Photo of Marja  Hurley, M.D.

Marja Hurley, M.D.

Professor of Medicine and Orthopedic Surgery
Academic Office Location:
Medicine
UConn Health
263 Farmington Avenue
Farmington, CT 06030-1850
Phone: 860-679-2129
Fax: 860-679-2158
Website(s):

Hurley Lab

Cell Biology Graduate Program

Skeletal Biology and Regeneration Graduate Program

General Overview:  Dr. Marja Hurley is Professor of Medicine and Orthopedics and Member of the Institute of Systems Genomics at the University of Connecticut School of Medicine. She is the first woman of color to receive the doctor of medicine from UConn School of Medicine and the first to be a tenured full professor at the UConn Health School of Medicine. Dr. Hurley has made outstanding contributions as an administrator, educator and physician research scientist at UCONN Health and received local, national and international recognition and awards for her accomplishments in several of these domains. These include elected as a Fellow of the American Society for Bone and Mineral Research in 2018; Recipient of the 2018 University of Connecticut School of Medicine Distinguished Alumni Award; recipient of the prestigious 2016 Lawrence G Raisz Esteemed Award from the American Society for Bone Mineral Research for preclinical translational research; induction into the Connecticut Academy of Science and Engineering in 2012 and the 2011 UConn Health Board of Directors Faculty Recognition Award and the Neag Medal of Honor. She also received the University of Connecticut first Martin Luther King Award for Achievement in Science and was recognized as one of the outstanding women in 100 years at the University of Connecticut. In 2010, she was the winner of the Connecticut Technology Council Women of Innovation and Leadership Award. Dr Hurley also serves as liaison to the AAMC Group on Women in Medicine and Science. In recognition of her contributions to educational diversity, Dr. Hurley has received numerous awards including the first New England Board of Higher Education Award for innovation and excellence in higher education in 2003; the West Indian Foundation Community Service Award; the Community Service Award from the Capital Area Health Consortium and the Distinguished Service Award from the Foundation for Educational Achievement at Central Connecticut State University. She was also appointed Commissioner and served on the Connecticut Legislative Commission on Health Equity.

Education Diversity Initiatives:  Dr. Hurley has made significant contributions in medical education diversity as Associate Dean and Director of the Health Career Opportunity Program for more than 25 years.  During this time, she has fostered the enrollment and career development of students in biomedical science at every level of the pipeline and substantially increased the number of underrepresented and first generation students attending the UConn Schools of Medicine and Dental Medicine. Dr. Hurley is the Founding Director of the Aetna Health Professions Partnership Initiative at UConn Health that now consists of 14 distinct programs for which Dr. Hurley secured more than $14 million in extramural grants. These programs were endowed as The Aetna Health Professions Partnership Initiative with a 2-million-dollar gift from the Aetna Foundation. The success of this initiative can be assessed by the more than 600 students who have been successful in gaining acceptance to U.S. Health Professions and Graduate Schools. Dr. Hurley is recognized nationally as a leader in education equity and has been appointed to several key committees in education both in medicine and dentistry at the local and national levels, and has been an invited speaker at national meetings sponsored by the National Academy of Sciences, the Association of American Medical Colleges, the American Dental Education Association, the Kellogg and Robert Wood Johnson Foundations, and more. She  served as Chair of the Women’s Affairs Committee of the American Dental Education Association and was an invited speaker/panelist at the Sullivan Alliance National Leadership Symposium on Health Professions Diversity. She was invited to present by The  CT Governor’s Office for Workforce Development on the UConn Health Professions Partnership Initiative as a successful model of Connecticut Career Choices. She was appointed to the Connecticut State Department of Education and the Department of Higher Education College Ready Advisory Sub-Committee of the Higher Education PK-16 Council. She was an invited panelist at the 2008, 2012 and 2014 Harvard Medical School, Biomedical Science Careers Student Conferences. Dr. Hurley was recently named Chair Elect of the Oversight Committee of NIH, NIDDK Network of Minority Health Research Investigators.

Administration:  Dr. Hurley  serves as the Associate Dean for the Health Career Opportunity Programs at UConn Health. Dr. Hurley’s commitment to education of UCONN medical students is exemplified by her willingness in 2010-2011 to serve as Interim Senior Associate Dean for Education and Academic Affairs. During this period, she played a key role in establishing new UConn School of Medicine governance for medical student education as well as the development and implementation of the LCME action plan for reaccreditation of the School of Medicine. She served as Chair of the Education Council, Chair of the Committee on Undergraduate Medical Education (CUME) and Liaison to the Academic Affairs Committee of the Board of Directors of UConn Health. In recognition of her outstanding administrative leadership, she has served on major leadership committees at UConn Health, including the Vice President’s Advisory Committee; Chancellors Advisory Committee; Senior Appointments and Promotion Committee, Senior Administrative Group and Special Assistant to the Dean School of Medicine. Dr. Hurley currently serves as a voting member of the Academic Affairs Sub Committee of the UCONN Health Board of Directors, the Dean's Council and the Education Council.

Education
DegreeInstitutionMajor
B.A.University of ConnecticutBiology
M.D.University of Connecticut Health CenterMedicine

Post-Graduate Training
TrainingInstitutionSpecialty
ResidencyUniversity of Connecticut Health CenterInternal Medicine
FellowshipUniversity of Connecticut Health CenterEndocrinology

Awards
Name of Award/HonorAwarding Organization
Alumni Distinguished Faculty Award, UCONN School of MedicineUCONN School of Medicine
Chair 2018 Fibroblast Growth Factors in Development and Disease Gordon Research ConferenceGordon Research Conference
Elected Vice Chair FGF Gordon Research Conference, Hong Kong, China, 2016FGF Gordon Research Conference, Hong Kong, China,
American Society of Bone and Mineral Research Lawrence G. Raisz, Esteemed Award for outstanding achievement in preclinical translational researchAmerican Society of Bone and Mineral Research
Spotlight SpeakerOrthopedic Research Society, Annual Meeting, March 2014Orthopedic Research Society
Elected Chairman American Dental Education Association Women’s Affairs Advisory Committee
Elected as a Member of the Connecticut Academy of Science and EngineeringConnecticut Academy of Science and Engineering
Recipient of the Greater Hartford West Indian Lions Club Community Service AwardGreater Hartford West Indian Lions Club
University of Connecticut Health Center Board of Directors Faculty Recognition AwardUniversity of Connecticut School of Medicine
Recipient Neag Medal of HonorUniversity of Connecticut Health Center
Faculty HonoreeUniversity of Connecticut Health Center, White Coat GALA
Winner Connecticut Science and Technology Woman of Innovation and Leadership AwardConnecticut Science and Technology Council
Recipient of the West Indian Foundation Outstanding Community Service AwardWest Indian Foundation
New England Higher Education Excellence Award for Innovation in EducationNew England Board of Higher Education
Distinguished Service Award; Foundation for Education AdvancementCentral Connecticut State University
Community Service AwardCapital Area Health Consortium
Nominated by the Chancellor and Selected for Participation in Summer Institute for Women in Higher EducationBryn Mawr College
Award Winner, 100 Years of Women at the University of ConnecticutUniversity of Connecticut
Martin Luther King Award for Achievement in ScienceUniversity of Connecticut
National Research Service Award, National Institutes of HealthNIH
HonoreeUniversity of Connecticut
Recipient NIH Endocrine Student FellowshipNational Institute of Health
Mosby Publishing Award for Excellence in Clinical MedicineUniversity of Connecticut School of Medicine

Clinical Case Conference Leader; Organ Systems 3 course for UCHC first year medical and dental students;Clinical Case Conference Leader; Disorders of bone and mineral metabolism course for UCHC second year medical and dental students. I supervise graduate students in the Skeletal Oral Biology area of concentration.

Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
Fibroblast Growth Factor in Development and Disease GORDON Research ConferenceProfessional/Scientific OrganizationChairExternalInternational20172018
Elected Member Publications Committee, American Society for Bone and Mineral ResearchProfessional/Scientific OrganizationMemberExternalNational20172020
American Society of Bone and Mineral Research 2018 Annual Meeting Planning CommitteeProfessional/Scientific OrganizationChair, Translational ProgramExternalInternational20172018
NIDDK, Network of Minority Health Research Investigators.Advisory CommitteeMemberExternalNational20162019
Elected Member of the Women in Bone and Mineral Research Committee of ASBMRProfessional/Scientific OrganizationElected MemberExternalNational20142017
Connecticut Academy of Science and EngineeringProfessional/Scientific OrganizationMemberExternalState2012
American Federation for Medical ResearchProfessional/Scientific OrganizationMemberExternalNational2012
American Dental Education Association: Affairs Advisory CommitteeAdvisory CommitteeMemberExternalNational2012
European Calcified Tissue Society: Review Panel for the 2011-2012 Grants and AwardsProfessional/Scientific OrganizationMemberExternalInternational20112012
GeneEditorial BoardAssociate EditorExternalNational20112013
University of Connecticut Health Center: Search Committee, Director MD/PhD ProgramProfessional/Scientific OrganizationMemberUConn HealthUniversity20112011
American Society for Bone and Mineral Research: Scientific Program CommitteeProfessional/Scientific OrganizationMemberExternalNational20102010
University of Connecticut Health Center: LCME Action Plan CommitteeEducation CommitteeMemberUConn HealthUniversity20102012
University of Connecticut Health Center: Search Committee Senior Associate Dean of Education, School of MedicineProfessional/Scientific OrganizationMemberUConn HealthUniversity20102011
University of Connecticut Health Center: Search Committee Assistant Dean, School of MedicineProfessional/Scientific OrganizationMemberUConn HealthUniversity20102010
University of Connecticut Health Center: Search Committee, Student Services DirectorProfessional/Scientific OrganizationMemberUConn HealthUniversity20102010
ASBMR: Membership Development CommitteeProfessional/Scientific OrganizationMemberExternalNational20092012
University of Connecticut Health Center: Representative to the Association of American Medical Colleges Group on Women in Medicine and Science (GWIMS)Professional/Scientific OrganizationRepresentativeUConn HealthUniversity2009
University of Connecticut Health Center: DMD/MPH Advisory Committee School of Dental MedicineAdvisory CommitteeMemberUConn HealthUniversity20092014
University of Connecticut Health Center: UCONN/COBB/NMA Planning CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity20092011
University of Connecticut Health Center: School of Medicine Academic Plan Development CommitteeProfessional/Scientific OrganizationCo-leaderUConn HealthUniversity20092009
University of Connecticut Health Center: Employee Philanthropy CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity20092010
Association of American Medical Colleges Group on Women in Medicine and ScienceProfessional/Scientific OrganizationRepresentativeExternalNational2009
State of Connecticut Legislative Commission on Health EquityProfessional/Scientific OrganizationCommissionerExternalState2009
The Science Engineering & Health Professions Collaborative SymposiumWorkshop/ConferenceLeaderUConn HealthUniversity20092009
New York Academy of SciencesProfessional/Scientific OrganizationMemberExternalState2008
NIH: Skeletal Biology Development and Disease Study SectionProfessional/Scientific OrganizationMemberExternalNational20082012
University of Connecticut Health Center: LCME Institutional Self-Study CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity20082010
University of Connecticut Health Center: Clinical and Translational Research Training Grant Planning CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity20082010
Biomedical Science Careers Student Conference: Harvard Medical SchoolWorkshop/ConferencePanelistExternalUniversity20082008
American Society for Bone and Mineral Research: Bone and CartilageProfessional/Scientific OrganizationSession Co-ChairExternalNational20072007
University of Connecticut Health Center: Institutional Self-Study CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity20072008
University of Connecticut Health Center: Search Committee, Vice President/Dean School of MedicineProfessional/Scientific OrganizationMemberUConn HealthUniversity20072008
Connecticut State Department of Education and the Department of Higher Education College Ready Advisory Sub-Committee of the Higher Education PK-16 CouncilProfessional/Scientific OrganizationMemberExternalUniversity2007
American Society for Bone and Mineral Research: Scientific Program CommitteeProfessional/Scientific OrganizationMemberExternalNational20062006
NIH Study Section: Special Emphasis Panel/Scientific Review GroupProfessional/Scientific OrganizationMemberExternalNational2006
University of Connecticut Health Center: MD/PhD Steering CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity2006
University of Connecticut Health Center: Senior Appointments and Promotions CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity20062009
University of Connecticut Health Center: Search Committee, Dean, School of NursingProfessional/Scientific OrganizationMemberUConn HealthUniversity20062006
American Dental Education Association: Advisory CommitteeProfessional/Scientific OrganizationChairmanExternalNational20062006
American Dental Education Association Institutes for Policy and Advocacy: Minority Affairs CommitteeProfessional/Scientific OrganizationChairExternalNational20062006
Seventh Annual Diversity and Access to Dental Careers conferenceWorkshop/ConferenceOpening Session ModeratorExternalNational20062006
American Society for Bone and Mineral Research: Peptide Calciotropic HormonesProfessional/Scientific OrganizationSession Co-ChairExternalNational20052005
Endocrine Society: Steering CommitteeProfessional/Scientific OrganizationMemberExternalNational20052008
Endocrine Society: Basic Insights into OsteoporosisProfessional/Scientific OrganizationChairmanExternalNational20052005
Association of American Medical Colleges: Building Diversity in Medicine Working GroupProfessional/Scientific OrganizationMemberExternalNational20052005
University of Connecticut: Skeletal Craniofacial and Oral Biology Research SymposiumProfessional/Scientific OrganizationSession ChairUConn HealthUniversity20042004
American Society for Bone and Mineral Research: Scientific Program CommitteeProfessional/Scientific OrganizationMemberExternalNational20042004
MAS, Advisory Committee of the American Dental Education AssociationAdvisory CommitteeMemberExternalNational20042007
UCONN Center for Public Health and Health Policy: Advisory BoardAdvisory CommitteeMemberUConn HealthUniversity20042004
BoneProfessional/Scientific JournalMemberExternalNational2003
Cell and Tissue ResearchProfessional/Scientific JournalMemberExternalNational2003
Developmental BiologyProfessional/Scientific JournalMemberExternalNational2003
EndocrinologyProfessional/Scientific JournalMemberExternalNational2003
GeneProfessional/Scientific JournalMemberExternalNational2003
Inflammatory Bowel DiseasesProfessional/Scientific JournalMemberExternalNational2003
Journal Bone and Mineral ResearchProfessional/Scientific JournalMemberExternalNational2003
Journal Clinical Orthopaedic and Related ResearchProfessional/Scientific JournalMemberExternalNational2003
Journal Cell ScienceProfessional/Scientific JournalMemberExternalNational2003
Osteoporosis InternationalProfessional/Scientific JournalMemberExternalNational2003
American Society for Bone and Mineral Research: Scientific Program CommitteeProfessional/Scientific OrganizationMemberExternalNational20022002
International Bone and Mineral SocietyProfessional/Scientific OrganizationMemberExternalInternational2001
American Society for Bone and Mineral Research: Education CommitteeProfessional/Scientific OrganizationMemberExternalNational20012004
American Society for Bone and Mineral Research: Scientific Program CommitteeProfessional/Scientific OrganizationMemberExternalNational20012001
NIH: Orthopedic and Musculoskeletal Study SectionProfessional/Scientific OrganizationMemberExternalNational20002004
University of Connecticut Health Center: Graduate Program Ph.D. Strategic Planning CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity20002000
American Society for Bone and Mineral Research: BMP’s, TGF-Beta and Other Growth FactorsProfessional/Scientific OrganizationCo-Chair Scientific SessionExternalNational19991999
University of Connecticut Health Center: Graduate Programs CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity1999
American Society for Bone and Mineral Research-International Bone and Mineral Society: Scientific Program CommitteeProfessional/Scientific OrganizationMemberExternalNational19981998
American Society for Bone and Mineral Research: BMP’s, TGF-Beta and Other Growth FactorsProfessional/Scientific OrganizationCo-Chair Scientific SessionExternalNational19971997
University of Connecticut Health Center: Chancellor’s Advisory CommitteeAdvisory CommitteeMemberUConn HealthUniversity19961999
Connecticut State Medical SocietyProfessional/Scientific OrganizationMemberExternalState1995
The American Society for Cell BiologyProfessional/Scientific OrganizationMemberExternalNational1994
University of Connecticut Health Center: Institutional Accreditation Self-Study CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity19941995
NIH: Comparative Medicine Review Committee NCRRProfessional/Scientific OrganizationStudy Section MemberExternalNational19931997
University of Connecticut Health Center: Admissions Committee –College Student Summer ProgramsEducation CommitteeCo -ChairpersonUConn HealthUniversity1992
University of Connecticut Health Center: Vice President’s Advisory CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity19921996
University of Connecticut Health Center: Search Committee Dean School of MedicineProfessional/Scientific OrganizationMemberUConn HealthUniversity19921993
University of Connecticut Health Center: Search Committee, Vice President and Provost for Health AffairsProfessional/Scientific OrganizationMemberUConn HealthUniversity19921993
University of Connecticut Health Center: Institutional Self-Study CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity19921993
University of Connecticut Health Center: MD/PhD. Combined Degree Steering CommitteeEducation CommitteeMemberUConn HealthUniversity19921992
National Association of Advisors to the Health ProfessionProfessional/Scientific OrganizationMemberExternalNational1991
The Endocrine SocietyProfessional/Scientific OrganizationMemberExternalNational1991
Science Museum of Connecticut: Board of TrusteesProfessional/Scientific OrganizationMemberExternalState19911997
National Medical AssociationProfessional/Scientific OrganizationMemberExternalNational1990
University of Connecticut Health Center: Selection Committee High School Science Teacher Research ProgramProfessional/Scientific OrganizationChairpersonUConn HealthUniversity1990
University of Connecticut Health Center: Search CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity19901990
State of Connecticut Department of Higher Education: Peer Review CommitteeProfessional/Scientific OrganizationMemberExternalState19901994
Association of American Medical Colleges: Focus Group on “The Selection Process of Underrepresented Students in Medical Schools”Professional/Scientific OrganizationMemberExternalNational19901990
American Lung Association of Connecticut: Research and Grants CommitteeProfessional/Scientific OrganizationMemberExternalNational19891991
University of Connecticut Health Center: Commencement CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity1989
University of Connecticut Health Center: Board of Directors, Parent’s Association, School of MedicineProfessional/Scientific OrganizationMemberUConn HealthUniversity19891992
University of Connecticut Health Center: Introduction to Clinical Medicine CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity19891989
West Indian Foundation: Board of DirectorsProfessional/Scientific OrganizationMemberExternalState19891991
American Lung Association of Connecticut: Board of DirectorsProfessional/Scientific OrganizationMemberExternalState19891991
University of Connecticut School of Nursing Recruitment and Retention Campaign: Task Force-Executive Planning GroupProfessional/Scientific OrganizationMemberUConn HealthUniversity19891989
University of Connecticut Health Center: Search Committee Assistant Dean, Minority Student AffairsProfessional/Scientific OrganizationChairpersonUConn HealthUniversity19881988
American Society for Bone and Mineral ResearchProfessional/Scientific OrganizationMemberExternalNational1987
University of Connecticut Health Center: School of Medicine Institutional Self-Study Task ForceProfessional/Scientific OrganizationMemberUConn HealthUniversity19871988
University of Connecticut Health Center: Search Committee Assistant Dean, Dental Student AffairsProfessional/Scientific OrganizationMemberUConn HealthUniversity19871987
University of Connecticut Health Center: Promotions Committee-School of MedicineProfessional/Scientific OrganizationMemberUConn HealthUniversity1986
University of Connecticut Health Center: Predoctoral Admissions Committee-School of MedicineProfessional/Scientific OrganizationMemberUConn HealthUniversity1986
University of Connecticut Health Center: Medical Student Evaluation and Appeals CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity1986
University of Connecticut Health Center: Academic Performance Committees, I & II School of Dental MedicineProfessional/Scientific OrganizationMemberUConn HealthUniversity1986
University of Connecticut Health Center: School of Dental Medicine Predoctoral Admissions CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity1986
University of Connecticut Health Center: Elbert Powell Seminar SeriesProfessional/Scientific OrganizationChairpersonUConn HealthUniversity1986
University of Connecticut Health Center: Associate Dean and Director Health Career Opportunity ProgramsProfessional/Scientific OrganizationMemberUConn HealthUniversity1986
University of Connecticut Health Center: Medical Deans Advisory CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity19862006
University of Connecticut Health Center: Admissions Committee Minority Student Summer ProgramsEducation CommitteeChairpersonUConn HealthUniversity19861992
University of Connecticut Health Center: Affirmative Action CommitteeProfessional/Scientific OrganizationMemberUConn HealthUniversity19861987
Connecticut Endocrine SocietyProfessional/Scientific OrganizationMemberExternalState1984
University of Connecticut Health Center: Search Committee Dean, School of MedicineProfessional/Scientific OrganizationMemberUConn HealthUniversity19841984
Catholic Family Services Advisory BoardAdvisory CommitteeMemberExternalState19821983
Connecticut State Medical SocietyProfessional/Scientific OrganizationMemberExternalState19811981
American Medical Women’s AssociationProfessional/Scientific OrganizationMemberExternalNational19811981
Hartford County Medical AssociationProfessional/Scientific OrganizationMemberExternalLocal19811981
American Medical AssociationProfessional/Scientific OrganizationMemberExternalNational19761991
University of Connecticut Health Center: Committee on Women and MinoritiesProfessional/Scientific OrganizationMemberUConn HealthUniversity19761976
Connecticut Women’s Career CouncilProfessional/Scientific OrganizationMemberExternalState19741974
Student National Medical AssociationProfessional/Scientific OrganizationMemberExternalNational19721972
University of Connecticut Health Center; Admissions Committee, School of MedicineEducation CommitteeMemberUConn HealthUniversity19721972
Student National Medical Association MeetingProfessional/Scientific OrganizationRepresentativeExternalNational19721972
University of Connecticut Health Center: Minority and Women’s Day, Career OpportunitiesProfessional/Scientific OrganizationOrganizerUConn HealthUniversity19721972

Dr. Hurley is a physician scientist who is recognized nationally and internationally for her expertise on the role of fibroblast growth factor-2 (FGF2) in bone. She has supervised and mentored more than fifty students in research including women and underrepresented students many of whom have gone on to outstanding careers in academic medicine, dental medicine or biomedical research. Dr. Hurley’s research laboratory has made seminal observations on the importance of FGF2 in maintaining bone mass in mice as demonstrated by her publication in the premier Journal of Clinical Investigation. She has also co-authored papers in the Proceedings of the National Academy of Sciences and Nature Genetics. Dr. Hurley’s lab was the first to demonstrate that FGF2 expression in bone cells is increased by parathyroid hormone (PTH); the first anabolic agent approved by the FDA for osteoporosis treatment in the USA. Recently, Dr. Hurley’s lab demonstrated a novel role for the nuclear isoforms of FGF2 in phosphate homeostasis and was awarded a grant from NIDDK to study the potential role of these isoforms in human disorder X-Linked Hypophosphatemic Rickets. Dr. Hurley’s outstanding research productivity is demonstrated by her 162 peer reviewed publications as well as NIH research funding since 1989. Dr. Hurley has held leadership positions and has been an invited speaker at International Gordon Conferences, European Calcified Tissue Society, International Bone and Mineral Society, Endocrine Society, the American Society of Bone and Mineral Research (ASBMR) and the Orthopedic Research Society. She was elected Vice Chairman for the 2016 Gordon Conferences on Fibroblast Growth Factors in Development and Disease. Dr. Hurley has been highly sought to serve on NIH Scientific Review Panels and has served as a permanent member of several NIH Institutes. She serves as a reviewer of research proposals for the National Science Foundation and as a reviewer for several scientific journals in the field of bone research. She also serves as a reviewer of scientific articles for several specialty journals and served on the Editorial Board of Gene and currently serves on the Editorial Board of the Journal of Racial and Ethnic Health Disparities. Dr. Hurley is dedicated to the training and mentoring of the next generation of biomedical scientists. She is a member of the UConn graduate faculty for the Skeletal Biology and Regeneration and the Cell Biology areas of concentration in the Biomedical Sciences. Dr. Hurley was elected Chair of the prestigious international 2018 Gordon Conferences on Fibroblast Growth Factors in Development and Disease.

Accepting Lab Rotation Students: Fall '19, Spring '20


Lab Rotation Projects Areas of interest; Molecular mechanisms by which members of the fibroblast growth factor (FGFs) and fibroblast growth factor receptor (FGFR) families, (produced by osteoblasts, osteoclasts and stromal cells) regulate bone development, remodeling and disorders of bone. Project 1- Fgf2 knockout and Fgf2 transgenic mice are utilized in loss and gain of function experiments to elucidate the role of FGF-2 in disorders of bone including osteoporosis. Project 2- Examination of the effects of cytokines and hormones including interleukin-1 (IL-1), parathyroid hormone (PTH), insulin-like growth factor-I (IGF-I), transforming growth factor beta (TGF?), prostaglandins (PGs) and glucocorticoids on FGF2 and FGFR signaling, gene transcription, mRNA stability and the activity of transfected Fgf2 promoter-luciferase reporter gene constructs.

Journal Articles

Book Chapters

  • Fibroblast Growth Factor and Fibroblast Growth Factor Receptor Families in Bone
    Hurley, M.M., Marie, P.J., Florkiewicz, R. Principles of Bone Biology 825-851
  • Fibroblast Growth Factor and Fibroblast Growth Factor Receptor Families in Bone
    Hurley, M.M., Naski, M., Marie, P.J. Principles of Bone Biology 1103-1132
  • Fibroblast Growth Factor and Vascular Endothelial Fibroblast Growth Factor Families
    Hurley, M.M., Florkiewicz, R. Principles of Bone Biology 627-646
  • Systemic and Local Regulators of Bone Remodeling
    Hurley, M.M., Lorenzo, J.A. Bone Formation 44-70

Abstracts

  • BMP-2 Synergizes the Bone Healing Effect of Low Molecular Weight FGF-2 on Calvarial Defects in Mice
    Xiao, L., Catros, S., Ueno, D., Kuhn, L.T., Hurley, M.M. J. Bone Miner Res. 2012 Jan;27
  • HMWFGF2 Isoforms Regulate Bone Mineralization via Modulation of Pyrophosphate Genes in Mouse Bone Marrow Cultures
    Xiao, L., Hurley, M.M. J. Bone Miner Res 2012 Jan;27
  • Impaired Anabolic Action of PTH on Bone Formation in Fgf2 Knockout Mice is mediated by Attenuated Wnt Signaling
    Fei, Y., Xiao, L., Hurley, M.M. J. Bone Miner Res. 2012 Jan;27
  • Selective Knockout of HMWFGF2 Isoforms in Mice Increases Serum Phosphate and Increases Bone Formation In Vivo and In Vitro
    Xiao, L., Doetschman, T., Hurley, M.M. J. Bone Miner Res. 2012 Jan;27
  • Age Related Changes in FGF2 and Beta-Catenin Expression in Osteoblasts from Young, Middle Aged and Elderly Female
    Hurley, M.M., Esliger, A., Xiao, L. J. Bone Miner Res. 2011 Jan;26
  • Exported 18kDa Isoform of Fibroblast Growth Factor-2 Improved Bone Regeneration in Critical Size Mice Calvarial Defects
    Ueno, D., Xiao, L., Kuhn, L., Hurley, M.M. J. Bone Miner Res. 2011 Jan;26
  • HMW FGF2 Isoforms Regulate Bone Nodule Formation via Modulating FGFR/FGF23/ERK Signaling in BMSCs
    Xiao, L., Esliger, A., Hurley, M.M. J. Bone Miner Res. 2011 Jan;26
  • Positive Regulation of Osteoblasts Differentiation and Bone Formation is Partially Mediated by Modulation of the Wnt Pathway
    Fei, Y., Xiao, L., Doetschman, T., Coffin, D., and Hurley, M.M. 2011 Jan;
  • Serum Sclerostin Levels Correlate Positively with Bone Mineral Density at Multiple Skeletal Sites in Postmenopausal Women
    Jastrzebski, S., Kalinowski, J., Fei, Y., Choudhary, S., Pilbeam, C., Mirza, F., Hurley, M.M., Lorenzo, J. J. Bone Miner Res. 2011 Jan;26
  • Nuclear HMWFGF2 Isoforms are Novel Regulators of Fgf23 Promoter Activity in ROS17/2.8.Osteoblasts
    Xiao, L., Esliger, A., Hurley, M.M. J. Bone Miner Res. 2010 Jan;25
  • Phosphate Independent Effects of Nuclear HMWFGF2 Isoforms on Bone Formation In Vitro
    Xiao, L., Esliger, A., Hurley, M.M. J. Bone Miner Res. 2010 Jan;25
  • Disruption of the Fibroblast Growth Factor -2 Gene Resulted in Decreased Expression of Activating Transcription Factor 4
    Fei, Y., Xiao, L., Doetschman, T., Coffin, D., and Hurley, M.M. J. Bone Miner. Res 2009 Jan;24
  • Overexpression of the Nuclear HMW FGF2 Isoforms in Osteoblasts Results in Reduced Mineralization and Reduced Expression of their Nuclear Partner FIF
    Xiao, L., Fei, Y., Esliger, A., Coffin, J.D., Hurley, M.M. J. Bone Miner. Res. 2009 Jan;24
  • Targeted Overexpression of the Nuclear FGF2 Isoforms in Osteoblasts induces Hypophosphatemia via Modulation of FGF23 and Klotho in Mice
    Xiao, L., Coffin, J.D., Carpenter, T., Hurley, M.M. J. Bone Miner. Res. 2008 Jan;23S25
  • Overexpression of the Low Molecular Weight Isoform of FGF2 Partly Prevents Bone Loss in Ovariectomized Mice
    Xiao, L., Coffin, J.D., Hurley, M.M. J. Bone Miner. Res 2007 Jan;22S270
  • Transgenic Mice Expressing High Molecular Weight Isoforms of FGF2 Exhibits Decreased Bone Mass and Disturbed Phosphate Homeostasis
    Xiao, L., Li, X., Sobue, T., Coffin, J.D., Hurley, M.M. J. Bone Miner. Res. 2006 Jan;21S19
  • Endogenous FGF2 Is Critically Important in PTH Induction of Bcl2, Phosphorylation of CREB and Runx2 Nuclear Accumulation in Osteoblasts
    Agas, D., Sabbieti, M.G., Xiao, L., Naganawa, T., Hurley, M.M. J Bone Miner. Res. 2005 Jan;20S71
  • The Anabolic Response to Bone Morphogenetic Protein-2 is Impaired in Fibroblast Growth Factor-2 Null Mice
    Naganawa, T., Xiao, L., Coffin, J.D., Doetchman, T., Hurley, M.M. J Bone Miner Res 2004 Jan;19S60
  • Disruption of the FGF-2 Gene in Mice Reduces the Expression of Key Regulators of Osteoblast Precursor Proliferation and Differentiation
    Naganawa, T., Xiao, L., Abugunde, E., Sobue, T., Coffin, J.D., Hurley, M.M. J Bone Miner. Res. 2003 Jan;18S329
  • Fibroblast Growth Factor 2 Directly Inhibits Expression of Osterix mRNA in Osteoblastic Cells
    Abugunde, E., Lee, K., Naganawa, T., Xiao, L., Hurley, M.M. J Bone. Miner. Res. 2003 Jan;18S138
  • Phenotypic Characterization of Bones of Transgenic Mice Overexpressing Fibroblast Growth Factor-2
    Sobue, T., Xiao, L., Okada, Y., Tanaka, Y., Ito, M., Okimoto, N., Nakamura, T., Coffin, J.D., Hurley, M.M. J Bone Miner. Res. 2002 Jan;17S425
  • Prostaglandins increase FGF-2 and FGF Receptor Expression and Nuclear Accummulation in Osteoblasts via Mitogen Activated Protein Kinase
    Sabbieti, M.G., Marchetti, L., Menghi, M., Materazzi, S., Menghi, G., Raisz, L.G., Hurley, M.M. J. Bone Miner. Res. 2002 Jan;17S239
  • The Anabolic Effect of Parathyroid Hormone is Impaired in Bones of Fgf2 Null Mice
    Hurley, M.M., Okada, Y., Sobue, T., Zhang, X., Xiao, L., Tanaka, Y., Ito, M., Okimoto, N., Nakamura, T., Coffin, J.D., Rosen, C.J., Doetchman, T. J Bone Miner. Res. 2002 Jan;17S83
  • Disruption of the Fgf2 Gene in Mice Impairs Prostaglandin E2 Stimulation of Osteoclast Formation and Cyclo-Oxygenase-2 in Primary Osteoblastic Cells.
    Sobue, T., Okada, Y., Zhang, X., Coffin, J.D., Hurley, M.M. J Bone Miner. Res. 2001 Jan;16S490
  • In vivo Administration of Interleukin-1 Enhances Osteoblast Proliferation and Differeation in Ex-vivo Bone Marrow Cultures From Fgf2 Null Mice but not Osteoclast Formation in Calvariae of Fgf2 Null Mice
    Sobue, T., Zhang, X., Coffin, D., Hurley, M.M. J. Bone Miner. Res. 2001 Jan;16S198
  • Osteoclast Formation in Transgenic Mice Overexpressing Fibroblast Growth Factor 2
    Sobue, T., Zhang, X., L.G Raisz, Coffin, D., Hurley, M.M. Bone Miner. Res. 16 2001 Jan;S198
  • Interleukin-1 Regulates FGF2 Expression in Osteoblasts and IL-1 Induced Osteoclast Formation is Impaired in Fgf2 Null Mice
    Hurley, M.M., Zhang, X., Okada, Y., Min, Y.K., Raisz, L.G., Pilbeam, C.C., Florkiewicz, R., Coffin, J.D. Bone & Tooth Society. J. Bone Miner. Res 2000 Jan;
  • Overexpression of FGF-2 in Transgenic Mice Causes Premature and Enhanced Apoptotic Chondrocyte Cell Death at the Epiphyseal Growth Plate
    Hurley, M.M., Gronowicz, G., Nahounou, M., Cassarino, D., Clark, S., Sims, N.A., Baron, R., Martin, S., Coffin, D. J Bone & Miner Res 2000 Jan;S90
  • Endocrine Disrupting Chemicals and Growth Factors. In Vitro Effects of Pthalates on Rat Osteoblasts
    Menghi, G., Sabbieti, M.G., Marchetti, L., Hurley, M.M. Eur. J. Histochem 1999 Jan;432
  • Impaired Osteoclast Formation in Murine Bone Marrow Cultures of Fibroblast Growth Factor-2 Null Mice in Response to Parathyroid Hormone and Prostaglandin E2
    Okada, Y., Montero, A., Doetschman, T., Coffin, J.D., Hurley, M.M. J Bone Miner Res 1999 Jan;S241
  • Lectin Affinity Patterns in Rat Osteoblastic Py1a Cells
    Sabbieti, M.G., Marchetti, L., Hurley, M.M., Materazzi, S., Menghi, G. Eur. J. Histochem 1999 Jan;432
  • AP-1 and CRE sites jointly mediate the induction of prostaglandin G/H synthase-2 promoter activity basic fibroblast growth factor in osteoblastic MC3T3-E1 cells.
    Okada Y, Tetradis S, Voznesensky O S, Kream BE, Herschman HR, Hurley MM, Pilbeam CC. J Bone Miner Res 1998 Jan;13(S1)S245
  • Decreased osteoclastogenic responses in marrow cultures from mice with disruption of the PGHS-2 gene.
    Okada Y, Raisz LG, Lorenzo JA, Alander CB, Freeman A, Voznesensky OS, Hurley MM, Pilbeam CC. J Bone Miner Res 1998 Jan;13(S1)S330
  • Expression and regulation of fibroblast growth factor-2 by cytokines and growth factors in human osteoblasts.
    Hurley MM, Montero A, Abreu C, Min YK, Pilbeam C, Raisz, Hand A, Florkiewicz R. J Bone Miner Res 1998 Jan;13(S1)S440
  • Expression of D-Type Cyclins After bFGF Treatment of Human Osteosarcoma Cells and a Mouse Osteoblastic Cell Line
    Brown, M., Montero, A., Arnold, A., Hurley, M.M. Bone 1998 Jan;22(5):S206
  • Basic fibroblast growth factor stimulates bone resorption through mitogenic effects on immature osteoblastic cells as well as cyclooxygenase-2 induction.
    Kawaguchi H, Kurokawa T, Tanaka S, Pilbeam CC, Raisz LG, Hurley MM. J Bone Min Res 1997 Jan;12(S1)S209
  • Prostaglandins Regulate the Expression of Fibroblast Growth Factor-2 in Bone
    Sabbieti, M.G., Marchetti, L., Abreu, C., Hand, A., Raisz, L.G., Hurley, M.M. J Bone Miner Res 1997 Jan;S208
  • Basic Fibroblast Growth Factor Induces Osteoclastogenesis in Bone Marrow Cultures by a Prostaglandin Mediated Mechanism
    Hurley, M.M., Lee, S.K., Marcello, K., Abreu, C., Raisz, L.G., Bernecker, P., Lorenzo, J. J. Bone Miner. Res. 10 1995 Jan;1
  • Localization of an FGF-2 Inhibitory Element in the COL1A1 Gene in Transgenic Mice
    Hurley, M.M., Dodig, M., Abreu, C., Marcello, K., Mack, K., Clark, S., Cassarino, D., Lichtler, A. J. Bone Miner. Res. 10 1995 Jan;1
  • Regulation of inducible prostaglandin G/H synthase mRNA levels and promoter activity by basic fibroblast growth factor in osteoblastic cells.
    Kawaguchi H, Pilbeam C, Abreu C, Raisz L, Hurley M. J Bone Min Res 1994 Jan;9(S1)S124
  • Regulation of the Collagenase Promoter and Collagenase mRNA and Stimulation of Collagenase Activity by Basic Fibroblast Growth Factor in Osteoblastic MC3T3-E1 Cells
    Hurley MM, Marcello K, Abreu C, Brinckerhoff CE, Bowik CC, Hibbs M Arthritis & Rheumatism Suppl. 1994 Jan;37
  • Insulin like growth factor binding protein 5 accumulates in bone matrix and is released by parathyroid hormone and prostaglandin E2.
    Hakeda Y, Kawaguchi H, Hand A, Pilbeam C, Hurley M, Abreu C, Kumegawa M, Raisz LG. J Bone Miner Res 1993 Jan;8(S1)S237
  • Heparin Inhibits Collagen Synthesis and Steady-State Levels of Procollagen mRNA
    Hurley, M.M., Fall, P.M., Kream, B.E., Raisz, L.G. J Bone Miner Res 4 1989 Jan;
  • Effects of Ethanol and Acetaldehyde on Collagen Synthesis and Prostaglandin Release from 21-day Old Fetal Rat Calvaria
    Hurley, M.M., Kream, B.E., Raisz, L.G. J Bone Miner Res 1 1986 Jan;
  • Comparison of Effects on Auronofin, Gold Sodium Thiomalate, and Penicillamine on Bone Resorption
    Vargas, S.J., Jones, T.G., Hurley, M.M., Raisz, L.G. Calcif Tissue Int 1985 Jan;
  • Basic Fibroblast Growth Factor Inhibits IGF-1 mRNA in the Clonal Osteoblastic Cell Line MC3T3-E1
    Hurley, M.M., Abreu, C., Raisz, L.G., Kream, B.E. Bone and Mineral 17 89
  • Disruption of the Fibroblast Growth Factor 2 Gene in Mice Results in Diminished Formation of Osteoclasts in Bone Marrow Culture in Response to RANKL
    Zhang, X., Lorenzo, J., Coffin, D., Hurley, M.M. J Bone & Miner Res S50
  • Effect of Parathyroid Hormone (1-34) on Temporal Expression of Cell Growth, Growth Factors and Osteoblast Phenotype-Related Genes in Rat Bone Cells In Vivo
    Onyia, J.E., Tu, Y., Herring, J., Bidwell, J., Hurley, M.M., Hulman, J., Hock, J.M. J. Bone Miner. Res. 1
  • Expression of Basic Fibroblast Growth Factor (bFGF) by Human Blood Lymphocytes
    Verissimo, A., Hurley, M., Abreu, C., Forman, E., Paul, S., DeLisa, S., Sorba,, and Dainiak, N.
  • Expression of Basic Fibroblast Growth Factor mRNA Levels in Osteoblasts
    Hurley, M.M., Abreu, C., Lorenzo, J., Raisz, L.G. J Bone Miner Res. S127
  • Function of p21/p53 Pathway in regulating Chondrocyte Apoptosis and Proliferation in Dwarf Mice
    Hurley, M.M., Gronowicz, G., Cassarino, D., Clark, S., Sims, N., Baron, R., Amling, M., Brooks, D., Wischcamper, C., Lurie, D., Proetzel, G., Coffin, J.D. J Bone Miner. Res. 17S403
  • Functional Redundancy of FGFs in Odontogenesis
    Klingebiel, E., Hurley, M., Coffin, J.D., Mina, M. J. Den. Res. 79 (412):
  • Overexpression of FGF-2 Protein Isoforms in Osteoblasts. Effects on Proliferation and Differentiation
    Xiao, L., Liu, P., Sobue, T., Coffin, J., Hurley, M.M. J. Bone Miner. Res. 17S425
  • Prostaglandins Influence Lectin and Fibroblast Growth Factor-2 Distributional Patterns in Osteoblasts
    Sabbieti, M.G., Marchetti, L., Hurley, M.M., Materazzi, G., Menghi, G. Bone 23(5):S535
  • Regulation of NF-IL6 and IL-6 Expression by Basic Fibroblast Growth Factor in Osteoblastic MC3T3-E1 Cells
    Hurley, M.M., Abreu, C., Lorenzo, J., Ray, A., Gronowicz, G. J. Bone Miner Res 9 S164
  • Short Term Fibroblast Growth Factor Treatment Increases Osteoblast Differentiation and Bone Nodule Formation in Bone Marrow Cultures from Young and Adult Mice
    Hurley, M.M., Sobue, T., Zhang, X. J. Bone Miner. Res. 16S250
  • Signal Transduction by Basic Fibroblast Growth Factor in Rat Osteoblastic Py1a Cells
    Hurley, M.M., Marcello, K., Abreu, C., Kessler, M. J. Bone Miner. Res. 101
  • Stimulation of Fibroblast Growth Factor-2 mRNA Levels by Prostaglandins
    Montero, A., Sabbieti, M.G., Raisz, L.G., Abreu, C., Hurley, M.M. Bone (22):15S

Conference Papers

Reviews

Title or AbstractTypeSponsor/EventDate/YearLocation
Fracture Healing in Fgf2 Heterozygous and Homozygous Knockout MiceTalkFGF Fusion Conference2019Nassau Bahamas
High Molecular Weight Isoforms of Fibroblast Growth Factor 2, New Players in Osteoarthropathy”TalkAvioli Musculoskeletal Research Seminar2018Washington University, St Louis, MO
FGF2 isoforms and osteoarthritisTalkFGF Fusion Conference2017Cancun, Mexico
FGF2 Isoforms in Bone and Phosphate HomeostasisTalkChinese Academy of Science2016Beijing, China
Impaired Fracture Healing in Fgf2 Heterozygous and Homozygous Knockout Mice. Annual Meeting of the American Society for Bone & Mineral Research.TalkAmerican Society for Bone and Mineral Research2016Atlanta, Georgia
knockout of nuclear FGF2 isoforms modulate bone and phosphate homeostasisTalkGordon Conference2014Ventura, CA, USA
Exported 18kDa isoform of FGF2 and low dose BMP-2 improved bone regeneration in critical size mice calvarial defects via wnt signalingTalkOrthopedic Research Society2014New Orleans, LA, USA
Role of PTH in Fgf2 mutant and WT aged miceTalkUCONN-Jackson Laboratory Aging Symposium2014Storrs, CT, USA
Nuclear FGF2 isoforms inhibit bone marrow stromal cell mineralization through FGF23/FGFR/MAPK. TalkEndocrine Society2013San Francisco California
Nuclear FGF2 isoforms inhibit bone marrow stromal cell mineralization through FGF23/FGFR/MAPKTalkEndocrine Society2013San Francisco, USA
Impaired Anabolic Action of PTH on Bone Formation in Fgf2 Knockout Mice is Mediated by Attenuated Wnt SignalingTalkAmerican Society for Bone & Mineral Research2012Minneapolis, Minnesota
FGF2 nuclear isoforms and bone matrix mineralizationLectureGordon Research Conference2012Les Diablerets, Switzerland
FGF2 nuclear isoforms and bone matrix mineralizationTalkGordon conference2012Switzerland
The Impaired Anabolic Effect of PTH In the Absence of Endogenous FGF2 Is Partially Due to Reduced ATF4 ExpressionTalkAmerican Society for Bone & Mineral Research2011San Diego, California
FGF2 Positive Regulation of Osteoblasts Differentiation and Bone Formation is Partially Mediated by Modulation of the Wnt pathwayTalkExtracellular Matrix in Health and Disease Symposium2011Boston, Massachusetts
Anabolic Action of FGF2 on Bone Formation is Mediated in Part by Modulation of Wnt PathwayTalkUniversity of Connecticut Health Center2011Farmington, Connecticut
OsteoporosisLectureUniversity of Connecticut Health Center2011Farmington, Connecticut
Nuclear FGF2 Isoforms are novel regulators of phosphate Homeostasis”TalkFGF Gordon Conference2010Ventura, California
Effect Anabolic Factors on Bone and Fat Formation in Old Age”TalkUniversity of Connecticut School of Medicine Center on Aging2010University of Connecticut Health Center
Novel Effects of FGF23 Protein Isoforms on Bone Formation and Phosphate HomeostasisTalkAMGEN2009Thousand Oaks, California
FGFs and Bone” TalkEndocrine Society, Annual Meeting2009Washington DC
Diabetes Mellitus, Diagnosis and ManagementLectureUniversity of Connecticut2009West Hartford, Connecticut
Novel Effects of FGF2 Protein Isoforms on Bone Formation and Phosphate Homeostasis” TalkIndiana University School of Medicine2008Indianapolis, Indiana
“Effects of Global Knockout or Over-Expression Of Fibroblast Growth Factor-2 In Osteoblasts on Fracture Healing In Transgenic MiceTalkInternational Bone and Mineral Society2008Davos, Switzerland
The Exported 18kDa Isoform of FGF-2 is a Critical Determinant of Bone Mass in MiceTalkNew England Musculoskeletal Research Symposium2008Farmington, Connecticut
Targeted Overexpression of the Nuclear FGF2 Isoforms in Osteoblasts Induces Hypophosphatemia via Modulation of FGF23 and Klotho in MiceTalkAmerican Society for Bone & Mineral Research2008Montreal, Canada
FGF signaling pathways in bone formation and maintenance” TalkAmerican Academy of Orthopaedic Surgeons Research Symposium2007Miami, Florida
Role of Fibroblast Growth Factor-2 in AdipogenesisTalkUniversity of Connecticut Health Center2007Farmington, Connecticut
Diabetes Mellitus, Diagnosis and ManagementLectureUniversity of Connecticut2007Hartford, Connecticut
Osteoporosis and CytokinesLectureUniversity of Connecticut Health Center2007Farmington, Connecticut
Health Professions Partnership InitiativeLectureConnecticut State Legislature2007
Health Professions DiversityLectureSullivan Alliance National Leadership Symposium2007Washington, DC
“PTH induced Osteoclastogenesis and Osteoblastogenesis is markedly impaired in bone marrow cultures of Fgf2 knockout mice”. TalkUniversity of Camerino2006Camerino, Italy
“Disruption of the Fgf2 Gene activates the adipogenic and suppresses the osteogenic program in Marrow stromal cells. TalkAmerican Society of Bone & Mineral Research Annual Meeting2006Philadelphia, PA
"Role of Exported and Intracellular FGF-2 Isoforms in BoneTalkFGF Gordon Research Conference2006Ventura, California
Transgenic Mice Expressing High Molecular Weight Isoforms of FGF2 Exhibits Decreased Bone Mass and Disturbed Phosphate HomeostasisTalkAmerican Society for Bone & Mineral Research2006Philadelphia, Pennsylvania
FGF-2 and Musculoskeletal AgingTalkUniversity of Connecticut Health Center2006Farmington, Connecticut
Fibroblast Growth Factors in BoneTalkUniversity of Connecticut Health Center Musculoskeletal Institute2006Farmington, Connecticut
Osteoporosis and CytokinesLectureUniversity of Connecticut Health Center2006Farmington, Connecticut
Fibroblast Growth Factor2: Paracrine and Intracrine Effects on BoneTalkYale, School of Medicine2005New Haven, CT
Osteoporosis and CytokinesLectureUniversity of Connecticut Health Center2005Farmington, Connecticut
The UCHC Health Professions Partnership Initiative as a Successful Model of Connecticut Career ChoicesLectureThe Governor’s Office for Workforce Development2005Rocky Hill, Connecticut
The Exported 18 kDa Isoform of FGF2 is a Critical Determinant of Bone Mass in MiceTalkAmerican Society for Bone & Mineral Research2004Seattle, Washington
Regulation of Bone Formation by the FGF2 PathwayTalkAnnual Symposium on Calcified Tissues2004Nice, France
Fibroblast Growth Factor-2 and Bone RemodelingTalkNIH and The American Society for Bone and Mineral Research2004Washington, D.C.
Osteoporosis of Mice and Men, Anabolic Response to PTHLectureUniversity of Connecticut Health Center2004Farmington, Connecticut
Osteoporosis and CytokinesLectureUniversity of Connecticut Health Center2004Farmington, Connecticut
UCHC Health Professions Partnership InitiativeTalkAssociation of American Medical Colleges2004Boston, Massachusetts
Sustainability of the Health Professions Partnership InitiativeTalkAssociation of American Medical Colleges2004Scottsdale, Arizona
The Transcription Factor STAT1 is a Novel Negative Regulator of Bone Mass and Bone FormationTalkAmerican Society for Bone and Mineral Research2003Minneapolis, Minnesota
Osteoporosis and CytokinesLectureUniversity of Connecticut Health Center2003Farmington, Connecticut
“Fibroblast Growth Factor-2 and Bone Remodeling”, TalkEndocrine Society, Annual Meeting2002San Francisco, CA
The Anabolic Effect of Parathyroid Hormone is Impaired in Bones of Fgf2 Null MiceTalkAmerican Society for Bone and Mineral Research2002San Antonio, Texas
Osteoporosis, What is it?LectureUniversity of Connecticut Health Center2002Farmington, Connecticut
“Disruption of the Fgf2 gene in mice results in impaired bone formation TalkWesleyan University2001Middletown, CT
“Disruption of the fibroblast growth factor gene in mice results in diminished formation of osteoclasts in bone marrow culture in response to Prostaglandins”. TalkUniversity of Montana2001Missoula, Montana
Prostaglandins Regulate FGF-2 and FGF Receptor Expression and Subcellular Localization in OsteoblastsTalkInternational Bone & Mineral Society and the European Calcified Tissue2001Madrid, Spain
An Overall Perspective on Women’s HealthLectureUniversity of Connecticut School of Allied Health2001Farmington, Connecticut
“Disruption of the fibroblast growth factor gene in mice results in diminished formation of osteoclasts in bone marrow culture in response to RANKL”TalkAmerican Society of Bone & Mineral Research Annual Meeting2000Toronto, Canada
Regulation of Fibroblast Growth Factor-2 and Fibroblast Growth Factor Receptors by Transforming Growth Factor Beta in Human Osteoblastic MG-63 CellsTalkInternational Conference on Progress in Bone and Mineral Research2000Vienna, Austria
Overexpression of FGF-2 in Transgenic Mice Causes Premature and Enhanced Apoptotic Chondrocyte Cell Death at the Epiphyseal Growth PlateTalkAmerican Society of Bone and Mineral Research2000Toronto, Canada
Disruption of the Fibroblast Growth Factor-2 Gene in Mice Results in Decreased Bone Mass and Bone FormationTalkUniversity of Camerino2000Camerino, Italy
Prostaglandin Induced Osteoclastogenesis is Markedly Impaired in Bone Marrow Cultures of Fgf2 Knockout MiceTalkUniversity of Camerino2000Camerino, Italy
Interleukin-1 and Prostaglandins Regulate Fibroblast Growth Factor-2 Gene Expression in OsteoblastsTalkUniversity of Connecticut Health Center2000Farmington, Connecticut
Disruption of the Fibroblast Growth Factor-2 Gene in Mice Results in Decreased Bone Mass and Bone FormationTalkUniversity of Connecticut Health Center2000Farmington, Connecticut
Disruption of the Fibroblast Growth Factor-2 Gene in Mice Results in Decreased Bone Mass and Bone FormationTalkAmerican Society of Bone and Mineral Research Meeting1999
Fibroblast Growth Factors in Bone RemodelingTalkUniversity of Connecticut School of Dental Medicine1999Farmington, Connecticut
Bone MetabolismLectureUniversity of Connecticut Health Center1999Farmington, Connecticut
Osteoporosis and CytokinesLectureUniversity of Connecticut Health Center1999Farmington, Connecticut
Epiphysial Growth Plate Defects in Basic FGF Transgenic and FGF-2 Null MiceTalkAmerican Society of Biochemistry and Molecular Biology1998Taos, New Mexico
Fibroblast Growth Factors in Bone RemodelingTalkUniversity of Connecticut School of Dental Medicine1998Farmington, Connecticut
Bone MetabolismTalkUniversity of Connecticut Health Center1998Farmington, Connecticut
Role of Prostaglandins in FGF-2 Mediated OsteoclastogenesisTalkUniversity of Camerino1998Camerino, Italy
Prostaglandins and FGF-2 Mediated OsteoclastogenesisTalkUniversity of Connecticut Health Center1998Farmington, Connecticut
Localization of an FGF-2 Inhibitory Element in the COL1A1 Gene in Transgenic MiceTalkUniversity of Pennsylvania1998Philadelphia, Pennsylvania
Osteoporosis and CytokinesLectureUniversity of Connecticut Health Center1998Farmington, Connecticut
Osteoporosis The Silent DiseaseLectureWest Indian Foundation1998Hartford, Connecticut
Osteoporosis The Silent DiseaseLectureWVIT-TV Channel 301998New Britain, Connecticut
Regulation of FGF-2 in BoneTalkUniversity of Connecticut Health Center1997Farmington, Connecticut
Regulation of FGF-2 in BoneTalkPrizm Pharmaceuticals1996San Diego, California
Adrenal DisorderLectureUniversity of Connecticut School of Medicine1995Farmington, Connecticut
Regulation of Inducible Prostaglandin G/H Synthase mRNA Levels and Promoter Activity by Basic Fibroblast Growth Factor in Osteoblastic CellsTalkAmerican Society for Bone & Mineral Research1994Kansas City, Missouri
Osteoporosis and Growth FactorsLectureUniversity of Connecticut School of Medicine1994Farmington, Connecticut
HypoparathyroidismLectureUniversity of Connecticut School of Medicine1994Farmington, Connecticut
Basic Fibroblast Growth Factor Expression and Regulation in Bone CellsTalkUniversity of Connecticut1993Farmington, Connecticut
HirsutismLectureUniversity of Connecticut School of Medicine1993Farmington, Connecticut
Basic Fibroblast Growth Factor Inhibits IGF-1 mRNA in the Clonal Osteoblastic Cell Line MC3T3-E1TalkInternational Conference on Calcium Regulating Hormones1992Florence, Italy
Adrenal InsufficiencyLectureUniversity of Connecticut School of Medicine1992Farmington, Connecticut
Mechanisms by which Heparin and Heparin Binding Growth Factors Act on Type I Collagen Synthesis in BoneTalkUniversity of Connecticut Department of Medicine1991Farmington, Connecticut
Connective Tissue Matrix ProteinsLectureUniversity of Connecticut School of Medicine1991Farmington, Connecticut
Adrenal InsufficiencyLectureUniversity of Connecticut School of Medicine1991Farmington, Connecticut
Pagets DiseaseLectureUniversity of Connecticut School of Medicine1990Farmington, Connecticut
Cell CycleLectureUniversity of Connecticut School of Medicine1989Farmington, Connecticut
HirsutismLectureUniversity of Connecticut School of Medicine1989Farmington, Connecticut
Systemic HormonesLectureUniversity of Connecticut School of Medicine1988Farmington, Connecticut
HirsutismLectureUniversity of Connecticut School of Medicine1987Farmington, Connecticut
Amenorrhea and InfertilityLectureSt. Joseph’s College1986West Hartford, Connecticut