Photo of Upendra P. Hegde, M.D.

Upendra P. Hegde, M.D.

Professor of Medicine (in Residence)
Co-Director, Melanoma and Cutaneous Oncology Program
Co-Director, Head and Neck and Oral Oncology Program
Director, Oncology Inpatient Unit
Academic Office Location:
UConn Health
263 Farmington Avenue
Farmington, CT 06030
Phone: 800-579-7822
M.B.B.S.Goa Medical CollegeMedicine, Surgery
M.D.Goa Medical CollegeGeneral Medicine

Post-Graduate Training
ResidencyGoa Medical College and HospitalCompulsory Rotatory
ResidencyGoa Medical College and HospitalPsychiatry and Human Behavior
ResidencyGoa Medical College and HospitalInternal Medicine
ResidencyGoa Medical College and HospitalInternal Medicine
FellowshipTata Memorial Cancer HospitalHematology/Oncology
FellowshipTata Memorial HospitalHematology/Oncology
Research ScholarRush University Cancer Institute
ResidencyCook County HospitalInternal Medicine
FellowshipNational Heart, Lung, and Blood InstituteHematology and Medical Oncology

Name of Award/HonorAwarding Organization
Ranked amongst most highly by the Internal Medicine residents over the past academic yearDepartment of Medicine
America's Top DoctorsCastle Connolly's
Top Doctor in Connecticut Magazine 2017Connectictut Magazine
Leonard Tow 2016 Humanism in Medicine AwardThe Arnold P. Gold Foundation
America’s Best DoctorU.S. Public News
Named Top Doctor, Connecticut Magazine Survey of Connecticut Doctors Connecticut Magazine
Best Teaching Award, Hematology/Oncology Training Program, 2008-2009 UConn Health Center
PAWS Team Award, UConn Health CenterUConn Health Center Cares Council
Recipient of Scholarship Towards ASCO/AACR Workshop
Humanitarian Resident AwardCook County Hospital
Humanitarian Resident Award, Chicago, Illinois, 1996-1997 Cook County Hospital
USMLE 1, 2, 3
J.N. Tata Endowment Travel Scholarship
Research Scholarship, Chicago, Illinois, 1992-1995 Rush University Cancer Institute
Khandelwal Junior Oncology Award, Madras, India Indian Society of Oncology
Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
Institutional Review BoardOtherCo-Chair, Panel 2UConn HealthUniversity2016
Institutional Review BoardProfessional/Scientific OrganizationCo-Chairman Panel 2UConn HealthUniversity2014
Quality and Resource ManagementAdvisory CommitteeMemberUConn HealthLocal20142018
Search Committee for Faculty RecruitmentEducation CommitteeCommittee MemberUConn HealthUniversity2009
Schwartz Round Planning and Patient Selection CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity2009
Scientific Review Committee for the Institutional American Cancer Society Research AwardProfessional/Scientific OrganizationMemberUConn HealthUniversity2009
Search Committee for Medical Oncology/Hematology Faculty RecruitmentProfessional/Scientific OrganizationMemberUConn HealthUniversity2009
Search Committee for Gynecologic Oncology Faculty RecruitmentProfessional/Scientific OrganizationQuality Assurance LiaisonUConn HealthUniversity2009
American Association for Cancer ResearchProfessional/Scientific OrganizationMemberExternalNational2005
Connecticut State Society of Medical OncologyProfessional/Scientific OrganizationMemberExternalState2003
Cancer Registry and Quality Control CommitteeAdvisory CommitteeMemberUConn HealthUniversity2003
American Society of Clinical OncologyProfessional/Scientific OrganizationMemberExternalNational2000
American Society of HematologyProfessional/Scientific OrganizationMemberExternalNational19982003
Department of Medicine Q/A committeeProfessional/Scientific OrganizationLiaisonUConn HealthUniversity

Journal Articles

Book Chapters

  • Skin Cancers and Melanoma
    Hegde UP, Agarwala SS The Bethesda Handbook of Clinical Oncology 2018 Jun;
  • Skin Cancers and Melanoma: Review questions
    Hegde UP, Agarwala SS The Bethesda Review of Clinical Oncology 2018 Jun;205-220


  • Influence of age and cancer history on prevalence of autoimmunity in patients with metastatic melanoma: A large retrospective study
    Holmes A*, Wang X, Swede H, Hegde U. Journal of Clinical Oncology. 38,2020. Proceedings of the 56th Annual Meeting of the American Society of Clinical Oncology 2020. 2020 May;38
  • Autoimmune toxicities with anti-PD-1 treatment of metastatic melanoma in predominantly older patients: A single institutional experience.
    Harsh V Parmar, Phil Kerr, Christina Elizabeth Stevenson, Sophie Masternak, and Upendra P. Hegde Journal of Clinical Oncology 2019 Mar;37(8):144
  • Clinical heterogeneity of elderly melanoma patients in the real-world setting: Potential implications for treatment outcomes following immune based therapy
    Upendra P. Hegde, Harsh V Parmar, Christina Elizabeth Stevenson Journal of Clinical Oncology 2019 Mar;37(15):e21026
  • Peripheral blood T-cell functional assay as a predictive biomarker of immune-therapy of metastatic melanoma.
    Parmar H, Chakraborty N, Hegde UP* Journal of Clinical Oncology 2018 Jun;36(Suppl abstr e21593):
  • Determination of the potential of detecting 3q gain as a valuable biomarker in the management of patients with human papilloma virus (HPV) associated oropharyngeal squamous cell carcinoma (OPSCC)
    Hegde UP, Kershnar E, Dowsett R, Masternak S, Verma Y, Triantafyllos ASCO Annueal Meeting 2017 (suppl:abstr e17534)
  • Immune checkpoint inhibitor treatment of advanced age metastatic melanoma (MM patients.
    Hegde UP, KerrP, Masternak S, Brenner BM, Grant-Kels J ASCO Annual Meeting Abstracts 2017 (suppl;abstr e14603)
  • Outcome of metastatic melanoma following immune checkpoint inhibitor treatment by tumor infiltrating lymphocytes of primary cutaneous site
    Hegde U*, Holmes A, Cucka B, Masternak S, Stevenson C Journal of Clinical Oncology. (Suppl; e22005). 2020.(Suppl: e22005):
  • Outcome of metastatic melanoma following immune checkpoint inhibitor treatment by tumor infiltrating lymphocytes of primary cutaneous site
    Hegde U*, Holmes A, Cucka B, Masternak S, Stevenson C. Journal of Clinical Oncology. (Suppl; e22005).Proceeding of the 56 annual meeting of the American Society of Clinical Oncology 2020 38
  • Quite breaking my heart; 5-Fluorouracil Associated Cardiomyopathy Presented by the first author at the national meeting of the Society of Internal Medicine in Washington 2017
    Zawadzka S, Hegde UP National Meeting of the Society of Internal Medicine in Washington 2017

Case Reports

  • Multiple autoimmune side effects of immune checkpoint inhibitors in a patient with metastatic melanoma receiving Pembrolizumab
    Kethireddy N, Thomas S, Bindal P, Shukla P, Hegde U*. Journal of Oncology Pharmacy Practice 2020 May;27(1):207-211
  • Bilateral spontaneous subdural hematomas as the initial presentation of von Willebrand Disease: A case report and review of the literature
    Van den Bergh M, Panwala A, Khanapara D, Hegde UP

Conference Papers


  • Peripheral blood T-cell functional assay as a predictive biomarker of immune-therapy of metastatic melanoma
Title or AbstractTypeSponsor/EventDate/YearLocation
Immunotherapy of cancer: melanoma as a tumor model. Medical Resident Didactic noon talk via WebexLecture2020October 26, University of Connecticut
Metastatic melanoma in the elderly Clinical observations and Immunologic insightsTalkVA2018VA, West Haven, CT
Metastatic melanoma in the aging population: clinical and immunologic insightsTalkNational Cancer Center, National Institutes of Heallth2018Bethesda, MD
Metastatic melanoma in the elderly: T cell checkpoint blockade and toxicity - does age matter?TalkDepartment of Immunology2018UCONN, Department of Immunology
Peripherally induced Tregs or pTregs are the potent tolerance inducer for the growth and metastasis of cancerPosterAmerican Association of Cancer Research, Annual Meeting, Chicago, IL 20182018Chicago, IL
Case Conference 1/6/17LectureUConn2017UConn
Case Conference 4/7/17LectureUConn2017UConn
Case Conference 7/7/17LectureUConn2017UConn
Case Conference 10/6/17LectureUConn2017UConn