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Dynalogo: Interactive sequence logo with dynamic thresholding of matched quantitative proteomic data.
Lafontaine, Adam; Mayer, Bruce; Machida, Kazuya Bioinformatics (Oxford, England) 2020 Mar;
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Noonan Syndrome-Associated SHP2 Dephosphorylates GluN2B to Regulate NMDA Receptor Function.
Levy, Aaron D; Xiao, Xiao; Shaw, Juliana E; Sudarsana Devi, Suma Priya; Katrancha, Sara Marie; Bennett, Anton M; Greer, Charles A; Howe, James R; Machida, Kazuya; Koleske, Anthony J Cell reports 2018 Aug;24(6):1523-1535
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Optogenetic activation of EphB2 receptor in dendrites induced actin polymerization by activating Arg kinase.
Locke, Clifford; Machida, Kazuya; Wu, Yi; Yu, Ji Biology open 2017 Nov;61820-1830
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Crk Tyrosine Phosphorylation Regulates PDGF-BB-inducible Src Activation and Breast Tumorigenicity and Metastasis.
Kumar, Sushil; Lu, Bin; Davra, Viralkumar; Hornbeck, Peter; Machida, Kazuya; Birge, Raymond B Molecular cancer research : MCR 2017 Oct;16173-183
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Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity.
Miller, Megan B; Yan, Yan; Machida, Kazuya; Kiraly, Drew D; Levy, Aaron D; Wu, Yi I; Lam, TuKiet T; Abbott, Thomas; Koleske, Anthony J; Eipper, Betty A; Mains, Richard E ACS chemical neuroscience 2017 Apr;81554-1569
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Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells.
Rosenberg, Brian J; Gil-Henn, Hava; Mader, Christopher C; Halo, Tiffany; Yin, Taofei; Condeelis, John; Machida, Kazuya; Wu, Yi I; Koleske, Anthony J Molecular biology of the cell 2017 Mar;281347-1360
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Binding Assays Using Recombinant SH2 Domains: Far-Western, Pull-Down, and Fluorescence Polarization.
Machida, Kazuya; Liu, Bernard Methods in molecular biology (Clifton, N.J.) 2017 Jan;1555307-330
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Expression and Production of SH2 Domain Proteins.
Liu, Bernard A; Ogiue-Ikeda, Mari; Machida, Kazuya Methods in molecular biology (Clifton, N.J.) 2017 Jan;1555117-162
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Expression and Purification of SH2 Domains Using Baculovirus Expression System.
Ogiue-Ikeda, Mari; Machida, Kazuya Methods in molecular biology (Clifton, N.J.) 2017 Jan;1555183-198
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Functionally Altered SH2 Domains for Biochemical Studies: Loss-of-Function Mutant and Domain Concatenation.
Ogiue-Ikeda, Mari; Machida, Kazuya Methods in molecular biology (Clifton, N.J.) 2017 Jan;1555199-223
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In-Solution SH2 Domain Binding Assay Based on Proximity Ligation.
Machida, Kazuya Methods in molecular biology (Clifton, N.J.) 2017 Jan;1555331-347
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Introduction: History of SH2 Domains and Their Applications.
Liu, Bernard A; Machida, Kazuya Methods in molecular biology (Clifton, N.J.) 2017 Jan;15553-35
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Rosette Assay: Highly Customizable Dot-Blot for SH2 Domain Screening.
Ng, Khong Y; Machida, Kazuya Methods in molecular biology (Clifton, N.J.) 2017 Jan;1555437-451
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Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases.
Jadwin, Joshua A; Oh, Dongmyung; Curran, Timothy G; Ogiue-Ikeda, Mari; Jia, Lin; White, Forest M; Machida, Kazuya; Yu, Ji; Mayer, Bruce J eLife 2016 Jan;5e11835
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SH2-PLA: a sensitive in-solution approach for quantification of modular domain binding by proximity ligation and real-time PCR.
Thompson, Christopher M; Bloom, Lee R; Ogiue-Ikeda, Mari; Machida, Kazuya BMC biotechnology 2015 Jan;15(1):60
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Iterative tyrosine phosphorylation controls non-canonical domain utilization in Crk.
Sriram, G; Jankowski, W; Kasikara, C; Reichman, C; Saleh, T; Nguyen, K-Q; Li, J; Hornbeck, P; Machida, K; Liu, T; Li, H; Kalodimos, C G; Birge, R B Oncogene 2014 Nov;34(32):4260-9
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Phosphorylation of Dok1 by Abl family kinases inhibits CrkI transforming activity.
Ng, K Y; Yin, T; Machida, K; Wu, Y I; Mayer, B J Oncogene 2014 Jul;34(20):2650-9
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Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin.
Gifford, Stacey M; Liu, Weizhi; Mader, Christopher C; Halo, Tiffany L; Machida, Kazuya; Boggon, Titus J; Koleske, Anthony J The Journal of biological chemistry 2014 Jun;289(28):19704-13
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Paxillin kinase linker (PKL) regulates Vav2 signaling during cell spreading and migration.
Jones, Matthew C; Machida, Kazuya; Mayer, Bruce J; Turner, Christopher E Molecular biology of the cell 2013 Jun;24(12):1882-94
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The SH2 domain interaction landscape.
Tinti, Michele; Kiemer, Lars; Costa, Stefano; Miller, Martin L; Sacco, Francesca; Olsen, Jesper V; Carducci, Martina; Paoluzi, Serena; Langone, Francesca; Workman, Christopher T; Blom, Nikolaj; Machida, Kazuya; Thompson, Christopher M; Schutkowski, Mike; Brunak, Søren; Mann, Matthias; Mayer, Bruce J; Castagnoli, Luisa; Cesareni, Gianni Cell reports 2013 Apr;3(4):1293-305
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Fast rebinding increases dwell time of Src homology 2 (SH2)-containing proteins near the plasma membrane.
Oh, Dongmyung; Ogiue-Ikeda, Mari; Jadwin, Joshua A; Machida, Kazuya; Mayer, Bruce J; Yu, Ji Proceedings of the National Academy of Sciences of the United States of America 2012 Aug;109(35):14024-9
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Phosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivation.
Sriram, G; Reichman, C; Tunceroglu, A; Kaushal, N; Saleh, T; Machida, K; Mayer, B; Ge, Q; Li, J; Hornbeck, P; Kalodimos, C G; Birge, R B Oncogene 2011 Nov;30(46):4645-55
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Proteins that bind the Src homology 3 domain of CrkI have distinct roles in Crk transformation.
Zheng, J; Machida, K; Antoku, S; Ng, K Y; Claffey, K P; Mayer, B J Oncogene 2010 Dec;29(48):6378-89
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Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation.
Kelley, Laura C; Ammer, Amanda Gatesman; Hayes, Karen E; Martin, Karen H; Machida, Kazuya; Jia, Lin; Mayer, Bruce J; Weed, Scott A Journal of cell science 2010 Nov;123(Pt 22):3923-32
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Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.
Dubielecka, Patrycja M; Machida, Kazuya; Xiong, Xiaoling; Hossain, Sajjad; Ogiue-Ikeda, Mari; Carrera, Ana C; Mayer, Bruce J; Kotula, Leszek FEBS letters 2010 Aug;584(15):3279-86
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Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity.
Lazer, Galit; Pe'er, Liron; Farago, Marganit; Machida, Kazuya; Mayer, Bruce J; Katzav, Shulamit The Journal of biological chemistry 2010 Jul;285(30):23075-85
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Characterizing tyrosine phosphorylation signaling in lung cancer using SH2 profiling.
Machida, Kazuya; Eschrich, Steven; Li, Jiannong; Bai, Yun; Koomen, John; Mayer, Bruce J; Haura, Eric B PloS one 2010 Jan;5(10):e13470
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Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion.
Lapetina, Stefanie; Mader, Christopher C; Machida, Kazuya; Mayer, Bruce J; Koleske, Anthony J The Journal of cell biology 2009 May;185(3):503-19
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High-throughput phosphotyrosine profiling using SH2 domains.
Machida, Kazuya; Thompson, Christopher M; Dierck, Kevin; Jablonowski, Karl; Kärkkäinen, Satu; Liu, Bernard; Zhang, Haimin; Nash, Piers D; Newman, Debra K; Nollau, Peter; Pawson, Tony; Renkema, G Herma; Saksela, Kalle; Schiller, Martin R; Shin, Dong-Guk; Mayer, Bruce J Molecular cell 2007 Jun;26(6):899-915
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Quantitative multiplexed profiling of cellular signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains.
Dierck, Kevin; Machida, Kazuya; Voigt, Anja; Thimm, Julian; Horstmann, Martin; Fiedler, Walter; Mayer, Bruce J; Nollau, Peter Nature methods 2006 Sep;3(9):737-44
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Tyrosine phosphorylation of NOS3 in a breast cancer cell line and Src-transformed cells.
Takenouchi, Yasushi; Oo, Myat Lin; Senga, Takeshi; Watanabe, Yasuo; Machida, Kazuya; Miyazaki, Kou; Nimura, Yuji; Hamaguchi, Michinari Oncology reports 2004 May;11(5):1059-62
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A role for SHPS-1/SIRPalpha1 in IL-1beta- and TNFalpha-dependent signaling.
Ruhul Amin, Ali Reja Mohammad; Machida, Kazuya; Oshima, Kumi; Oo, Myat Lin; Thant, Aye Aye; Senga, Takeshi; Matsuda, Satoru; Akhand, Anwarul Azim; Maeda, Akito; Kurosaki, Tomohiro; Hamaguchi, Michinari Oncogene 2002 Dec;21(57):8871-8
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Hyaluronan-CD44s signaling regulates matrix metalloproteinase-2 secretion in a human lung carcinoma cell line QG90.
Zhang, Yanying; Thant, Aye Aye; Machida, Kazuya; Ichigotani, Yasukatsu; Naito, Yuko; Hiraiwa, Yukiko; Senga, Takeshi; Sohara, Yasuyoshi; Matsuda, Satoru; Hamaguchi, Michinari Cancer research 2002 Jul;62(14):3962-5
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SHPS-1: a budding molecule against cancer dissemination.
Oshima, Kumi; Machida, Kazuya; Ichigotani, Yasukatu; Nimura, Yuji; Shirafuji, Naoki; Hamaguchi, Michinari; Matsuda, Satoru Cancer research 2002 Jul;62(14):3929-33
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Hyaluronan activates cell motility of v-Src-transformed cells via Ras-mitogen-activated protein kinase and phosphoinositide 3-kinase-Akt in a tumor-specific manner.
Sohara, Y; Ishiguro, N; Machida, K; Kurata, H; Thant, A A; Senga, T; Matsuda, S; Kimata, K; Iwata, H; Hamaguchi, M Molecular biology of the cell 2001 Jun;12(6):1859-68
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Invasion activating caveolin-1 mutation in human scirrhous breast cancers.
Hayashi, K; Matsuda, S; Machida, K; Yamamoto, T; Fukuda, Y; Nimura, Y; Hayakawa, T; Hamaguchi, M Cancer research 2001 Mar;61(6):2361-4
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C-Cbl protein in human cancer tissues is frequently tyrosine phosphorylated in a tumor-specific manner.
Kamei, T; Machida, K; Nimura, Y; Senga, T; Yamada, I; Yoshii, S; Matsuda, S; Hamaguchi, M International journal of oncology 2000 Aug;17(2):335-9
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v-Src suppresses SHPS-1 expression via the Ras-MAP kinase pathway to promote the oncogenic growth of cells.
Machida, K; Matsuda, S; Yamaki, K; Senga, T; Thant, A A; Kurata, H; Miyazaki, K; Hayashi, K; Okuda, T; Kitamura, T; Hayakawa, T; Hamaguchi, M Oncogene 2000 Mar;19(13):1710-8
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Clustered cysteine residues in the kinase domain of v-Src: critical role for protein stability, cell transformation and sensitivity to herbimycin A.
Senga, T; Miyazaki, K; Machida, K; Iwata, H; Matsuda, S; Nakashima, I; Hamaguchi, M Oncogene 2000 Jan;19(2):273-9
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Molecular cloning and characterization of human MAWD, a novel protein containing WD-40 repeats frequently overexpressed in breast cancer.
Matsuda, S; Katsumata, R; Okuda, T; Yamamoto, T; Miyazaki, K; Senga, T; Machida, K; Thant, A A; Nakatsugawa, S; Hamaguchi, M Cancer research 2000 Jan;60(1):13-7
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Molecular cloning of a novel human gene (SIRP-B2) which encodes a new member of the SIRP/SHPS-1 protein family.
Ichigotani, Y; Matsuda, S; Machida, K; Oshima, K; Iwamoto, T; Yamaki, K; Hayakawa, T; Hamaguchi, M Journal of human genetics 2000 Jan;45(6):378-82
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Ras pathway is required for the activation of MMP-2 secretion and for the invasion of src-transformed 3Y1.
Thant, A A; Sein, T T; Liu, E; Machida, K; Kikkawa, F; Koike, T; Seiki, M; Matsuda, S; Hamaguchi, M Oncogene 1999 Nov;18(47):6555-63
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Critical amino acid substitutions in the Src SH3 domain that convert c-Src to be oncogenic.
Miyazaki, K; Senga, T; Matsuda, S; Tanaka, M; Machida, K; Takenouchi, Y; Nimura, Y; Hamaguchi, M Biochemical and biophysical research communications 1999 Oct;263(3):759-64
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Hyaluronan activates mitogen-activated protein kinase via Ras-signaling pathway.
Serbulea, M; Kakumu, S; Thant, A A; Miyazaki, K; Machida, K; Senga, T; Ohta, S; Yoshioka, K; Hotta, N; Hamaguchi, M International journal of oncology 1999 Apr;14(4):733-8
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Suppression of cell growth by ectopic expression of N-cadherin.
Wang, X; Thant, A A; Machida, K; Hiraiwa, Y; Iwata, H; Matsuda, S; Hamaguchi, M International journal of oncology 1998 May;12(5):1097-101
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[Cell transformation by Src kinase: role of cell adhesion system as a signal transducer].
Hamaguchi, M; Wang, X D; Machida, K; Itoh, Y Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997 Jul;42(10 Suppl):1687-93
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[Thromboxane A2 synthetase inhibitor in asthma therapy].
Machida, K; Takagi, K; Horiba, M Nihon rinsho. Japanese journal of clinical medicine 1996 Nov;54(11):3034-9
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Tyrosine phosphorylation of 100-130 kDa proteins in lung cancer correlates with poor prognosis.
Nishimura, M; Machida, K; Imaizumi, M; Abe, T; Umeda, T; Takeshima, E; Watanabe, T; Ohnishi, Y; Takagi, K; Hamaguchi, M British journal of cancer 1996 Sep;74(5):780-7
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[Home days ratio in patients treated with long-term oxygen therapy].
Ando, M; Horiba, M; Sumita, T; Shindo, J; Machida, K; Takagi, K Nihon Kyobu Shikkan Gakkai zasshi 1995 Oct;33(10):1086-92
