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Jaime Imitola Herrera, M.D.Associate Professor of Neurology, Genetics and Genome Sciences, and NeuroscienceVice Chair for Research, Department of Neurology Director, Division of Multiple Sclerosis and Translational Neuroimmunology
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Degree | Institution | Major |
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M.D. | University of Cartagena Faculty of Medicine | Medicine |
Post-Graduate Training
Training | Institution | Specialty |
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Internship | Hospital Militar Central, Columbia | Medicine |
Fellowship | Neurologic and Human Genetics Institute, Javeriana University, Columbia | Research and Clinical Fellow in Neurology and Genetics |
Postdoctoral | Brigham and Women’s Hospital, Harvard Medical School | Postdoctoral Fellow in Brain Tumor Biology, Neurosurgery |
Fellowship | Brigham and Women’s Hospital, Harvard Medical School | Research Fellow in Neurology |
Postdoctoral | Brigham and Women’s Hospital, Harvard Medical School | Postdoctoral Fellow in Multiple sclerosis and Neuroimmunology |
Residency | Temple University Hospital | Internal Medicine |
Residency | Temple University Hospital | Neurology (Chief 2011-2012) |
Fellowship | Thomas Jefferson University Hospital for Neuroscience | Multiple Sclerosis |
Awards
Name of Award/Honor | Awarding Organization |
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Volunteer Inspiration Award | National MS Society |
Dean's List | Ohio State University College of Medicine |
Selected as a Top Doctor | Central Ohio-Columbus Monthly |
Research Award for Outstanding Publication Faculty | Neurological Institute Ohio State University |
Research Grant Award | Neurological Institute Ohio State University |
Elected Fellow | American Academy of Neurology (ANN) |
Accepted into the Early Career Reviewer (ECR) Program | Center for Scientific Review (CSR), National Institutes of Health |
Research Grant Award | Neurological Institute Ohio State University |
Top Doctor | Castle and Connolly |
Distinguished MS - Montreal Lecturer | McGill University, Montreal |
The John N. Whitaker Prize for MS Research | ACTRIMS |
Distinguished Whitaker Scholar | ACTRIMS |
Resident Excellence in Teaching Award, Department of Neurology | Temple University School of Medicine |
Matthew T. Moore Neurology Resident Award, Department of Neurology | Temple University School of Medicine |
Gordon Neurology Resident Award, Department of Neurology | Temple University School of Medicine |
Gordon Neurology Resident Award, Department of Neurology | Temple University School of Medicine |
The Ruth and William Silen, M.D. Award | Biomedical Science Careers Program and Harvard Medical School |
Five Year Service Award | Brigham and Women's Hospital |
Selected Research for Highlights in the XIX Meeting | American Academy of Neurology |
M.D. With Distinction Top 5% of the Class | University of Cartegena Faculty of Medicine |
University Scholarship Award in Pharmcology | University of Cartegena Faculty of Medicine |
Dr. Imitola is a board-certified neurologist with clinical expertise in aggressive and progressive multiple sclerosis, late onset multiple sclerosis, neuromyelitis optica spectrum disorder, neurosarcoidosis, transverse myelitis, Susac syndrome, central nervous system vasculitis, chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS), neurologic complications of systemic autoimmunity and cancer immunotherapy, genetic mimics of multiple sclerosis such as adult leukodystrophies, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), and hereditary diffuse leukoencephalopathy with spheroids (HDLS).
Multiple Sclerosis
Neural Stem Cells and Neuroinflammation
Glioma Immunogenetics
Microglia Biology
Medical Genetics and Computational Biology
Journal Articles
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Therapeutic opportunities for targeting cellular senescence in progressive multiple sclerosis.
Current opinion in pharmacology 2022 Feb;63102184
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Real-world experience of ocrelizumab initiation in a diverse multiple sclerosis population.
Multiple sclerosis and related disorders 2021 May;53103021
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The APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies.
Neurology 2021 Apr;
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Babesia microti infection in a patient with multiple sclerosis treated with ocrelizumab.
Multiple sclerosis and related disorders 2021 Feb;48102731
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Generation of Neurosphere-Derived Organoid-Like-Aggregates (NEDAS) from Neural Stem Cells.
Current protocols 2021 Feb;1(2):e15
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Preventive neurology concepts for training the next-generation and closing gaps in real-world Multiple Sclerosis Care.
Multiple sclerosis and related disorders 2020 Nov;47102631
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Electrophysiological Maturation of Cerebral Organoids Correlates with Dynamic Morphological and Cellular Development.
Stem cell reports 2020 Sep;
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Inflammatory Mediators in Glioma Microenvironment Play a Dual Role in Gliomagenesis and Mesenchymal Stem Cell Homing: Implication for Cellular Therapy.
Mayo Clinic proceedings. Innovations, quality & outcomes 2020 Aug;4(4):443-459
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Complications from "Stem Cell Tourism" in Neurology.
Annals of neurology 2020 Jul;
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Aggressive multiple sclerosis (1): Towards a definition of the phenotype.
Multiple sclerosis (Houndmills, Basingstoke, England) 2020 Jun;1352458520925369
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Aggressive multiple sclerosis (2): Treatment.
Multiple sclerosis (Houndmills, Basingstoke, England) 2020 Jun;1352458520924595
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A possible link between intracranial lipomas and localization-related relapses in multiple sclerosis.
Multiple sclerosis and related disorders 2019 Nov;38101502
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Convergence of human cellular models and genetics to study neural stem cell signaling to enhance central nervous system regeneration and repair.
Seminars in cell & developmental biology 2019 Nov;9584-92
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Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation.
Nature communications 2019 Jan;10(1):217
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PRMT5 as a druggable target for glioblastoma therapy.
Neuro-oncology 2018 May;20(6):753-763
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A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.
Science translational medicine 2017 Dec;9(421):
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iPhemap: an atlas of phenotype to genotype relationships of human iPSC models of neurological diseases.
EMBO molecular medicine 2017 Dec;9(12):1742-1762
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Endogenous repair and development inspired therapy of neurodegeneration in progressive multiple sclerosis.
Expert review of neurotherapeutics 2017 Jun;17(6):611-629
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Selection of Patients With Multiple Sclerosis to Undergo Autologous Hematopoietic Stem Cell Transplantation.
JAMA neurology 2017 Apr;74(4):392-394
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Big-Data-Driven Stem Cell Science and Tissue Engineering: Vision and Unique Opportunities.
Cell stem cell 2017 Feb;20(2):157-160
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PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells.
Oncogene 2017 Jan;36(2):263-274
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Progressive multifocal leukoencephalopathy in a patient without apparent immunosuppression.
Journal of neurovirology 2016 Oct;22(5):683-687
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Deletion 2q37 syndrome: Cognitive-behavioral trajectories and autistic features related to breakpoint and deletion size.
American journal of medical genetics. Part A 2016 Sep;170(9):2282-91
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Cortical Volume Loss and Neurologic Dysfunction in Multiple Sclerosis.
JAMA neurology 2016 Aug;73(8):910-2
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The APOSTEL recommendations for reporting quantitative optical coherence tomography studies.
Neurology 2016 Jun;86(24):2303-9
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Standardized orthotopic xenografts in zebrafish reveal glioma cell-line-specific characteristics and tumor cell heterogeneity.
Disease models & mechanisms 2016 Feb;9(2):199-210
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Cell surface glycan engineering of neural stem cells augments neurotropism and improves recovery in a murine model of multiple sclerosis.
Glycobiology 2015 Dec;25(12):1392-409
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A novel 2q37 microdeletion containing human neural progenitors genes including STK25 results in severe developmental delay, epilepsy, and microcephaly.
American journal of medical genetics. Part A 2015 Nov;167A(11):2808-16
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Responsibilities of Health Care Professionals in Counseling and Educating Patients With Incurable Neurological Diseases Regarding "Stem Cell Tourism": Caveat Emptor.
JAMA neurology 2015 Nov;72(11):1342-5
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Rapid dissemination of granular cell astrocytoma arising from periventricular stem cell regions in chronic multiple sclerosis.
Journal of neuro-oncology 2015 Aug;124(1):147-9
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Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy.
Journal of immunology (Baltimore, Md. : 1950) 2015 Jun;194(11):5085-93
Case Reports
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Fraternal twins with autism, severe cognitive deficit, and epilepsy: diagnostic role of chromosomal microarray analysis.
Seminars in pediatric neurology 2014 Jun;21(2):167-71
Editorials
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Regenerative neuroimmunology: The impact of immune and neural stem cell interactions for translation in neurodegeneration and repair.
Journal of neuroimmunology 2019 Jun;3311-3
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New age for progressive multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2019 Apr;116(18):8646-8648
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Is no evidence of disease activity a realistic goal for patients with multiple sclerosis?
JAMA neurology 2015 Feb;72(2):145-7
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The cerebrospinal fluid-stem cell interactions as target for regenerative therapy in neurological diseases.
Stem cells and development 2015 Jan;24(2):145-6
Letters
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Letter in Reply: Toward a COVID-19 Vaccine Strategy for Pemphigus Patients on Rituximab.
Journal of the American Academy of Dermatology 2020 Oct;
Reviews
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Concise review: modeling multiple sclerosis with stem cell biological platforms: toward functional validation of cellular and molecular phenotypes in inflammation-induced neurodegeneration.
Stem cells translational medicine 2015 Mar;4(3):252-60