Photo of Barbara  Kream, Ph.D.

Barbara Kream, Ph.D.

Associate Dean of the Graduate School, UConn Health
Professor, Department of Medicine, and Genetics and Genome Sciences
Academic Office Location:
UConn Health
263 Farmington Avenue
Farmington, CT 06030-1850
Phone: 860-679-3849
Fax: 860-679-1258

Genetics & Developmental Biology Graduate Program

Skeletal Biology and Regeneration Graduate Program

B.A.Mount Holyoke CollegeChemistry
Ph.D.Yale UniversityMolecular Biophysics and Biochemistry

Post-Graduate Training
PostdoctoralUniversity of Wisconsin Biochemistry
PostdoctoralUConn HealthEndocrinology & Metabolism

Name of Award/HonorAwarding Organization
Carole and Ray Neag Medal of HonorUConn Health
Osborn Biomedical Science Graduate Teaching AwardUConn Health Graduate Student Organization
Gideon A. Rodan Excellence in Mentorship AwardAmerican Society for Bone and Mineral Research
Research Career Development Award (RCDA)National Institutes of Health
Proctor and Gamble Research Award Proctor and Gamble
Research and Development AwardAmerican Diabetes Association
Individual National Research Service Award (NRSA)National Institutes of Health
Student Award of the Connecticut Valley Section American Chemical Society
Phi Beta Kappa Mount Holyoke College
Louisa Stone Stevenson Prize in Chemistry Mount Holyoke College
Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
Editorial Board, Bone Editorial BoardEditorial BoardExternalNational2007
President-Elect, President, Past-President, ASBMR Professional/Scientific OrganizationPresidentExternalNational20062009
MD/PhD Program, UCHC Education CommitteeDirectorUConn HealthUniversity20052011
Program Co-Chair of the 25th annual ASBMR meetingProfessional/Scientific OrganizationCo-ChairExternalNational2003
Scientific Policy Committee, ASBMR Professional/Scientific OrganizationCommittee MemberExternalNational20012004
Publications Committee, ASBMR Professional/Scientific OrganizationCommittee MemberExternalNational19971999
Program Director, Pathogenesis and prevention of osteoporosis, P01AR38933 Professional/Scientific OrganizationDirectorExternalNational19972006
Journal of Cellular BiochemistryEditorial BoardEditorial BoardExternalNational19962015
Charter member, Orthopedics and Musculoskeletal Study Section Study SectionMemberExternalNational19931997
Deputy Editor, JBMR Editorial BoardEditorExternalNational19911995
Journal of Bone and Mineral Research (JBMR) Editorial BoardAssociate EditorExternalNational19861991
American Society for Bone and Mineral Research (ASBMR) Professional/Scientific OrganizationCouncilorExternalNational19851988
The major interest of our laboratory has been to elucidate the mechanisms by which hormones and growth factors regulate bone remodeling in postnatal life, with an emphasis on the development and characterization of transgenic and mutant mouse models. Our current projects include investigating the roles of insulin-like growth factor and glucocorticoids on bone remodeling.

Not accepting students for Lab Rotations at this time

Journal Articles


  • Targeted overexpression of Cox-2 in osteoblasts.
    Choudhary S, Diaz-Doran V, Voznesensky O, Xu M, Adams D, Herschman H, Kamei K, Ishikawa K, Kream B, Raisz L, and Pilbeam C. J Bone Miner Res 2009 Jan;24 ((Suppl 1)):
  • Effects of global or targeted deletion of the EP4 receptor on the response of cultured osteoblasts to prostaglandin E2.
    Raisz LG, Alander CA, Zhan P, Breyer MD, Kream BE, and Pilbeam CC. J Bone Miner Res 2004 Jan;19(S1)S5
  • Involvement of AP-1 and CRE sites in the parathyroid hormone induction of COX-2 promoter activity in osteoblastic MC3T3-E1 cells.
    Chikazu D, Voznesensky O, Tetradis S, Tomita M, Kream B, Pilbeam C. J Bone Miner Res 2000 Jan;15(S1)S497
  • Prostaglandins induce ICER expression in osteoblastic cells and mouse calvariae.
    Ammari Z, Nervina JM, Tetradis S, Pilbeam CC, Kream BE. J Bone Miner Res 1999 Jan;14(S1)S350
  • AP-1 and CRE sites jointly mediate the induction of prostaglandin G/H synthase-2 promoter activity basic fibroblast growth factor in osteoblastic MC3T3-E1 cells.
    Okada Y, Tetradis S, Voznesensky O S, Kream BE, Herschman HR, Hurley MM, Pilbeam CC. J Bone Miner Res 1998 Jan;13(S1)S245
  • Parathyroid hormone induces prostaglandin synthase-2 gene expression in MC3T3-E1 cells.
    Tetradis S, Liu Y, Herschman HR, Pilbeam CC, Kream BE. J Bone Min Res 1995 Jan;10(S1)S280

Conference Papers