Education

Degree	Institution	Major
BS	University of Connecticut	Biophysics
MS	University of Connecticut	Chemistry
PhD	Stanford University	Biophysics

Post-Graduate Training

Training	Institution	Specialty
Postdoctoral	European Molecular Biology Laboratory	Postdoctoral Research Assistant in the Laboratory of Dr. Hartmut Oschkinat.
Postdoctoral	University of Connecticut Health Center	Postdoctoral Research Assistant in the Laboratory of Dr. Gregory P. Mullen

Awards

Name of Award/Honor	Awarding Organization
DAAD post-doctoral fellowship (declined)	Deutscher Akademischer Austausch Dienst
Who's Who Among Students in American Universities	Who's Who Among Students in American Universities
Training Grant 1990-1994	NIH
Who's Who Among Students in American Universities	Who's Who Among Students in American Universities
Member	Golden Key National Honor Society
Biophysics Award for Distinguished Undergraduate Research Honors Scholar	Phi Beta Kappa Honor Society
Who's Who Among Students in American Universities	Who's Who Among Students in American Universities
University Scholar	UCONN Phi Kappa Phi Honor Society
Member	Alpha Lambda Delta Honor Society
Bruce Mahon Scholarship 1986-1990

Name & Description	Category	Role	Type	Scope	Start Year	End Year
IT Liaison	Advisory Committee	Member	UConn Health	University	2012

The focus of our laboratory is structural bioinformatics. We are currently involved in several projects on this topic, mainly the use of NMR spectroscopy as a tool for macromolecular characterization and molecular structure as an aid to bioinformatics.

Particular projects include the development of CONNJUR (connjur.uchc.edu) – an open source integration platform for biomolecular NMR data processing; utilizing non-uniform sampling techniques and the use of maximum entropy methods for spectral reconstruction; and the development of a database of short linear motifs which confer specific functions to proteins (mnm.engr.uconn.edu). NMR studies involve DNA repair proteins of relatively large molecular weight for NMR spectroscopy (20-70 kDa). Current methods to overcome the difficulties inherent in studying these large systems include extensive labeling using stable isotopes and the use of TROSY-based pulse sequences. A critical mission of the lab is the facility approach to NMR, such that as advancements are made, they are tailored for ease-of-use both internally and externally when possible.

--CONNJUR NMR Software Integration
--MiniMotif Miner
--Structural Biology Facility
--Structural Biology Tools

Accepting Lab Rotation Students: Fall 2022 and Spring 2023

Journal Articles

Books

Conference Papers

Letters

Notes

Other

Reviews

Title or Abstract	Type	Sponsor/Event	Date/Year	Location
Data, Meet Computation	Poster	Experimental NMR Conference	2022	Orlando, FL
Storied Past, Bright Future: A Provenance Jam Session.	Panel Discussion	Association for Information Science and Technology	2022	Pittsburgh, PA
Curating Scientific Workflows for Biomolecular Nuclear Magnetic Resonance Spectroscopy.	Talk	International Digital Curation Conference	2018	Barcelona, Spain
Semantic Mediation to Improve Reproducibility for Biomolecular NMR Analysis.	Talk	iConference 2018	2018	Sheffield, UK