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                Yusuf M. Khan, PhDAssociate Professor of Orthopedic SurgeryAssociate Director, Skeletal Biology and Regeneration Area of Concentration-Biomedical Science Ph.D. program 
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                Education
                
                                    
Awards
            
                                    | Degree | Institution | Major | 
|---|---|---|
| BA | Boston University | Psychology | 
| MS | Drexel University | Biomedical Engineering | 
| PhD | Drexel University | Biomedical Engineering | 
Awards
| Name of Award/Honor | Awarding Organization | 
|---|---|
| Symposium Proceedings Ribbon Award | Materials Research Society | 
| Whitaker Travel and Professional Development Award | |
| Tissue Engineering Special Interest Group Graduate Student Award, Society for Biomaterials Annual Meeting, Reno, NV | |
| Orthopaedic Special Interest Group Graduate Student Award, Annual Meeting, Tampa Bay, FL | |
| Calhoun Fellow, 2000-2005 | Drexel University | 
| Certificate of Recognition | Sigma Xi Research Society | 
| Name & Description | Category | Role | Type | Scope | Start Year | End Year | 
|---|---|---|---|---|---|---|
| Session organizer and co-Chair, Regenerative Engineering: Stem Cells and Mechanotransduction, 2019 AIChE Annual Meeting, Orlando FL | Workshop/Conference | Session organizer and chair | External | National | 2019 | 2020 | 
| Session organizer and co-Chair, Substrate-derived Control of Cell Behavior, 2019 AIChE Annual Meeting, Orlando FL | Workshop/Conference | Session organizer and chair | External | National | 2019 | 2020 | 
| Grant Review: Immune System Regulation (ISR) peer review panel of 2018 Reconstructive Transplant Research Program within the Department of Defense CDMRP. | Study Section | grant reviewer | External | National | 2018 | 2018 | 
| Editorial board member, Journal of Biomedical Materials Research, Part A | Editorial Board | member | External | International | 2015 | 2021 | 
| Creating a Biomaterials Curriculum. 2011 Society for Biomaterials | Education Committee | Session Chair | External | National | 2011 | 2011 | 
| Scaffold Assisted Bone Defect Repair/Regeneration | Education Committee | Session Chair | External | National | 2011 | 2011 | 
| Journal of Tissue Science & Engineering | Professional/Scientific Journal | Reviewer | External | National | 2011 | |
| Institute of Medicine’s Committee on the Public Health Effectiveness of the FDA 510(k) Clearance Process | Education Committee | member | External | National | 2010 | 2011 | 
| Growth Factors | Professional/Scientific Journal | Reviewer | External | National | 2010 | |
| LCME Task Force | Education Committee | Member | UConn Health | Local | 2009 | |
| Orthopaedic Biomaterials Special Interest Group, Society for Biomaterials | Professional/Scientific Organization | Program Chair | External | National | 2009 | 2011 | 
| Journal of Applied Polymer Science | Professional/Scientific Journal | Reviewer | External | National | 2009 | |
| Society for Biomaterials | Professional/Scientific Organization | Session Chair | External | National | 2008 | 2008 | 
| International Journal of Molecular Sciences | Professional/Scientific Journal | Reviewer | External | International | 2008 | |
| Journal of Arthroplasty | Professional/Scientific Journal | Reviewer | External | National | 2008 | |
| Clinical Orthopaedics and Related Research | Professional/Scientific Journal | Reviewer | External | National | 2008 | |
| ASTM | Professional/Scientific Organization | Member | External | National | 2007 | 2010 | 
| Society for Biomaterials | Professional/Scientific Organization | Vice Chair | External | National | 2007 | 2009 | 
| Society for Biomaterials | Professional/Scientific Organization | Vice Chair | External | National | 2007 | 2011 | 
| American Society for Testing and Materials | Professional/Scientific Organization | Member | External | National | 2007 | 2010 | 
| American Academy of Orthopaedic Surgeons | Professional/Scientific Organization | Organizer/Panel member | External | National | 2007 | 2007 | 
| Recent Patents on Biomedical Engineering | Editorial Board | Reviewer | External | National | 2007 | |
| Journal of Orthopaedic Research | Professional/Scientific Journal | Reviewer | External | National | 2007 | |
| Acta Biomaterialia | Professional/Scientific Journal | Reviewer | External | National | 2007 | |
| Bone | Professional/Scientific Journal | Reviewer | External | National | 2007 | |
| Journal of Biomedical Materials Research (Part A) | Professional/Scientific Journal | Reviewer | External | National | 2006 | |
| Journal of Biomedical Materials Research (Part B) | Professional/Scientific Journal | Reviewer | External | National | 2006 | |
| Tissue Engineering | Professional/Scientific Journal | Reviewer | External | National | 2006 | |
| Society for Biomaterials | Professional/Scientific Organization | Member | External | National | 2005 | |
| Orthopaedic Research Society | Professional/Scientific Organization | Member | External | National | 2005 | 
Not accepting lab rotation students at this time for Fall 2025/Spring 2026
Journal Articles
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                                        3D force microscopy for volumetric quantification of ultrasound-induced loading: applications for bone repair.
                                    Biomechanics and modeling in mechanobiology 2025 Sep;
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                                        Ultrasound-derived Mechanical Stimulation of Alginate Hydrogels for Bone Repair: An in vitro study.
                                    Journal of Regenerative Engineering and Translational Medicine 2023 Mar;
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                                        Ultrasound-derived mechanical stimulation of cell-laden collagen hydrogels for bone repair.
                                    Journal of biomedical materials research. Part A 2023 Feb;
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                                        The Treatment of Muscle Atrophy after Rotator Cuff Tears Using Electroconductive Nanofibrous Matrices.
                                    Regenerative engineering and translational medicine 2021 Mar;
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                                        Bone Flap Resorption in Pediatric Patients Following Autologous Cranioplasty.
                                    Operative neurosurgery (Hagerstown, Md.) 2021 Jan;
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                                        Biomimetic electroconductive nanofibrous matrices for skeletal muscle regenerative engineering.
                                    Regenerative engineering and translational medicine 2020 Jun;6(2):228-237
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                                        Biomimetic Electroconductive Nanofibrous Matrices for Skeletal Muscle
                                    Regenerative Engineering and Translational Medicine 2019 Dec;6(2):228-237
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                                        Large scale segmental bone defect healing through the combined delivery of VEGF and BMP-2 from biofunctionalized cortical allografts.
                                    Journal of biomedical materials research. Part B, Applied biomaterials 2018 Oct;
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                                        Nanofiber/Microsphere Hybrid Matrices In Vivo for Bone Regenerative Engineering: A Preliminary Report.
                                    Regenerative engineering and translational medicine 2018 Sep;4(3):133-141
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                                        Cell responses to physical forces, and how they inform the design of tissue-engineered constructs for bone repair: a review
                                    Journal of Materials Science 2018 Apr;531-21
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                                        Microsphere-Based Scaffolds in Regenerative Engineering.
                                    Annual review of biomedical engineering 2017 Jun;19135-161
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                                        Mechanically Loading Cell/Hydrogel Constructs with Low Intensity Pulsed Ultrasound for Bone Repair.
                                    Tissue engineering. Part A 2017 Jun;24254-263
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                                        Dual growth factor delivery from biofunctionalized allografts: Sequential VEGF and BMP-2 release to stimulate allograft remodeling.
                                    Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2016 May;351086-1095
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                                        Simple signaling molecules for inductive bone regenerative engineering.
                                    PloS one 2014 Jul;9(7):e101627
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                                        Thiol-acrylate nanocomposite foams for critical size bone defect repair: A novel biomaterial.
                                    Journal of biomedical materials research. Part A 2013 Apr;101(12):3531-41
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                                        Regenerative engineering.
                                    Science translational medicine 2012 Nov;4(160):160ed9
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                                        The enhancement of bone allograft incorporation by the local delivery of the sphingosine 1-phosphate receptor targeted drug FTY720.
                                    Biomaterials 2010 Sep;31(25):6417-24
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                                        Tissue-engineered matrices as functional delivery systems: adsorption and release of bioactive proteins from degradable composite scaffolds.
                                    Journal of biomedical materials research. Part A 2010 Aug;94(2):568-75
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                                        Functionalization of chitosan/poly(lactic acid-glycolic acid) sintered microsphere scaffolds via surface heparinization for bone tissue engineering.
                                    Journal of biomedical materials research. Part A 2010 Jun;93(3):1193-208
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                                        Barriers to timely screening colonoscopy: the role of health insurance.
                                    Connecticut medicine 2010 Apr;74(4):201-6
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                                        A Critical Assessment of the Clinical Efficacy and Cellular Response to Low Intensity Pulsed Ultrasound for Fracture Repair
                                    Advances in Science and Technology 2010 Jan;76195-206
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                                        Biodegradable polyphosphazene-nanohydroxyapatite composite nanofibers: scaffolds for bone tissue engineering.
                                    Journal of biomedical nanotechnology 2009 Feb;5(1):69-75
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                                        Induction of angiogenesis in tissue-engineered scaffolds designed for bone repair: a combined gene therapy-cell transplantation approach.
                                    Proceedings of the National Academy of Sciences of the United States of America 2008 Aug;105(32):11099-104
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                                        Fracture repair with ultrasound: clinical and cell-based evaluation.
                                    The Journal of bone and joint surgery. American volume 2008 Feb;90 Suppl 1138-44
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                                        Tissue engineering of bone: material and matrix considerations.
                                    The Journal of bone and joint surgery. American volume 2008 Feb;90 Suppl 136-42
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                                        Amorphous hydroxyapatite-sintered polymeric scaffolds for bone tissue regeneration: physical characterization studies.
                                    Journal of biomedical materials research. Part A 2008 Jan;84(1):54-62
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                                        Nanophasic hydroxyapatite incorporated biodegradable polyphosphazene nanofibers for bone tissue engineering
                                    J. Biomed. Nanotechnology 2008 Jan;451-7
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                                        Human endothelial cell growth and phenotypic expression on three dimensional poly(lactide-co-glycolide) sintered microsphere scaffolds for bone tissue engineering.
                                    Biotechnology and bioengineering 2007 Dec;98(5):1094-102
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                                        Apatite nano-crystalline surface modification of poly(lactide-co-glycolide) sintered microsphere scaffolds for bone tissue engineering: implications for protein adsorption.
                                    Journal of biomaterials science. Polymer edition 2007 Jan;18(9):1141-52
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                                        In situ synthesized ceramic–polymer composites for bone tissue engineering: bioactivity and degradation studies
                                    Journal of Materials Science 2007 Jan;42(12):4183-4190
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                                        In situ synthesized ceramic-polymer composites for bone tissue engineering: in vitro evaluation and degradation studies
                                    J Materials Science 2007 Jan;42(12):4183-4190
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                                        Translating science from the benchtop to the bedside: What are the barriers between the research laboratory and the clinical setting, and how can we get past them?
                                    AAOS Now 2007 Jan;1(7):45-46
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                                        The ABJS Nicolas Andry Award: Tissue engineering of bone and ligament: a 15-year perspective.
                                    Clinical orthopaedics and related research 2006 Jun;447221-36
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                                        Bone graft substitutes.
                                    Expert review of medical devices 2006 Jan;3(1):49-57
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                                        In Vitro and In Vivo Characterization of Biodegradable Poly(organophosphazenes) for Biomedical Applications
                                    Journal of Inorganic and Organometallic Polymers and Materials 2006 Jan;16(4):365-385
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                                        Tissue-engineered bone formation in vivo using a novel sintered polymeric microsphere matrix.
                                    The Journal of bone and joint surgery. British volume 2004 Nov;86(8):1200-8
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                                        Novel polymer-synthesized ceramic composite-based system for bone repair: an in vitro evaluation.
                                    Journal of biomedical materials research. Part A 2004 Jun;69(4):728-37
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                                        Extracellular matrix production by human osteoblasts cultured on biodegradable polymers applicable for tissue engineering.
                                    Biomaterials 2003 Mar;24(7):1213-21
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                                        Tissue engineered microsphere-based matrices for bone repair: design and evaluation.
                                    Biomaterials 2002 Jan;23(2):551-9
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                                        A novel amorphous calcium phosphate polymer ceramic for bone repair: I. Synthesis and characterization.
                                    Journal of biomedical materials research 2001 May;58(3):295-301
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                                        Bone-graft substitutes: facts, fictions, and applications.
                                    The Journal of bone and joint surgery. American volume 2001 Jan;83-A Suppl 2 Pt 298-103
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                                        Uncoupling of GABA(A) and benzodiazepine receptor binding activity in the hippocampal formation of schizophrenic brain.
                                    Brain research 1997 Apr;755(1):121-9
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                                        Up-regulation of GABAA receptor binding on neurons of the prefrontal cortex in schizophrenic subjects.
                                    Neuroscience 1996 Dec;75(4):1021-31
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                                        Increased interaction of dopamine-immunoreactive varicosities with GABA neurons of rat medial prefrontal cortex occurs during the postweanling period.
                                    Synapse (New York, N.Y.) 1996 Aug;23(4):237-45
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                                        Differences in the subregional and cellular distribution of GABAA receptor binding in the hippocampal formation of schizophrenic brain.
                                    Synapse (New York, N.Y.) 1996 Apr;22(4):338-49
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                                        Cellular colocalization of dopamine D1 and D2 receptors in rat medial prefrontal cortex.
                                    Synapse (New York, N.Y.) 1995 Feb;19(2):112-20
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                                        Myelination of a key relay zone in the hippocampal formation occurs in the human brain during childhood, adolescence, and adulthood.
                                    Archives of general psychiatry 1994 Jun;51(6):477-84
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                                        Cellular distribution of dopamine D1 and D2 receptors in rat medial prefrontal cortex.
                                    The Journal of neuroscience : the official journal of the Society for Neuroscience 1993 Jun;13(6):2551-64
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                                        Ultrasound-derived mechanical stimulation of cell-laden collagen hydrogels for bone repair.
                                    J Biomed Mater Res part A
 
Books
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                                    Regenerative Engineering: Advanced Materials Science Principles 2018 Oct;
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                                    Regenerative Engineering: Advanced Materials Science Principles
 
Book Chapters
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                                        Materials Science and Biodegradable Scaffolds
                                    Orthobiologics 2023 Feb;
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                                        Bone Tissue Engineering
                                    Musculoskeletal Tissue Engineering 2021 May;
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                                        Characterizing the Properties of Tissue Constructs for Regenerative Engineering
                                    Encyclopedia of Biomedical Engineering 2018 Jan;
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                                        Materials Science and Biodegradable Scaffolds
                                    Orthobiologics: Scientific and Clinical Solutions for Orthopaedic Surgeons.
 
Book Sections
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                                        Polyphosphazenes
                                    An Introduction to Biomaterials and Their Applications 2010 Jan;
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                                        Microporous nanofibrous fibrin-based scaffolds for bone tissue engineering.
                                    Biomaterials 2008 Oct;29(30):4091-9
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                                        Polyphosphazenes
                                    Introduction to Biomaterials 2006 Jan;273-290
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                                        Bone Grafts and Bone Graft Substitutes: A Brief History
                                    Bone Graft Substitutes: A Multidisciplinary Perspective 2003 Jan;63-10
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                                        Nanotechnology and Tissue Engineering
                                    NanoComputing-Technology Trends 2001 Jan;
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                                        Processing of Polymer Scaffolds: Polymer/Ceramic Composite Forms
                                    Methods of Tissue Engineering 2001 Jan;705-713
 
Conference Papers
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                                        Biofunctionalizing devitalized bone allografts through polymer-mediated short and long term growth factor delivery.
                                    Journal of biomedical materials research. Part A 2011 Jan;103(9):2847-54
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                                        Fabrication and biocompatibility of polyphosphazene Tubular electrospun nanofiber scaffolds for bone tissue engineering
                                    2006 Jan;
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                                        A Novel Polymer-Synthesized Ceramic Composite Based System for Bone Repair: Osteoblast Growth on Scaffolds With Varied Calcium Phosphate Content
                                    2003 Jan;84563-67
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                                        Toward an International Tissue Engineering Curriculum: The Drexel Initiative
                                    2002 Jan;
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                                        Nanotechnology and Tissue Engineering
                                    2001 Jan;155-162
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                                        Increased GABAA receptor binding in superficial layers of cingulate cortex in schizophrenics.
                                    The Journal of neuroscience : the official journal of the Society for Neuroscience 1993 Jan;12(3):924-9
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                                        Dopamine D1 and D2 Receptors Colocalize to the Same Cells in Rat Medial Prefrontal Cortex
                                    1991 Jan;
 
Letters
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                                        Serological survey of mumps immunity among healthcare workers in Connecticut, December 2006-May 2007.
                                    Infection control and hospital epidemiology 2009 Feb;30(2):202-3
 
Other
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                                        Bone Graft Substitute Materials
                                    Emedicine 2002 Jan;
 
Reviews
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                                        The potential role of mechanotransduction in the management of pediatric calvarial bone flap repair.
                                    Biotechnology and bioengineering 2024 Jan;
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                                        Tissue engineering of bone: a primer for the practicing hand surgeon.
                                    The Journal of hand surgery 2009 Jan;34(1):164-6
 
| Title or Abstract | Type | Sponsor/Event | Date/Year | Location | 
|---|---|---|---|---|
| LIPUS-Derived Mechanical Stimulation of Alginate Hydrogels for Bone Repair: A Regenerative Engineering Approach. | Talk | Society for Biomaterials Annual Meeting | 2019 | Seattle WA | 
| Regenerative Engineering-based Strategies for Bone Repair | Other | Vellore Institute of Technology /2019 Indiana Summit | 2019 | Indianapolis, IN | 
| Regenerative Engineering-based Strategies for Bone Repair | Other | American Ceramic Society | 2019 | Toronto, CA | 
| Acoustic Radiation Force-Derived Mineralization within a Biodegradable Hydrogel Enhances Bone Formation. | Other | Materials Science & Technology Annual Meeting | 2019 | Portland, OR | 
| Dual Growth Factor Delivery from Devitalized Allografts Enhances Healing in a Large Scale Segmental Bone Defect Model. | Other | Materials Science & Technology Annual Meeting | 2018 | Columbus, OH | 
| The Use of Low Intensity Acoustic Radiation Force with Cell-Loaded Hydrogels for Bone Repair | Other | Society for Biomaterials Annual Meeting | 2017 | Denver CO | 
| Acoustic Radiation Force to Mechanically Load Hydrogel-Encapsulated Osteoblasts for Regenerative Engineering-based Bone Repair. | Talk | Society for Biomaterials World Congress | 2016 | Montreal, CA | 
| Growth Factor Delivery from Devitalized Allografts to Enhance Large Scale Bone Defect Repair | Talk | Materials Science & Technology Annual Meeting | 2015 | Columbus, OH | 
| Functionalizing Intact Allografts to Enhance Allograft Remodeling and New Bone Formation | Talk | Society for Biomaterials Annual Meeting | 2014 | Denver CO | 
| Substrate-Guided Stem Cell Behavior | Other | Society for Biomaterials Annual Meeting | 2014 | Denver CO | 
| The Novel Use of 3-Dimensional Tissue Mimetics and Ultrasound to Understand the Role of Mechanical Forces in Both Regenerative and Pathological Conditions. | Other | Materials Science & Technology Annual Meeting | 2014 | Pittsburgh, PA | 
| Biphasic Scaffolds for Bone Repair: Nanofiber-permeated Pore Network for Enhanced Cell Population. | Talk | Society for Biomaterials Annual Meeting | 2013 | Boston, MA | 
| Ultrasound as a Physical Force for Enhanced Scaffold-based Bone Repair | Talk | Society for Biomaterials Annual Meeting | 2013 | Boston, MA | 
| Functionalizing Devitalized Allograft for Large Defect Bone Repair. | Other | Materials Science & Technology Annual Meeting | 2013 | Montreal, CA | 
| Combined AFM and 3-D Optical Microscopy of Cells and Biomaterials | Talk | Materials Science & Technology Annual Meeting | 2012 | |
| Functionalizing Allografts with Polymer-Based Bioactive Coatings | Talk | 2011 Musculoskeletal Transplant Foundation’s | 2011 | Chicago, IL | 
| Biofunctionalizing Devitalized Bone Allografts through Polymer-Mediated Growth Factor Delivery | Talk | Society for Biomaterials Annual Meeting | 2011 | |
| Imparting Physical Load to Synthetic Extracellular Matrices Using Ultrasound | Talk | Society for Biomaterials Annual Meeting | 2011 | |
| Short and Long Term Growth Factor Release from Biofunctionalized Bone Allograft | Talk | Biomedical Engineering and Science Annual Meeting | 2011 | |
| Cellular Displacement from Acoustic Radiation Force: Using Ultrasound to Induce Mechanical Loading | Talk | Biomedical Engineering and Science Annual Meeting | 2011 | |
| Stem Cell Behavior | Talk | Society for Biomaterials Annual Meeting | 2010 | Seattle, WA | 
| Low Intensity Pulsed Ultrasound Increases Wnt Signaling in Mouse Osteoprogenitor Cells | Talk | Orthopaedic Research Society Annual Meeting | 2010 | |
| Scaffold-Directed Stem Cell Behavior: The Effect of Polymer Ceramic Composites on Bone Repair | Talk | Society for Biomaterials Annual Meeting | 2010 | |
| Regenerative Engineering: New Avenues for Tissue Repair | Talk | Beacon Alliance Pfizer Seminar Series | 2009 | |
| Bone Bioengineering | Talk | 2008 Washington Orthopaedic Review | 2008 | Washington DC | 
| Principles of Orthopaedic Bioengineering | Talk | 2008 Washington Orthopaedic Review | 2008 | Washington DC | 
| Novel Bilayered Polymeric Microspheres for Bone Tissue Engineering Applications: Effects of Alginate Coating on Release Kinetics | Talk | Society for Biomaterials Annual Meeting | 2008 | |
| Fracture Repair: Challenges and Opportunities | Talk | Symposium, American Academy of Orthopaedic Surgeons | 2007 | Miami Beach, FL | 
| Bone Bioengineering | Talk | 2007 Washington Orthopaedic Review | 2007 | Washington DC | 
| Principles of Orthopaedic Bioengineering | Talk | 2007 Washington Orthopaedic Review | 2007 | Washington DC | 
| In Vivo Evaluation of Novel Biodegradable Physiological Temperature Setting Composites for Bone Tissue Engineering | Talk | Orthopaedic Research Society | 2006 | |
| A Novel Polymer-Ceramic Composite Scaffold for Bone Tissue Engineering: In Vivo Healing and Mineralization Studies | Talk | Orthopaedic Research Society Annual Meeting | 2006 | |
| Fabrication and Biocompatibility of Polyphosphazene Tubular Electrospun Nanofiber Scaffolds for Bone Tissue | Talk | Engineering Summer Bioengineering Conference | 2006 | |
| In Vitro and In Vivo Evaluation of a Novel Polymer-Ceramic Composite Scaffold for Bone Tissue Engineering | Talk | 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society | 2006 | |
| In Vivo Evaluation of a Polymer/Ceramic Composite Scaffold for Bone Tissue Engineering | Talk | Biomedical Engineering Society Annual Meeting | 2005 | |
| Novel Polymer/Ceramic Composite Microsphere- Based Matrices For Bone Tissue Engineering: Processing Effects on Calcium Phosphate | Talk | Society for Biomaterials Annual Meeting | 2004 | |
| Novel Polymer-Synthesized Ceramic Composite Based System for Bone Repair: Osteoblast Growth on Scaffolds With Varied Calcium Phosphate Content | Talk | Materials Research Society Annual Meeting | 2004 | |
| Novel Polymer/Ceramic Composite Microsphere-Based Matrices for Bone Tissue Engineering: Processing Effects on Calcium Phosphate Composition | Talk | Orthopedic Research Society Annual Meeting | 2003 | |
| Novel Polymer/Ceramic Composite Microsphere-Based Matrices For Bone Tissue Engineering: Effects of Processing On Mechanical Properties | Talk | Society for Biomaterials Annual Meeting | 2003 | |
| A Novel Polymer/Ceramic Scaffold for Bone Tissue Engineering: Biocompatibility and Optimization Studies | Talk | Society for Biomaterials Annual Meeting | 2002 | |
| In Vitro Analysis of a Tissue Engineered Scaffold for Bone Repair | Talk | AIChE 2001 Annual Meeting | 2001 | |
| Bone Graft Substitutes: Fact, Fiction and Science | Other | American Academy of Orthopaedic | 2000 | |
| Trabecular Bone regeneration via delivery of a bone morphogenetic protein in a biomimetic polymer matrix: study in a non-union mode | Talk | Proc. Int'l Symp Contr. Rel. Bioactive Mater | 2000 | |
| Towards an International Tissue Engineering Curriculum: The Drexel Initiative. | Talk | 2002 ASEE Annual Conference and Exposition | 2000 | |
| Bone Graft Substitutes: Fact, Fiction and Science | Other | 1991 |