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Meta-analysis identifies common gut microbiota associated with multiple sclerosis.
Lin, Qingqi; Dorsett, Yair; Mirza, Ali; Tremlett, Helen; Piccio, Laura; Longbrake, Erin E; Choileain, Siobhan Ni; Hafler, David A; Cox, Laura M; Weiner, Howard L; Yamamura, Takashi; Chen, Kun; Wu, Yufeng; Zhou, Yanjiao Genome medicine 2024 Jul;16(1):94
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Short-chain fatty acid valerate reduces voluntary alcohol intake in male mice.
Bokoliya, Suresh C; Russell, Jordan; Dorsett, Yair; Panier, Hunter A; Singh, Vijender; Daddi, Lauren; Yuan, Hanshu; Dedon, Liv R; Liu, Zhongmao; Zhou, Yuqi; Min, Zefang; Barson, Jessica R; Covault, Jonathan; Bubier, Jason A; Zhou, Yanjiao Microbiome 2024 Jun;12(1):108
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Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease.
Zhou, Xin; Shen, Xiaotao; Johnson, Jethro S; Spakowicz, Daniel J; Agnello, Melissa; Zhou, Wenyu; Avina, Monica; Honkala, Alexander; Chleilat, Faye; Chen, Shirley Jingyi; Cha, Kexin; Leopold, Shana; Zhu, Chenchen; Chen, Lei; Lyu, Lin; Hornburg, Daniel; Wu, Si; Zhang, Xinyue; Jiang, Chao; Jiang, Liuyiqi; Jiang, Lihua; Jian, Ruiqi; Brooks, Andrew W; Wang, Meng; Contrepois, Kévin; Gao, Peng; Rose, Sophia Miryam Schüssler-Fiorenza; Tran, Thi Dong Binh; Nguyen, Hoan; Celli, Alessandra; Hong, Bo-Young; Bautista, Eddy J; Dorsett, Yair; Kavathas, Paula B; Zhou, Yanjiao; Sodergren, Erica; Weinstock, George M; Snyder, Michael P Cell host & microbe 2024 Mar;
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Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease.
Zhou, Xin; Shen, Xiaotao; Johnson, Jethro S; Spakowicz, Daniel J; Agnello, Melissa; Zhou, Wenyu; Avina, Monica; Honkala, Alexander; Chleilat, Faye; Chen, Shirley Jingyi; Cha, Kexin; Leopold, Shana; Zhu, Chenchen; Chen, Lei; Lyu, Lin; Hornburg, Daniel; Wu, Si; Zhang, Xinyue; Jiang, Chao; Jiang, Liuyiqi; Jiang, Lihua; Jian, Ruiqi; Brooks, Andrew W; Wang, Meng; Contrepois, Kévin; Gao, Peng; Schüssler-Fiorenza Rose, Sophia Miryam; Binh Tran, Thi Dong; Nguyen, Hoan; Celli, Alessandra; Hong, Bo-Young; Bautista, Eddy J; Dorsett, Yair; Kavathas, Paula; Zhou, Yanjiao; Sodergren, Erica; Weinstock, George M; Snyder, Michael P bioRxiv : the preprint server for biology. Cell Host & Microbe - under review. 2024 Feb;
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Short-chain-fatty acid valerate reduces voluntary alcohol intake in male mice.
Bokoliya, Suresh C; Russell, Jordan; Dorsett, Yair; Panier, Hunter; Singh, Vijender; Daddi, Lauren; Yuan, Hanshu; Dedon, Liv R; Liu, Zhongmao; Barson, Jessica R; Covault, Jonathan; Bubier, Jason A; Zhou, Yanjiao Res Sq. Accepted in Microbiome. 2023 Oct;TBD(TBD):TBD
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Baseline Gut Microbiome Signatures Correlate with Immunogenicity of SARS-CoV-2 mRNA Vaccines.
Daddi, Lauren; Dorsett, Yair; Geng, Tingting; Bokoliya, Suresh; Yuan, Hanshu; Wang, Penghua; Xu, Wanli; Zhou, Yanjiao International journal of molecular sciences 2023 Jul;24(14):
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Exploratory studies of oral and fecal microbiome in healthy human aging.
Zhou, Xin; Wang, Baohong; Demkowicz, Patrick C; Johnson, Jethro S; Chen, Yanfei; Spakowicz, Daniel J; Zhou, Yanjiao; Dorsett, Yair; Chen, Lei; Sodergren, Erica; Kuchel, George A; Weinstock, George M Frontiers in aging 2022 Oct;31002405
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Subgenomic RNA profiling suggests novel mechanism in coronavirus gene regulation and host adaption.
Lyu, Lin; Feng, Ru; Zhang, Mingnan; Xie, Xiaoqing; Liao, Yinjing; Zhou, Yanjiao; Guo, Xiaokui; Su, Bing; Dorsett, Yair; Chen, Lei Life science alliance 2022 Aug;5(8):
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Effects of dietary restriction on gut microbiota and CNS autoimmunity.
Cantoni, Claudia; Dorsett, Yair; Fontana, Luigi; Zhou, Yanjiao; Piccio, Laura Clinical Immunology 2022 Feb;235108575
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Alterations of host-gut microbiome interactions in multiple sclerosis.
Cantoni, Claudia; Lin, Qingqi; Dorsett, Yair; Ghezzi, Laura; Liu, Zhongmao; Pan, Yeming; Chen, Kun; Han, Yanhui; Li, Zhengze; Xiao, Hang; Gormley, Matthew; Liu, Yue; Bokoliya, Suresh; Panier, Hunter; Suther, Cassandra; Evans, Emily; Deng, Li; Locca, Alberto; Mikesell, Robert; Obert, Kathleen; Newland, Pamela; Wu, Yufeng; Salter, Amber; Cross, Anne H; Tarr, Phillip I; Lovett-Racke, Amy; Piccio, Laura; Zhou, Yanjiao EBioMedicine 2022 Jan;76103798
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Alterations of the gut mycobiome in patients with MS.
Shah, Saumya; Locca, Alberto; Dorsett, Yair; Cantoni, Claudia; Ghezzi, Laura; Lin, Qingqi; Bokoliya, Suresh; Panier, Hunter; Suther, Cassandra; Gormley, Matthew; Liu, Yue; Evans, Emily; Mikesell, Robert; Obert, Kathleen; Salter, Amber; Cross, Anne H; Tarr, Phillip I; Lovett-Racke, Amy; Piccio, Laura; Zhou, Yanjiao EBioMedicine 2021 Aug;71103557
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Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota.
Cignarella, Francesca; Cantoni, Claudia; Ghezzi, Laura; Salter, Amber; Dorsett, Yair; Chen, Lei; Phillips, Daniel; Weinstock, George M; Fontana, Luigi; Cross, Anne H; Zhou, Yanjiao*; Piccio, Laura* Cell metabolism 2018 Jun;27(6):1222-1235.e6 *Co-Corresponding Authors
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HCoDES reveals chromosomal DNA end structures with single-nucleotide resolution.
Dorsett, Yair; Zhou, Yanjiao; Tubbs, Anthony T; Chen, Bo-Ruei; Purman, Caitlin; Lee, Baeck-Seung; George, Rosmy; Bredemeyer, Andrea L; Zhao, Jiang-Yang; Sodergen, Erica; Weinstock, George M; Han, Nathan D; Reyes, Alejandro; Oltz, Eugene M; Dorsett, Dale; Misulovin, Ziva; Payton, Jacqueline E; Sleckman, Barry P Molecular cell 2014 Dec;56(6):808-18
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KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G₁-phase lymphocytes.
Tubbs, Anthony T; Dorsett, Yair; Chan, Elizabeth; Helmink, Beth; Lee, Baeck-Seung; Hung, Putzer; George, Rosmy; Bredemeyer, Andrea L; Mittal, Anuradha; Pappu, Rohit V; Chowdhury, Dipanjan; Mosammaparast, Nima; Krangel, Michael S; Sleckman, Barry P Molecular and cellular biology 2014 Aug;34(15):2811-21
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Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination.
Lee, Baeck-Seung; Gapud, Eric J; Zhang, Shichuan; Dorsett, Yair; Bredemeyer, Andrea; George, Rosmy; Callen, Elsa; Daniel, Jeremy A; Osipovich, Oleg; Oltz, Eugene M; Bassing, Craig H; Nussenzweig, Andre; Lees-Miller, Susan; Hammel, Michal; Chen, Benjamin P C; Sleckman, Barry P Molecular and cellular biology 2013 Sep;33(18):3568-79
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Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation.
Gapud, Eric J; Dorsett, Yair; Yin, Bu; Callen, Elsa; Bredemeyer, Andrea; Mahowald, Grace K; Omi, Kazuo Q; Walker, Laura M; Bednarski, Jeffrey J; McKinnon, Peter J; Bassing, Craig H; Nussenzweig, Andre; Sleckman, Barry P Proceedings of the National Academy of Sciences of the United States of America 2011 Feb;108(5):2022-7
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H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes.
Helmink, Beth A; Tubbs, Anthony T; Dorsett, Yair; Bednarski, Jeffrey J; Walker, Laura M; Feng, Zhihui; Sharma, Girdhar G; McKinnon, Peter J; Zhang, Junran; Bassing, Craig H; Sleckman, Barry P Nature 2011 Jan;469(7329):245-9
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Role of the translocation partner in protection against AID-dependent chromosomal translocations.
Jankovic, Mila; Robbiani, Davide F; Dorsett, Yair; Eisenreich, Thomas; Xu, Yang; Tarakhovsky, Alexander; Nussenzweig, Andre; Nussenzweig, Michel C Proceedings of the National Academy of Sciences of the United States of America 2010 Jan;107(1):187-92
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AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations.
Robbiani, Davide F; Bothmer, Anne; Callen, Elsa; Reina-San-Martin, Bernardo; Dorsett, Yair; Difilippantonio, Simone; Bolland, Daniel J; Chen, Hua Tang; Corcoran, Anne E; Nussenzweig, André; Nussenzweig, Michel C Cell 2008 Dec;135(6):1028-38
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MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation.
Dorsett, Yair; McBride, Kevin M; Jankovic, Mila; Gazumyan, Anna; Thai, To-Ha; Robbiani, Davide F; Di Virgilio, Michela; Reina San-Martin, Bernardo; Heidkamp, Gordon; Schwickert, Tanja A; Eisenreich, Thomas; Rajewsky, Klaus; Nussenzweig, Michel C Immunity 2008 May;28(5):630-8
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Haploinsufficiency of activation-induced deaminase for antibody diversification and chromosome translocations both in vitro and in vivo.
Sernández, Isora V; de Yébenes, Virginia G; Dorsett, Yair; Ramiro, Almudena R PloS one 2008 Jan;3(12):e3927
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A role for AID in chromosome translocations between c-myc and the IgH variable region.
Dorsett, Yair; Robbiani, Davide F; Jankovic, Mila; Reina-San-Martin, Bernardo; Eisenreich, Thomas R; Nussenzweig, Michel C The Journal of experimental medicine 2007 Sep;204(9):2225-32
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Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.
Meister, Gunter; Landthaler, Markus; Patkaniowska, Agnieszka; Dorsett, Yair; Teng, Grace; Tuschl, Thomas Molecular cell 2004 Jul;15(2):185-97
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siRNAs: applications in functional genomics and potential as therapeutics.
Dorsett, Yair; Tuschl, Thomas Nature reviews. Drug discovery 2004 Apr;3(4):318-29
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Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing.
Meister, Gunter; Landthaler, Markus; Dorsett, Yair; Tuschl, Thomas RNA (New York, N.Y.) 2004 Mar;10(3):544-50
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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo.
Hawiger, D; Inaba, K; Dorsett, Y; Guo, M; Mahnke, K; Rivera, M; Ravetch, J V; Steinman, R M; Nussenzweig, M C The Journal of experimental medicine 2001 Sep;194(6):769-79