Photo of John Travis Hinson, M.D.

John Travis Hinson, M.D.

Associate Professor of Cardiology and Genetics
NPI Number:
Academic Office Location:
Pat and Jim Calhoun Cardiology Center
UConn Health
263 Farmington Avenue
Farmington, CT 06030
Phone: 860-679-3343

Pat and Jim Calhoun Cardiology Center

Genetics and Developmental Biology Graduate Program

Hinson Lab Page

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Dr. Travis Hinson is the second joint faculty appointment with The Jackson Laboratory for Genomic Medicine. He brings his expertise in cardiovascular genetics from Brigham and Women’s Hospital. Dr. Hinson’s study of the genetics of heart muscle diseases includes the bioengineering of heart cells derived from pluripotent stem cells. He also treats patients with inherited forms of cardiovascular diseases.

M.D.Havard Medical SchoolMedicine

Post-Graduate Training
ResidencyMassachusetts General HospitalInternal Medicine
FellowshipBrigham and Women's HospitalCardiovascular Medicine

Cardiovascular genetics

My laboratory utilizes genomic approaches to interrogate mechanisms of inherited cardiovascular disorders especially those that lead to heart failure. We are particularly interested in developing single cell and cardiac microtissue assays derived from disease-specific, human induced pluripotent stem cells (iPScs) in combination with in vivo mouse models. My lab’s current research focus is directed toward: 1) defining the role of AMPactivated protein kinase in physiologic and pathologic forms of cardiac remodeling; 2) engineering cardiac microtissues to study the most common forms of familial hypertrophic and dilated cardiomyopathies due to sarcomere mutations; and 3) to develop assays for high-throughput functional genomic screens to predict pathogenicity of genetic variation in cardiomyopathy genes. These studies capitalize on the laboratory’s expertise in human genetics, stem cell biology, tissue engineering and computational methods.

Accepting Lab Rotation Students: Summer 2022, Fall 2022, and Spring 2023

Journal Articles

Case Reports



  • Molecular genetic mechanisms of dilated cardiomyopathy.
    Hinson, John Travis Current opinion in genetics & development 2022 Jul;76101959
  • The Cardiac Sarcomere and Cell Cycle.
    Pettinato, Anthony M; Ladha, Feria A; Hinson, J Travis Current cardiology reports 2022 Apr;
  • The NIH Somatic Cell Genome Editing program.
    Saha, Krishanu; Sontheimer, Erik J; Brooks, P J; Dwinell, Melinda R; Gersbach, Charles A; Liu, David R; Murray, Stephen A; Tsai, Shengdar Q; Wilson, Ross C; Anderson, Daniel G; Asokan, Aravind; Banfield, Jillian F; Bankiewicz, Krystof S; Bao, Gang; Bulte, Jeff W M; Bursac, Nenad; Campbell, Jarryd M; Carlson, Daniel F; Chaikof, Elliot L; Chen, Zheng-Yi; Cheng, R Holland; Clark, Karl J; Curiel, David T; Dahlman, James E; Deverman, Benjamin E; Dickinson, Mary E; Doudna, Jennifer A; Ekker, Stephen C; Emborg, Marina E; Feng, Guoping; Freedman, Benjamin S; Gamm, David M; Gao, Guangping; Ghiran, Ionita C; Glazer, Peter M; Gong, Shaoqin; Heaney, Jason D; Hennebold, Jon D; Hinson, John T; Khvorova, Anastasia; Kiani, Samira; Lagor, William R; Lam, Kit S; Leong, Kam W; Levine, Jon E; Lewis, Jennifer A; Lutz, Cathleen M; Ly, Danith H; Maragh, Samantha; McCray, Paul B; McDevitt, Todd C; Mirochnitchenko, Oleg; Morizane, Ryuji; Murthy, Niren; Prather, Randall S; Ronald, John A; Roy, Subhojit; Roy, Sushmita; Sabbisetti, Venkata; Saltzman, W Mark; Santangelo, Philip J; Segal, David J; Shimoyama, Mary; Skala, Melissa C; Tarantal, Alice F; Tilton, John C; Truskey, George A; Vandsburger, Moriel; Watts, Jonathan K; Wells, Kevin D; Wolfe, Scot A; Xu, Qiaobing; Xue, Wen; Yi, Guohua; Zhou, Jiangbing; SCGE Consortium Nature 2021 Apr;592(7853):195-204