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Gonadotropin elevation is ootoxic to ovulatory oocytes and inhibits oocyte maturation, and activin decoy receptor ActRIIB:Fc therapeutically restores maturation.
Bernstein, Lori R; Mackenzie, Amelia C L; Chaffin, Charles L; Lee, Se-Jin; Kraemer, Duane C; Merchenthaler, Istvan Reproductive biology and endocrinology : RB&E 2024 May;22(1):52
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Circulating Growth Differentiation Factors 11 and 8, Their Antagonists Follistatin and Follistatin-like-3, and Risk of Heart Failure in Elders.
Kizer, Jorge R; Patel, Sheena; Ganz, Peter; Newman, Anne B; Bhasin, Shalender; Lee, Se-Jin; Cawthon, Peggy M; LeBrasseur, Nathan; Shah, Sanjiv J; Psaty, Bruce M; Tracy, Russell P; Cummings, Steven R The journals of gerontology. Series A, Biological sciences and medical sciences 2023 Aug;
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Evaluation of Associations of Growth Differentiation Factor-11, Growth Differentiation Factor-8 and their Binding Proteins Follistatin and Follistatin-like protein-3 with Measures of Skeletal Muscle Mass, Muscle Strength and Physical Function in Older Adults.
Cawthon, Peggy M; Patel, Sheena; Newman, Anne B; Bhasin, Shalender; Peng, Liming; Tracy, Russell; Kizer, Jorge R; Lee, Se-Jin; Ferrucci, Luigi; Ganz, Peter; LeBrasseur, Nathan K; Cummings, Steve The journals of gerontology. Series A, Biological sciences and medical sciences 2023 Feb;
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Challenges and Future Prospects of Targeting Myostatin/Activin A Signaling to Treat Diseases of Muscle Loss and Metabolic Dysfunction.
Lee, Se-Jin; Bhasin, Shalender; Klickstein, Lloyd; Krishnan, Venkatesh; Rooks, Daniel The journals of gerontology. Series A, Biological sciences and medical sciences 2023 Feb;
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Evaluation of Associations of Growth Differentiation Factor-11, Growth Differentiation Factor-8 and their Binding Proteins Follistatin and Follistatin-like protein-3 with Dementia and Cognition.
Newman, Anne B; Patel, Sheena; Kizer, Jorge; Lee, Se-Jin; Bhasin, Shalinder; Cawthon, Peggy; LeBrasseur, Nathan; Tracy, Russel P; Ganz, Peter; Cummings, Steve The journals of gerontology. Series A, Biological sciences and medical sciences 2023 Jan;
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BMP10 functions independently from BMP9 for the development of a proper arteriovenous network.
Choi, Hyunwoo; Kim, Bo-Gyeong; Kim, Yong Hwan; Lee, Se-Jin; Lee, Young Jae; Oh, S Paul Angiogenesis 2022 Nov;
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Sex-specific role of myostatin signaling in neonatal muscle growth, denervation atrophy, and neuromuscular contractures.
Emmert, Marianne E; Aggarwal, Parul; Shay-Winkler, Kritton; Lee, Se-Jin; Goh, Qingnian; Cornwall, Roger eLife 2022 Oct;11
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Deletion of Gdf15 reduces ER stress-induced beta cell apoptosis and diabetes.
Xu, Guanlan; Chen, Junqin; Jo, Seong Ho; Grayson, Truman B; Ramanadham, Sasanka; Koizumi, Akio; Germain-Lee, Emily L; Lee, Se-Jin; Shalev, Anath Endocrinology 2022 Mar;
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Functional replacement of myostatin with GDF-11 in the germline of mice.
Lee, Se-Jin; Lehar, Adam; Rydzik, Renata; Youngstrom, Daniel W; Bhasin, Shalender; Liu, Yewei; Germain-Lee, Emily L Skeletal muscle 2022 Mar;12(1):7
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Local versus systemic control of bone and skeletal muscle mass by components of the transforming growth factor-β signaling pathway.
Liu, Yewei; Lehar, Adam; Rydzik, Renata; Chandok, Harshpreet; Lee, Yun-Sil; Youngstrom, Daniel W; George, Joshy; Matzuk, Martin M; Germain-Lee, Emily L; Lee, Se-Jin Proceedings of the National Academy of Sciences of the United States of America 2021 Aug;118(33):
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Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis.
Monsivais, Diana; Nagashima, Takashi; Prunskaite-Hyyryläinen, Renata; Nozawa, Kaori; Shimada, Keisuke; Tang, Suni; Hamor, Clark; Agno, Julio E; Chen, Fengju; Masand, Ramya P; Young, Steven L; Creighton, Chad J; DeMayo, Francesco J; Ikawa, Masahito; Lee, Se-Jin; Matzuk, Martin M Nature communications 2021 Jun;12(1):3386
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Targeting the myostatin signaling pathway to treat muscle loss and metabolic dysfunction.
Lee, Se-Jin The Journal of clinical investigation 2021 May;131(9):
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Functional redundancy of type I and type II receptors in the regulation of skeletal muscle growth by myostatin and activin A.
Lee, Se-Jin; Lehar, Adam; Liu, Yewei; Ly, Chi Hai; Pham, Quynh-Mai; Michaud, Michael; Rydzik, Renata; Youngstrom, Daniel W; Shen, Michael M; Kaartinen, Vesa; Germain-Lee, Emily L; Rando, Thomas A Proceedings of the National Academy of Sciences of the United States of America 2020 Dec;117(49):30907-30917
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Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight.
Lee, Se-Jin; Lehar, Adam; Meir, Jessica U; Koch, Christina; Morgan, Andrew; Warren, Lara E; Rydzik, Renata; Youngstrom, Daniel W; Chandok, Harshpreet; George, Joshy; Gogain, Joseph; Michaud, Michael; Stoklasek, Thomas A; Liu, Yewei; Germain-Lee, Emily L Proceedings of the National Academy of Sciences of the United States of America 2020 Sep;117(38):23942-23951
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Myostatin inhibition promotes fast fibre hypertrophy but causes loss of AMP-activated protein kinase signalling and poor exercise tolerance in a model of limb-girdle muscular dystrophy R1/2A.
Kramerova, Irina; Marinov, Masha; Owens, Jane; Lee, Se-Jin; Becerra, Diana; Spencer, Melissa J The Journal of physiology 2020 Sep;598(18):3927-3939
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Murine FSH production depends on the activin type II receptors ACVR2A and ACVR2B.
Schang, Gauthier; Ongaro, Luisina; Schultz, Hailey; Wang, Ying; Zhou, Xiang; Brûlé, Emilie; Boehm, Ulrich; Lee, Se-Jin; Bernard, Daniel J Endocrinology 2020 Apr;
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Precise Spatiotemporal Control of Nodal Na+ Channel Clustering by Bone Morphogenetic Protein-1/Tolloid-like Proteinases.
Eshed-Eisenbach, Yael; Devaux, Jerome; Vainshtein, Anna; Golani, Ofra; Lee, Se-Jin; Feinberg, Konstantin; Sukhanov, Natasha; Greenspan, Daniel S; Susuki, Keiichiro; Rasband, Matthew N; Peles, Elior Neuron 2020 Mar;
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GDF11 promotes osteogenesis as opposed to MSTN, and follistatin, a MSTN/GDF11 inhibitor, increases muscle mass but weakens bone.
Suh, Joonho; Kim, Na-Kyung; Lee, Seung-Hoon; Eom, Je-Hyun; Lee, Youngkyun; Park, Joo-Cheol; Woo, Kyung Mi; Baek, Jeong-Hwa; Kim, Jung-Eun; Ryoo, Hyun-Mo; Lee, Se-Jin; Lee, Yun-Sil Proceedings of the National Academy of Sciences of the United States of America 2020 Mar;117(9):4910-4920
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Growth differentiation factor 11 locally controls anterior-posterior patterning of the axial skeleton.
Suh, Joonho; Eom, Je-Hyun; Kim, Na-Kyung; Woo, Kyung Mi; Baek, Jeong-Hwa; Ryoo, Hyun-Mo; Lee, Se-Jin; Lee, Yun-Sil Journal of cellular physiology 2019 Jun;
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Myonuclear accretion is a determinant of exercise-induced remodeling in skeletal muscle.
Goh, Qingnian; Song, Taejeong; Petrany, Michael J; Cramer, Alyssa Aw; Sun, Chengyi; Sadayappan, Sakthivel; Lee, Se-Jin; Millay, Douglas P eLife 2019 Apr;8
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Activin type II receptor signaling in cardiac aging and heart failure.
Roh, Jason D; Hobson, Ryan; Chaudhari, Vinita; Quintero, Pablo; Yeri, Ashish; Benson, Mark; Xiao, Chunyang; Zlotoff, Daniel; Bezzerides, Vassilios; Houstis, Nicholas; Platt, Colin; Damilano, Federico; Lindman, Brian R; Elmariah, Sammy; Biersmith, Michael; Lee, Se-Jin; Seidman, Christine E; Seidman, Jonathan G; Gerszten, Robert E; Lach-Trifilieff, Estelle; Glass, David J; Rosenzweig, Anthony Science translational medicine 2019 Mar;11(482):
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Bone morphogenetic protein 9 as a key regulator of liver progenitor cells in DDC-induced cholestatic liver injury.
Addante, Annalisa; Roncero, Cesáreo; Almalé, Laura; Lazcanoiturburu, Nerea; García-Álvaro, María; Fernández, Margarita; Sanz, Julián; Hammad, Seddik; Nwosu, Zeribe C; Lee, Se-Jin; Fabregat, Isabel; Dooley, Steven; Ten Dijke, Peter; Herrera, Blanca; Sánchez, Aránzazu Liver international : official journal of the International Association for the Study of the Liver 2018 Sep;38(9):1664-1675
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Metabolic profiling of follistatin overexpression: a novel therapeutic strategy for metabolic diseases.
Singh, Rajan; Pervin, Shehla; Lee, Se-Jin; Kuo, Alan; Grijalva, Victor; David, John; Vergnes, Laurent; Reddy, Srinivasa T Diabetes, metabolic syndrome and obesity : targets and therapy 2018 Jan;1165-84
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Activin Receptor Type A 2(ACVR2A) Functions Directly in Osteoblasts as a Negative Regulator of Bone Mass.
Goh, Brian C; Singhal, Vandana; Herrera, Angelica J; Tomlinson, Ryan E; Kim, Soohyun; Faugere, Marie-Claude; Germain-Lee, Emily L; Clemens, Thomas L; Lee, Se-Jin; DiGirolamo, Douglas J The Journal of Biological Chemistry 2017 Jun;292(33):13809-13822
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Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
Chung, Hyo Kyun; Ryu, Dongryeol; Kim, Koon Soon; Chang, Joon Young; Kim, Yong Kyung; Yi, Hyon-Seung; Kang, Seul Gi; Choi, Min Jeong; Lee, Seong Eun; Jung, Saet-Byel; Ryu, Min Jeong; Kim, Soung Jung; Kweon, Gi Ryang; Kim, Hail; Hwang, Jung Hwan; Lee, Chul-Ho; Lee, Se-Jin; Wall, Christopher E; Downes, Michael; Evans, Ronald M; Auwerx, Johan; Shong, Minho The Journal of cell biology 2017 Jan;216(1):149-165
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Compound genetically engineered mouse models of cancer reveal dual targeting of ALK1 and endoglin as a synergistic opportunity to impinge on angiogenic TGF-β signaling.
Eleftheriou, Nikolas M; Sjölund, Jonas; Bocci, Matteo; Cortez, Eliane; Lee, Se-Jin; Cunha, Sara I; Pietras, Kristian Oncotarget 2016 Dec;7(51):84314-84325
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BMP1-like proteinases are essential to the structure and wound healing of skin.
Muir, Alison M; Massoudi, Dawiyat; Nguyen, Ngon; Keene, Douglas R; Lee, Se-Jin; Birk, David E; Davidson, Jeffrey M; Marinkovich, M Peter; Greenspan, Daniel S Matrix biology : journal of the International Society for Matrix Biology 2016 Dec;56114-131
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TGFβ1-Mediated SMAD3 Enhances PD-1 Expression on Antigen-Specific T Cells in Cancer.
Park, Benjamin V; Freeman, Zachary T; Ghasemzadeh, Ali; Chattergoon, Michael A; Rutebemberwa, Alleluiah; Steigner, Jordana; Winter, Matthew E; Huynh, Thanh V; Sebald, Suzanne M; Lee, Se-Jin; Pan, Fan; Pardoll, Drew M; Cox, Andrea L Cancer discovery 2016 Dec;6(12):1366-1381
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Paracrine and endocrine modes of myostatin action.
Lee, Yun-Sil; Huynh, Thanh V; Lee, Se-Jin Journal of applied physiology (Bethesda, Md. : 1985) 2016 Mar;120(6):592-8
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Activin Decoy Receptor ActRIIB:Fc Lowers FSH and Therapeutically Restores Oocyte Yield, Prevents Oocyte Chromosome Misalignments and Spindle Aberrations, and Increases Fertility in Midlife Female SAMP8 Mice.
Bernstein, Lori R; Mackenzie, Amelia C L; Lee, Se-Jin; Chaffin, Charles L; Merchenthaler, István Endocrinology 2016 Mar;157(3):1234-47
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Muscle hypertrophy induced by myostatin inhibition accelerates degeneration in dysferlinopathy.
Lee, Yun-Sil; Lehar, Adam; Sebald, Suzanne; Liu, Min; Swaggart, Kayleigh A; Talbot, C Conover; Pytel, Peter; Barton, Elisabeth R; McNally, Elizabeth M; Lee, Se-Jin Human molecular genetics 2015 Oct;24(20):5711-9
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Alternative binding modes identified for growth and differentiation factor-associated serum protein (GASP) family antagonism of myostatin.
Walker, Ryan G; Angerman, Elizabeth B; Kattamuri, Chandramohan; Lee, Yun-Sil; Lee, Se-Jin; Thompson, Thomas B The Journal of biological chemistry 2015 Mar;290(12):7506-16
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Administration of soluble activin receptor 2B increases bone and muscle mass in a mouse model of osteogenesis imperfecta.
DiGirolamo, Douglas J; Singhal, Vandana; Chang, Xiaoli; Lee, Se-Jin; Germain-Lee, Emily L Bone research 2015 Jan;314042
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Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice.
Muir, Alison M; Ren, Yinshi; Butz, Delana Hopkins; Davis, Nicholas A; Blank, Robert D; Birk, David E; Lee, Se-Jin; Rowe, David; Feng, Jian Q; Greenspan, Daniel S Human molecular genetics 2014 Jun;23(12):3085-101
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Denervation atrophy is independent from Akt and mTOR activation and is not rescued by myostatin inhibition.
MacDonald, Elizabeth M; Andres-Mateos, Eva; Mejias, Rebeca; Simmers, Jessica L; Mi, Ruifa; Park, Jae-Sung; Ying, Stephanie; Hoke, Ahmet; Lee, Se-Jin; Cohn, Ronald D Disease models & mechanisms 2014 Apr;7(4):471-81
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Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression.
Yoshimatsu, Yasuhiro; Lee, Yulia G; Akatsu, Yuichi; Taguchi, Luna; Suzuki, Hiroshi I; Cunha, Sara I; Maruyama, Kazuichi; Suzuki, Yuka; Yamazaki, Tomoko; Katsura, Akihiro; Oh, S Paul; Zimmers, Teresa A; Lee, Se-Jin; Pietras, Kristian; Koh, Gou Young; Miyazono, Kohei; Watabe, Tetsuro Proceedings of the National Academy of Sciences of the United States of America 2013 Nov;110(47):18940-5
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Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2.
Lee, Yun-Sil; Lee, Se-Jin Proceedings of the National Academy of Sciences of the United States of America 2013 Sep;110(39):E3713-22
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Bone morphogenetic protein 9 (BMP9) controls lymphatic vessel maturation and valve formation.
Levet, Sandrine; Ciais, Delphine; Merdzhanova, Galina; Mallet, Christine; Zimmers, Teresa A; Lee, Se-Jin; Navarro, Fabrice P; Texier, Isabelle; Feige, Jean-Jacques; Bailly, Sabine; Vittet, Daniel Blood 2013 Jul;122(4):598-607
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Zfp423/OAZ mutation reveals the importance of Olf/EBF transcription activity in olfactory neuronal maturation.
Roby, Yang A; Bushey, Michael A; Cheng, Li E; Kulaga, Heather M; Lee, Se-Jin; Reed, Randall R The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Oct;32(40):13679-88a
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Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway.
Lee, Se-Jin; Huynh, Thanh V; Lee, Yun-Sil; Sebald, Suzanne M; Wilcox-Adelman, Sarah A; Iwamori, Naoki; Lepper, Christoph; Matzuk, Martin M; Fan, Chen-Ming Proceedings of the National Academy of Sciences of the United States of America 2012 Aug;109(35):E2353-60
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BMP9 and BMP10 are critical for postnatal retinal vascular remodeling.
Ricard, Nicolas; Ciais, Delphine; Levet, Sandrine; Subileau, Mariela; Mallet, Christine; Zimmers, Teresa A; Lee, Se-Jin; Bidart, Marie; Feige, Jean-Jacques; Bailly, Sabine Blood 2012 Jun;119(25):6162-71
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Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP.
Liu-Chittenden, Yi; Huang, Bo; Shim, Joong Sup; Chen, Qian; Lee, Se-Jin; Anders, Robert A; Liu, Jun O; Pan, Duojia Genes & development 2012 Jun;26(12):1300-5
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Administration of a soluble activin type IIB receptor promotes the transplantation of human myoblasts in dystrophic mice.
Fakhfakh, Raouia; Lee, Se-Jin; Tremblay, Jacques P Cell transplantation 2012 Jan;21(7):1419-30
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Cardiac myocyte-specific ablation of follistatin-like 3 attenuates stress-induced myocardial hypertrophy.
Shimano, Masayuki; Ouchi, Noriyuki; Nakamura, Kazuto; Oshima, Yuichi; Higuchi, Akiko; Pimentel, David R; Panse, Kalyani D; Lara-Pezzi, Enrique; Lee, Se-Jin; Sam, Flora; Walsh, Kenneth The Journal of biological chemistry 2011 Mar;286(11):9840-8
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Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis.
de Jager, Saskia C A; Bermúdez, Beatriz; Bot, Ilze; Koenen, Rory R; Bot, Martine; Kavelaars, Annemieke; de Waard, Vivian; Heijnen, Cobi J; Muriana, Francisco J G; Weber, Christian; van Berkel, Theo J C; Kuiper, Johan; Lee, Se-Jin; Abia, Rocio; Biessen, Erik A L The Journal of experimental medicine 2011 Feb;208(2):217-25
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Treating cancer cachexia to treat cancer.
Lee, Se-Jin; Glass, David J Skeletal muscle 2011 Jan;1(1):2
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Activin IIB receptor blockade attenuates dystrophic pathology in a mouse model of Duchenne muscular dystrophy.
Morine, Kevin J; Bish, Lawrence T; Selsby, Joshua T; Gazzara, Jeffery A; Pendrak, Klara; Sleeper, Meg M; Barton, Elisabeth R; Lee, Se-Jin; Sweeney, H Lee Muscle & nerve 2010 Nov;42(5):722-30
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Growth differentiation factor 11 signaling controls retinoic acid activity for axial vertebral development.
Lee, Young Jae; McPherron, Alexandra; Choe, Susan; Sakai, Yasuo; Chandraratna, Roshantha A; Lee, Se-Jin; Oh, S Paul Developmental biology 2010 Nov;347(1):195-203
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Regulation of muscle mass by follistatin and activins.
Lee, Se-Jin; Lee, Yun-Sil; Zimmers, Teresa A; Soleimani, Arshia; Matzuk, Martin M; Tsuchida, Kunihiro; Cohn, Ronald D; Barton, Elisabeth R Molecular endocrinology (Baltimore, Md.) 2010 Oct;24(10):1998-2008
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Speed and endurance: you can have it all.
Lee, Se-Jin Journal of applied physiology (Bethesda, Md. : 1985) 2010 Sep;109(3):621-2
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Extracellular Regulation of Myostatin: A Molecular Rheostat for Muscle Mass.
Lee, Se-Jin Immunology, endocrine & metabolic agents in medicinal chemistry 2010 Jan;10183-194
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Activin A and follistatin-like 3 determine the susceptibility of heart to ischemic injury.
Oshima, Yuichi; Ouchi, Noriyuki; Shimano, Masayuki; Pimentel, David R; Papanicolaou, Kyriakos N; Panse, Kalyani D; Tsuchida, Kunihiro; Lara-Pezzi, Enrique; Lee, Se-Jin; Walsh, Kenneth Circulation 2009 Oct;120(16):1606-15
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Redundancy of myostatin and growth/differentiation factor 11 function.
McPherron, Alexandra C; Huynh, Thanh V; Lee, Se-Jin BMC developmental biology 2009 Mar;924
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Genetic analysis of the role of proteolysis in the activation of latent myostatin.
Lee, Se-Jin PloS one 2008 Feb;3(2):e1628
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Sprinting without myostatin: a genetic determinant of athletic prowess.
Lee, Se-Jin Trends in genetics : TIG 2007 Oct;23(10):475-7
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Quadrupling muscle mass in mice by targeting TGF-beta signaling pathways.
Lee, Se-Jin PloS one 2007 Aug;2(8):e789
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Regulation of muscle growth by multiple ligands signaling through activin type II receptors.
Lee, Se-Jin; Reed, Lori A; Davies, Monique V; Girgenrath, Stefan; Goad, Mary E P; Tomkinson, Kathy N; Wright, Jill F; Barker, Christopher; Ehrmantraut, Gregory; Holmstrom, James; Trowell, Betty; Gertz, Barry; Jiang, Man-Shiow; Sebald, Suzanne M; Matzuk, Martin; Li, En; Liang, Li-Fang; Quattlebaum, Edwin; Stotish, Ronald L; Wolfman, Neil M Proceedings of the National Academy of Sciences of the United States of America 2005 Dec;102(50):18117-22
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Myostatin mutation associated with gross muscle hypertrophy in a child.
Schuelke, Markus; Wagner, Kathryn R; Stolz, Leslie E; Hübner, Christoph; Riebel, Thomas; Kömen, Wolfgang; Braun, Thomas; Tobin, James F; Lee, Se-Jin The New England journal of medicine 2004 Jun;350(26):2682-8
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Regulation of muscle mass by myostatin.
Lee, Se-Jin Annual review of cell and developmental biology 2004 Jan;2061-86
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Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases.
Wolfman, Neil M; McPherron, Alexandra C; Pappano, William N; Davies, Monique V; Song, Kening; Tomkinson, Kathleen N; Wright, Jill F; Zhao, Liz; Sebald, Suzanne M; Greenspan, Daniel S; Lee, Se-Jin Proceedings of the National Academy of Sciences of the United States of America 2003 Dec;100(26):15842-6
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Regulation of metanephric kidney development by growth/differentiation factor 11.
Esquela, Aurora F; Lee, Se-Jin Developmental biology 2003 May;257(2):356-70
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Loss of myostatin attenuates severity of muscular dystrophy in mdx mice.
Wagner, Kathryn R; McPherron, Alexandra C; Winik, Nicole; Lee, Se-Jin Annals of neurology 2002 Dec;52(6):832-6
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Induction of cachexia in mice by systemically administered myostatin.
Zimmers, Teresa A; Davies, Monique V; Koniaris, Leonidas G; Haynes, Paul; Esquela, Aurora F; Tomkinson, Kathy N; McPherron, Alexandra C; Wolfman, Neil M; Lee, Se-Jin Science (New York, N.Y.) 2002 May;296(5572):1486-8
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Suppression of body fat accumulation in myostatin-deficient mice.
McPherron, Alexandra C; Lee, Se-Jin The Journal of clinical investigation 2002 Mar;109(5):595-601
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Regulation of myostatin activity and muscle growth.
Lee, S J; McPherron, A C Proceedings of the National Academy of Sciences of the United States of America 2001 Jul;98(16):9306-11
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Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injury.
Hsiao, E C; Koniaris, L G; Zimmers-Koniaris, T; Sebald, S M; Huynh, T V; Lee, S J Molecular and cellular biology 2000 May;20(10):3742-51
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Regulation of left-right patterning in mice by growth/differentiation factor-1.
Rankin, C T; Bunton, T; Lawler, A M; Lee, S J Nature genetics 2000 Mar;24(3):262-5
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Myostatin and the control of skeletal muscle mass.
Lee, S J; McPherron, A C Current opinion in genetics & development 1999 Oct;9(5):604-7
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Characterization of GDF-10 expression patterns and null mice.
Zhao, R; Lawler, A M; Lee, S J Developmental biology 1999 Aug;212(1):68-79
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Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11.
McPherron, A C; Lawler, A M; Lee, S J Nature genetics 1999 Jul;22(3):260-4
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Double muscling in cattle due to mutations in the myostatin gene.
McPherron, A C; Lee, S J Proceedings of the National Academy of Sciences of the United States of America 1997 Nov;94(23):12457-61
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Transient down-regulation of inhibin-betaC expression following partial hepatectomy.
Esquela, A F; Zimmers, T A; Koniaris, L G; Sitzmann, J V; Lee, S J Biochemical and biophysical research communications 1997 Jun;235(3):553-6
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Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member.
McPherron, A C; Lawler, A M; Lee, S J Nature 1997 May;387(6628):83-90
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Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3.
Cunningham, N S; Jenkins, N A; Gilbert, D J; Copeland, N G; Reddi, A H; Lee, S J Growth factors (Chur, Switzerland) 1995 Jan;12(2):99-109
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Oocyte-specific expression of growth/differentiation factor-9.
McGrath, S A; Esquela, A F; Lee, S J Molecular endocrinology (Baltimore, Md.) 1995 Jan;9(1):131-6
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Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily.
Storm, E E; Huynh, T V; Copeland, N G; Jenkins, N A; Kingsley, D M; Lee, S J Nature 1994 Apr;368(6472):639-43
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GDF-3 and GDF-9: two new members of the transforming growth factor-beta superfamily containing a novel pattern of cysteines.
McPherron, A C; Lee, S J The Journal of biological chemistry 1993 Feb;268(5):3444-9
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Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure.
Lee, S J Proceedings of the National Academy of Sciences of the United States of America 1991 May;88(10):4250-4
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Identification of a novel member (GDF-1) of the transforming growth factor-beta superfamily.
Lee, S J Molecular endocrinology (Baltimore, Md.) 1990 Jul;4(7):1034-40
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Expression of HSP86 in male germ cells.
Lee, S J Molecular and cellular biology 1990 Jun;10(6):3239-42
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Trophoblastic giant cells of the mouse placenta as the site of proliferin synthesis.
Lee, S J; Talamantes, F; Wilder, E; Linzer, D I; Nathans, D Endocrinology 1988 May;122(5):1761-8
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Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors.
Lee, S J; Nathans, D The Journal of biological chemistry 1988 Mar;263(7):3521-7
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Secretion of proliferin.
Lee, S J; Nathans, D Endocrinology 1987 Jan;120(1):208-13
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Identification of proliferin mRNA and protein in mouse placenta.
Linzer, D I; Lee, S J; Ogren, L; Talamantes, F; Nathans, D Proceedings of the National Academy of Sciences of the United States of America 1985 Jul;82(13):4356-9