Photo of Donald L. Kreutzer, PhD

Donald L. Kreutzer, PhD

Professor of Surgery
Academic Office Location:
Surgery
UConn Health
263 Farmington Avenue
Farmington, CT 06030-3955
Phone: 860-679-2801
Fax: 860-679-2936
Education
DegreeInstitutionMajor
BSColorado State University Microbiology
PhDUniversity of KansasMicrobiology and Biochemistry
General Patholgy and Pharmacology (Medical /Dental School Course)
Mechanisms of Disease (Medical /Dental School Course)
Basic Immunology (Undergraduate Course)

Introductory Immunology (Graduate Course)
Immunopathology (Graduate Course)

Immunochemistry (Graduate Course)

Immunochemistry Lab (Graduate Course)

Cellular Immunology Lab (Graduate Course)

Inflammation Repair and Immunity (Medical School Course)

Molecular Immunology (Graduate Course)

General Pathology (Medical/Dental School Course)

Minority Scholars Program (Medical/Dental School Course)

Immunology Elective (MD/PhD Medical School Course)

Introduction to Biomaterials (Graduate Course)

Oral Microbiology (Dental Resident Course)
Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
Diabetes Technology Society Professional/Scientific OrganizationMemberExternalNational
American Association of Immunologist Professional/Scientific OrganizationMemberExternalNational
American Association of Pathologist Professional/Scientific OrganizationMemberExternalNational
American Society for Microbiology Professional/Scientific OrganizationMemberExternalNational
American Society for Cell Biology Professional/Scientific OrganizationMemberExternalNational
American Thoracic Society Professional/Scientific OrganizationMemberExternalNational
American Lung Association Professional/Scientific OrganizationMemberExternalNational
American Heart Association Professional/Scientific OrganizationMemberExternalNational
New York Academy of ScienceProfessional/Scientific OrganizationMemberExternalState
Association for Research in Vision and Ophthalmology Professional/Scientific OrganizationMemberExternalNational
American Association of University Professors Professional/Scientific OrganizationMemberExternalNational
Society for Biomaterials Professional/Scientific OrganizationMemberExternalNational
Research Interest:Role of cell and tissue reactions (Inflammation and wound healing) in controlling the function of implantable devices and performance of biomaterials in vitro and in vivo.

Immunopathology and molecular mechanisms of inflammation, mediators and regulators of leukocyte chemotaxis, modulation of inflammatory reactions by the vascular endothelium.

Journal Articles

Book Chapters

  • Activation of the Complement and Coagulation-Fibrinolytic Pathways in Secretory Otitis Media
    Carlson, J.R., Jozaki, K., Despins, A., Merrow, M., Flaherty, K., Leonard, G., Tzadik, A., Kennedy, T., and Kreutzer, D.L. Recent Advances in Otitis Media
  • Alcohol and Immune System: Role of Gastric Tissue
    Elgebaly, S.A., Kozol, R.A., and Kreutzer, D.L. Alcohol Immunomodulation and AIDS Proceedings 75-78
  • Analysis of Leukocyte Migration and Chemotaxis
    Ribaudo, R.K., Kreutzer, D.L. Investigation of Cell-Mediated Immunity: Practical Methods in Clinical Immunoloy 116-125
  • Biology of the Chemotactic Factor Inactivator
    Ward, P.A., Kreutzer, D.L., Jones, M., and Brozna, J.P. Clinical Aspects of the Complement System 145-148
  • Characterization of Complement Activation Products in SOM
    Carlson, J.R., Despins, A., Merrow, M., Flaherty, K., Leonard, G., Tzadik, A., Kennedy, T., and Kreutzer, D.L. Proc. Intl. Conf. on Acute and Secretory Otitis Media 225-235
  • Cytokines in Chronic Otitis Media with Effusion
    Yellon, R.F., Leonard, G., Marucha, P.T., Carpenter, R.J., Burleson, J.A., and Kreutzer, D.L. The Eustachian Tube, Clinical Aspects 39-43
  • Effects of Pentoxifylline and Neutrophil Function in Trauma and Protective Effects on Chemotactic Factor-Induced Transcutaneous Hypoxia
    Maderazo, E.G., Maderago, A.B., Mercier, E., Kripas, C., Krause, P.J., and Kreutzer, D.L. Pentoxifylline and Leukocyte Function 75-81
  • In Vitro Detection of Cornea-Derived Leukocytic Chemotactic Factors as Indicators of Corneal Inflammation
    Elgebaly, S.A., Forouhar, F., and Kreutzer, D.L. Alternative Methods in Toxicology 257-268
  • Intracellular Survival of Smooth and Rough Strains of Brucella Abortus
    Robertson, D.C., Riley, L.K., Kreutzer, D.L., and Dreyfus, L.A. Mibrobiology 150-153
  • Mechanisms of Inflammation in Lung Tissue
    Kreutzer, D.L., Desai, U., Douglas, W.H., and Blazka, M.E. Hamster Immune Responses in Infectious and Oncologic Diseases 221-230
  • The Modulation of Leudotaxis by Neutral Proteases and Other Factors from Neutrophils
    Ward, P.A., Kreutzer, D.L., and Senior, R.M. Neutral Proteases of Human Polymorphonuclear Leukocytes 276-282

Abstracts

  • Central Role of Macrophages in Controlling Long Term Continuous Glucose Monitoring in Vivo
    U Klueh, Y. Qiao and DL Kreutzer BMES Hartford Connecticut 2011 Oct;
  • Mast Cells, Macrophages and Continuous Glucose Monitoring in Vivo
    U Klueh, M. Kaur, Y. Qiao and DL Kreutzer Diabetes Techonology Society, 9th Scientific Meeting, San Francisco, CA 2009 Nov;
  • Activation of Human Mononuclear Cells by Porcine Biologic Meshes in Vitro
    S. Orenstein MD, Y. Qiao MD, M. Kaur BS, U. Klueh PhD, Don Kreutzer, Yuri Novitsky 16th Annual NESS Surgical Resident and Fellow Research Presentation Day (New England Surgical Society). Boston, MA 2009 May;
  • Activation of human monocytes by human biologic meshes in vitro.
    S. Orenstein, M. Kaur, U. Klueh PhD, D. Kreutzer, Y. Novitsky Association for Academic Surgery Society of University Surgeons. Academic Surgical Congress, Fort Myers, FL 2009 Feb;
  • Activation of human monocytes by human biologic meshes in vitro.
    S. Orenstein, M. Kaur, U. Klueh, D. Kreutzer, Y. Novitsky CTACSPA (Connecticut Chapter of the American College of Surgeons Professional Association). Waterbury, CT 2008 Oct;
  • Polypeptide Multilayer Nanocoatings for Cell Culture and Implant Devices
    DeRome ME, N. Palath, K. Dave, JS Rudra, S. Bhad, U Klueh, DL Kreutzer, DT Haynie Nanomedicine: Nanotechnology, Biology and Medicine 2007 Dec;3(4):353-354
  • Development and Validation of a Murine Model of Implantable Glucose Sensor in the Type I (Juvenile) Diabetic Mouse.
    Platt K, E. Hubert, DL Kreutzer, U. Klueh Medi2005 BEACON, Hartford Connecticut 2005 Oct;
  • Role of Inflammation in Glucose Sensor Function in Vivo.
    Kaur M, D. Montrose, D. Kreutzer, U. Klueh Medi2005 BEACON, Hartford Connecticut October 2005 2005 Oct;
  • Use of Vascular Endothelial Cell Growth Factor Gene Transfer to Enhance Biosensor Function in Vivo.
    Klueh U, D. Dorsky, D. L. Kreutzer Transactions 2003 Society for Biomaterials. 2003 Jan;
  • Uses Of Collagen Related Peptides and Bacterial Related Peptides To Bind And Orient Fibronectin On Surfaces.
    Klueh U, S. Goralnick, J. D. Bryers, D. L. Kreutzer Transactions 2001 Society for Biomaterials. 2001 Jan;
  • Use of Bacterial Adhesion Related and Collagen Related Peptides to Bind and Orient Fibronectin on Surfaces.
    Klueh U, S. Goralnick, J. D. Bryers, D. L. Kreutzer American Vacuum Society. 47th International Symposium 2000 Oct;
  • Characterization of Ligand (Fibronectin) Orientation Once Tethered to Surfaces by Self-Assembled Monolayers.
    Klueh U, J. D. Bryers, D. L. Kreutzer UWEB Summer Symposium 2000. Seattle, Washington. 2000 Jan;
  • Involvement of B cells in pathogenesis of nonarthritic psoriasis in a Kuwaiti population
    Mahmoud, F. F., Al-Saleh, K. A., Al-Harbi, S. A., Landon, G., El-Naby, H., Mathew, C., Daines, D. D., Burleson, J. A., & Kreutzer, D. FASEB Journal 1997 Jan;11692
  • Deficiency of the chemotactic factor inactivator in human sera with 1 -antitrypsin deficiency.
    Ward, P A; Talamo, R C The Journal of clinical investigation 1973 Feb;52(2):516-9
  • A New In Vitro Method for the Quantitation of Endothelial Cell Migration
    Marucha, P.T., Jozaki, K., Despins, A.W. and Kreutzer, D.L. FASEB
  • A Specific C5 Chemotactic Factor Generating Activity is Present in Normal Hamster Lung Lavage Fluid
    Desai, U., Kreutzer, D.L., Kunkel, S. and Ward, P.A. Am. Rev. Resp. Dis. 12165
  • Acute Lung Inflammation Induced by Complement C5
    Kreutzer, D.L., Desai, U., Dickey, B., Kunkel, S.L., Jack, R. and Ward, P.A. Fed. Proc. 38134
  • Anaphylatoxin Inactivator in Acute Inflammation In Vivo
    Hupp, J.R., Tolabi, B.B. and Kreutzer, D.L. J. Dent. Res 67293
  • Association of Increased PA Inhibitor Activity with Macrohage Maturation in Vitreous Granulomas
    Wang, W-P., Kreutzer, D.L., Wang, E., and O'Rourke, J. Invest. Ophthalmol. Vis. Sci. 3084
  • Biosynthesis of Complement Components by Human Cornea
    Rothman, B., Despins, A., McDonald, P., Taylor, D., O'Rourke, J. and Kreutzer, D. Invest. Ophthalmol. Vis. Sci. 2841
  • C3 Dependent Nature of C5 Activity in Normal Hamster Lung Lavage Fluid
    Desai, U. and Kreutzer, D.L. Fed. Proc. 40794
  • Characterization of C3 and C3a Levels in Human Keratopathies
    Merrow, M., Rothman, B., McDonald, P., Taylor, D., O'Rourke, J., Kennedy, T. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 2674
  • Characterization of Fibrinogen Derived Factors in Human Aqueous Humor
    Ribaudo, R., Monahan, K., McDonald, P., Taylor, D., O'Rourke, J. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 28328
  • Characterization of Lipopoly Saccharides Isolated from Smooth and Rough Strains of Brucella abortus
    Kreutzer, D.L., Buller, C.S. and Robertson, D.C. Abstr. Annu. Meet. Am. Soc. Microbiol. 7418
  • Chemotactic Factor Mediated Acute Pulmonary Inflammation
    Desai, U., Kreutzer, D.L., Jack, R., Kunkel, S.L. and Ward, P.A. Fed. Proc. 38120
  • Corneal Epithelial Cell Migration: A Novel Motility Assay Utilizing Microcarrier Beads.
    Despins, A.W., Elgebaly, S.A., O'Rourke, J. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 29194
  • Correlation of Plasminogen Activator, Macrophage and Fibrinogen Derivative Levels Within Murine Vitreous Granulomas
    O'Rourke, J., Wang, W.P. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 29396
  • Demonstration of the Synthesis of Complement C3 and C5 by Human Alveolar Macrophages
    Scherzer, H.H., Kreutzer, D.L., Varani, J., Desai, U. and Senior, R.M. Am. Rev. Resp. Dis. 12192
  • Effect of Alcide: A New Antimicrobial Compound on Leukocyte Chemotaxis In Vitro
    Douglas, D.M., Russell, J.C., Das, D.K. and Kreutzer, D.L. Fed. Proc. 46(3):978
  • Effect of Human Complement C3a on Guinea Pig Lung and Human Neutrophils
    Glovsky, M.M., Kreutzer, D., Showell, H., Kunkel, S., Goers, J. and Ward, P.A. Fed. Proc. 39(3):2269
  • Effect of Mercuric Chloride (HgC12) on Lewis and BN Rat Peritoneal Macrophages and PMNS
    Kosuda, L., Contrino, J., Kreutzer, D.L., and Bigazzi, P.E. FASEB
  • Effect of Pentoxifylline of Human Neutrophil Function In Vitro
    Jozaki, K., Kristie, J., Krause, P. and Kreutzer, D.L. FASEB
  • Effects of DTH and Energy on Intraocular Plasminogen Activator (PA) and PA Inhibitor Levels in Murine Chronic Uveitis
    Wang, W.P., Wang, E., O'Rourke, J. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 28241
  • Effects of Inflammatory Mediators in the Anterior Chamber
    Rowland, F.N., Donovan, M.J., Lindsay, M., Kreutzer, D.L. and O'Rourke, J. Invest. Ophthalmol. Visual Sci. 22212
  • Elaboration of Complement Components by Primary Cultures and Continuous Lines of Human Type II Pneumocytes
    Kreutzer, D.L., Varani, J., Douglas, W. and Blazka, M.E. Am. Rev. Resp. Dis. 12178
  • Elevation of Serum Chemotactic Factor Inactivator Activity in Cystic Fibrosis
    McCormick, J.R., Kreutzer, D.L., Despins, A.W., Ward, P.A., Ganeshanathan, M. and Polmar, S. Am. Rev. Resp. Dis. 121295
  • Enhanced Visualization of Fibrinogen Derivative Depositions in Granulomatous Eye Inflammation
    O'Rourke, J., Wang, W.P. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 2898
  • Familial Deficiency of Complement C5
    McLean, R.H., Guerra, L., Kreutzer, D., Peterson, P.K., Gold, R., Yunis, E., Bissell, A.R., Lerish, V.D. and Peter, G. Current Chemotheraphy and Infectious Disease 831-832
  • Fibrin Induced Generation of Leukocyte Chemotactic Factors: A Model for Ocular Inflammation
    Ribaudo, R., Herkert, N., O'Rourke, J. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 29396
  • Fibrin: A Mediator of Corneal Endothelial Cell Injury
    Rowland, F., Donovan, M., Gillies, C., O'Rourke, J. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 24196
  • Immune Complexes Stimulate Tissue Factor Production by Human Umbilical Vein Endothelial Cells
    Shanahan, W., Mooney, J., Nelson, R., Kreutzer, D., Edwards, R. and Korn, J. Arthritis Rheum. 29S36
  • In Vitro Suppression of Corneal Endothelial Cell (CEC) Migration Induced by Small Molecular Weight (SMW) Fibrinogen Derived Factors (FDF).
    Kreutzer, D.L., Despins, A., Jozaki, K., Ference, R., Raylor, D. and O'Rourke, J. Invest. Ophthalmol. Vis. Sci. 28328
  • Inflammatory Mediators in Alkali-Burned Corneas Inhibitory Effects of Citric Acid
    Elgebaly, S.A., Downes, R.T., Forouhar, F., O'Rourke, J. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 2735
  • Inflammatory Mediators in Alkali-Burned Corneas: Inhibitory Effects of Citric Acid.
    Elgebaly, S.A., Downes, R.T., Forouhar, F., O'Rourke, J. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 2735
  • Interrelationships Between Serum Chemotactic Factor Inactivator, Alpha-1 Anti Trypsin Deficiency and Pulmonary Emphysema
    Chan-Yeung, M., Lam, S., Abboud, R. and Kreutzer, D. Am. Rev. Resp. Dis. 119297
  • Leukocyte-Mediated Injury to Corneal Epithelium: An In Vitro Corneal Cup Model
    Elgebaly, S.A., Baddour, M., Hashem, M., Gillies, C., Forouhar, F., O'Rourke, J. and Kreutzer, D.L. ARVO
  • Lymphokine Induced Biphasic Changes in Vascular Permeability in Hamster Lungs
    Desai, U., Kreutzer, D.L., Masih, N., Yoshida, T. and Ward, P.A. Am. Rev. Resp. Dis. 12165
  • Lymphokine Mediated Regulation of Complement C3 Production by Human Promyelocytic Leukemia Cell line HL-60
    Bamba, M., Rothman, B.L. and Kreutzer, D.L. Fed. Proc. 44(5):1702
  • Morphologic Study of Leukocyte Mediated Injury to Corneal Endothelium
    Elgebaly, S.A., Gillies, C., O'Rourke, J., Donovan, M. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 24197
  • New In Vitro Models of Corneal Endothelial Cell (CEC) Injury (Integrity) and Motility Utilizing Microcarrier Beads
    Despins, A.W., Jozaki, K., Rothman, B., Marucha, P., Taylor, D., O'Rourke, J. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 28172
  • Pentoxifylline Induced Protection of Neonatal Mice from Staphylococcus Aureus Infection
    Kreutzer, D.L., Krause, P.J., Kristie, J., Jozaki, K., Eisenfeld, L., Herson, V.C. and Maderazo, E.G. FASEB
  • Pentoxyifylline-Induced Protection of Neonatal Mice from Staphylococcus-Aureus Infection
    Kreutzer, D.L., Krause, P.J., Kristie, J., Jozaki, K., Eisenfeld, L., Herson, V.C. and Maderazo, E.G. J. Leuk. Biol. 42(4):429
  • Plasminogen Activator Activities in the Aqueous Humor
    Smalley, D., Fitzgerald, J., O'Rourke, J. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 33(4):1189
  • Possible Role of Human Complement on Lung Damage in Guinea Pigs
    Glovsky, M.M., Kreutzer, D., Goers, J., Kunkel, S. and Ward, P.A. J. Allergy Clin. Immunol. 65(3):218
  • Purification of Human Complements C3 and C5 by Hydrophobic Chromotography
    Kunkel, S.L., Kreutzer, D.L., Goralnick, S. and Ward, P.A. Fed. Proc. 38129
  • Quantitation of Fibrinogen Related Antigen Levels in Aqueous Humor from Diseased Human Eyes
    Rahhal, F., Ribaudo, R., Taylor, D., O'Rourke, J. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 2996
  • Quantitation of Total Tissue Plasminogen Activator in Human Aqueous Humor and Plasma
    Wang, E., Wang, W.P., McDonald, P., Taylor, D., O'Rourke, J. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci 29288
  • Role of Leukocytes and Leukocyte Chemotactic Factors in Eye Inflammation
    Donovan, M.J., Elgebaly, S.A., Gillies, C., Balko, L.B., Lindsay, M., O'Rourke, J. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 24197
  • Role of the Complement C5 Related Activity on Leukocyte Generated Tissue Factor Activity
    Muhlfelder, T., Niemetz, J., Kreutzer, D., Beebe, D. and Ward, P. Fed. Proc. 37(3):54
  • Studies on the Complement Derived Chemotactic Factors for Tumor Cells
    Orr, W., Varani, J., Kreutzer, D., Phan, S., Senior, R. and Ward, P.A. Fed. Proc. 37(3):48
  • Suppression of Anaphylatoxin Inactivator During Cobra Venom Factor Mediated Complement Activation In Vivo
    Tolabi, B.B., Hupp, J. and Kreutzer, D.L. J. Dent. Res. 68228
  • Surfaces of Brucella Abortus and Resistance to Anti Microbial Systems
    Kreutzer, D.L. and Robertson, D.C. Abstr. Annu. Meet. Am. Soc. Microbol. 751
  • Surfactant Associated Complement C3 Dependent Complement C5 Cleaving Activity in Normal Hamster Lungs
    Desai, U. and Kreutzer, D.L. Am. Rev. Resp. Dis. 12348
  • The Characterization of Leukocyte and Lymphocyte Responses to Mycobacterial-Induced Uveitis in Mice
    Wang, W.P., Kreutzer, D.L. and O'Rourke, J. Invest. Ophthalmol. Vis. Sci. 2677
  • The Effect of Fibrinogen-Derived Factors on Polymorphonuclear Leukocyte Function
    Ference, R., Marucha, P. and Kreutzer, D.L. J. Dent. Res. 66171
  • The Role of Enogenous Inhibitors in the Regulation of Aqueous Humor Fibrinolysis
    O'Rourke, J., Moore, M. and Kreutzer, D.L. Invest. Ophthalmol. Vis. Sci. 26102
  • Vitreous Granuloma Levels of Plasminogen Activator and Plasminogen Activator Inhibitors in Murine Chronic Uveitis
    Wang, W.P., Wang, E., O'Rourke, J. and Kreutzer, D.L. Invest. Ophthalmol. Viss Sc. 27112

Conference Papers

Editorials

Letters

Other

  • Antiarthritic profile of BF-389--a novel anti-inflammatory agent with low ulcerogenic liability.
    Wong, S; Lee, S J; Frierson, M R; Proch, J; Miskowski, T A; Rigby, B S; Schmolka, S J; Naismith, R W; Kreutzer, D C; Lindquist, R Agents and actions 1992 Sep;37(1-2):90-8
  • Rapid purification of human immunoglobulin (IgG) by a novel ion-exchange system
    Kreutzer D.L., Nelson R., Hou K. Federation Proceedings 1985 Jan;44(6):
  • Regulation of complement component production by human peripheral blood monocytes
    Bamba M., Rothman B., Kreutzer D.L. Federation Proceedings 1984 Jan;43(6):
  • The effects of D-valine on mammalian cells in long term cell culture
    Picciano P.T., Walenga R.W., Douglas W., Kreutzer D.L. Federation Proceedings 1982 Jan;41(3):
  • Chemotactic factor influences on the aggregation, swelling, and foreign surface adhesiveness of human leukocytes.
    O'Flaherty, J T; Kreutzer, D L; Ward, P A The American journal of pathology 1978 Mar;90(3):537-50
  • Regulatory dysfunction in leukotaxis
    Ward P.A., Johnson K.J., Kreutzer D.L. American Journal of Pathology 1977 Jan;88(3):701-710
  • Artificial Tissue Systems and Uses Thereof (Co-Inventors: Klueh U, Dorsky DI, Kreutzer, DL); Application No.: 13/787188; Filing Date: 03.06.2013; Approved October 7, 2015. Application No.: 13/787188
    Co-Inventors: Klueh U, Dorsky DI, Kreutzer, DL. (2015)
  • Co-Inventors: Klueh U, Kreutzer DL. (2015). Cannulas, Collars for Implantable Devices, and Corresponding Systems and Methods. No. US-2014-0262879-A1
  • Co-Inventors: Klueh U, Kreutzer DL. (2015). Coated Surgical Mesh, and Corresponding Systems and Methods. No. US-2014-0275905-A1
  • Co-Inventors: Klueh U, Kreutzer DL. (2015). Sensors, Sensor Systems and Methods. No. US-2014-0275904-A1
  • Co-Inventors: Klueh, Dorsky, Kreutzer. Uses of Artificial Tissues Containing Genetically Engineered Cells and Cell Support Systems to Enhance the Function of Implanted Materials and Devices (Co-Inventors: Klueh, Dorsky, Kreutzer); Canadian Application No.: 2,544,726. Canadian Patent Application No.: 2,544,726
  • Co-Inventors: Klueh, Dorsky, Kreutzer. Uses of Artificial Tissues Containing Genetically Engineered Cells and Cell Support Systems to Enhance the Function of Implanted Materials and Devices (Co-Inventors: Klueh, Dorsky, Kreutzer); International Application Date: 05.11.2004; European Application No.: 04816945.2. European Patent Application No.: 04816945.2
  • Sensors, Cannulas, Collars and Coated Surgical Mesh, and Corresponding Systems and Methods; Patent Application No. US-20150257865; Filing Date: 09.12.2014. Application No. US-20150257865
    Ulrike Klueh and Donald Kreutzer
Title or AbstractTypeSponsor/EventDate/YearLocation
Critical Role of Macrophage Chemokines in Controlling Continuous Glucose Monitoring (CGM) in VivoTalkDiabetes Techonology Society2012Bethesda, Maryland
Central Role of Macrophages in Controlling Long Term Continuous Glucose Monitoring in VivoTalkBMES2011Hartford, Connecticut
Mast Cells, Macrophages and Continuous Glucose Monitoring in VivoTalkDiabetes Techonology Society2009San Francisco, California
Key Role of Mast Cells in Controlling Glucose Sensor Function in VivoTalkAmerican Diabetes Association2009New Orleans, Louisiana
Activation of Human Mononuclear Cells by Porcine Biologic Meshes in VitroTalkNew England Surgical Society2009Boston, Massachusetts
Activation of Human Monocytes by Human Biologic Meshes In VitroTalkAcademic Surgery Society of University Surgeons2009Fort Myers, Florida
The Artificial Pancreas: Hope and HurtlesTalkAmerican Diabetes Association2009Middletown, Connecticut
Key Role of Mast Cells in Controlling Glucose Sensor Function in VivoTalkAmerican Diabetes Association2009New Orleans, Louisiana
Mast Cells, Macrophages and Continuous Glucose Monitoring in VivoTalkDiabetes Techonology Society2009San Francisco, California
Decreased Expression Of Hepatic Signaling Phosphoproteins After Laparoscopic And Hand-Assisted SurgeryTalkSociety Of American Gastrointestinal And Endoscopic Surgeions 2008Philadelphia, Pennsylvania
Activation of Human Monocytes by Human Biologic Meshes In VitroTalkCTACSPA2008Waterbury, Connecticut
Blood Induced Interference of Glucose Sensor Function in Vitro: Implications for in Vivo Sensor FunctionTalkDiabetes Technology Meeting2006Atlanta, Georgia
Role of Inflammation in Glucose Sensor Function in VivoTalkMedi2005 BEACON2005Hartford, Connecticut
Development and Validation of a Murine Model of Implantable Glucose Sensor in the Type I (Juvenile) Diabetic MouseTalkMedi2005 BEACON2005Hartford, Connecticut
Murine Model of Implantable Glucose Sensors: A Novel Model for Glucose Sensor DevelopmentTalkDiabetes Technology Meeting2005San Francisco, California
Use of Vascular Endothelial Cell Growth Factor Gene Transfer to Enhance Biosensor Function in VivoTalkSociety for Biomaterials2003
Uses Of Collagen Related Peptides and Bacterial Related Peptides To Bind And Orient Fibronectin On SurfacesTalkSociety for Biomaterials2001
Molecular Study of the Intracullar Signaling Pathways of Breast Cancer CellsPosterASCP/CAP 2000San Diego, California
Enhanced Expression of TNF and TNF Receptors in Human Breast CancerPosterASCP/CAP Fall Annual Meeting2000San Diego, California
Characterization of Ligand (Fibronectin) Orientation Once Tethered to Surfaces by Self-Assembled MonolayersTalkUWEB Summer Symposium2000Seattle, Washington
Use of Bacterial Adhesion Related and Collagen Related Peptides to Bind and Orient Fibronectin on SurfacesTalkAmerican Vacuum Society2000
Co-Expression of IL-8 and VEGF in HNSCCATalkEastern Section of the Triological Meeting1998
Expression of Tumor Necrosis Factor (TNF-Alpha and TNF-Beta) and TNF Receptors in Human Breast CarcinomaPosterSociety of Surgical Oncology1998San Diego, California
GRO-Alpha Expression in Human Breast Cancer TissueTalkConnecticut Chapter of the American College of Surgeons 1998Cromwell, Connecticut
Angiogenesis Index and Outcomes of Radical ProstatectomyTalkAmerican Urological Assoc., Inc.1997New Orleans, Louisiana
Expression of Interferon-Gamma in Nasal PolyposisTalkTriological Society Meeting1997
Expression of Transforming Growth Factor-Beta I and II in Middle Ear EffusionsTalkAssociation for Research in Otolaryngology1997St. Petersburg, Florida
Tumor Cell Expression of Interleukin-1 Receptor Type I in Pancreatic AdenocarcinomaPosterSociety of Surgical Oncology Meeting1997Chicago, Illinois
Expression of IL-8 Receptors on Tumor Cells and Vascular Endothelial Cells in Human Breast Cancer TissuePosterSociety of Surgical Oncology Meeting1997Chicago, Illinois
Role of Fibroblast Growth Factor and its Receptors in Head and Neck Squamous Cell CarcinomaTalkSociety of Head and Neck Surgeons1997Cancun, Mexico
Vascular Endothelial Growth Factor (VEGF) Expression and its Receptors (kdr and flt) in Head and Neck Squamous Cell CarcinomaTalkSociety of Head and Neck Surgeons1997Cancun, Mexico
Transforming Growth Factor Beta and TGF-Beta Receptor Expression in a Xenograft Model of Human Head and Neck Squamous Cell CarcinomaTalkSociety of Head and Neck Surgeons1997Cancun, Mexico
Interleukin-8 Receptors (IL 8RA and IL-8RB) in Head and Squamous Cell CarcinomaTalkSociety of Head and Neck Surgeons1997Cancun, Mexico
VEGF Expression in Human Prostate CancerTalkAmerican Urologic Association Meeting1997New Orleans, Louisiana
Angiogenesis Factors in Human Prostate Cancer: Ex Vivo and In Vitro Expression in VEGF and IL-8 in Human Prostate CancerTalkAmerican Urologic Association Meeting1997New Orleans, Louisiana
Elevated Interleukin-8 (IL-8) Levels in the CSF of Severe Head InjuryTalkINTS1997Seoul, Korea
Expression of Interferon-Gamma in Nasal PolyposisTalkAssociation for Research in Otolaryngology1997St. Petersburg, Florida
Interleukin-8 Expression and Human Bladder Cancer: In Situ and In Vitro Expression of IL-8 by Human Bladder Cancer CellsTalkAmerican Urological Assoc., Inc.1997New Orleans, Louisiana
Fibrin Regulation of Angiogenic Factor Expression by Human Breast Cancer Cells In VitroPosterAmerican Association for Cancer Research1996Washington, DC
Decreased Expression of Transforming Growth Factor Beta Receptors in Head and Neck Squamous Cell Carcinoma Tumor CellsTalkIntl. Conference on Head and Neck Cancers1996Toronto, Canada
Angiogenesis and Prostate Cancer: In Vivo and In Vitro Expression of Angiogenesis Factors by Prostate Cancer CellsTalkNew England Section of the American Urologic Association1996Lake George, New York
Increased Angiogenesis Factor Expression is Associated with Negative Hormone Receptor Status in Human Breast CancerTalkAmerican College of Surgeons1996San Francisco, California
Vascular Endothelial Growth Factor Expression in Human Prostate CancerTalkInternational Symposium on Biology of Prostate Growth1996Washington, D.C.
Cytokine Regulation of Angiogenesis Factors in Human Prostate CancerTalkAmerican Urologic Association Meeting1996Orlando, Florida
Interleukin-8 Production by Esophageal Epithelial Cells (HET-1A) in Culture: Response to Acid, Pepsin, and Bile AcidsTalkAmerican Gastroenterological Association 1996
Expression of IL-10 in Nasal PolyposisTalkAssociation for Research in Otolaryngology1996
Cytokine Regulation of Angiogenesis Factor Expression in Human Breast CancerTalkSociety of Surgical Oncology1996Atlanta, Georgia
Expression of Interleukin-8 Receptor A in Pancreatic AdenocarcinomasTalkNew England Cancer Society Meeting1996Hanover, New Hampshire
Angiogenesis in Colon Cancer and Normal Adjacent TissueTalkNew England Cancer Society Meeting1996Hanover, New Hampshire
Fibrin Induction of IL-8 Expression in Human Pancreatic Adenocarcinoma Cells In VitroTalkSociety of Surgical Oncology1995
A. Actinomycetemcomitans-Stimulated T Cells Express Dominance of a Limited Number of TCR V-Beta Regions, Akin to SuperantigensTalkAADR Meeting1995
Dominant Expression of T Cell Receptor V-Beta Regions Among Isolated Gingival T Cells Suggests Local Stimulation by SuperantigensTalkAADR Meeting1995
The Role of Cytokines in the Etiology of Nasal PolypsTalkAssociation for Research in Otolaryngology 1995St. Petersburg Beach, Florida
Eosinophil Activation in Pediatric Reflux Esophagitis: Electron Microscopic FeaturesTalkAmerican Gastroenterological Association1995New Orleans, Louisiana
Eosinophils and Esophagitis in Children: Increased Expression of IL-5 in EsophagitisTalkAmerican Gastroenterological Association 1995New Orleans, Louisiana
Fibrin Induction of Tissue Factor Expression in Human Vascular Endothelial CellsTalkInternational Society on Thrombosis and Haemostasis1995Jerusalem, Israel
Histometric Analysis of Periapical Lesions in an Immune Deficient Murine ModelTalkAmerican Association of Endodontists 1995
Expression of Interleukin-8 in Prostate Cancer and Benign Prostatic HyperplasiaTalkEgyptian Urological Association 1995Cairo, Egypt
Fibrin Regulation of Tissue Factor Expression in Vascular Endothelial CellsTalkAmerican Heart Association1995Anaheim, California
Cytokines and Breast Cancer: Interleukin-8 Localization in Infiltrating Ductal Breast CancerTalkThe Society of Surgical Oncology1994
Cytokines and Nasal PolypsTalkThe American Laryngological, Rhinological and Otological Society Meeting1994Palm Beach, Florida
Eosinophils and IBD Elevation of Local IL-5 Expression in Ulcerative Colitis and Crohn's DiseaseTalkAmerican Gastroenterological Association 1994New Orleans, Louisiana
Role of Interleukin-8 in Neovascularization in Human Breast CancerTalkNew England Cancer Society Meeting1994Springfield, Massachusetts
Lymphocyte Recruitment in Head and Neck Squamous Cell Carcinoma: IL8 Expression by Tumor CellsTalk. American Society Head and Neck Surgery 1993
Induction of the Interleukin-8 Production During Cardiopulmonary Bypass SurgeryTalkInterscience World Conference on Inflammation, Antirheumatics, Analgesics, 1993Geneva, Switzerland
Fibrinopeptide A (FPA) and Fibrinopeptide B (FPB) Induced Tissue Factor and Plasminogen Activator Expression in Human Vascular Endothelial Cells (HUVEC) In VitroTalkInternational Society on Thrombosis and Haemostasis1993New York, New York
Interleukin-8 (Leukocyte Chemotactic Factor) and Chronic Otitis Media with EffusionTalkAssociation for Research in Otolaryngology Meeting1993St. Petersburg, Florida
Detection of IL-1 Beta in Human SemenTalkAmerican Urological Association 1992Washington, D.C.
Cytokine Expression by Head and Neck Squamous Cell Carcinomas (HNSCC)TalkInternational Conference on Head and Neck Cancer1992San Francisco, California
Neutrophil Chemotactic Factors Released from Ischemic Human Hearts: Dissociation of a Small Active Factor from a Large Molecular Weight Co-FactorTalkAmerican College of Surgeons1992San Francisco, California
A Novel Probe for the Analysis of Functional TF Expression In SituTalkClinical Research Society1992Baltimore, Maryland
Characterization of a Novel Small Molecular Weight Neutrophil Chemotactic Factor Released from Ischemic Human HeartsTalkAmerican Heart Association 1992New Orleans, Louisiana
Murine Model of Otitis Media with Effusion (OME): Demonstration of IL1 Alpha ExpressionTalkThe American Larynogological, Rinological and Otological Society, Inc. 1992
Characterization of Phospholipid Metabolites in Human Middle Ear EffusionsTalkAmerican Society of Pediatric Otolaryngology1992Palm Desert, California
Phospholipid Metabolite Expression by Head and Neck Squamous Cell CarcinomaTalkInternational Conference on Head and Neck Cancer1992
Characterization of Phospholipid Metabolites in Human Middle Ear EffusionsTalkRecent Advances in Otitis Media1991Fort Launderdale, Florida
In Vivo Eye Model Responses to Microvascular Endothelial Activation and InjuryTalkAmerican College of Cardiology1991Atlanta, Georgia
A Novel In Vitro Model of Vascular Cell MigrationTalkIntl. Congresses on Inflammation1990Milano, Italy
TNP Stimulation of IL-1 Beta Production in Neonatal and Adult NeutrophilsTalkAmerican Pediatric Society1990Albuquerque, New Mexico
Monokine Regulation of IL1 Beta Gene Expression in the Human Polymorphonuclear LeukocyteTalkSociety for Leukocyte Biology1990Heraklion, Crete, Greece
IL1 Beta Production in Neonatal and Adult Neutrophils Stimulated by CytokinesTalkSociety for Leukocyte Biology1990Heraklion, Crete, Greece
Cornea Derived Neutrophil Chemotactic Factor: Synthesis and ReleaseTalkARVO1989
Cytokines and Chronic Otitis Media with Effusion (COME)TalkConference on the Eustachian Tube and Middle Ear Diseases1989Geneva, Switzerland
Characterization of a Fibronectin Spreading Defective CHO MutantTalkEast Coast Connective Tissue Meeting1989
Cells with Impaired Spreading Properties on FibronectinTalkAmerican Society for Cell Biology1989Houston, Texas
Chemotactic Factors Released by Mechanically Injured Corneal Epithelial CellsTalkInternational Society for Eye Research1986Japan
Characterization of Leukocyte Chemotactic Factors Released by Isolated Corneas in Response to Injury (Chemical vs. Mechanical)TalkCenter for Alternatives to Animal Testing1986Baltimore, Maryland
Characterization of Complement Activation Products in SOMTalkInternational Conference on Acute and Secretory Otitis Media1985Jerusalem, Israel