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Lance Bauer, PhDProfessor of Psychiatry
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- Overview
- Education & Training
- Teaching
- Committees & Organizations
- Research
- Research Opportunities
- Lab Rotations
- Publications
Dr. Lance Bauer is a Professor in the Department of Psychiatry and PI of the NIAAA-funded Alcohol Research Center. He is co-PI of a T32-funded Institutional Training Program in Alcohol Research for postdoctoral fellows. Dr. Bauer plays a vital role in the activities of the Department of Psychiatry and UConn Health by serving on the ARC's Executive Committee, Scientific Advisory Committees for the CRC and IRB, and the Senior Appointments and Promotions Committee for the School of Medicine. His research program focuses on cognitive dysfunction and its contribution to psychopathology.
Dr. Bauer is also involved in research at the national level. He is a member of the Research Society on Alcoholism and the College on Problems of Drug Dependence. In addition, he is frequently called upon to review grant proposals for the NIH.
Education
Post-Graduate Training
| Degree | Institution | Major |
|---|---|---|
| BA | University of Rochester | Psychology |
| PhD | Washington University | Psychology |
Post-Graduate Training
| Training | Institution | Specialty |
|---|---|---|
| Fellowship | University of Oklahoma Health Sciences Center | Neurophysiology |
| Fellowship | University of Connecticut School of Medicine | Alcohol Research Center Department of Psychiatry |
Training of postdoctoral fellows
| Name & Description | Category | Role | Type | Scope | Start Year | End Year |
|---|---|---|---|---|---|---|
| Alcohol Research Center/BioScience CT faculty search committee | Other | Chair | UConn Health | Local | 2021 | 2021 |
| UConn Health IRB Scientific Advisory Committee | Advisory Committee | Member | UConn Health | Local | 2019 | |
| CSR Population and Public Health Approaches to HIV (PPAH) Most recent meetings: 7/12/21 | Study Section | Temporary member | External | National | 2016 | 2021 |
| School of Medicine Senior Appointments and Promotions Committee | Advisory Committee | Reviewer | UConn Health | University | 2010 | 2022 |
| Chair/Co-Chair, Dept of Psychiatry Grand Rounds | Education Committee | Co-Chair | UConn Health | University | 2010 | |
| CSR Adult Psychopathology and Disorders of Aging Most recent meetings: 6/3/2019 and 10/22/2018 | Study Section | Temporary Member | External | National | 2008 | 2019 |
| CSR NeuroAIDS and Other End Organ Diseases (NAED) Most recent meeting 7/18/2018 | Study Section | Regular member | External | National | 2008 | 2017 |
| ZAA1GG(32) NIAAA F31/F32 Review Group Most recent meetings: 7/7/2021 | Study Section | Chair | External | National | 2008 | 2021 |
| Clinical Research Center Scientific Advisory Committee | Advisory Committee | Standing member | UConn Health | Local | 2000 | 2019 |
| Alcohol Research Center Executive Committee | Research Committee | Chair | UConn Health | Local | 1988 | 2024 |
| ZDA1SKM-D (04), NIH pathways to independence study section, meeting date 3/1/2021 | Study Section | Chair | External | National | ||
| NIAAA/NIH, Loan Repayment Program Review Committee | Study Section | Study section reviewer | External | National |
Genetic and personality risk factors for addiction and their neurophysiological correlates.
Students with expertise in neurobiology or computer science can use our neuroimaging software to conduct secondary analyses of EEG/ERP data for class projects or publications.
Not accepting students for Lab Rotations at this time
Journal Articles
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Intraindividual variability in brain activation-A novel correlate of obesity risk among female college students.
Brain and cognition 2023 Jun;168105985
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Examining associations between genetic and neural risk for externalizing behaviors in adolescence and early adulthood.
Psychological medicine 2023 May;1-11
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Altered brain activation in uncomplicated pediatric obesity: The second moment is more sensitive than the first.
Brain and cognition 2022 Dec;164105923
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Signal in the noise: Altered brain activation among adolescent alcohol users detected via the analysis of intra-individual variability1.
Psychopharmacology 2022 Nov;239(11):3595-3604
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Inter-trial variability in postural control and brain activation: Effects of previous opiate abuse.
Biological psychology 2022 Oct;174108424
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Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk.
Translational psychiatry 2022 Sep;12(1):420
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Evaluating risk for alcohol use disorder: Polygenic risk scores and family history.
Alcoholism, clinical and experimental research 2022 Mar;46(3):374-383
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Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.
Nature neuroscience 2021 Oct;24(10):1367-1376
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Temporal instability in brain activation: a novel paradigm for evaluating the maintenance of attention among substance dependent patients.
Psychopharmacology 2021 Jul;
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Predicting alcohol use disorder remission: a longitudinal multimodal multi-featured machine learning approach.
Translational psychiatry 2021 Mar;11(1):166
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Pathways to post-traumatic stress disorder and alcohol dependence: Trauma, executive functioning, and family history of alcoholism in adolescents and young adults.
Brain and behavior 2020 Sep;e01789
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Neural Responses to Signals for Behavior Change: Greater Within-Person Variability is Associated With Risk Factors for Substance Dependence.
Alcoholism, clinical and experimental research 2020 Jul;
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GRM8 genotype is associated with externalizing disorders and greater inter-trial variability in brain activation during a response inhibition task.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2020 Jun;131(6):1180-1186
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A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior.
Molecular psychiatry 2020 May;265040-5052
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GRM8 genotype is associated with substance dependence and unstable brain activation during a response inhibition task
Clinical Neurophysiology 2020 Apr;1311180-1186
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Density and Dichotomous Family History Measures of Alcohol Use Disorder as Predictors of Behavioral and Neural Phenotypes: A Comparative Study Across Gender and Race/Ethnicity.
Alcoholism, clinical and experimental research 2020 Jan;
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ERRATUM: Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans.
Genes, brain, and behavior 2019 Nov;18(8):e12608
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Predicting risk for Alcohol Use Disorder using longitudinal data with multimodal biomarkers and family history: a machine learning study.
Molecular psychiatry 2019 Oct;
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Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans.
Genes, brain, and behavior 2019 May;e12580
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Multivariate Analyses Reveal Biological Components Related to Neuronal Signaling and Immunity Mediating Electroencephalograms Abnormalities in Alcohol-Dependent Individuals from the Collaborative Study on the Genetics of Alcoholism Cohort.
Alcoholism, clinical and experimental research 2019 Apr;
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Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism.
Translational psychiatry 2019 Feb;9(1):89
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Early Sexual Trauma Exposure and Neural Response Inhibition in Adolescence and Young Adults: Trajectories of Frontal Theta Oscillations During a Go/No-Go Task.
Journal of the American Academy of Child and Adolescent Psychiatry 2019 Feb;58(2):242-255.e2
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Inter-trial variability in brain activity as an indicator of synergistic effects of HIV-1 and drug abuse.
Drug and alcohol dependence 2018 Aug;191300-308
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HIV/AIDS and an overweight body mass are associated with excessive intra-individual variability in response preparation.
Journal of neurovirology 2018 May;24577-586
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Variation in SWI/SNF Chromatin Remodeling Complex Proteins is Associated with Alcohol Dependence and Antisocial Behavior in Human Populations.
Alcoholism, clinical and experimental research 2017 Dec;41(12):2033-2040
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The value of instability: An investigation of intra-subject variability in brain activity among obese adolescent girls.
International journal of obesity (2005) 2017 Jun;411489-1495
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A genome wide association study of fast beta EEG in families of European ancestry.
International journal of psychophysiology : official journal of the International Organization of Psychophysiology 2017 May;11574-85
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Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms.
Alcoholism, clinical and experimental research 2017 May;41(5):911-928
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An endophenotype approach to the genetics of alcohol dependence: a genome wide association study of fast beta EEG in families of African ancestry.
Molecular psychiatry 2017 Jan;221767-1775
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The Impact of Peer Substance Use and Polygenic Risk on Trajectories of Heavy Episodic Drinking Across Adolescence and Emerging Adulthood.
Alcoholism, clinical and experimental research 2016 Dec;4165-75
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Challenges in the Detection of Working Memory and Attention Decrements among Overweight Adolescent Girls.
Neuropsychobiology 2016 Jan;73(1):43-51
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Reward processing deficits and impulsivity in high-risk offspring of alcoholics: A study of event-related potentials during a monetary gambling task.
International journal of psychophysiology : official journal of the International Organization of Psychophysiology 2015 Sep;98(2 Pt 1):182-200
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Visual illusions and inattention: Their association with adiposity among adolescent girls.
Appetite 2015 Jul;95310-6
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Deficient Event-Related Theta Oscillations in Individuals at Risk for Alcoholism: A Study of Reward Processing and Impulsivity Features.
PloS one 2015 Jan;10(11):e0142659
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Who gains? Genetic and neurophysiological correlates of BMI gain upon college entry in women.
Appetite 2014 Jul;82160-5
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Neural and genetic correlates of binge drinking among college women.
Biological psychology 2014 Feb;97(10):43-8
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A family history of substance dependence obscures the group differences in brain function associated with HIV-1 and ART.
Drug and alcohol dependence 2013 Jan;127(1-3):45-52
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GABRA2 and KIBRA genotypes predict early relapse to substance use.
Drug and alcohol dependence 2012 Jun;123(1-3):154-9
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Attention deficit hyperactivity symptoms and risky sexual behavior in young adult women.
Journal of women's health (2002) 2012 Apr;21(4):463-8
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GABRA2 genotype, impulsivity, and body mass.
The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions 2012 Jan;21(5):404-10
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An obese body mass increases the adverse effects of HIV/AIDS on balance and gait.
Physical therapy 2011 Jul;91(7):1063-71
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Interactive effects of HIV/AIDS, body mass, and substance abuse on the frontal brain: a P300 study.
Psychiatry research 2011 Jan;185(1-2):232-7
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P300 and the stroop effect in overweight minority adolescents.
Neuropsychobiology 2010 Jan;61(4):180-7
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Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009 Apr;150B(3):359-68
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Psychiatric and neurophysiological predictors of obesity in HIV/AIDS.
Psychophysiology 2008 Nov;45(6):1055-63
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A family history of psychopathology modifies the decrement in cognitive control among patients with HIV/AIDS.
Brain and cognition 2008 Jun;67(1):103-14
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The effects of HIV on P300 are moderated by familial risk for substance dependence: implications for a theory of brain reserve.
Drug and alcohol dependence 2008 Apr;94(1-3):92-100
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Genetic influences on bipolar EEG power spectra.
International journal of psychophysiology : official journal of the International Organization of Psychophysiology 2007 Jul;65(1):2-9
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A cholinergic receptor gene (CHRM2) affects event-related oscillations.
Behavior genetics 2006 Sep;36(5):627-39
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ASPD blunts the effects of HIV and antiretroviral treatment on event-related brain potentials.
Neuropsychobiology 2006 Jan;53(1):17-25
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Brain maturation in conduct disorder versus borderline personality disorder.
Neuropsychobiology 2006 Jan;53(2):94-100
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Borderline personality disorder features in adolescent girls: P300 evidence of altered brain maturation.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2005 Jun;116(6):1424-32
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Sensorimotor dysfunction in HIV/AIDS: effects of antiretroviral treatment and comorbid psychiatric disorders.
AIDS (London, England) 2005 Mar;19(5):495-502
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Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition.
International journal of psychophysiology : official journal of the International Organization of Psychophysiology 2004 Jul;53(2):75-90
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Effects of borderline personality disorder features and a family history of alcohol or drug dependence on P300 in adolescents.
International journal of psychophysiology : official journal of the International Organization of Psychophysiology 2004 Jun;53(1):57-70
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P300 evidence of cognitive inflexibility in female adolescents at risk for recurrent depression.
Progress in neuro-psychopharmacology & biological psychiatry 2004 May;28(3):529-36
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Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations.
American journal of human genetics 2004 Apr;74(4):705-14
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Depression and familial risk for substance dependence: a P300 study of young women.
Psychiatry research 2003 Sep;124(1):49-62
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Brain maturation and subtypes of conduct disorder: interactive effects on p300 amplitude and topography in male adolescents.
Journal of the American Academy of Child and Adolescent Psychiatry 2003 Jan;42(1):106-15
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Lateral asymmetries in the frontal brain: effects of depression and a family history of alcoholism in female adolescents.
Alcoholism, clinical and experimental research 2002 Nov;26(11):1662-8
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Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus.
Proceedings of the National Academy of Sciences of the United States of America 2002 Mar;99(6):3729-33
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Relationship of cognitive ability to the developmental course of antisocial behavior in substance-dependent patients.
Progress in neuro-psychopharmacology & biological psychiatry 2001 Nov;25(8):1523-36
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CSD/BEM localization of P300 sources in adolescents "at-risk": evidence of frontal cortex dysfunction in conduct disorder.
Biological psychiatry 2001 Oct;50(8):600-8
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Effects of alcoholism, anxiety and depression on P300 in women: a pilot study.
Journal of studies on alcohol 2001 Sep;62(5):571-9
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Predicting relapse to alcohol and drug abuse via quantitative electroencephalography.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001 Sep;25(3):332-40
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P300 event-related potential amplitude as an endophenotype of alcoholism--evidence from the collaborative study on the genetics of alcoholism.
Journal of biomedical science 2001 Jan;8(1):77-82
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Frontal P300 decrements, alcohol dependence, and antisocial personality disorder.
Biological psychiatry 2000 Jun;47(12):1064-71
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Responses to rare visual target and distractor stimuli using event-related fMRI.
Journal of neurophysiology 2000 May;83(5):3133-9
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Heritability of event-related brain potentials in families with a history of alcoholism.
American journal of medical genetics 1999 Aug;88(4):383-90
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P300 decrements in teenagers with conduct problems: implications for substance abuse risk and brain development.
Biological psychiatry 1999 Jul;46(2):263-72
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Neuropsychologic findings in cocaine-dependent outpatients.
Progress in neuro-psychopharmacology & biological psychiatry 1998 Oct;22(7):1061-76
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Quantitative trait loci analysis of human event-related brain potentials: P3 voltage.
Electroencephalography and clinical neurophysiology 1998 Apr;108(3):244-50
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Effects of naltrexone on cue-elicited craving for alcohol and cocaine.
Drug and alcohol dependence 1997 Dec;49(1):9-16
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Chronic alcohol abuse and the acute sedative and neurophysiologic effects of midazolam.
Psychopharmacology 1997 Oct;133(3):293-9
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Antisocial personality disorder, childhood delinquency, and frontal brain functioning: EEG and neuropsychological findings.
Journal of clinical psychology 1996 Nov;52(6):639-50
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Anterior brain dysfunctioning as a risk factor in alcoholic behaviors.
Addiction (Abingdon, England) 1995 Oct;90(10):1323-34
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Relationship between alcohol-related expectancies and anterior brain functioning in young men at risk for developing alcoholism.
Alcoholism, clinical and experimental research 1995 Apr;19(2):476-81
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Frontal P300 decrements in antisocial personality disorder.
Alcoholism, clinical and experimental research 1994 Dec;18(6):1300-5
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Reduced P3 amplitudes are associated with both a family history of alcoholism and antisocial personality disorder.
Progress in neuro-psychopharmacology & biological psychiatry 1994 Dec;18(8):1307-21
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P300 differences between non-alcoholic young men at average and above-average risk for alcoholism: effects of distraction and task modality.
Progress in neuro-psychopharmacology & biological psychiatry 1994 Mar;18(2):263-77
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EEG, autonomic and subjective correlates of the risk for alcoholism.
Journal of studies on alcohol 1993 Sep;54(5):577-89
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Reduced P300 amplitude in relation to family history of alcoholism and antisocial personality disorder among young men at risk for alcoholism.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement 1993 Jan;295-100
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Variation in evoked potential measures over the menstrual cycle: a pilot study.
Progress in neuro-psychopharmacology & biological psychiatry 1992 Jan;16(6):901-11
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GRM8 genotype is associated with substance dependence and unstable brain activation during a response inhibition task
Clinical Neurophysiology
Book Chapters
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Chapter 4: Electroencephalographic Studies of Substance Use and Abuse
Brain Imaging in Substance Abuse: Research, Clinical, and Forensic Applications 77-112
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Neurophysiological and Cognitive Correlates of Antisocial Behavior
The Science, Treatment, and Prevention of Antisocial Behaviors 5.2-5.23
Reviews
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Neuropsychological factors in individuals at high risk for alcoholism.
Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism 1991 Jan;921-40