Faculty Directory › UConn Health

Leslie A. Caromile, PhD

Assistant Professor of Cell Biology, Center for Vascular Biology


Academic Office Location: Center for Vascular Biology 263 Farmington Avenue, L5007 Farmington, CT 06030-3501
Phone:	860-679-1189
Email:	caromile@uchc.edu
Website(s):	Cell Biology Graduate Program

Education & Training
Committees & Organizations
Research
Lab Rotations
Publications
Presentations

Education

Degree	Institution	Major
BS	University of Connecticut	Physiology and Neurobiology
MS	California State University, Los Angeles	Biology
PhD	University of Washington, School of Medicine	Pathology - Mechanism of Disease

Degree

Institution

Major

University of Connecticut

Physiology and Neurobiology

California State University, Los Angeles

Biology

PhD

University of Washington, School of Medicine

Pathology - Mechanism of Disease

Awards

Name of Award/Honor	Awarding Organization
Mentor Award for Excellence in Mentoring	CICATS BUILDing Scholars Program
FRED (Faculty Research and Education Development) Fellow	American Society for Cell Biology

Name of Award/Honor

Awarding Organization

Mentor Award for Excellence in Mentoring

CICATS BUILDing Scholars Program

FRED (Faculty Research and Education Development) Fellow

American Society for Cell Biology

Name & Description	Category	Role	Type	Scope	Start Year	End Year
Society for the Advancement of Chicanos and Native Americans (SACNAS) undergraduate and graduate student abstract review for the 2020 SACNAS National Conference	Professional/Scientific Organization	Reviewer	External	National	2020	2020
Prostate Cancer UK	Study Section	Grant Reviewer	External	International	2020
Undergraduate Summer Research Internship Program in Biological and Biomedical Sciences	Research Committee	Director	UConn Health	University	2020
Prostate Cancer Foundation Tumorigenesis Working Group Leader.	Professional/Scientific Organization	Co-Director	External	International	2020
Graduate Admissions Committee	Education Committee	AOC Member	UConn Health	University	2019
Capstone Scholarly Project proposals	Other	Reviewer	UConn Health	University	2019
Doctoral Exam and Advisory Committee UCHC Biomedical Sciences Program, Center for Quantitative Medicine - Bandita Adhikari	Advisory Committee	Thesis Committee Member	UConn Health	University	2019	2020
Search Committee for UCONN Health Chair of Molecular Medicine and Biophysics	Advisory Committee	Advisory Member	UConn Health	International	2019	2020
Doctoral Exam and Advisory Committee of Sara Pan UCHC Biomedical Sciences Program, Dept. Cell Biology.	Advisory Committee	Committee Member	UConn Health	University	2017
Keystone Symposia Study Group Member	Study Section	Voting Member	External	International	2017
Biochemical Journal (BMC International) request for a manuscript review that involves PSMA	Professional/Scientific Journal	Invited Reviewer	External	International	2017
Theranostics Journal	Professional/Scientific Journal	Invited Reviewer	External	International	2017
Current Drug Targets Journal	Professional/Scientific Journal	Invited Reviewer	External	International	2017

Name & Description

Journal Articles

Single nucleotide polymorphisms and Zn transport by ZIP11 shape functional phenotypes of HeLa cells.
Kim, Elizabeth Y; Verdejo-Torres, Odette; Diaz-Rodriguez, Karla; Hasanain, Farah; Caromile, Leslie; Padilla-Benavides, Teresita Metallomics : integrated biometal science 2024 Jan;
Single nucleotide polymorphisms and Zn transport by nuclear ZIP11 shape cancer phenotype in HeLa cells. 2023.08.12.553076;
Elizabeth Y. Kim, Odette Verdejo-Torres, Karla Diaz Rodriguez, Farah Hasanain, Leslie Caromile, Teresita Padilla-Benavides. bioRxiv 2023 Aug;
Assessment of diversity-based approaches used by American Universities to increase recruitment and retention of biomedical sciences research faculty members: A scoping review protocol.
Petersen, Britta; Koshy-Chenthittayil, Sherli; DeArmond, Megan; Caromile, Leslie A PloS one 2023 Jan;18(6):e0276089
Assessment of diversity-based approaches used by American Universities to increase recruitment and retention of biomedical sciences faculty members: a scoping review protocol
Britta Petersen, Sherli Koshy-Chenthittayil, Leslie A. Caromile MedRxiv (Currently undergoing final revision at PLoS One, where it was peer-reviewed) 2022 Oct;
ZIP11 Regulates Nuclear Zinc Homeostasis in HeLa Cells and Is Required for Proliferation and Establishment of the Carcinogenic Phenotype.
Olea-Flores, Monserrat; Kan, Julia; Carlson, Alyssa; Syed, Sabriya A; McCann, Cat; Mondal, Varsha; Szady, Cecily; Ricker, Heather M; McQueen, Amy; Navea, Juan G; Caromile, Leslie A; Padilla-Benavides, Teresita Frontiers in Cell and Developmental Biology 2022 Jul;10895433
Murine Bone Exhibits Temporal Response to Metabolic Acidosis
Peterson Anna, Moody Mikayla, Wingender Brian, Morozov Katya, Nakashima Iris, Easson Margaret, Abraham Ron, Schmidt Tannin A., Caromile Leslie, and Deymier Alix. SSRN - (Currently undergoing revision at Journal of Structural Biology where it was peer-reviewed) 2022 May;
Prostate-Specific Membrane Antigen-Targeted Turn-on Probe for Imaging Cargo Release in Prostate Cancer Cells.
Olatunji, Feyisola P; Savoy, Emily A; Panteah, Mylan; Mesbahi, Nooshin; Abbasi, Armina; Talley, Cresencia M; Lovingier, Christine L; Caromile, Leslie A; Berkman, Clifford E Bioconjugate chemistry 2021 Oct;
The innate immune response to ischemic injury: a multiscale modeling perspective.
Dimitrova, Elena; Caromile, Leslie A; Laubenbacher, Reinhard; Shapiro, Linda H BMC systems biology 2018 Apr;12(1):50
PSMA redirects cell survival signaling from the MAPK to the PI3K-AKT pathways to promote the progression of prostate cancer.
Caromile, Leslie Ann; Dortche, Kristina; Rahman, M Mamunur; Grant, Christina L; Stoddard, Christopher; Ferrer, Fernando A; Shapiro, Linda H Science signaling 2017 Mar;10(470):
Molecular mechanisms regulating CD13-mediated adhesion.
Ghosh, Mallika; Gerber, Claire; Rahman, M Mamunur; Vernier, Kaitlyn M; Pereira, Flavia E; Subramani, Jaganathan; Caromile, Leslie A; Shapiro, Linda H Immunology 2014 Mar;142(4):636-47
Tyrosine phosphorylation of CD13 regulates inflammatory cell-cell adhesion and monocyte trafficking.
Subramani, Jaganathan; Ghosh, Mallika; Rahman, M Mamunur; Caromile, Leslie A; Gerber, Claire; Rezaul, Karim; Han, David K; Shapiro, Linda H Journal of immunology (Baltimore, Md. : 1950) 2013 Aug;191(7):3905-12
Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2 β: identification of miR-153 target genes with functions related to IA-2β in pancreas and brain.
Mandemakers, W; Abuhatzira, L; Xu, H; Caromile, L A; Hébert, S S; Snellinx, A; Morais, V A; Matta, S; Cai, T; Notkins, A L; De Strooper, B Diabetologia 2013 Jul;56(7):1547-56
Prostate specific membrane antigen (PSMA) regulates angiogenesis independently of VEGF during ocular neovascularization.
Grant, Christina L; Caromile, Leslie A; Ho, Vivienne; Durrani, Khayyam; Rahman, M Mamunur; Claffey, Kevin P; Fong, Guo-Hua; Shapiro, Linda H PloS one 2012 Jul;7(7):e41285
The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion.
Caromile, Leslie A; Oganesian, Anush; Coats, Scott A; Seifert, Ronald A; Bowen-Pope, Daniel F The Journal of biological chemistry 2010 Apr;285(14):10487-96
Contrasting role of presenilin-1 and presenilin-2 in neuronal differentiation in vitro.
Hong, C S; Caromile, L; Nomata, Y; Mori, H; Bredesen, D E; Koo, E H The Journal of neuroscience : the official journal of the Society for Neuroscience 1999 Jan;19(2):637-43
The Innate Immune Response to Ischemic Injury: a Multiscale Modeling Perspective
Elena Dimitrova, PhD; Leslie A. Caromile, PhD; Reinhard C Laubenbacher, PhD; Linda H. Shapiro BMC Systems Biology

Editorials

Systemic racism in higher education.
Barber, Paul H; Hayes, Tyrone B; Johnson, Tracy L; Márquez-Magaña, Leticia; 10,234 signatories (Leslie A. Caromile) Science (New York, N.Y.) 2020 Sep;369(6510):1440-1441

Newsletters

Be more like Harry: Creating inclusive spaces in STEM
Leslie A. Caromile American Society for Cell Biology Newsletter: Careers, Diversity Matters, Diversity, Equity, and Inclusion 2022 Aug;
Why do we still use the word “minority"?
Leslie Caromile American Society for Cell Biology: Careers, Diversity Matters, Diversity, Equity, and Inclusion 2022 Jun;

Reviews

How to Construct and Deliver an Elevator Pitch: A Recipe for the Research Scientist.
Caromile, L.A,, Jha, A., Gardiner, J., Dilek, O., Ohi, R., & Ligon, L. preprints.org 2023 Dec;
Therapeutic potential of targeting mirnas to prostate cancer tumors: using psma as an active target.
Yarahmadi, Amir; Sohan, Romoye; McAllister, Brenna; Caromile, Leslie A Molecular & Cellular Oncology 2022 Oct;9(1):2136476
PSMA redirects MAPK to PI3K-AKT signaling to promote prostate cancer progression.
Caromile, Leslie Ann; Shapiro, Linda H Molecular & cellular oncology 2017 Apr;4(4):e1321168

Title or Abstract	Type	Sponsor/Event	Date/Year	Location
PSMA: More than a diagnostic marker	Lecture	UMASS Boston, Dept of Biology	2019	UMASS Boston

Title or Abstract

Type

Sponsor/Event

Date/Year

Location

PSMA: More than a diagnostic marker

Lecture

UMASS Boston, Dept of Biology

2019

UMASS Boston