorMIT/HarvardClinical Investigator Training Program

Name of Award/HonorAwarding Organization
Named in "Best Doctors in America" 2007 - 2019
"Be My Sugar" Research AwardCongenital Hyperinsulinism International
Presidencia de Honor AwardGlucolatino, España
Clinical Research AwardUniversity of Florida College of Medicine
Lifetime Service AwardAssociation for Glycogen Storage Disease
Award for Dedication to the GSD Community (2014-2015)Glucolatino Columbia
Amigo de las Glucogenosis AwardAsociación Española de Enfermos de Glucogenosis
Inducted into Rare Disease Research Hall of Fame
Recipient of Order of the Smile Humanitarian Award (for Efforts to Help Children from Around the World)Order Usmiechu in Poland
Jan Albrecht AwardAmerican Association for the Study of Liver Diseases
Padrino de HonorFundacaion Glucolatino
George A. Sacher Award for Geriatric ResearchGerontological Society of America
Trinity College Alumni Award (Recognizing 5 Graduates for Excellence in Scholastic, Athletic, and Service Endeavors)Trinity College
Barry M. Goldwater Scholarship Recipient for the State of Florida (Congressional Award Granted Annually to One Student per State Who Demonstrates “Outstanding Potential in the Fields of Mathematics and the Natural Sciences”)
Holland ScholarTrinity College

Dr. Weinstein specializes in disorders of carbohydrate metabolism with particular focus on glycogen storage disease (GSD), hypoglycemia, and diabetes. As the director of the Glycogen Storage Disease Program, he manages the inpatient and outpatient care for the largest cohort of GSD patients in the world following over 500 people with this disorder. Of these, over 225 patients have glycogen storage disease type Ia, 70 patients have glycogen storage disease type Ib, 50 patients have type III glycogen storage disease, and over 200 patients with types 0, VI, or IX GSD. His patients come from over 49 states and 43 countries to be cared for by him. Dr. Weinstein attends for the majority of glycogen storage disease inpatient evaluations along with 1-2 months per year on the inpatient endocrinology service.

Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
Scientific Organizing Committee, 2019 International GSD Conference, Porto Alegre, Brazil.Education CommitteeExternalInternational20182019
James Link Alliance Priority Setting Partnership Steering Committee (United Kingdom)Professional/Scientific OrganizationExternalInternational20172019
NICHD Pediatrics (CHHD-A) Review Committee (Permanent Member)Study SectionExternalNational2016
Clinical Advisory Committee, DTX401 Trial, Ultragenyx TherapeuticsResearch CommitteeChairmanExternalInternational2015
Scientific Advisory Committee, Dimension Therapeutics / Ultragenyx TherapeuticsAdvisory CommitteeExternalInternational2015
DSMB Member, New Drug Trial, PfizerAdvisory CommitteeMemberExternalNational20052009
Association for Glycogen Storage DiseaseAdvisory CommitteeBoard of DirectorsExternalNational20022007
Association for Glycogen Storage Disease (United Kingdom)Professional/Scientific OrganizationExternalInternational2002
Association for Glycogen Storage Disease (United States)Professional/Scientific OrganizationExternalNational1999
GLYDE Trial Steering Committee, Vitaflo CorporationResearch CommitteeVice ChairExternalInternational
Rare Disease Task Force for the State of ConnecticutAdvisory CommitteeExternalState
Scandinavian Association for Glycogen Storage DiseaseProfessional/Scientific OrganizationExternalInternational

Understanding the pathophysiology of hypoglycemia in children with a focus on the causes of ketotic hypoglycemia.

Investigation into the cause of morbidity type 0 and I glycogen storage disease including the pathophysiology of hepatic adenomas, hepatocellular carcinoma, nephrolithiasis, anemia, and focal segmental glomerulosclerosis.

Attempted methods of repairing the enzymatic defect in the glycogen storage diseases.

Journal Articles


  • Response letter.
    Lee, Youngmok; Chou, Janice Y; Weinstein, David A Journal of inherited metabolic disease 2018 Sep;41915


Title or AbstractTypeSponsor/EventDate/YearLocation
Gene Therapy for Glycogen Storage Disease: Delivering on a PromiseLectureGlucolatino Ecuador2019Quito, Ecuador
Research Update: Gene Therapy and Other Progress since 2015LectureFuglucol and Glucolatino2019Cali, Colombia
DTX 401 Phase I/II Gene Therapy Study: Lessons Learned.LectureUltragenyx European Investigator Meeting2018Madrid, Spain
Gene therapy for glycogen storage disease type IaLectureAssociation for Glycogen Storage Disease (UK)2018Wyboston Lakes, United Kingdom
Research update for types III, IV, VI, and IX glycogen storage disease.LectureIX Congreso Iberoamericano de Glucogenosis.2018Fuengirola, Spain
Gene therapy for glycogen storage disease type Ia.LectureIX Congreso Iberoamericano de Glucogenosis.2018Fuengirola, Spain
Forty Years of Progress: Reflections on Returning to IowaLectureAssociation for Glycogen Storage Disease Annual Conference2018Davenport, IA
Glycogen storage disease type I: From glycogen to gene therapy (and everything in-between),LectureGenetic Metabolic Dietitians International2018Orlando, FL
Hepatic glycogen storage: Prevention of Complications and Future Therapies.LectureScandinavian Association for Glycogen Storage Disease.2018Angelholm, Sweden
Research Update: Gene Therapy and MoreLectureAsociación SHG Glycogenose.2018Duderstadt, Germany
Born This Way, Hepatic Glycogen Storage Disease UpdateLectureVIA Symposium2018Berlin, Germany
Reflections on Returning to Trinity: Lessons from a Rare Disease.LectureTrinity College / Health Sciences Student Seminar Series2018Hartford, CT