Faculty Directory › UConn Health

Chia-Ling Kuo, Ph.D.

Senior Biostatistician, Connecticut Convergence Institute for Translation in Regenerative Engineering
Associate Professor, Public Health Sciences

Academic Office Location: UConn Health 195 Farmington Avenue Farmington, CT 06032
Email:	kuo@uchc.edu
Website(s):	Connecticut Convergence Institute
Curriculum Vitae:	View

Overview
Education & Training
Publications

I hold a PhD in biostatistics with special emphasis and expertise in statistical genetics and genetic epidemiology. During my postdoctoral training at the National Institute of Environmental Health Sciences, my research was focused on design and analysis of large-scale genetic association studies. My research interest is primarily in genetic epidemiology of aging. I have a track record of publications and NIH-funded grants as the Principal Investigator (see below).

R21AG060018 (PI: Kuo) 09/01/2018-06/30/2021

NIH/NIA

Understanding the Role of ApoE2 in Longevity and Age-Related Diseases and Conditions Using 500,000 UK Biobank Participants

Role: Principal Investigator

R21AG060018-02S1 (PI: Kuo) 09/01/2020-06/30/2021

NIH/NIA COVID-19 supplement grant

Genetic susceptibility of ApoE to delirium and dementia in COVID-19 confirmed cases

Role: Principal Investigator

R21NR018963-01A1 (PI: Kuo) 09/02/2020-07/31/2022

NIH/NINR

Identifying potentially modifiable exposures to improve telomere health and disease outcomes

Role: Principal Investigator

3R21NR018963-01A1S1 (PI: Kuo) 07/01/2021-06/30/2022

NIH/NINR

Prognostic value of telomere length for Alzheimer's disease and related measures in the UK Biobank chohort

Role: Principal Investigator

Education

Degree	Institution	Major
B.B.A.	National Chengchi University	Statistics
M.S.	National Taiwan University	Biostatistics, Statistical Genetics
Ph.D.	University of Pittsburgh	Biostatistics, Statistical Genetics

Degree

Institution

Major

B.B.A.

National Chengchi University

Statistics

M.S.

National Taiwan University

Biostatistics, Statistical Genetics

Ph.D.

University of Pittsburgh

Biostatistics, Statistical Genetics

Post-Graduate Training

Training	Institution	Specialty
Postdoctoral	National Institute of Environmental Health Sciences (NIEHS)	Research Fellow

Training

Institution

Specialty

Postdoctoral

National Institute of Environmental Health Sciences (NIEHS)

Research Fellow

Awards

Name of Award/Honor	Awarding Organization
Accredited Professional Statistician (2014-present)	American Statistical Association

Name of Award/Honor

Awarding Organization

Accredited Professional Statistician (2014-present)

American Statistical Association

Journal Articles

Biological Aging Predicts Vulnerability to COVID-19 Severity in UK Biobank Participants.
Kuo, Chia-Ling; Pilling, Luke C; Atkins, Janice L; Masoli, Jane A H; Delgado, João; Tignanelli, Christopher; Kuchel, George A; Melzer, David; Beckman, Kenneth B; Levine, Morgan E The journals of gerontology. Series A, Biological sciences and medical sciences 2021 Mar;
The Influence of Age and Facial Expression (Eye Open/Closed) On Maxillary Dental and Gingival Display.
Bidra, Avinash S; Persenaire, Mitchell; Kuo, Chia-Ling Journal of prosthodontics : official journal of the American College of Prosthodontists 2021 Feb;
The effect of the local administration of biological substances on the rate of orthodontic tooth movement: a systematic review of human studies.
Arqub, Sarah Abu; Gandhi, Vaibhav; Iverson, Marissa G; Ahmed, Maram; Kuo, Chia-Ling; Mu, Jinjian; Dutra, Eliane; Uribe, Flavio Progress in orthodontics 2021 Feb;22(1):5
Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.
Jones, Garan; Trajanoska, Katerina; Santanasto, Adam J; Stringa, Najada; Kuo, Chia-Ling; Atkins, Janice L; Lewis, Joshua R; Duong, ThuyVy; Hong, Shengjun; Biggs, Mary L; Luan, Jian'an; Sarnowski, Chloe; Lunetta, Kathryn L; Tanaka, Toshiko; Wojczynski, Mary K; Cvejkus, Ryan; Nethander, Maria; Ghasemi, Sahar; Yang, Jingyun; Zillikens, M Carola; Walter, Stefan; Sicinski, Kamil; Kague, Erika; Ackert-Bicknell, Cheryl L; Arking, Dan E; Windham, B Gwen; Boerwinkle, Eric; Grove, Megan L; Graff, Misa; Spira, Dominik; Demuth, Ilja; van der Velde, Nathalie; de Groot, Lisette C P G M; Psaty, Bruce M; Odden, Michelle C; Fohner, Alison E; Langenberg, Claudia; Wareham, Nicholas J; Bandinelli, Stefania; van Schoor, Natasja M; Huisman, Martijn; Tan, Qihua; Zmuda, Joseph; Mellström, Dan; Karlsson, Magnus; Bennett, David A; Buchman, Aron S; De Jager, Philip L; Uitterlinden, Andre G; Völker, Uwe; Kocher, Thomas; Teumer, Alexander; Rodriguéz-Mañas, Leocadio; García, Francisco J; Carnicero, José A; Herd, Pamela; Bertram, Lars; Ohlsson, Claes; Murabito, Joanne M; Melzer, David; Kuchel, George A; Ferrucci, Luigi; Karasik, David; Rivadeneira, Fernando; Kiel, Douglas P; Pilling, Luke C Nature communications 2021 Jan;12(1):654
Hemochromatosis Mutations, Brain Iron Imaging, and Dementia in the UK Biobank Cohort.
Atkins, Janice L; Pilling, Luke C; Heales, Christine J; Savage, Sharon; Kuo, Chia-Ling; Kuchel, George A; Steffens, David C; Melzer, David Journal of Alzheimer's disease : JAD 2021 Jan;79(3):1203-1211
Smoking cessation and counseling: A mixed methods study of pediatricians and parents.
Simoneau, Tregony; Hollenbach, Jessica P; Langton, Christine R; Kuo, Chia-Ling; Cloutier, Michelle M PloS one 2021 Jan;16(2):e0246231
Long-term effects of mini-screw-assisted rapid palatal expansion on airway.
Mehta, Shivam; Wang, Dennis; Kuo, Chia-Ling; Mu, Jinjian; Vich, Manuel Lagravere; Allareddy, Veerasathpurush; Tadinada, Aditya; Yadav, Sumit The Angle orthodontist 2020 Dec;
Effect of positional errors on the accuracy of cervical vertebrae maturation assessment using CBCT and lateral cephalograms.
Mehta, Shivam; Dresner, Rebecca; Gandhi, Vaibhav; Chen, Po-Jung; Allareddy, Veerasathpurush; Kuo, Chia-Ling; Mu, Jinjian; Yadav, Sumit Journal of the World federation of orthodontists 2020 Dec;9(4):146-154
Association of Hemochromatosis HFE p.C282Y Homozygosity With Hepatic Malignancy.
Atkins, Janice L; Pilling, Luke C; Masoli, Jane A H; Kuo, Chia-Ling; Shearman, Jeremy D; Adams, Paul C; Melzer, David JAMA 2020 Nov;324(20):2048-2057
Evaluation of open bite closure using clear aligners: a retrospective study.
Harris, Kayla; Ojima, Kenji; Dan, Chisato; Upadhyay, Madhur; Alshehri, Abdulrahman; Kuo, Chia-Ling; Mu, Jinjian; Uribe, Flavio; Nanda, Ravindra Progress in orthodontics 2020 Aug;21(1):23
Utility of Smartphone Telemedical Consultations for Peritonsillar Abscess Diagnosis and Triage.
Mallen, Jonathan R; Shah, Manan Udayan; Drake, Ryan; Kreicher, Kathryn; Falcone, Todd; Karter, Nicholas; Schoem, Scott; Grindle, Christopher; Wolfe, Stephen; Kuo, Chia-Ling; Mu, Jinjian; Lotterman, Seth; Bonaiuto, Gregory JAMA otolaryngology-- head & neck surgery 2020 Aug;
Quantifying tinnitus suppression in cochlear implantation using tinnitus interval-limited tracking.
Mallen, Jonathan R; Chiu, Jerlon; Marquis, Hillary; Ottochian, Amanda; Perez, Erin; Kuo, Chia-Ling; Otto, Steve; Ryan, Tessa; Roberts, Daniel S The Laryngoscope 2020 Aug;130(8):2047-2052
Preexisting Comorbidities Predicting COVID-19 and Mortality in the UK Biobank Community Cohort.
Atkins, Janice L; Masoli, Jane A H; Delgado, Joao; Pilling, Luke C; Kuo, Chia-Ling; Kuchel, George A; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Jul;
Biomarkers of orthodontic tooth movement with fixed appliances and vibration appliance therapy: a pilot study.
Reiss, Stacey; Chouinard, Marie Claude; Frias Landa, Dasha; Nanda, Ravindra; Chandhoke, Taranpreet; Sobue, Takanori; Allareddy, Veerasathpurush; Kuo, Chia-Ling; Mu, Jinjian; Uribe, Flavio European journal of orthodontics 2020 Jun;
ApoE e2 and aging-related outcomes in 379,000 UK Biobank participants.
Kuo, Chia-Ling; Pilling, Luke C; Atkins, Janice L; Kuchel, George A; Melzer, David Aging 2020 Jun;12
Opioid Use and Rate of Nicotine Metabolism among Pregnant Smokers.
Oncken, Cheryl; Mead, Erin L; Dornelas, Ellen A; Kuo, Chia-Ling; Sankey, Heather Z; Kranzler, Henry R; Thurlow, Sheila Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2020 May;22(6):1046-1050
Comparison of external apical root resorption with clear aligners and pre-adjusted edgewise appliances in non-extraction cases: a systematic review and meta-analysis.
Gandhi, Vaibhav; Mehta, Shivam; Gauthier, Marissa; Mu, Jijian; Kuo, Chia-Ling; Nanda, Ravindra; Yadav, Sumit European journal of orthodontics 2020 Feb;
Influence of type of radiograph and levels of experience and training on reproducibility of the cervical vertebral maturation method.
Khajah, Anfal; Tadinada, Aditya; Allareddy, Veerasathpurush; Kuo, Chia-Ling; Nanda, Ravindra; Uribe, Flavio American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2020 Feb;157(2):228-239
GRK2 enforces androgen receptor dependence in the prostate and prostate tumors.
Adler, Adam J; Mittal, Payal; Hagymasi, Adam T; Menoret, Antoine; Shen, Chen; Agliano, Federica; Wright, Kyle T; Grady, James J; Kuo, Chia-Ling; Ballesteros, Enrique; Claffey, Kevin P; Vella, Anthony T Oncogene 2020 Jan;
A 16-Year Study on Incidence and Progression of Diseased Sphenoethmoidal (Onodi) Cell.
Huang, Ethan I; Kuo, Chia-Ling; Lee, Li-Wen BioMed research international 2020 Jan;20202410415
An analysis of anterior mandibular anatomy by using cone beam computed tomography: A study of 225 mandibular images.
Wright, Roberta A; Bidra, Avinash S; Kuo, Chia-Ling The Journal of prosthetic dentistry 2019 Oct;
Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants.
Kuo, Chia-Ling; Pilling, Luke C; Kuchel, George A; Ferrucci, Luigi; Melzer, David Aging cell 2019 Aug;e13017
Relationship between Radiographic Misfit and Clinical Outcomes in Immediately Loaded Complete-Arch Fixed Implant-Supported Prostheses in Edentulous Patients.
Slauch, Robert W; Bidra, Avinash S; Wolfinger, Glenn J; Kuo, Chia-Ling Journal of prosthodontics : official journal of the American College of Prosthodontists 2019 Aug;
The Longevity Associated Sh2b3 (LNK) Genetic Variant: Selected Aging Phenotypes in 379,758 Subjects.
Kuo, Chia-Ling; Joaquim, Micaella; Kuchel, George A; Ferrucci, Luigi; Harries, Lorna; Pilling, Luke C; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2019 Aug;
Cornstarch Requirements of the Adult Glycogen Storage Disease Ia Population: A Retrospective Review.
Dahlberg, K R; Ferrecchia, I A; Dambska-Williams, M; Resler, T E; Ross, K M; Butler, G L; Kuo, C L; Ryan, P; Weinstein, D A Journal of inherited metabolic disease 2019 Aug;
A school nurse-led asthma program reduces absences: Evaluation of Easy Breathing for Schools.
Simoneau, Tregony; Langton, Christine R; Kuo, Chia-Ling; Marrero, Jing; Gherlone, Nicole; Cloutier, Michelle M; Hollenbach, Jessica P Academic pediatrics 2019 Jul;
Interaction between Vitamin D and Interleukin 6 on Slow Gait Speed: 6-year Follow-up Data of Older Adults from InCHIANTI.
Kositsawat, Jatupol; Kuo, Chia-Ling; Barry, Lisa; Melzer, David; Bandinelli, Stefania; Ferrucci, Luigi; Wu, Rong; Kuchel, George A The journals of gerontology. Series A, Biological sciences and medical sciences 2019 Jul;
Hair cortisol, perceived stress, and social support in mother-child dyads living in an urban neighborhood.
Hollenbach, Jessica P; Kuo, Chia-Ling; Mu, Jinjian; Gerrard, Meg; Gherlone, Nicole; Sylvester, Franklin; Ojukwu, Mary; Cloutier, Michelle M Stress (Amsterdam, Netherlands) 2019 Apr;1-8
Sarcopenia and variation in the Human Leukocyte Antigen complex.
Jones, Garan; Pilling, Luke C; Kuo, Chia-Ling; Kuchel, George; Ferrucci, Luigi; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2019 Feb;
Hereditary Hemochromatosis Associations with Frailty, Sarcopenia and Chronic Pain: Evidence from 200,975 Older UK Biobank Participants.
Tamosauskaite, Jone; Atkins, Janice L; Pilling, Luke C; Kuo, Chia-Ling; Kuchel, George A; Ferrucci, Luigi; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2019 Feb;74(3):337-342
Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank.
Pilling, Luke C; Tamosauskaite, Jone; Jones, Garan; Wood, Andrew R; Jones, Lindsay; Kuo, Chai-Ling; Kuchel, George A; Ferrucci, Luigi; Melzer, David BMJ (Clinical research ed.) 2019 Jan;364k5222
Analysis of activating GCM2 sequence variants in sporadic parathyroid adenomas
Riccardi A, Aspir T, Shen L, Kuo CL, Brown TC, Korah R, Murtha TD, Bellizzi J, Parham K, Carling T, Costa-Guda J, Arnold A J Clin Endocrinol Metab 2019 Jan;1041948-52
Evaluation of a guideline directed medical therapy titration program in patients with heart failure with reduced ejection fraction.
Balakumaran, Kathir; Patil, Aadhar; Marsh, Shannon; Ingrassia, Joseph; Kuo, Chia-Ling; Jacoby, Daniel Louis; Arora, Sabeena; Soucier, Richard International journal of cardiology. Heart & vasculature 2018 Nov;221-5
Training for Failure: A Simulation Program for Emergency Medicine Residents to Improve Communication Skills in Service Recovery.
Frallicciardi, Alise; Lotterman, Seth; Ledford, Matthew; Prenovitz, Ilana; Meter, Rochelle Van; Kuo, Chia-Ling; Nowicki, Thomas; Fuller, Robert AEM education and training 2018 Oct;2(4):277-287
Outcomes of an early childhood obesity prevention program in a low-income community: a pilot, randomized trial.
Cloutier, M M; Wiley, J F; Kuo, C-L; Cornelius, T; Wang, Z; Gorin, A A Pediatric obesity 2018 Aug;13677-685
Bone Regenerative Engineering Using a Protein Kinase A-Specific Cyclic AMP Analogue Administered for Short Term
Okechukwu Clinton Ifegwu; Guleid Awale; Ho Man Kan; Komal Rajpura; Edward O’Neill; Chia-Ling Kuo; Kevin W.-H. Lo Regenerative Engineering and Translational Medicine 2018 Jul;4(4):206-215
Endoscopic Features of Mucous Cap Polyps: A Way to Predict Serrated Polyps.
Moy Brian T, Forouhar Faripour, Kuo Chia-Ling,Devers, Thomas J Clinical endoscopy 2018 Apr;51368-374
Opioid Prescribing Patterns among Otolaryngologists.
Schwartz, Marissa A; Naples, James G; Kuo, Chia-Ling; Falcone, Todd E Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2018 Feb;158854-859
Which orthodontic appliance is best for oral hygiene? A randomized clinical trial.
Chhibber, Aditya; Agarwal, Sachin; Yadav, Sumit; Kuo, Chia-Ling; Upadhyay, Madhur American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2018 Feb;153(2):175-183
Biodegradable Piezoelectric Force Sensor.
Curry, Eli J; Ke, Kai; Chorsi, Meysam T; Wrobel, Kinga S; Miller, Albert N; Patel, Avi; Kim, Insoo; Feng, Jianlin; Yue, Lixia; Wu, Qian; Kuo, Chia-Ling; Lo, Kevin W-H; Laurencin, Cato T; Ilies, Horea; Purohit, Prashant K; Nguyen, Thanh D Proceedings of the National Academy of Sciences of the United States of America 2018 Jan;115909-914
Unconditional or Conditional Logistic Regression Model for Age-Matched Case-Control Data?
Kuo, Chia-Ling; Duan, Yinghui; Grady, James Frontiers in public health 2018 Jan;657
Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.
Pilling, Luke C; Kuo, Chia-Ling; Sicinski, Kamil; Tamosauskaite, Jone; Kuchel, George A; Harries, Lorna W; Herd, Pamela; Wallace, Robert; Ferrucci, Luigi; Melzer, David Aging 2017 Dec;9(12):2504-2520
Modified Z-palatoplasty with one-layer closure in one-stage multilevel surgery for severe obstructive sleep apnea.
Huang, Ethan I; Kuo, Chia-Ling; Chou, Yu-Ting; Lin, Yu-Ching; Huang, Shu-Yi Auris, nasus, larynx 2017 Oct;45791-795
Racial/Ethnic Disparities in Morbidity and Mortality for Preterm Neonates Admitted to a Tertiary Neonatal Intensive Care Unit.
Townsel, Courtney; Keller, Rebecca; Kuo, Chia-Ling; Campbell, Winston A; Hussain, Naveed Journal of racial and ethnic health disparities 2017 Oct;5867-874
The more you test, the more you find: The smallest P-values become increasingly enriched with real findings as more tests are conducted.
Vsevolozhskaya, Olga A; Kuo, Chia-Ling; Ruiz, Gabriel; Diatchenko, Luda; Zaykin, Dmitri V Genetic epidemiology 2017 Sep;41726-743
Does the Difference in Fascial Closure Technique Affect Post-Operative Pain?
Lyapis, Anna; Ulrich, Amanda; LaMonica, Rachel; Kuo, Chia-Ling; Kaye, Leak; Luciano, Danielle Journal of minimally invasive gynecology 2017 Jul;241190-1194
Differences in Lip Support with and without Labial Flanges in a Maxillary Edentulous Population - Part 3: Unblinded and Discriminatory Subjective Analysis.
Bidra, Avinash S; Nguyen, Viensuong; Manzotti, Anna; Kuo, Chia-Ling Journal of prosthodontics : official journal of the American College of Prosthodontists 2017 May;2722-28
Correlates of Electronic Cigarettes Use Before and During Pregnancy.
Oncken, Cheryl; Ricci, Karen A; Kuo, Chia-Ling; Dornelas, Ellen; Kranzler, Henry R; Sankey, Heather Z Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2017 May;19(5):585-590
Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.
Pilling, Luke C; Atkins, Janice L; Duff, Michael O; Beaumont, Robin N; Jones, Samuel E; Tyrrell, Jessica; Kuo, Chia-Ling; Ruth, Katherine S; Tuke, Marcus A; Yaghootkar, Hanieh; Wood, Andrew R; Murray, Anna; Weedon, Michael N; Harries, Lorna W; Kuchel, George A; Ferrucci, Luigi; Frayling, Timothy M; Melzer, David PloS one 2017 Jan;12(9):e0185083
Ranking question designs and analysis methods
Hoag, Jessica R; Kuo, Chia-Ling Journal of Medical Statistics and Informatics 2016 May;6(4):
Cost Implications for Subsequent Perinatal Outcomes After IVF Stratified by Number of Embryos Transferred: A Five Year Analysis of Vermont Data.
Carpinello, Olivia J; Casson, Peter R; Kuo, Chia-Ling; Raj, Renju S; Sills, E Scott; Jones, Christopher A Applied health economics and health policy 2016 Mar;14387-95
Prospective cohort pilot study of 2-visit CAD/CAM monolithic complete dentures and implant-retained overdentures: Clinical and patient-centered outcomes.
Bidra, Avinash S; Farrell, Kimberly; Burnham, David; Dhingra, Ajay; Taylor, Thomas D; Kuo, Chia-Ling The Journal of prosthetic dentistry 2016 Jan;115578-586.e1
Evaluation of the donor cell contribution in rhBMP-2 mediated bone formation with chitosan thermogels using fluorescent protein reporter mice.
Gohil, Shalini V; Kuo, Chia-Ling; Adams, Douglas J; Maye, Peter; Rowe, David W; Nair, Lakshmi S Journal of biomedical materials research. Part A 2015 Dec;104928-41
Neck recurrence and mortality in esthesioneuroblastoma: Implications for management of the N0 neck.
Naples, James G; Spiro, Jeffrey; Tessema, Belachew; Kuwada, Clinton; Kuo, Chia-Ling; Brown, Seth M The Laryngoscope 2015 Nov;1261373-9
Assessing the Probability that a Finding Is Genuine for Large-Scale Genetic Association Studies.
Kuo, Chia-Ling; Vsevolozhskaya, Olga A; Zaykin, Dmitri V PloS one 2015 Jan;10(5):e0124107
The ranking probability approach and its usage in design and analysis of large-scale studies.
Kuo, Chia-Ling; Zaykin, Dmitri PloS one 2013 Jan;8(12):e83079
Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies.
McKay, Gareth J; Patterson, Chris C; Chakravarthy, Usha; Dasari, Shilpa; Klaver, Caroline C; Vingerling, Johannes R; Ho, Lintje; de Jong, Paulus T V M; Fletcher, Astrid E; Young, Ian S; Seland, Johan H; Rahu, Mati; Soubrane, Gisele; Tomazzoli, Laura; Topouzis, Fotis; Vioque, Jesus; Hingorani, Aroon D; Sofat, Reecha; Dean, Michael; Sawitzke, Julie; Seddon, Johanna M; Peter, Inga; Webster, Andrew R; Moore, Anthony T; Yates, John R W; Cipriani, Valentina; Fritsche, Lars G; Weber, Bernhard H F; Keilhauer, Claudia N; Lotery, Andrew J; Ennis, Sarah; Klein, Michael L; Francis, Peter J; Stambolian, Dwight; Orlin, Anton; Gorin, Michael B; Weeks, Daniel E; Kuo, Chia-Ling; Swaroop, Anand; Othman, Mohammad; Kanda, Atsuhiro; Chen, Wei; Abecasis, Goncalo R; Wright, Alan F; Hayward, Caroline; Baird, Paul N; Guymer, Robyn H; Attia, John; Thakkinstian, Ammarin; Silvestri, Giuliana Human mutation 2011 Dec;32(12):1407-16
Novel rank-based approaches for discovery and replication in genome-wide association studies.
Kuo, Chia-Ling; Zaykin, Dmitri V Genetics 2011 Sep;189(1):329-40
Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people.
McKay, Gareth J; Silvestri, Giuliana; Chakravarthy, Usha; Dasari, Shilpa; Fritsche, Lars G; Weber, Bernhard H; Keilhauer, Claudia N; Klein, Michael L; Francis, Peter J; Klaver, Caroline C; Vingerling, Johannes R; Ho, Lintje; De Jong, Paulus T D V; Dean, Michael; Sawitzke, Julie; Baird, Paul N; Guymer, Robyn H; Stambolian, Dwight; Orlin, Anton; Seddon, Johanna M; Peter, Inga; Wright, Alan F; Hayward, Caroline; Lotery, Andrew J; Ennis, Sarah; Gorin, Michael B; Weeks, Daniel E; Kuo, Chia-Ling; Hingorani, Aroon D; Sofat, Reecha; Cipriani, Valentina; Swaroop, Anand; Othman, Mohammad; Kanda, Atsuhiro; Chen, Wei; Abecasis, Goncalo R; Yates, John R; Webster, Andrew R; Moore, Anthony T; Seland, Johan H; Rahu, Mati; Soubrane, Gisele; Tomazzoli, Laura; Topouzis, Fotis; Vioque, Jesus; Young, Ian S; Fletcher, Astrid E; Patterson, Chris C American journal of epidemiology 2011 Jun;173(12):1357-64
What's the best statistic for a simple test of genetic association in a case-control study?
Kuo, Chia-Ling; Feingold, Eleanor Genetic epidemiology 2010 Apr;34(3):246-53
Robust score statistics for QTL linkage analysis.
Bhattacharjee, Samsiddhi; Kuo, Chia-Ling; Mukhopadhyay, Nandita; Brock, Guy N; Weeks, Daniel E; Feingold, Eleanor American journal of human genetics 2008 Mar;82(3):567-82
Aging changes in bladder HCN are associated with increasing heterogeneity of adrenergic/mucosal influence on detrusor control in the mouse
Cara C Hardy, BS, Iman M Al-Naggar, PhD, Chia-Ling Kuo, PhD, George A Kuchel, MD, Phillip P Smith, MD

Book Chapters

Normal and non-normal data simulations for the evaluation of two-sample location tests
Hoag, Jessica R; Kuo, Chia-Ling Monte Carlo Simulation-Based Statistical Modeling 2017 Feb;
Discovering multilocus associations with complex pain phenotypes
Kuo, Chia-Ling, Diatchenko, Luda; Zaykin, Dmitri V Genetics of Human Pain Perception: Basic to Translational Science 2013 Nov;

Letters

Response to Comment on "ApoE e4e4 genotype and mortality with COVID-19 in UK Biobank" by Kuo et al.
Kuo, Chia-Ling; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Aug;
ApoE e4e4 genotype and mortality with COVID-19 in UK Biobank.
Kuo, Chia-Ling; Pilling, Luke C; Atkins, Janice L; Masoli, Jane A H; Delgado, João; Kuchel, George A; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2020 Jul;
APOE e4 genotype predicts severe COVID-19 in the UK Biobank community cohort.
Kuo, Chia-Ling; Pilling, Luke C; Atkins, Janice L; Masoli, Jane A H; Delgado, João; Kuchel, George A; Melzer, David The journals of gerontology. Series A, Biological sciences and medical sciences 2020 May;

Reviews

Clinical Factors Affecting the Accuracy of Guided Implant Surgery-A Systematic Review and Meta-analysis.
Zhou, Wenjuan; Liu, Zhonghao; Song, Liansheng; Kuo, Chia-Ling; Shafer, David M The journal of evidence-based dental practice 2018 Mar;18(1):28-40
Prevention of complications in glycogen storage disease type Ia with optimization of metabolic control.
Dambska, M; Labrador, E B; Kuo, C L; Weinstein, D A Pediatric diabetes 2017 Jun;18327-331