Photo of Jaime  Imitola, M.D.

Jaime Imitola, M.D.

Professor of Neurology, Genetics and Genome Sciences, and Neuroscience
Vice Chair for Research, Department of Neurology
Director, Division of Multiple Sclerosis and Translational Neuroimmunology
NPI Number:
Academic Office Location:
UConn Health
263 Farmington Avenue
Farmington, CT 06030-5357
Phone: 860-679-3186

Multiple Sclerosis

Imitola Lab

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Dr. Imitola is a Professor of Neurology, Genetics, and Neuroscience and is the Director of the Multiple Sclerosis (MS) Center, Chief of the Division of MS and Neuroimmunology, and Vice Chair of Research in the Department of Neurology at UConn Health. In collaboration with a multidisciplinary team, he has grown the clinical program for MS/Neuroinflammation and lifespan Neuroimmune disorders at UConn Health, making UConn Health a top choice for MS care in the state of Connecticut. The Program is now nationally recognized as a Comprehensive Center for MS care and a national leader in MS care in diverse populations. He is leading and creating novel innovative models of MS care to prevent progression in MS throughout the lifespan. Dr. Imitola has more than 165 papers, abstracts, and book chapters on stem cells and neuroinflammation primarily focusing on cortical damage in animal models of MS and the ethics of stem cell tourism. He has multiple accolades and awards, including the William Silen Award, John Whitaker Award, and the 2020 Inspiration Award from the National MS Society.  He is a Fellow of the American Academy of Neurology (AAN) and the American Neurological Association (ANA). His work has been funded by NIH, the National MS Society, and industry grants. 

M.D.University of Cartagena Faculty of MedicineMedicine

Post-Graduate Training
InternshipHospital Militar Central, ColumbiaMedicine
FellowshipNeurologic and Human Genetics Institute, Javeriana University, ColumbiaResearch and Clinical Fellow in Neurology and Genetics
PostdoctoralBrigham and Women’s Hospital, Harvard Medical SchoolPostdoctoral Fellow in Brain Tumor Biology, Neurosurgery
FellowshipBrigham and Women’s Hospital, Harvard Medical SchoolResearch Fellow in Neurology
PostdoctoralBrigham and Women’s Hospital, Harvard Medical SchoolPostdoctoral Fellow in Multiple sclerosis and Neuroimmunology
ResidencyTemple University HospitalInternal Medicine
ResidencyTemple University HospitalNeurology (Chief 2011-2012)
FellowshipThomas Jefferson University Hospital for NeuroscienceMultiple Sclerosis

Name of Award/HonorAwarding Organization
American Academy of Neurology Annual Meeting (AANAM), Course Director “Diagnosis and Treatment of MS in Diverse population”.American Academy of Neurology
Selected as one of the Top Doctors in Connecticut (2021-2023)Connecticut Magazine
Fellow of the American Neurological Association (FANA)American Neurological Association (FANA)
UConn Graduate Faculty Career Mentor of the Year Award (Student nominated)UConn Center for Career Development.
Volunteer Inspiration AwardNational MS Society
Dean's ListOhio State University College of Medicine
Selected as a Top DoctorCentral Ohio-Columbus Monthly
Research Award for Outstanding Publication FacultyNeurological Institute Ohio State University
Research Grant AwardNeurological Institute Ohio State University
Elected FellowAmerican Academy of Neurology (ANN)
Accepted into the Early Career Reviewer (ECR) ProgramCenter for Scientific Review (CSR), National Institutes of Health
Research Grant AwardNeurological Institute Ohio State University
Top DoctorCastle and Connolly
Distinguished MS - Montreal LecturerMcGill University, Montreal
The John N. Whitaker Prize for MS ResearchACTRIMS
Distinguished Whitaker ScholarACTRIMS
Resident Excellence in Teaching Award, Department of NeurologyTemple University School of Medicine
Matthew T. Moore Neurology Resident Award, Department of NeurologyTemple University School of Medicine
Gordon Neurology Resident Award, Department of NeurologyTemple University School of Medicine
Gordon Neurology Resident Award, Department of NeurologyTemple University School of Medicine
The Ruth and William Silen, M.D. AwardBiomedical Science Careers Program and Harvard Medical School
Five Year Service AwardBrigham and Women's Hospital
Selected Research for Highlights in the XIX MeetingAmerican Academy of Neurology
M.D. With Distinction Top 5% of the ClassUniversity of Cartegena Faculty of Medicine
University Scholarship Award in PharmcologyUniversity of Cartegena Faculty of Medicine

Dr. Imitola is a board-certified neurologist with clinical expertise in aggressive and progressive multiple sclerosis, late onset multiple sclerosis, neuromyelitis optica spectrum disorder, neurosarcoidosis, transverse myelitis, Susac syndrome, central nervous system vasculitis, chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS), neurologic complications of systemic autoimmunity and cancer immunotherapy, genetic mimics of multiple sclerosis such as adult leukodystrophies, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), and hereditary diffuse leukoencephalopathy with spheroids (HDLS).

Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
UConn MD PHD Executive CommitteeAdvisory CommitteeMemberUniversity2022
International Society for Stem Cell Research (ISSCR).Professional/Scientific OrganizationVice-Chair Education CommitteeExternalInternational2022
FY21 CDMRP MSRP AP-1 multiple sclerosis peer review panel for the Department of Defense (DOD) Congressionally Directed Medical Research Programs (CDMRP).Study SectionReviewerExternalInternational20212021
Ask an Expert: Aging in MS National MS Society English VersionProfessional/Scientific OrganizationGuest SpeakerExternalNational20202020
Ask an Expert: Aging in MS National MS Society Spanish VersionProfessional/Scientific OrganizationGuest SpeakerExternalNational20202020
COVID19 Vaccines for MS patients TaskforceProfessional/Scientific OrganizationMemberExternalNational20202020
Invited Speaker for the National MS society Ask an Expert MS and AGING-SPANISHProfessional/Scientific OrganizationGuest SpeakerExternalNational20192020
Ask an expert: COVID19 and MS National MS Society-SPANISH VERSIONAdvisory CommitteeGuest SpeakerExternalNational
Panelist: Progressive MS in diverse population- Annual Meeting Scientific advisory board and Board of DirectorsProfessional/Scientific OrganizationGuest SpeakerExternalNational
MS Society CT-RI Chapter Board of TrusteeAdvisory CommitteeTrusteeRegional
National Medical Advisory Committee MS SocietyAdvisory CommitteeMemberExternalNational

Dr. Imitola is a physician-scientist interested in progressive MS, neurodegeneration, and repair and has been studying these processes for the last 15 years. At the bedside, he is working on understanding the impact of social determinants of health in the biological progression of complex MS patients and real-world strategies for prevention of MS. At  the bench, he leads a team that works on human models of neurological diseases using advanced, 3D stem cell cultures and bioengineering principles. With these techniques, he aims to identify new targets for next-generation medications for molecular prevention of neurodegeneration and improving repair in MS.  His lab’s research can be explored through his lab website. At UConn Health, Dr. Imitola is a member of the MD-PhD executive committee that helps with training physician-scientists. He is member of the National MS Society National Medical Advisory Committee (NMAC) and on the Board of Trustees of the National MS Society, Connecticut-Rhode Island Chapter. He is the Vice Chair of the education committee at the International Society for Stem Cell Research (ISSCR), where he is focusing on stem cell education for clinicians around the world.

He has mentored and trained dozens of  fellows, residents, and medical students, efforts that were recognized with the 2023 UConn Mentor of the Year Award.

Journal Articles


Case Reports