Manuel A. Castro-Alamancos, PhDProfessor of NeuroscienceJanice and Rodney Reynolds Endowed Chair of Neurobiology
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Education
Post-Graduate Training
Degree | Institution | Major |
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BSc | University Complutense | Psychology |
MSc | Cajal Institute (CSIC) and University Complutense | Neuroscience |
PhD | Cajal Institute (CSIC) and University Complutense | Neuroscience |
Post-Graduate Training
Training | Institution | Specialty |
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Postdoctoral | Brown University | Research Associate, Department of Neuroscience |
The synaptic, cellular and network mechanisms involved in sensorimotor information transmission, coding and storage during motivated behaviors.
Accepting Lab Rotation Students: Fall Block 2024, Spring 1 and 2 Block 2025
Journal Articles
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Role of the Nucleus Accumbens in Signaled Avoidance Actions.
eNeuro 2024 Oct;11(10):
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Zona incerta distributes a broad movement signal that modulates behavior.
eLife 2023 Dec;12
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The orienting reflex reveals behavioral states set by demanding contexts: role of the superior colliculus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Feb;
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Caution influences avoidance and approach behaviors differently.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Jun;
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A System to Easily Manage Metadata in Biomedical Research Labs Based on Open-source Software.
Bio-protocol 2022 May;12(9):e4404
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Bidirectional control of orienting behavior by the substantia nigra pars reticulata: distinct significance of head and whisker movements.
eNeuro 2021 Sep;
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A signaled locomotor avoidance action is fully represented in the neural activity of the midbrain tegmentum.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Mar;
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Basal ganglia output has a permissive non-driving role in a signaled locomotor action mediated by the midbrain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Dec;
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Circuits That Mediate Expression of Signaled Active Avoidance Converge in the Pedunculopontine Tegmentum.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Jun;39(23):4576-4594
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Basal Ganglia Output Controls Active Avoidance Behavior.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Oct;36(40):10274-10284
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Whisker-related afferents in superior colliculus.
Journal of neurophysiology 2016 May;115(5):2265-79
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NMDA receptors are the basis for persistent network activity in neocortex slices.
Journal of neurophysiology 2015 Jun;113(10):3816-26
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Modulation of artificial whisking related signals in barrel cortex.
Journal of neurophysiology 2015 Mar;113(5):1287-301
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Neuromodulators produce distinct activated states in neocortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Sep;34(37):12353-67
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Neuromodulation of whisking related neural activity in superior colliculus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 May;34(22):7683-95
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Synaptic cooperativity regulates persistent network activity in neocortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Feb;33(7):3151-63
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The motor cortex: a network tuned to 7-14 Hz.
Frontiers in neural circuits 2013 Jan;721
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The state of somatosensory cortex during neuromodulation.
Journal of neurophysiology 2012 Aug;108(4):1010-24
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Superior colliculus cells sensitive to active touch and texture during whisking.
Journal of neurophysiology 2011 Jul;106(1):332-46
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Vibrissal midbrain loops.
Scholarpedia journal. 2011 Jun;6(6):7274
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Effects of cortical activation on sensory responses in barrel cortex.
Journal of neurophysiology 2011 Apr;105(4):1495-505
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Behavioral state dependency of neural activity and sensory (whisker) responses in superior colliculus.
Journal of neurophysiology 2010 Sep;104(3):1661-72
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Neural correlates of active avoidance behavior in superior colliculus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Jun;30(25):8502-11
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Vibrissal thalamic modes.
Scholarpedia journal. 2010 May;5(7):7278
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Neocortex network activation and deactivation states controlled by the thalamus.
Journal of neurophysiology 2010 Mar;103(3):1147-57
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Detection of low salience whisker stimuli requires synergy of tectal and thalamic sensory relays.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Feb;30(6):2245-56
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Cortical up and activated states: implications for sensory information processing.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2009 Dec;15(6):625-34
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Impact of persistent cortical activity (up States) on intracortical and thalamocortical synaptic inputs.
Journal of neurophysiology 2009 Jul;102(1):119-31
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Influence of subcortical inhibition on barrel cortex receptive fields.
Journal of neurophysiology 2009 Jul;102(1):437-50
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Vibrissa sensation in superior colliculus: wide-field sensitivity and state-dependent cortical feedback.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Oct;28(44):11205-20
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Cortical transformation of wide-field (multiwhisker) sensory responses.
Journal of neurophysiology 2008 Jul;100(1):358-70
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Area-specific resonance of excitatory networks in neocortex: control by outward currents.
Epilepsia 2007 Aug;48(8):1572-84
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Early sensory pathways for detection of fearful conditioned stimuli: tectal and thalamic relays.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Jul;27(29):7762-76
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Thalamocortical Up states: differential effects of intrinsic and extrinsic cortical inputs on persistent activity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Apr;27(16):4261-72
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What generates whisking? Focus on: "The whisking rhythm generator: a novel mammalian network for the generation of movement".
Journal of neurophysiology 2007 Mar;97(3):1883-4
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Zona Incerta GABAergic Output Controls a Signaled Locomotor Action in the Midbrain Tegmentum.
eNeuro 7(1):
Book Chapters
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The whisker thalamus.
Sensorimotor Integration in the Whisker System 2015 Jan;Chapter 2; p.31-58