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Hormone action and liver disease, a complex interplay.
Marino, Luigi; Kim, Adam; Ni, Bin; Celi, Francesco S Hepatology (Baltimore, Md.) 2023 Aug;
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Altered anti-viral immune responses in monocytes in overweight heavy drinkers.
Kim, Adam; Ortega-Ribera, Martí; McMullen, Megan R; Bellar, Annette; Taiwo, Moyinoluwa; Pathak, Vai; Streem, David; Dasarathy, Jaividhya; Welch, Nicole; Dasarathy, Srinivasan; Vachharajani, Vidula; Nagy, Laura E iScience 2023 Jul;26(7):107133
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Macrophage-derived MLKL in alcohol-associated liver disease: Regulation of phagocytosis.
Wu, Xiaoqin; Fan, Xiude; McMullen, Megan R; Miyata, Tatsunori; Kim, Adam; Pathak, Vai; Wu, Jianguo; Day, Le Z; Hardesty, Josiah E; Welch, Nicole; Dasarathy, Jaividhya; Allende, Daniela S; McCullough, Arthur J; Jacobs, Jon M; Rotroff, Daniel M; Dasarathy, Srinivasan; Nagy, Laura E Hepatology (Baltimore, Md.) 2022 Jun;
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Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice.
Helsley, Robert N; Miyata, Tatsunori; Kadam, Anagha; Varadharajan, Venkateshwari; Sangwan, Naseer; Huang, Emily C; Banerjee, Rakhee; Brown, Amanda L; Fung, Kevin K; Massey, William J; Neumann, Chase; Orabi, Danny; Osborn, Lucas J; Schugar, Rebecca C; McMullen, Megan R; Bellar, Annette; Poulsen, Kyle L; Kim, Adam; Pathak, Vai; Mrdjen, Marko; Anderson, James T; Willard, Belinda; McClain, Craig J; Mitchell, Mack; McCullough, Arthur J; Radaeva, Svetlana; Barton, Bruce; Szabo, Gyongyi; Dasarathy, Srinivasan; Garcia-Garcia, Jose Carlos; Rotroff, Daniel M; Allende, Daniela S; Wang, Zeneng; Hazen, Stanley L; Nagy, Laura E; Brown, Jonathan Mark eLife 2022 Jan;11
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Gene Deconvolution Reveals Aberrant Liver Regeneration and Immune Cell Infiltration in Alcohol-Associated Hepatitis.
Kim, Adam; Wu, Xiaoqin; Allende, Daniela S; Nagy, Laura E Hepatology (Baltimore, Md.) 2021 Aug;74(2):987-1002
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Identification of a MicroRNA-E3 Ubiquitin Ligase Regulatory Network for Hepatocyte Death in Alcohol-Associated Hepatitis.
Fan, Xiude; Wu, Jianguo; Poulsen, Kyle L; Kim, Adam; Wu, Xiaoqin; Huang, Emily; Miyata, Tatsunori; Sanz-Garcia, Carlos; Nagy, Laura E Hepatology communications 2021 May;5(5):830-845
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Diagnostic and Prognostic Significance of Complement in Patients With Alcohol-Associated Hepatitis.
Fan, Xiude; McCullough, Rebecca L; Huang, Emily; Bellar, Annette; Kim, Adam; Poulsen, Kyle L; McClain, Craig J; Mitchell, Mack; McCullough, Arthur J; Radaeva, Svetlana; Barton, Bruce; Szabo, Gyongyi; Dasarathy, Srinivasan; Rotroff, Daniel M; Nagy, Laura E Hepatology (Baltimore, Md.) 2021 Mar;73(3):983-997
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Hepatobiliary malignancies have distinct peripheral myeloid-derived suppressor cell signatures and tumor myeloid cell profiles.
Bayik, Defne; Lauko, Adam J; Roversi, Gustavo A; Serbinowski, Emily; Acevedo-Moreno, Lou-Anne; Lanigan, Christopher; Orujov, Mushfig; Lo, Alice; Alban, Tyler J; Kim, Adam; Silver, Daniel J; Nagy, Laura E; Brown, J Mark; Allende, Daniela S; Aucejo, Federico N; Lathia, Justin D Scientific reports 2020 Nov;10(1):18848
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Functionally Diverse Inflammatory Responses in Peripheral and Liver Monocytes in Alcohol-Associated Hepatitis.
Kim, Adam; Bellar, Annette; McMullen, Megan R; Li, Xiaoxia; Nagy, Laura E Hepatology communications 2020 Oct;4(10):1459-1476
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Oxidative stress mediates ethanol-induced skeletal muscle mitochondrial dysfunction and dysregulated protein synthesis and autophagy.
Kumar, Avinash; Davuluri, Gangarao; Welch, Nicole; Kim, Adam; Gangadhariah, Mahesha; Allawy, Allawy; Priyadarshini, Anupama; McMullen, Megan R; Sandlers, Yana; Willard, Belinda; Hoppel, Charles L; Nagy, Laura E; Dasarathy, Srinivasan Free radical biology & medicine 2019 Dec;145284-299
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Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross.
Sá, Juliana M; Kaslow, Sarah R; Moraes Barros, Roberto R; Brazeau, Nicholas F; Parobek, Christian M; Tao, Dingyin; Salzman, Rebecca E; Gibson, Tyler J; Velmurugan, Soundarapandian; Krause, Michael A; Melendez-Muniz, Viviana; Kite, Whitney A; Han, Paul K; Eastman, Richard T; Kim, Adam; Kessler, Evan G; Abebe, Yonas; James, Eric R; Chakravarty, Sumana; Orr-Gonzalez, Sachy; Lambert, Lynn E; Engels, Theresa; Thomas, Marvin L; Fasinu, Pius S; Serre, David; Gwadz, Robert W; Walker, Larry; DeConti, Derrick K; Mu, Jianbing; Bailey, Jeffrey A; Sim, B Kim Lee; Hoffman, Stephen L; Fay, Michael P; Dinglasan, Rhoel R; Juliano, Jonathan J; Wellems, Thomas E Nature communications 2019 Sep;10(1):4300
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Impaired Ribosomal Biogenesis by Noncanonical Degradation of β-Catenin during Hyperammonemia.
Davuluri, Gangarao; Giusto, Michela; Chandel, Rajeev; Welch, Nicole; Alsabbagh, Khaled; Kant, Sashi; Kumar, Avinash; Kim, Adam; Gangadhariah, Mahesha; Ghosh, Prabar K; Tran, Uyen; Krajcik, Daniel M; Vasu, Kommireddy; DiDonato, Anthony J; DiDonato, Joseph A; Willard, Belinda; Monga, Satdarshan P; Wang, Yuxin; Fox, Paul L; Stark, George R; Wessely, Oliver; Esser, Karyn A; Dasarathy, Srinivasan Molecular and cellular biology 2019 Aug;39(16):
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Ethanol sensitizes skeletal muscle to ammonia-induced molecular perturbations.
Kant, Sashi; Davuluri, Gangarao; Alchirazi, Khaled A; Welch, Nicole; Heit, Claire; Kumar, Avinash; Gangadhariah, Mahesha; Kim, Adam; McMullen, Megan R; Willard, Belinda; Luse, Donal S; Nagy, Laura E; Vasiliou, Vasilis; Marini, Anna Maria; Weiner, I David; Dasarathy, Srinivasan The Journal of biological chemistry 2019 May;294(18):7231-7244
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Auxin-Inducible Depletion of the Essentialome Suggests Inhibition of TORC1 by Auxins and Inhibition of Vrg4 by SDZ 90-215, a Natural Antifungal Cyclopeptide.
Snyder, Nathan A; Kim, Adam; Kester, Louis; Gale, Andrew N; Studer, Christian; Hoepfner, Dominic; Roggo, Silvio; Helliwell, Stephen B; Cunningham, Kyle W G3 (Bethesda, Md.) 2019 Mar;9(3):829-840
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Plasmodium vivax transcriptomes reveal stage-specific chloroquine response and differential regulation of male and female gametocytes.
Kim, Adam; Popovici, Jean; Menard, Didier; Serre, David Nature communications 2019 Jan;10(1):371
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miRNAs Involved in M1/M2 Hyperpolarization Are Clustered and Coordinately Expressed in Alcoholic Hepatitis.
Kim, Adam; Saikia, Paramananda; Nagy, Laura E Frontiers in immunology 2019 Jan;101295
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Anaphylatoxin Receptors C3aR and C5aR1 Are Important Factors That Influence the Impact of Ethanol on the Adipose Secretome.
McCullough, Rebecca L; McMullen, Megan R; Poulsen, Kyle L; Kim, Adam; Medof, M Edward; Nagy, Laura E Frontiers in immunology 2018 Jan;92133
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H+ and Pi Byproducts of Glycosylation Affect Ca2+ Homeostasis and Are Retrieved from the Golgi Complex by Homologs of TMEM165 and XPR1.
Snyder, Nathan A; Stefan, Christopher P; Soroudi, Camille T; Kim, Adam; Evangelista, Carlos; Cunningham, Kyle W G3 (Bethesda, Md.) 2017 Dec;7(12):3913-3924
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Characterization of P. vivax blood stage transcriptomes from field isolates reveals similarities among infections and complex gene isoforms.
Kim, Adam; Popovici, Jean; Vantaux, Amélie; Samreth, Reingsey; Bin, Sophalai; Kim, Saorin; Roesch, Camille; Liang, Li; Davies, Huw; Felgner, Philip; Herrera, Sócrates; Arévalo-Herrera, Myriam; Ménard, Didier; Serre, David Scientific reports 2017 Aug;7(1):7761
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A LAPF/phafin1-like protein regulates TORC1 and lysosomal membrane permeabilization in response to endoplasmic reticulum membrane stress.
Kim, Adam; Cunningham, Kyle W Molecular biology of the cell 2015 Dec;26(25):4631-45
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Vacuolar H+-ATPase (V-ATPase) promotes vacuolar membrane permeabilization and nonapoptotic death in stressed yeast.
Kim, Hyemin; Kim, Adam; Cunningham, Kyle W The Journal of biological chemistry 2012 Jun;287(23):19029-39
