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Targeting AKR1B10 by drug repurposing with epalrestat overcomes chemoresistance in non-small cell lung cancer patient-derived tumor organoids
Kanve N Suvilesh; Yariswamy Manjunath, Yulia I Nussbaum, Mohamed Gadelkarim, Murugesan Raju, Akhil Srivastava, Guangfu Li, Wesley C Warren, Chi-Ren Shyu, Feng Gao, Matthew A Ciorba, Jonathan B Mitchem, Satyanarayana Rachagani, Jussuf Kaifi Clin Cancer Res 2024 Sep;30(17):3855-3867
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mosGraphGen: a novel tool to generate multi-omics signaling graphs to facilitate integrative and interpretable graph AI model development
Heming Zhang, Dekang Cao, Zirui Chen, Xiuyuan Zhang, Yixin Chen, Cole Sessions, Carlos Cruchaga, Philip Payne, Guangfu Li, Michael Province, Fuhai Li bioRxiv 2024 Aug;
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PathFinder: a novel graph transformer model to infer multi-cell intra- and inter-cellular signaling pathways and communications
Jiarui Feng, Haoran Song, Michael Province, Guangfu Li, Philip R. O. Payne, Yixin Chen, Fuhai Li Front Cell Neurosci 2024 May;01-16
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A novel role of TGFBI in macrophage polarization and macrophage-induced pancreatic cancer growth and therapeutic resistance.
Zhou, Jing; Lyu, Nan; Wang, Qiongling; Yang, Ming; Kimchi, Eric T; Cheng, Kun; Joshi, Trupti; Tukuli, Adama R; Staveley-O'Carroll, Kevin F; Li, Guangfu Cancer letters 2023 Dec;578216457
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Western diet contributes to the pathogenesis of non-alcoholic steatohepatitis in male mice via remodeling gut microbiota and increasing production of 2-oleoylglycerol.
Yang, Ming; Qi, Xiaoqiang; Li, Nan; Kaifi, Jussuf T; Chen, Shiyou; Wheeler, Andrew A; Kimchi, Eric T; Ericsson, Aaron C; Rector, R Scott; Staveley-O'Carroll, Kevin F; Li, Guangfu Nature communications 2023 Jan;14(1):228
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Nanoliposome C6-Ceramide in combination with anti-CTLA4 antibody improves anti-tumor immunity in hepatocellular cancer.
Qi, Xiaoqiang; Wu, Feng; Kim, Sung Hoon; Kaifi, Jussuf T; Kimchi, Eric T; Snyder, Helena; Illendula, Anuradha; Fox, Todd; Kester, Mark; Staveley-O'Carroll, Kevin F; Li, Guangfu FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22250
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Synergizing sunitinib and radiofrequency ablation to treat hepatocellular cancer by triggering the antitumor immune response.
Qi, Xiaoqiang; Yang, Ming; Ma, Lixin; Sauer, Madeline; Avella, Diego; Kaifi, Jussuf T; Bryan, Jeffrey; Cheng, Kun; Staveley-O'Carroll, Kevin F; Kimchi, Eric T; Li, Guangfu Journal for immunotherapy of cancer 2020 Oct;8(2):
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Disruption of oncogenic liver-intestine cadherin (CDH17) drives apoptotic pancreatic cancer death.
Liu, Xinjian; Huang, Yue; Yuan, Hao; Qi, Xiaoqiang; Manjunath, Yariswamy; Avella, Diego; Kaifi, Jussuf T; Miao, Yi; Li, Min; Jiang, Kuirong; Li, Guangfu Cancer letters 2019 Jul;454204-214
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Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice.
Li, Guangfu; Liu, Dai; Kimchi, Eric T; Kaifi, Jussuf T; Qi, Xiaoqiang; Manjunath, Yariswamy; Liu, Xinjian; Deering, Tye; Avella, Diego M; Fox, Todd; Rockey, Don C; Schell, Todd D; Kester, Mark; Staveley-O'Carroll, Kevin F Gastroenterology 2018 Mar;154(4):1024-1036.e9
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Galectin-1-driven upregulation of SDF-1 in pancreatic stellate cells promotes pancreatic cancer metastasis.
Qian, Dong; Lu, Zipeng; Xu, Qingcheng; Wu, Pengfei; Tian, Lei; Zhao, Liangtao; Cai, Baobao; Yin, Jie; Wu, Yang; Staveley-O'Carroll, Kevin F; Jiang, Kuirong; Miao, Yi; Li, Guangfu Cancer letters 2017 Jul;39743-51
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Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model.
Li, Guangfu; Liu, Dai; Cooper, Timothy K; Kimchi, Eric T; Qi, Xiaoqiang; Avella, Diego M; Li, Ningfei; Yang, Qing X; Kester, Mark; Rountree, C Bart; Kaifi, Jussuf T; Cole, David J; Rockey, Don C; Schell, Todd D; Staveley-O'Carroll, Kevin F Journal of hepatology 2017 Jan;66(1):75-85
