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Intermittent clearance of p21-highly-expressing cells extends lifespan and confers sustained benefits to health and physical function.
Wang, Binsheng; Wang, Lichao; Gasek, Nathan S; Kuo, Chia-Ling; Nie, Jia; Kim, Taewan; Yan, Pengyi; Zhu, Junyu; Torrance, Blake L; Zhou, Yueying; Flores, Lisa C; Allen, Colton; Andrade, Allison M; Guo, Chun; Cohn, Rachel L; Jellison, Evan R; Bartley, Jenna M; Kuchel, George A; Li, Sheng; Pirtskhalava, Tamar; Tchkonia, Tamar; Yadav, Sumit; Haynes, Laura; Kirkland, James L; Ikeno, Yuji; Xu, Ming Cell Metabolism. 2024 Aug;36(8):1795-1805.e6
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Cellular senescence is a double-edged sword in regulating aged immune responses to influenza.
Torrance, Blake L; Cadar, Andreia N; Panier, Hunter A; Martin, Dominique E; Lorenzo, Erica C; Jellison, Evan R; Bartley, Jenna M; Haynes, Laura Aging cell 2024 Apr;e14162
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Unleashing CAR T cells to delay metabolic aging.
Bartley, Jenna M; Xu, Ming Nature aging 2024 Feb;
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Patient-derived organoids recapitulate glioma-intrinsic immune program and progenitor populations of glioblastoma.
Watanabe, Fumihiro; Hollingsworth, Ethan W; Bartley, Jenna M; Wisehart, Lauren; Desai, Rahil; Hartlaub, Annalisa M; Hester, Mark E; Schiapparelli, Paula; Quiñones-Hinojosa, Alfredo; Imitola, Jaime PNAS nexus 2024 Feb;3(2):pgae051
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Unraveling the association between major depressive disorder and senescent biomarkers in immune cells of older adults: a single-cell phenotypic analysis.
Lorenzo, Erica C; Figueroa, Jovany E; Demirci, Derya A; El-Tayyeb, Ferris; Huggins, Billy J; Illindala, Medha; Bartley, Jenna M; Haynes, Laura; Diniz, Breno S Frontiers in aging 2024 Jan;51376086
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Dysfunctional Bladder Morphology and Functional Impairments Are Identified in the Alzheimer's Disease APPNL-G-F/NL-G-F Murine Model.
Ge, Yingying; AlObaidi, Alya S; Kuchel, George A; Bartley, Jenna M; Smith, Phillip P; He, Wanxia; Hu, Xiangyou Journal of Alzheimer's Disease : JAD. 2023 Dec;
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Metformin for Treatment of Acute COVID-19: Systematic Review of Clinical Trial Data Against SARS-CoV-2.
Erickson, Spencer M; Fenno, Sarah L; Barzilai, Nir; Kuchel, George; Bartley, Jenna M; Justice, Jamie Nicole; Buse, John B; Bramante, Carolyn T Diabetes Care. 2023 Jul;46(7):1432-1442
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Nanofiber matrix formulations for the delivery of Exendin-4 for tendon regeneration: In vitro and in vivo assessment.
Abdulmalik, Sama; Gallo, Jack; Nip, Jonathan; Katebifar, Sara; Arul, Michael; Lebaschi, Amir; Munch, Lucas N; Bartley, Jenna M; Choudhary, Shilpa; Kalajzic, Ivo; Banasavadi-Siddegowdae, Yeshavanth Kumar; Nukavarapu, Syam P; Kumbar, Sangamesh G Bioactive materials 2023 Jul;2542-60
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A pilot metabolomic study of drug interaction with the immune response to seasonal influenza vaccination.
Siddiqa, Amnah; Wang, Yating; Thapa, Maheshwor; Martin, Dominique E; Cadar, Andreia N; Bartley, Jenna M; Li, Shuzhao NPJ vaccines 2023 Jun;8(1):92
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The effect of metformin on influenza vaccine responses in nondiabetic older adults: a pilot trial.
Martin, Dominique E; Cadar, Andreia N; Panier, Hunter; Torrance, Blake L; Kuchel, George A; Bartley, Jenna M. Immunity & Ageing. 2023 May;20(1):18
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Loss of resilience contributes to detrusor underactivity in advanced age.
Ramasamy, Ramalakshmi; Baker, Dylan S; Lemtiri-Chlieh, Fouad; Rosenberg, Dawn A; Woon, Eric; Al-Naggar, Iman M; Hardy, Cara C; Levine, Eric S; Kuchel, George A; Bartley, Jenna M; Smith, Phillip P Biogerontology 2023 Jan;
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Senolytic treatment with dasatinib and quercetin does not improve overall influenza responses in aged mice.
Torrance, Blake L; Cadar, Andreia N; Martin, Dominique E; Panier, Hunter A; Lorenzo, Erica C; Bartley, Jenna M; Xu, Ming; Haynes, Laura Frontiers in aging 2023 Jan;41212750
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Altered T cell infiltration and enrichment of leukocyte regulating pathways within aged skeletal muscle are associated impaired muscle function following influenza infection.
Keilich, Spencer R; Cadar, Andreia N; Ahern, Darcy T; Torrance, Blake L; Lorenzo, Erica C; Martin, Dominique E; Haynes, Laura; Bartley, Jenna M GeroScience 2022 Dec;
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Loss of resilience contributes to detrusor underactivity in advanced age.
Ramasamy R, Baker DS, Lemitiri-Chlieh F, Rosenberg DA, Woon E, Al-Naggar IM, Hardy CC, Levine ES, Kuchel GA, Bartley JM, Smith PP Biogerontology 2022 Dec;
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Senescence-induced changes in CD4 T cell differentiation can be alleviated by treatment with senolytics.
Lorenzo, Erica C; Torrance, Blake L; Keilich, Spencer R; Al-Naggar, Iman; Harrison, Andrew; Xu, Ming; Bartley, Jenna M; Haynes, Laura Aging cell 2022 Jan;e13525
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Biopolymer-nanotube nerve guidance conduit drug delivery for peripheral nerve regeneration: In vivo structural and functional assessment.
Manoukian, Ohan S; Rudraiah, Swetha; Arul, Michael R; Bartley, Jenna M; Baker, Jiana T; Yu, Xiaojun; Kumbar, Sangamesh G Bioactive materials 2021 Sep;6(9):2881-2893
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Increased Levels of Circulating Cell-Free mtDNA in the Plasma of Subjects With Late-Life Depression and Frailty: A Preliminary Study.
Ampo, Emi; Mendes-Silva, Ana Paula; Goncalves, Vanessa; Bartley, Jenna M; Kuchel, George A; Diniz, Breno S The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2021 Jul;
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Network Topology of Biological Aging and Geroscience-Guided Approaches to COVID-19
Landay A, Bartley JM, Banerjee D, Hargis G, Haynes L, Keshavarzian A, Kuo C-L, Kwon OS, Li S, Li S, Oh J, Ozbolat IT, Ucar D, Xu M, Yao X, Unutmaz D and Kuchel GA Frontiers in Aging 2021 Jul;
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Targeting Aging: Lessons Learned From Immunometabolism and Cellular Senescence.
Martin DE, Torrance BL, Haynes L, Bartley JM. Frontiers in Immunology 2021 Jul;12
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Better, Faster, Stronger: mRNA Vaccines Show Promise for Influenza Vaccination in Older Adults.
Bartley, Jenna M; Cadar, Andreia N; Martin, Dominique E Immunological investigations 2021 Apr;1-11
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A multi-center trial of exercise and testosterone therapy in women after hip fracture: Design, methods and impact of the COVID-19 pandemic.
Binder, Ellen F; Christensen, Jesse C; Stevens-Lapsley, Jennifer; Bartley, Jenna; Berry, Sarah D; Dobs, Adrian S; Fortinsky, Richard H; Hildreth, Kerry L; Kiel, Douglas P; Kuchel, George A; Marcus, Robin L; McDonough, Christine M; Orwig, Denise; Sinacore, David R; Schwartz, Robert S; Volpe, Elena; Magaziner, Jay; Schechtman, Kenneth B Contemporary clinical trials 2021 Mar;106356
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Effects of cold water immersion on circulating inflammatory markers at the Kona Ironman World Championship.
Bartley, Jenna M; Stearns, Rebecca L; Munoz, Colleen; Nolan, Julie K; Radom-Aizik, Shlomit; Maresh, Carl M; Casa, Douglas J; Zaldivar, Frank P; Haddad, Fadia; Ganio, Matthew S; Lee, Elaine Choung-Hee Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2021 Jan;
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A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin.
Justice, Jamie N; Gubbi, Sriram; Kulkarni, Ameya S; Bartley, Jenna M; Kuchel, George A; Barzilai, Nir GeroScience 2020 Sep;
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Influenza infection has fiber type-specific effects on cellular and molecular skeletal muscle function in aged mice.
Straight, Chad R; Ringham, Olivia R; Bartley, Jenna M; Keilich, Spencer R; Kuchel, George A; Haynes, Laura; Miller, Mark S The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Jun;
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Vaccination mitigates influenza-induced muscular declines in aged mice.
Keilich, Spencer R; Lorenzo, Erica C; Torrance, Blake L; Harrison, Andrew G; Bartley, Jenna M; Haynes, Laura GeroScience 2020 May;
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Diminished immune responses with aging predispose older adults to common and uncommon influenza complications.
Keilich, Spencer R; Bartley, Jenna M; Haynes, Laura Cellular immunology 2019 Oct;103992
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Assessment of lymph node stromal cells as an underlying factor in age-related immune impairment.
Masters, April R; Hall, Alexxus; Bartley, Jenna M; Keilich, Spencer R; Lorenzo, Erica C; Jellison, Evan R; Puddington, Lynn; Haynes, Laura The journals of gerontology. Series A, Biological sciences and medical sciences 2019 Feb;
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Muscle Ultrasound As a Link to Muscle Quality and Frailty in the Clinic.
Bartley, Jenna M; Studenski, Stephanie A Journal of the American Geriatrics Society 2017 Dec;65(12):2562-2563
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Report: NIA Workshop on Measures of Physiologic Resiliencies in Human Aging.
Hadley EC, Kuchel GA, Newman AB, Allore HG, Bartley JM, Bergeman CS, Blinov ML, Colon-Emeric CS, Dhabhar FS, Dugan LL, Dutta C, Eldadah BA, Ferrucci L, Kirkland JL, Kritchevsky SB, Lipsitz LA, Nadkarni NK, Reed MJ, Schmader KE, Sierra F, Studenski SA, Varadhan R, Walston JD, Whitson HE, Yung R The journals of gerontology. Series A, Biological sciences and medical sciences 2017 May;72980-990
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Impact of Age, Caloric Restriction, and Influenza Infection on Mouse Gut Microbiome: An Exploratory Study of the Role of Age-Related Microbiome Changes on Influenza Responses.
Bartley, Jenna M; Zhou, Xin; Kuchel, George A; Weinstock, George M; Haynes, Laura Frontiers in immunology 2017 Jan;81164
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Metabolic characteristics of keto-adapted ultra-endurance runners.
Volek, Jeff S; Freidenreich, Daniel J; Saenz, Catherine; Kunces, Laura J; Creighton, Brent C; Bartley, Jenna M; Davitt, Patrick M; Munoz, Colleen X; Anderson, Jeffrey M; Maresh, Carl M; Lee, Elaine C; Schuenke, Mark D; Aerni, Giselle; Kraemer, William J; Phinney, Stephen D Metabolism: clinical and experimental 2016 Mar;65(3):100-10
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Aging augments the impact of influenza respiratory tract infection on mobility impairments, muscle-localized inflammation, and muscle atrophy.
Bartley, Jenna M; Pan, Sarah J; Keilich, Spencer R; Hopkins, Jacob W; Al-Naggar, Iman M; Kuche, George A; Haynes, Laura Aging 2016 Feb;8620-35
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Effects of fatigue from resistance training on barbell back squat biomechanics.
Hooper, David R; Szivak, Tunde K; Comstock, Brett A; Dunn-Lewis, Courtenay; Apicella, Jenna M; Kelly, Neil A; Creighton, Brent C; Flanagan, Shawn D; Looney, David P; Volek, Jeff S; Maresh, Carl M; Kraemer, William J Journal of strength and conditioning research 2014 Apr;28(4):1127-34
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Repetitive box lifting performance is impaired in a hot environment: implications for altered work-rest cycles.
Maresh, Carl M; Sökmen, Bulent; Armstrong, Lawrence E; Dias, Joao C; Pryor, J Luke; Creighton, Brent C; Muñoz, Colleen X; Apicella, Jenna M; Casa, Douglas J; Lee, Elaine C; Anderson, Jeffery M; Kraemer, William J Journal of occupational and environmental hygiene 2014 Jan;11(7):460-8
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Adrenal cortical responses to high-intensity, short rest, resistance exercise in men and women.
Szivak, Tunde K; Hooper, David R; Dunn-Lewis, Courtenay; Comstock, Brett A; Kupchak, Brian R; Apicella, Jenna M; Saenz, Catherine; Maresh, Carl M; Denegar, Craig R; Kraemer, William J Journal of strength and conditioning research 2013 Mar;27(3):748-60
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Betaine supplementation enhances anabolic endocrine and Akt signaling in response to acute bouts of exercise.
Apicella, Jenna M; Lee, Elaine C; Bailey, Brooke L; Saenz, Catherine; Anderson, Jeffrey M; Craig, Stuart A S; Kraemer, William J; Volek, Jeff S; Maresh, Carl M European journal of applied physiology 2013 Mar;113(3):793-802
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Effects of resistance training fatigue on joint biomechanics.
Hooper, David R; Szivak, Tunde K; Distefano, Lindsay J; Comstock, Brett A; Dunn-Lewis, Courtenay; Apicella, Jenna M; Kelly, Neil A; Creighton, Brent C; Volek, Jeff S; Maresh, Carl M; Kraemer, William J Journal of strength and conditioning research 2013 Jan;27(1):146-53
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Eleven days of moderate exercise and heat exposure induces acclimation without significant HSP70 and apoptosis responses of lymphocytes in college-aged males.
Hom, Lindsay L; Lee, Elaine Choung-Hee; Apicella, Jenna M; Wallace, Sean D; Emmanuel, Holly; Klau, Jennifer F; Poh, Paula Y S; Marzano, Stefania; Armstrong, Lawrence E; Casa, Douglas J; Maresh, Carl M Cell stress & chaperones 2012 Jan;17(1):29-39
