Photo of Breno Satler Diniz, M.D., Ph.D.

Breno Satler Diniz, M.D., Ph.D.

Associate Professor of Psychiatry
Academic Office Location:
UConn Center on Aging
UConn Health
263 Farmington Avenue
Farmington, CT 06030-5215
Phone: 860-679-2476

UConn Center on Aging

Department of Psychiatry

Neuroscience Graduate Program

Cell Biology Graduate Program

M.D.Federal University of Minas GeraisMedicine
Ph.D.University of São Paulo Department and Institute of PsychiatryNeurobiology of Late-life Depression and Alzheimer's Disease

Post-Graduate Training
PostdoctoralUniversity of Pittsburgh School of MedicineMajor Subject: Discovery of Peripheral and Central Biomarkers Signature of Cognitive Impairment in Late-life Depression.
ResidencyUniversity of São PauloGeneral Psychiatry, Department and Institute of Psychiatry
FellowshipUniversity of São PauloGeriatric Psychiatry, Department and Institute of Psychiatry

Name of Award/HonorAwarding Organization
Labatt Professorship in Biology of DepressionUniversity of Toronto
Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
Society of Biological PsychiatryResearch CommitteeMemberExternalNational2022
American Association for Geriatric PsychiatryResearch CommitteeMemberExternalNational2022
The Adult Psychopathology and Disorders of Aging (APDA) Study Section, NIHStudy SectionPermanent MemberExternalNational20222026
Research Council - UCHCAdvisory CommitteePermanent MemberUConn HealthUniversity20222025
The Mechanisms of Emotion, Stress and Health (MESH) study section, NIHStudy SectionTemporary MemberExternalNational20212021
American College of NeuropsychopharmacologyEducation CommitteeMemberExternalNational2020
American Journal of Geriatric PsychiatryEditorial BoardEditorial board memberExternalNational2020
Brazilian Psychiatric AssociationMemberInternational20072015

Dr. Diniz lab is focused on investigating how age-related changes in biological processes (the Pillars of Biological Aging) affect the development and outcomes of late-life mental and neuropsychiatric disorders and how it translates into the repurpose or development of novel interventions to treat and prevent these disorders across the lifespan. This is a new area of investigation combining a fundamental aspects of Geroscience and Neurobiology of Neuropsychiatric disorders. Dr. Diniz uses a translational medicine approach, including the evaluation of multimodal biomarkers, focusing on peripheral and central biomarkers, combined with complex analytical approaches to address different research questions related to the interaction between the biology of aging and neuropsychiatric disorders.

Accepting Lab Rotation Students: Summer 2022, Fall 2022, and Spring 2023

Journal Articles



Title or AbstractTypeSponsor/EventDate/YearLocation
Cellular Senescence Abnormalities in Late-Life Depression.LectureBiology of Healthy Aging Grand Round2023John Hopkins University
Investigating Biomarkers in Late-Life Cognitive and Neuropsychiatric DisordersLectureDepartment of Psychiatry, UConn School of Medicine2022UConn Health
Cellular and molecular senescence in late-life depressionLectureNewcastle University, UK2022
. Cellular and molecular markers of senescence in geriatric depressionPlenary LectureVII Congress of Clinical Psychiatry2022Sao Paulo, Brazil
The importance of diet to aging and prevention of dementia.Plenary LectureGut and Brain Congress2022Sao Paulo, Brazil
SASP markers and treatment outcomes in older adults with major depressive disorderLectureNIA, San Antonio Nathan Shock Center/2022 Masoro-Barshop Conference on Agin2022San Antonio, TX
Accelerated Biological aging: A Geroscience-Focus Approach to Understanding Brain Health and Late-Life Psychiatric Disorders Mechanisms and OutcomesOther2022 Annual Meeting, Society of Biological Psychiatry2022New Orleans, La