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Laura Haynes, PhD FGSAProfessor, ImmunologyUConn Center on Aging
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- Education & Training
- Teaching
- Committees & Organizations
- Research
- Lab Rotations
- Publications
- Presentations
Education
Post-Graduate Training
| Degree | Institution | Major |
|---|---|---|
| BS | University of Miami | Biology |
| MS | University of Miami School of Medicine | Immunology |
| PhD | University of Rochester School of Medicine | Immunology |
Post-Graduate Training
| Training | Institution | Specialty |
|---|---|---|
| Fellowship | NIH Predoctoral Immunology Training Grant Fellowship | |
| Postdoctoral | UCSD | Research Fellow, Department of Biology |
| Fellowship | NIH Postdoctoral Immunology Training Grant Fellowship | |
| Postdoctoral | Trudeau Institute | Research Scientist |
Dr. Haynes is co-director of Medical Microbiology MEDS-6444 and also she also teaches in Advanced Molecular and Cellular Immunology MEDS-5335.
| Name & Description | Category | Role | Type | Scope | Start Year | End Year |
|---|---|---|---|---|---|---|
| Systems Immunology in Aging and Complex Diseases: organizing committee member and chair of “Cancer and Aging” session | Workshop/Conference | Organizer | External | International | 2023 | |
| Field Chief Editor, Frontiers in Aging | Professional/Scientific Journal | Editor | External | International | 2022 | |
| Deputy Editor, Journal of Gerontology series A | Professional/Scientific Journal | Associate Editor | External | International | 2022 | |
| Gerontological Society of America | Professional/Scientific Organization | Board of Directors (elected member) | External | International | 2022 | |
| Patterson Foundation-grant reviewer | Study Section | Member | External | Regional | 2020 | |
| Advisory board for R33 Translational Geroscience Network grant | Advisory Committee | Member | External | National | 2019 | |
| UConn Health Senior Appointments and Promotions Committee | Other | member | UConn Health | University | 2016 | |
| Gerontological Society of America | Professional/Scientific Organization | member | External | National | 2016 | |
| UConn Health Committee on Biohazards | Research Committee | Chair | UConn Health | University | 2015 | 2023 |
| Member NIH/NIAID Review Panel Vaccines against Microbial Disease | Study Section | member | External | National | 2014 | 2020 |
| UConn Health Center IACUC member | Research Committee | member | UConn Health | University | 2013 | |
| American Foundation for Aging Research | Advisory Committee | Advisory Board Member | External | National | 2002 | |
| American Association of Immunologists | Professional/Scientific Organization | Member | External | National | 1999 |
Dr. Laura Haynes is a prominent figure in the field of immunology, particularly in the context of aging and its effects on immune responses. As a tenured Professor in the Center on Aging and the Department of Immunology at the University of Connecticut School of Medicine, she brings a wealth of knowledge and experience to her research endeavors. Her primary focus lies in understanding how the aging process influences the immune system's ability to respond to infections and vaccinations. This area of study is crucial, given the increased susceptibility of older individuals to infectious diseases and the importance of vaccination in mitigating these risks.
One key aspect of her research is the exploration of senescent cells and their role in immune function during aging. Senescent cells are cells that have stopped dividing and are associated with aging and age-related diseases. Understanding how these cells impact immune responses can provide valuable insights into developing strategies to enhance vaccination efficacy and improve overall immune health in older adults. Through her work, Dr. Haynes contributes significantly to advancing our understanding of the complex interplay between aging, the immune system, and infectious diseases. Her findings have the potential to inform the development of novel interventions and therapies aimed at promoting healthy aging and reducing the burden of age-related infections.
Not Accepting Lab Rotation Students at this time
Available rotation projects in the Haynes laboratory include studies on influenza, aging, and senescence.
Journal Articles
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Intermittent clearance of p21-highly-expressing cells extends lifespan and confers sustained benefits to health and physical function.
Cell Metabolism. 2024 Aug;36(8):1795-1805.e6
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UBXN3B is crucial for B lymphopoiesis.
EBioMedicine 2024 Jul;106105248
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Cellular senescence is a double-edged sword in regulating aged immune responses to influenza.
Aging cell 2024 Apr;e14162
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Unraveling the association between major depressive disorder and senescent biomarkers in immune cells of older adults: a single-cell phenotypic analysis.
Frontiers in aging 2024 Jan;51376086
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NK- and T-cell granzyme B and K expression correlates with age, CMV infection and influenza vaccine-induced antibody titres in older adults.
Frontiers in Aging. 2023 Jan;31098200
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Altered T cell infiltration and enrichment of leukocyte regulating pathways within aged skeletal muscle are associated impaired muscle function following influenza infection.
GeroScience 2022 Dec;
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Advanced biological age is associated with improved antibody responses in older high-dose influenza vaccine recipients over four consecutive seasons.
Immunity & Ageing. 2022 Aug;19(1):39
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Markers of systemic inflammation are positively associated with influenza vaccine antibody responses with a possible role for ILT2(+)CD57(+) NK-cells.
Immunity and Ageing. 2022 May;19(1):26
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Cellular senescence is a key mediator of lung aging and susceptibility to infection.
Frontiers in immunology 2022 Jan;131006710
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Senescence-induced changes in CD4 T cell differentiation can be alleviated by treatment with senolytics.
Aging cell 2022 Jan;e13525
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Sex differences in susceptibility to influenza A virus infection depend on host genotype.
PloS one 2022 Jan;17(9):e0273050
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An inducible p21-Cre mouse model to monitor and manipulate p21-highly-expressing senescent cells in vivo.
Nature Aging. 2021 Oct;1(10):962-973
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An Essential Role of UBXN3B in B Lymphopoiesis.
bioRxiv : the preprint server for biology 2021 Aug;
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Targeting Aging: Lessons Learned From Immunometabolism and Cellular Senescence.
Frontiers in Immunology 2021 Jul;12
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Moving geroscience from the bench to clinical care and health policy.
Journal of the American Geriatrics Society 2021 Jun;
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Antibody and Cell-Mediated Immune Responses Are Correlates of Protection against Influenza Infection in Vaccinated Older Adults.
Vaccines 2021 Jan;9(1):
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Targeting Aging: Lessons Learned From Immunometabolism and Cellular Senescence.
Frontiers in immunology 2021 Jan;12714742
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Vaccination of aged mice with adjuvanted recombinant influenza nucleoprotein enhances protective immunity.
Vaccine 2020 Jul;38(33):5256-5267
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Influenza infection has fiber type-specific effects on cellular and molecular skeletal muscle function in aged mice.
The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Jun;
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Age-related factors that affect B cell responses to vaccination in mice and humans.
Immunological reviews 2020 Jun;
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Vaccination mitigates influenza-induced muscular declines in aged mice.
GeroScience 2020 May;
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Frailty Is Associated With Increased Hemagglutination-Inhibition Titers in a 4-Year Randomized Trial Comparing Standard- and High-Dose Influenza Vaccination.
Open forum infectious diseases 2020 May;7(5):ofaa148
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Influenza Vaccination: Accelerating the Process for New Vaccine Development in Older Adults.
Interdisciplinary topics in gerontology and geriatrics 2020 Jan;4398-112
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Protective Intranasal Immunization Against Influenza Virus in Infant Mice Is Dependent on IL-6.
Frontiers in immunology 2020 Jan;11568978
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The immune response to influenza in older humans: beyond immune senescence.
Immunity & ageing : I & A 2020 Jan;1710
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Diminished immune responses with aging predispose older adults to common and uncommon influenza complications.
Cellular immunology 2019 Oct;103992
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Assessment of lymph node stromal cells as an underlying factor in age-related immune impairment.
The journals of gerontology. Series A, Biological sciences and medical sciences 2019 Feb;
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A Relationship Between Blood Levels of Otolin-1 and Vitamin D.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2018 Apr;39(4):e269-e273
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Improved Immune Responses in Young and Aged Mice with Adjuvanted Vaccines against H1N1 Influenza Infection.
Frontiers in immunology 2018 Jan;9295
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Age-related Increase in Blood Levels of Otolin-1 in Humans.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2017 May;38865-869
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Impact of Age, Caloric Restriction, and Influenza Infection on Mouse Gut Microbiome: An Exploratory Study of the Role of Age-Related Microbiome Changes on Influenza Responses.
Frontiers in immunology 2017 Jan;81164
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IL-6 promotes the differentiation of a subset of naive CD8+ T cells into IL-21-producing B helper CD8+ T cells.
The Journal of experimental medicine 2016 Sep;2132281-2291
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IL-2 and IL-6 cooperate to enhance the generation of influenza-specific CD8 T cells responding to live influenza virus in aged mice and humans.
Oncotarget 2016 Jun;739171-39183
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Fine-Tuning of CD8(+) T Cell Mitochondrial Metabolism by the Respiratory Chain Repressor MCJ Dictates Protection to Influenza Virus.
Immunity 2016 May;441299-311
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Aging augments the impact of influenza respiratory tract infection on mobility impairments, muscle-localized inflammation, and muscle atrophy.
Aging 2016 Feb;8620-35
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Age-related impairment of humoral response to influenza is associated with changes in antigen specific T follicular helper cell responses.
Scientific reports 2016 Jan;625051
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Acute Plasmodium chabaudi infection dampens humoral responses to a secondary T-dependent antigen but enhances responses to a secondary T-independent antigen.
Journal of immunology (Baltimore, Md. : 1950) 2013 Sep;191(9):4731-9
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Immunity to the conserved influenza nucleoprotein reduces susceptibility to secondary bacterial infections.
Journal of immunology (Baltimore, Md. : 1950) 2012 Nov;189(10):4921-9
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Maintenance of peripheral T cell responses during Mycobacterium tuberculosis infection.
Journal of immunology (Baltimore, Md. : 1950) 2012 Nov;189(9):4451-8
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Aged-related shifts in T cell homeostasis lead to intrinsic T cell defects.
Seminars in immunology 2012 Oct;24(5):350-5
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Essential role of IL-6 in protection against H1N1 influenza virus by promoting neutrophil survival in the lung.
Mucosal immunology 2012 May;5(3):258-66
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Interdisciplinary critique of sipuleucel-T as immunotherapy in castration-resistant prostate cancer.
Journal of the National Cancer Institute 2012 Feb;104(4):273-9
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GLA-SE, a synthetic toll-like receptor 4 agonist, enhances T-cell responses to influenza vaccine in older adults.
The Journal of infectious diseases 2012 Feb;205(3):466-73
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Aging of the CD4 T Cell Compartment
Open Longevity Science 2012 Jan;683-91
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Extrinsic Factors Contribute to Age-Related Defects in CD4 T Cell Response
Aging Cell 2012 Jan;11732
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Live attenuated influenza vaccine (LAIV) impacts innate and adaptive immune responses.
Vaccine 2011 Oct;29(44):7849-56
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Age-related Deficiencies in Antigen-Specific CD4 T cell Responses: Lessons from Mouse Models.
Aging and disease 2011 Oct;2(5):374-81
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Regulation of antinucleoprotein IgG by systemic vaccination and its effect on influenza virus clearance.
Journal of virology 2011 May;85(10):5027-35
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Contributions of antinucleoprotein IgG to heterosubtypic immunity against influenza virus.
Journal of immunology (Baltimore, Md. : 1950) 2011 Apr;186(7):4331-9
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Workshop on immunizations in older adults: identifying future research agendas.
Journal of the American Geriatrics Society 2010 Apr;58(4):765-76
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Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects.
Proceedings of the National Academy of Sciences of the United States of America 2009 Oct;106(43):18333-8
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Effects of aging on T cell function.
Current opinion in immunology 2009 Aug;21(4):414-7
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CD28 and inducible costimulator (ICOS) signalling can sustain CD154 expression on activated T cells.
Immunology 2009 Jul;127(3):373-85
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T-cell immunosenescence: lessons learned from mouse models of aging.
Trends in immunology 2009 Jul;30(7):301-5
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Proinflammatory adjuvants enhance the cognate helper activity of aged CD4 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2009 May;182(10):6129-35
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The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells.
The Journal of experimental medicine 2009 Jan;206(1):69-78
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CD4+ T cells and immunosenescence--a mini-review.
Gerontology 2009 Jan;55(5):491-5
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IP3 receptor-mediated Ca2+ release in naive CD4 T cells dictates their cytokine program.
Journal of immunology (Baltimore, Md. : 1950) 2008 Dec;181(12):8315-22
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Bone marrow precursor cells from aged mice generate CD4 T cells that function well in primary and memory responses.
Journal of immunology (Baltimore, Md. : 1950) 2008 Oct;181(7):4825-31
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Impact of post-thymic cellular longevity on the development of age-associated CD4+ T cell defects.
Journal of immunology (Baltimore, Md. : 1950) 2008 Apr;180(7):4465-75
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Mentoring and networking: how to make it work.
Nature immunology 2008 Jan;9(1):3-5
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How vaccines work on the background of the aging immune system.
Experimental gerontology 2007 May;42(5):438-40
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Accumulation of NFAT mediates IL-2 expression in memory, but not naïve, CD4+ T cells.
Proceedings of the National Academy of Sciences of the United States of America 2007 Apr;104(17):7175-80
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IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge.
Nature immunology 2007 Apr;8(4):369-77
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Murine [corrected] myeloid dendritic cell-dependent toll-like receptor immunity is preserved with aging.
Aging cell 2006 Dec;5(6):473-86
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Lab management: insights for the new investigator.
Nature immunology 2006 Sep;7(9):895-7
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Antigen presentation and the regulation of CD4 memory generation to influenza.
Expert review of clinical immunology 2006 Jul;2(4):601-11
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Why aging T cells fail: implications for vaccination.
Immunity 2006 Jun;24(6):663-6
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Homeostasis and the age-associated defect of CD4 T cells.
Seminars in immunology 2005 Oct;17(5):370-7
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The effect of aging on cognate function and development of immune memory.
Current opinion in immunology 2005 Oct;17(5):476-9
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Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation.
The Journal of experimental medicine 2005 Sep;202(5):697-706
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Impaired CD4 T cell cognate function is responsible for age-related reductions in humoral responses.
Experimental lung research 2005 Sep;31 Suppl 1(1):78
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Gamma interferon-induced T-cell loss in virulent Mycobacterium avium infection.
Infection and immunity 2005 Jun;73(6):3577-86
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The effect of age on the cognate function of CD4+ T cells.
Immunological reviews 2005 Jun;205220-8
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Repeated stimulation of CD4 effector T cells can limit their protective function.
The Journal of experimental medicine 2005 Apr;201(7):1101-12
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Newly generated CD4 T cells in aged animals do not exhibit age-related defects in response to antigen.
The Journal of experimental medicine 2005 Mar;201(6):845-51
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IL-7: maintaining T-cell memory and achieving homeostasis.
Trends in immunology 2005 Mar;26(3):172-6
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Aging and immune function. Summary of a workshop held at Trudeau Institute, Saranac Lake, NY.
Mechanisms of ageing and development 2005 Jan;126(6-7):822-5
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Age-related defects in CD4 T cell cognate helper function lead to reductions in humoral responses.
The Journal of experimental medicine 2004 Dec;200(12):1613-22
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Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2004 May;172(9):5194-9
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CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly.
Proceedings of the National Academy of Sciences of the United States of America 2003 Dec;100(25):15053-8
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Reliable generation and use of MHC class II:gamma2aFc multimers for the identification of antigen-specific CD4(+) T cells.
Journal of immunological methods 2002 Dec;271(1-2):137-51
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The biological outcome of CD40 signaling is dependent on the duration of CD40 ligand expression: reciprocal regulation by interleukin (IL)-4 and IL-12.
The Journal of experimental medicine 2002 Sep;196(5):693-704
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Effect of age on naive CD4 responses: impact on effector generation and memory development.
Springer seminars in immunopathology 2002 Jan;24(1):53-60
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Reciprocal regulation of polarized cytokine production by effector B and T cells.
Nature immunology 2000 Dec;1(6):475-82
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Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells.
The Journal of experimental medicine 2000 Jul;192(1):117-22
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The defects in effector generation associated with aging can be reversed by addition of IL-2 but not other related gamma(c)-receptor binding cytokines.
Vaccine 2000 Feb;18(16):1649-53
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Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice.
The Journal of experimental medicine 1999 Oct;190(7):1013-24
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From naive to effector--alterations with aging.
Immunological reviews 1997 Dec;160(1):9-18
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Age-related changes in CD4 T cells of T cell receptor transgenic mice.
Mechanisms of ageing and development 1997 Feb;93(1-3):95-105
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Antigen-independent changes in naive CD4 T cells with aging.
The Journal of experimental medicine 1996 Nov;184(5):1891-900
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From naive to memory T cells.
Immunological reviews 1996 Apr;150(1):143-67
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Further characterization of an interleukin-2-like cytokine produced by Xenopus laevis T lymphocytes.
Developmental immunology 1993 Jan;3(3):231-8
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Transforming growth factor beta (TGF beta) is produced by and influences the proliferative response of Xenopus laevis lymphocytes.
Developmental immunology 1993 Jan;3(3):223-30
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Immune system activation associated with a naturally occurring infection in Xenopus laevis.
Developmental and comparative immunology 1992 Jan;16(6):453-62
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Shark spontaneous cytotoxicity: characterization of the regulatory cell.
Developmental and comparative immunology 1991 Jan;15(3):123-34
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A monoclonal antibody against the human IL-2 receptor binds to paraformaldehyde-fixed but not viable frog (Xenopus) splenocytes.
Immunology letters 1990 Dec;26(3):227-32
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Xenopus TCGF
Developmental And Comparative Immunology 1989 Jan;13(4):356
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Fc receptor for shark IgM.
Developmental and comparative immunology 1988 Jan;12(3):561-71
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Macrophage-like effector of spontaneous cytotoxicity from the shark.
Developmental and comparative immunology 1986 Jan;10(4):497-508
Book Chapters
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The Aging Immune System, Vaccine Efficacy, and the Lung
The Aging Lung: Mechanism and Clinical Sequela 2015 Jan;
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The Phylogentic Conservation of Cytokines
Phylogenesis of Immune Function 1991 Jan;241
Editorials
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Editorial: Horizons in aging, immune system and infectious diseases.
Frontiers in aging 2022 Jan;31034531
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Editorial: Insights in aging and the immune system: 2021.
Frontiers in aging 2022 Jan;3999299
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Editorial: Women in Aging Research.
Frontiers in aging 2022 Jan;3913488
Letters
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Natural immunity helps overcome the age-related decline of SARS-CoV-2 vaccine immunogenicity.
The Lancet. Healthy longevity 2022 Jul;3(7):e449-e450
Reviews
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Impact of senolytic treatment on immunity, aging, and disease.
Frontiers in aging 2023 Jan;41161799
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Influenza Vaccination in Older Adults: Recent Innovations and Practical Applications.
Drugs & aging 2018 Nov;3629-37
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The impact of aging on CD4+ T cell responses to influenza infection.
Biogerontology 2018 Apr;19437-446
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Immune senescence: Significance of the stromal microenvironment.
Clinical and experimental immunology 2016 Aug;1876-15
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T-Cell Immunity to Influenza in Older Adults: A Pathophysiological Framework for Development of More Effective Vaccines.
Frontiers in immunology 2016 Jan;741
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Vaccine strategies to enhance immune responses in the aged.
Current opinion in immunology 2013 Jun;25(4):523-8
| Title or Abstract | Type | Sponsor/Event | Date/Year | Location |
|---|---|---|---|---|
| Aging and Influenza: is senescence involved? | Talk | Division of Medicine, University College London, London, UK | 2023 | London, UK |
| Aging Response to Vaccination | Talk | Infectious Disease Week 2023 | 2023 | Boston, MA |
| Senescence-induced changes in CD4 T cell differentiation can be alleviated by treatment with senolytics | Talk | Jackson Lab"Systems Immunology in Aging and Complex Diseases" symposium | 2021 | Farmington, CT |
| The science behind COVID-19 vaccines: establishing clinical foundations & addressing common misconceptions | Talk | American Foundation for Aging Research | 2021 | Virtual |
| Aging and Influenza | Talk | Department of Nutritional Sciences, UConn Storrs | 2021 | |
| Aging and Influenza | Talk | University of Georgia | 2020 | Department of Infectious Diseases, University of GA, Athens, GA |
| Heterogeneity of Aging | Panel Discussion | 2020 | Gerontological Society of American Annual Meeting | |
| Aging and Immunity | Talk | University of Vermont College of Medicine | 2019 | Burlington, VT |
| The impact of aging on the response to influenza | Talk | Keystone: Aging, Inflammation and Immunity | 2018 | Austin, Texas |
| How aging impacts the response to influenza | Talk | British Society for Research on Aging | 2017 | Exeter, UK |
| How aging impacts the response to influenza infection | Talk | University of Iowa | 2017 | Iowa City, IA |
| Impact of aging on CD4 T cell response to influenza | Talk | Satellite Symposium of the 4th European Congress of Immunology | 2015 | Vienna, Austria |
| Aging and the response to influenza infection | Talk | Pasteur Institute | 2015 | Paris, France |
| Protective humoral immunity and Tfh function decline with age. | Talk | AAI | 2014 | AAI meeting, Pittsburgh, PA |
| Effect of age on immune responses. | Talk | Yale Biology of Aging Interest Group | 2014 | New Haven, CT |
| Vaccination with influenza NP does not protect aged mice | Talk | Harnessing Immunity Conference, Cold Spring Harbor, NY | 2013 | |
| Influence of Aging on CD4 T Cells | Talk | University of Rochester School of Medicine | 2011 | Rochester, New York |
| Innate Programming of Adaptive Immunity II The Impact of Aging on CD4 T Function | Talk | Cold Spring Harbor Symposium | 2011 | Cold Spring Harbor, New York |
| The Influence of Aging on CD4 T Cell Response to Vaccination | Talk | Aaron Diamond AIDS Research Center | 2010 | New York, New York |
| Presentation on Function of Regenerated CD4 T Cells | Talk | FASEB Summer Conference | 2010 | Phoenix, Arizona |
| Speaker | Talk | 9th Canadian Immunization Conference | 2010 | Quebec City, QC |
| The Influence of Aging on CD4 T Cell Response to Vaccination | Talk | George Washington University | 2009 | Washington, DC |
| The Influence of Aging on CD4 T Cell Response to Vaccination | Talk | University of Pittsburgh Medical School | 2009 | Pittsburgh, Pennsylvania |
| The Influence of Aging on CD4 T Cell Response to Vaccination | Talk | NIAID/ Department of Defense | 2008 | San Francisco, California |
| The Influence of Aging on CD4 T Cell Response to Vaccination | Talk | New York State Department of Health | 2008 | Albany, New York |
| The Effect of Aging on Primary & Memory Responses of CD4 T Cells | Talk | Aging & Memory at Keystone Symposium on Immunologic Memory | 2007 | Santa Fe, New Mexico |
| Networking and Mentoring: How to Make it For You | Talk | AAI Committee | 2007 | Miami, Florida |
| T Cell Defects With Aging | Talk | NIAID/NIA | 2007 | Gaithersburg, Maryland |
| T Cell Defects With Aging | Talk | Yale University School of Medicine, Immunobiology Seminar Series | 2007 | New Haven, Connecticut |
| Cytokine Adjuvants Enhance the Cognate Helper Function of Aged CD4 T Cells | Panel Discussion | International Congress of Immunology | 2007 | Rio de Janeiro, Brazil |
| The Effect of Aging on CD4 T Cell Responses | Talk | Iowa State University | 2007 | Ames, Iowa |
| Newly Generated CD4 T Cells in Aged Animals do not Exhibit Age-Related Defects in Response to Antigen | Talk | NIA/NIH National Advisory Council on Aging | 2006 | Bethesda, Maryland |
| The Effect of Age on CD4 T Cell Function | Talk | University of Iowa, Cancer and Aging Program | 2006 | Iowa City, Iowa |
| Enhancement of the Cognate Helper Activity of Aged CD4 T cells | Talk | National Institute on Aging: AAI Meeting | 2006 | Boston, Massachusetts |
| The effect of age on the cognate function of CD4 T cells | Lecture | American Aging Association | 2006 | Boston, Massachusetts |
| How Can Vaccines Work on the Background of the Aging Immune System? | Lecture | Aging Research in Immunology | 2006 | Paris, France |
| The Effect of Age on CD4 T Cell Memory | Lecture | Louisiana State University | 2005 | New Orleans, Louisiana |
| The Effect of Aging on Cognate CD4 Helper Function | Lecture | Edward Jenner Institute for Vaccine Research | 2005 | Compton, U.K. |
| The Effect of Age on the Function of CD4 T Cells | Lecture | German Cancer Research Center DKFZ | 2005 | Heidelberg, Germany |
| The Effect of Aging on Cognate CD4 Helper Function | Lecture | Yale University School of Medicine | 2005 | New Haven, Connecticut |
| The Effect of Age on the Function of CD4 T Cells | Lecture | La Jolla Institute of Molecular Medicine | 2005 | La Jolla, California |
| The Effect of Age on CD4 T Cell Memory | Talk | President's Symposium, AAI/EB Meeting | 2005 | San Diego, California |
| The Effect of Age on CD4 T Cell Function | Talk | Ohio State University | 2004 | Ohio |
| Age-Related Declines in CD4 Cognate Function are Responsible for Reduced Humoral Responses in the Aged | Talk | Lovelace Respiratory Research Institute Symposium | 2004 | Santa Fe, New Mexico |
| The Effect of Age on CD4 T Cell Function | Talk | Sidney Kimmel Cancer Center | 2003 | La Jolla, California |
| Impaired CD4 T Cell Cognate Function is Responisble for Age-Related Reductions in Humoral Responses | Talk | Upstate NY Immunology Conference | 2003 | Bolton Landing, New York |
| The Effect of Age on CD4 T Cell Function | Talk | University of Rochester School of Medicine | 2002 | Rochester, New York |