Faculty Directory › UConn Health

Antoine L. Menoret, PhD

Instructor, Immunology


Academic Office Location: Immunology UConn Health 263 Farmington Avenue Farmington, CT 06030-3710
Phone:	860-679-6528
Fax:	860-679-8130

Publications
Presentations

Journal Articles

Autoregulated splicing of TRA2β programs T cell fate in response to antigen-receptor stimulation.
Karginov, Timofey A; Ménoret, Antoine; Leclair, Nathan K; Harrison, Andrew G; Chandiran, Karthik; Suarez-Ramirez, Jenny E; Yurieva, Marina; Karlinsey, Keaton; Wang, Penghua; O'Neill, Rachel J; Murphy, Patrick A; Adler, Adam J; Cauley, Linda S; Anczuków, Olga; Zhou, Beiyan; Vella, Anthony T Science (New York, N.Y.) 2024 Sep;385(6714):eadj1979
Endothelial Immunosuppression in Atherosclerosis : Translational Control by Elavl1/HuR.
Nicholas, Sarah-Anne E; Helming, Stephen R; Ménoret, Antoine; Pathoulas, Christopher; Xu, Maria M; Hensel, Jessica; Kimble, Amy L; Heineman, Brent; Jellison, Evan R; Reese, Bo; Zhou, Beiyan; Rodriguez-Oquendo, Annabelle; Vella, Anthony T; Murphy, Patrick A bioRxiv : the preprint server for biology 2024 Aug;
IRAK4 is an immunological checkpoint in neuropsychiatric systemic lupus erythematosus.
Ménoret, Antoine; Agliano, Federica; Karginov, Timofey A; Hu, Xiangyou; Vella, Anthony T Scientific reports 2024 Jul;14(1):16393
Astrocytic TIMP-1 regulates production of Anastellin, an inhibitor of oligodendrocyte differentiation and FTY720 responses.
Sutter, Pearl A; Willis, Cory M; Menoret, Antoine; Nicaise, Alexandra M; Sacino, Anthony; Sikkema, Arend H; Jellison, Evan R; Win, Kyaw K; Han, David K; Church, William; Baron, Wia; Vella, Anthony T; Crocker, Stephen J Proceedings of the National Academy of Sciences of the United States of America 2024 Jan;121(5):e2306816121
Interleukin-17 directly stimulates tumor infiltrating Tregs to prevent cancer development.
Theune, William C; Chen, Ju; Theune, Eileen Victoria; Ye, Xiaoyang; Ménoret, Antoine; Vella, Anthony T; Wang, Kepeng Frontiers in immunology 2024 Jan;151408710
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy.
Sutter, Pearl A; Ménoret, Antoine; Jellison, Evan R; Nicaise, Alexandra M; Bradbury, Allison M; Vella, Anthony T; Bongarzone, Ernesto R; Crocker, Stephen J The Journal of experimental medicine 2023 Sep;220(9):
Astrocytic TIMP-1 regulates production of Anastellin, a novel inhibitor of oligodendrocyte differentiation and FTY720 responses.
Sutter, Pearl A; Willis, Cory M; Menoret, Antoine; Nicaise, Alexandra M; Sacino, Anthony; Sikkema, Arend H; Jellison, Evan; Win, Kyaw K; Han, David K; Church, William; Baron, Wia; Vella, Anthony T; Crocker, Stephen J bioRxiv : the preprint server for biology 2023 Feb;
Antigen-specific downregulation of miR-150 in CD4 T cells promotes cell survival.
Ménoret, Antoine; Agliano, Federica; Karginov, Timofey A; Karlinsey, Keaton S; Zhou, Beiyan; Vella, Anthony T Frontiers in immunology 2023 Jan;141102403
Splice factor polypyrimidine tract-binding protein 1 (Ptbp1) primes endothelial inflammation in atherogenic disturbed flow conditions.
Hensel, Jessica A; Nicholas, Sarah-Anne E; Kimble, Amy L; Nagpal, Arjun S; Omar, Omar M F; Tyburski, Jordan D; Jellison, Evan R; Ménoret, Antoine; Ozawa, Manabu; Rodriguez-Oquendo, Annabelle; Vella, Anthony T; Murphy, Patrick A Proceedings of the National Academy of Sciences of the United States of America 2022 Jul;119(30):e2122227119
Optimal CD8+ T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape.
Karginov, Timofey A; Ménoret, Antoine; Vella, Anthony T Nature communications 2022 Jun;13(1):3540
Evaluating the glycolytic potential of mouse costimulated effector CD8+ T cells ex vivo.
Agliano, Federica; Ménoret, Antoine; Vella, Anthony T STAR protocols 2022 Jun;3(2):101441
Nicotinamide breaks effector CD8 T cell responses by targeting mTOR signaling.
Agliano, Federica; Karginov, Timofey A; Ménoret, Antoine; Provatas, Anthony; Vella, Anthony T iScience 2022 Mar;25(3):103932
A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients
Chuan Li, Yee Peng Phoon, Keaton Karlinsey, Ye F Tian, Samjhana Thapaliya, Angkana Thongkum, Lili Qu, Alyssa Joyce Matz, Mark Cameron, Cheryl Cameron, Antoine Menoret, Pauline Funchain, Jung-Min Song, C Marcela Diaz-Montero, Banumathi Tamilselvan, Jackelyn B Golden, Michael Cartwright, Annabelle Rodriguez, Christopher Bonin, Anthony Vella, Beiyan Zhou, Brian R Gastman J Exp Med. 2022 Jan;219(1):
Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin.
Russo, Ashley J; Vasudevan, Swathy O; Méndez-Huergo, Santiago P; Kumari, Puja; Menoret, Antoine; Duduskar, Shivalee; Wang, Chengliang; Pérez Sáez, Juan M; Fettis, Margaret M; Li, Chuan; Liu, Renjie; Wanchoo, Arun; Chandiran, Karthik; Ruan, Jianbin; Vanaja, Sivapriya Kailasan; Bauer, Michael; Sponholz, Christoph; Hudalla, Gregory A; Vella, Anthony T; Zhou, Beiyan; Deshmukh, Sachin D; Rabinovich, Gabriel A; Rathinam, Vijay A Nature immunology 2021 Feb;22(2):154-165
A benzimidazole inhibitor attenuates sterile inflammation induced in a model of systemic autoinflammation in female mice.
Agliano, Federica; Karlinsey, Keaton S; Ragazzi, Michael; Ménoret, Antoine; Vella, Anthony T Scientific reports 2020 Jul;10(1):12100
GRK2 enforces androgen receptor dependence in the prostate and prostate tumors.
Adler, Adam J; Mittal, Payal; Hagymasi, Adam T; Menoret, Antoine; Shen, Chen; Agliano, Federica; Wright, Kyle T; Grady, James J; Kuo, Chia-Ling; Ballesteros, Enrique; Claffey, Kevin P; Vella, Anthony T Oncogene 2020 Jan;
Extracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis.
Willis, Cory M; Nicaise, Alexandra M; Menoret, Antoine; Ryu, Jae Kyu; Mendiola, Andrew S; Jellison, Evan R; Givogri, Maria I; Han, David K; Bongarzone, Ernesto R; Akassoglou, Katerina; Vella, Anthony T; Crocker, Stephen J Proceedings of the National Academy of Sciences of the United States of America 2019 May;116(21):10488-10493
Costimulation Induces CD4 T Cell Antitumor Immunity via an Innate-like Mechanism.
Morales Del Valle, Crystal; Maxwell, Joseph R; Xu, Maria M; Menoret, Antoine; Mittal, Payal; Tsurutani, Naomi; Adler, Adam J; Vella, Anthony T Cell reports 2019 Apr;27(5):1434-1445.e3
Single cell transcriptomics based-MacSpectrum reveals novel macrophage activation signatures in diseases.
Li, Chuan; Menoret, Antoine; Farragher, Cullen; Ouyang, Zhengqing; Bonin, Christopher; Holvoet, Paul; Vella, Anthony T; Zhou, Beiyan JCI insight 2019 Apr;5
Direct CD137 costimulation of CD8 T cells promotes retention and innate-like function within nascent atherogenic foci.
Xu, Maria Mei; Ménoret, Antoine; Nicholas, Sarah-Anne E; Günther, Sebastian; Sundberg, Eric J; Zhou, Beiyan; Rodriguez, Annabelle; Murphy, Patrick A; Vella, Anthony T American journal of physiology. Heart and circulatory physiology 2019 Apr;
Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis.
Banerjee, Ishita; Behl, Bharat; Mendonca, Morena; Shrivastava, Gaurav; Russo, Ashley J; Menoret, Antoine; Ghosh, Arundhati; Vella, Anthony T; Vanaja, Sivapriya Kailasan; Sarkar, Saumendra N; Fitzgerald, Katherine A; Rathinam, Vijay A K Immunity 2018 Aug;49413-426.e5
T cell-directed IL-17 production by lung granular γδ T cells is coordinated by a novel IL-2 and IL-1β circuit.
Ménoret, Antoine; Buturla, James A; Xu, Maria M; Svedova, Julia; Kumar, Sanjeev; Rathinam, Vijay A K; Vella, Anthony T Mucosal immunology 2018 Jun;111398-1407
A novel biologic platform elicits profound T cell costimulatory activity and antitumor immunity in mice.
Ryan, Joseph M; Mittal, Payal; Menoret, Antoine; Svedova, Julia; Wasser, Jeffrey S; Adler, Adam J; Vella, Anthony T Cancer immunology, immunotherapy : CII 2018 Jan;67605-613
Therapeutic blockade of CD54 attenuates pulmonary barrier damage in T cell-induced acute lung injury.
Svedova, Julia; Ménoret, Antoine; Mittal, Payal; Ryan, Joseph M; Buturla, James A; Vella, Anthony T American journal of physiology. Lung cellular and molecular physiology 2017 May;313L177-L191
Optimal CD4 T cell priming after LPS-based adjuvanticity with CD134 costimulation relies on CXCL9 production.
Shinde, Paurvi; Liu, Wenhai; Ménoret, Antoine; Luster, Andrew D; Vella, Anthony T Journal of leukocyte biology 2017 Apr;10257-69
Costimulation Endows Immunotherapeutic CD8 T Cells with IL-36 Responsiveness during Aerobic Glycolysis.
Tsurutani, Naomi; Mittal, Payal; St Rose, Marie-Clare; Ngoi, Soo Mun; Svedova, Julia; Menoret, Antoine; Treadway, Forrest B; Laubenbacher, Reinhard; Suárez-Ramírez, Jenny E; Cauley, Linda S; Adler, Adam J; Vella, Anthony T Journal of immunology (Baltimore, Md. : 1950) 2015 Nov;196124-34
Responses to LPS boost effector CD8 T-cell accumulation outside of signals 1 and 2.
Liu, Wenhai; Menoret, Antoine; Vella, Anthony T Cellular & molecular immunology 2015 Jul;14254-253
Trace Levels of Staphylococcal Enterotoxin Bioactivity Are Concealed in a Mucosal Niche during Pulmonary Inflammation.
Ménoret, Antoine; Svedova, Julia; Behl, Bharat; Vella, Anthony T PloS one 2015 Jan;10(10):e0141548
Distinctive colonic mucosal cytokine signature in new-onset, untreated pediatric Crohn disease.
Sylvester, Francisco A; Draghi, Andrew; Menoret, Antoine; Fernandez, Marina L; Wang, Zhu; Vella, Anthony T Journal of pediatric gastroenterology and nutrition 2014 Jul;59(5):553-61
Rapid αβ T-cell responses orchestrate innate immunity in response to Staphylococcal enterotoxin A.
Kumar, S; Colpitts, S L; Ménoret, A; Budelsky, A L; Lefrancois, L; Vella, A T Mucosal immunology 2013 Sep;6(5):1006-15
Differential proteomics identifies PDIA3 as a novel chemoprevention target in human colon cancer cells.
Ménoret, Antoine; Drew, David A; Miyamoto, Shingo; Nakanishi, Masako; Vella, Anthony T; Rosenberg, Daniel W Molecular carcinogenesis 2012 Dec;53 Suppl 1E11-22
Presensitizing with a Toll-like receptor 3 ligand impairs CD8 T-cell effector differentiation and IL-33 responsiveness.
Ngoi, Soo Mun; St Rose, Marie-Clare; Menoret, Antoine M; Smith, Dirk E; Tovey, Michael G; Adler, Adam J; Vella, Anthony T Proceedings of the National Academy of Sciences of the United States of America 2012 Jun;109(26):10486-91
Cytochrome b5 and cytokeratin 17 are biomarkers in bronchoalveolar fluid signifying onset of acute lung injury.
Ménoret, Antoine; Kumar, Sanjeev; Vella, Anthony T PloS one 2012 Jan;7(7):e40184
CD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells to program cytotoxic Th1 differentiation.
Qui, Harry Z; Hagymasi, Adam T; Bandyopadhyay, Suman; St Rose, Marie-Clare; Ramanarasimhaiah, Raghunath; Ménoret, Antoine; Mittler, Robert S; Gordon, Scott M; Reiner, Steven L; Vella, Anthony T; Adler, Adam J Journal of immunology (Baltimore, Md. : 1950) 2011 Oct;187(7):3555-64
Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity.
Nakanishi, Masako; Menoret, Antoine; Tanaka, Takuji; Miyamoto, Shingo; Montrose, David C; Vella, Anthony T; Rosenberg, Daniel W Cancer prevention research (Philadelphia, Pa.) 2011 Aug;4(8):1198-208
The oxazolidinone derivative locostatin induces cytokine appeasement.
Ménoret, Antoine; McAleer, Jeremy P; Ngoi, Soo-Mun; Ray, Swagatam; Eddy, Nicholas A; Fenteany, Gabriel; Lee, Seung-Joo; Rossi, Robert J; Mukherji, Bijay; Allen, David L; Chakraborty, Nitya G; Vella, Anthony T Journal of immunology (Baltimore, Md. : 1950) 2009 Dec;183(11):7489-96
Utilizing endoscopic technology to reveal real-time proteomic alterations in response to chemoprevention.
Nakanishi, Masako; Ménoret, Antoine; Belinsky, Glenn S; Giardina, Charles; Godman, Cassandra A; Vella, Anthony T; Rosenberg, Daniel W Proteomics. Clinical applications 2007 Dec;1(12):1660-6
Heat shock up-regulates lmp2 and lmp7 and enhances presentation of immunoproteasome-dependent epitopes.
Callahan, Margaret K; Wohlfert, Elizabeth A; Ménoret, Antoine; Srivastava, Pramod K Journal of immunology (Baltimore, Md. : 1950) 2006 Dec;177(12):8393-9
TGFbeta protein processing and activity through TCR triggering of primary CD8+ T regulatory cells.
Ménoret, Antoine; Myers, Lara M; Lee, Seung-Joo; Mittler, Robert S; Rossi, Robert J; Vella, Anthony T Journal of immunology (Baltimore, Md. : 1950) 2006 Nov;177(9):6091-7
Inducible heat shock protein 70 expression as a potential predictive marker of metastasis in breast tumors.
Torronteguy, Carolina; Frasson, Antonio; Zerwes, Felipe; Winnikov, Erik; da Silva, Vinicius Duval; Ménoret, Antoine; Bonorino, Cristina Cell stress & chaperones 2006 Jan;11(1):34-43
Purification of recombinant and endogenous HSP70s.
Ménoret, Antoine Methods (San Diego, Calif.) 2004 Jan;32(1):7-12
Differential acquisition of antigenic peptides by Hsp70 and Hsc70 under oxidative conditions.
Callahan, Margaret K; Chaillot, Delphine; Jacquin, Claire; Clark, Paul R; Ménoret, Antoine The Journal of biological chemistry 2002 Sep;277(37):33604-9
An endoplasmic reticulum protein implicated in chaperoning peptides to major histocompatibility of class I is an aminopeptidase.
Ménoret, A; Li, Z; Niswonger, M L; Altmeyer, A; Srivastava, P K The Journal of biological chemistry 2001 Sep;276(36):33313-8
The inducible Hsp70 as a marker of tumor immunogenicity.
Clark, P R; Ménoret, A Cell stress & chaperones 2001 Apr;6(2):121-5
Definition of a novel binding site on CD8 cells for a conserved region of the MHC class Ib molecule Qa-1 that regulates IFN-gamma expression.
Wang, R; Ramaswamy, S; Hu, D; Cantor, H European journal of immunology 2001 Jan;31(1):87-93
Phylogenetic conservation of the molecular and immunological properties of the chaperones gp96 and hsp70.
Robert, J; Ménoret, A; Basu, S; Cohen, N; Srivastava, P R European journal of immunology 2001 Jan;31(1):186-95
Natural autoantibodies against heat-shock proteins hsp70 and gp96: implications for immunotherapy using heat-shock proteins.
Ménoret, A; Chandawarkar, R Y; Srivastava, P K Immunology 2000 Nov;101(3):364-70
Saturation, competition, and specificity in interaction of heat shock proteins (hsp) gp96, hsp90, and hsp70 with CD11b+ cells.
Binder, R J; Harris, M L; Ménoret, A; Srivastava, P K Journal of immunology (Baltimore, Md. : 1950) 2000 Sep;165(5):2582-7
Purification of multiple heat shock proteins from a single tumor sample.
Ménoret, A; Bell, G Journal of immunological methods 2000 Apr;237(1-2):119-30
Cell surface expression of the endoplasmic reticular heat shock protein gp96 is phylogenetically conserved.
Robert, J; Ménoret, A; Cohen, N Journal of immunology (Baltimore, Md. : 1950) 1999 Oct;163(8):4133-9
Association of peptides with heat shock protein gp96 occurs in vivo and not after cell lysis.
Ménoret, A; Peng, P; Srivastava, P K Biochemical and biophysical research communications 1999 Sep;262(3):813-8
The endoplasmic reticular heat shock protein Gp96 is an aminopeptidase
Menoret A., Srivastava P.K. FASEB Journal 1998 Jan;12(4):
Purification of immunogenic heat shock protein 70-peptide complexes by ADP-affinity chromatography.
Peng, P; Ménoret, A; Srivastava, P K Journal of immunological methods 1997 May;204(1):13-21
Splice Factor Polypyrimidine tract-binding protein 1 (Ptbp1) is Required for Immune Priming of the Endothelium in Atherogenic Disturbed Flow Conditions
Jessica A Hensel, Sarah-Anne E Nicholas, Evan R Jellison, Amy L Kimble, Antoine Menoret, Manabu Ozawa, Annabelle Rodriguez-Oquendo, Anthony T Vella, Patrick A Murphy

Reviews

Transition from identity to bioactivity-guided proteomics for biomarker discovery with focus on the PF2D platform.
Ménoret, Antoine; Crocker, Stephen J; Rodriguez, Annabelle; Rathinam, Vijay A; Clark, Robert B; Vella, Anthony T Proteomics. Clinical applications 2016 Jan;10(1):8-24
Roles of heat-shock proteins in antigen presentation and cross-presentation.
Li, Zihai; Menoret, Antoine; Srivastava, Pramod Current opinion in immunology 2002 Feb;14(1):45-51
Hsp70, an immunological actor playing with the intracellular self under oxidative stress.
Ménoret, A; Chaillot, D; Callahan, M; Jacquin, C International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2002 Jan;18(6):490-505
Heat-shock protein-based anticancer immunotherapy: an idea whose time has come.
Ménoret, A; Chandawarkar, R Seminars in oncology 1998 Dec;25(6):654-60
Heat shock proteins come of age: primitive functions acquire new roles in an adaptive world.
Srivastava, P K; Menoret, A; Basu, S; Binder, R J; McQuade, K L Immunity 1998 Jun;8(6):657-65

Title or Abstract	Type	Sponsor/Event	Date/Year	Location
Tra2b ultraconserved poison exon governs T bcell receptor signaling to shape T cell fate.	Poster		2023	ColdSpring Harbor, NY
Splicing of ultraconserved poison exon elements in RNA binding proteins reprograms the T effector immune response.	Poster	American Association of Immunologists Meeting 2023	2023	Washington DC
Splicing of Ultraconserved Poison Exon Elements in RNA Binding Proteins Reprograms the T Effector Immune Response	Poster	Cold Spring Harbor: Gene Expression and Signaling in the Immune System.	2022	. Cold Spring Harbor, NY, USA
Splicing of Ultraconserved Poison Exon Elements in RNA Binding Proteins Reprograms the T Effector Immune Response	Poster	2022 Symposium on RNA Biology XIV: RNA Tool and Target	2022	. Research Triangle Park, NC, USA
Splicing of Ultraconserved Poison Exon Elements in RNA Binding Proteins Reprograms the T Effector Immune Response	Poster	NEIC (New England Immunology Conference)	2022	NEIC (New England Immunology Conference). Woods Hole, MA, USA
T Cell Activation Induces Splicing of Ultraconserved Poison Exon Elements in RNA Binding Proteins to Allow Expansion and Effector Function During Immune Response	Poster		2022	GRC (Gordon Research Conference) Newry, ME, USA
Optimal CD8+ T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape. Selected Short Talk and Poster Presentation	Poster	American Association of Immunologists Meeting 2022	2022	Portland, OR, USA
Inhibition of CD8+ T-cells presents clinical disease and CNS myelin pathology in a mouse model of Globoid Cell Leukodystrophy	Poster	Annual Neuroscience Retreat	2022	UConn Health, Farmington, CT
Inhibition of CD8+ T-cells presents clinical disease and CNS myelin pathology in a mouse model of Globoid Cell Leukodystrophy	Poster	52nd Annual American Society for Neurochemistry	2022	Roanoke, VA.
Inhibition of CD8+ T-cells presents clinical disease and CNS myelin pathology in a mouse model of Globoid Cell Leukodystrophy	Poster	Annual AAP/ASCI/APSA Joint Meeting	2022	Chicago, IL.
Optimal CD8+ T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape	Poster	New England Immunology Conference	2021	Woods Hole, MA
Nicotinamide is a regulator of CD8+ T cell response, metabolism and fate	Poster	New England Immunology Conference	2021	Woods Hole, MA
Endothelial RNA-binding Protein Elavl1 (HuR) Regulates Alternative Splicing of Genes Involved in Adaptive Immunity and Increases T cells in the Atherosclerotic Intima.	Poster	North American Vascular Biology Organization Vascular Biology 2019	2019	Pacific Grove, CA
Synergistic stimulation by OX40 and 41BB: Transcriptional regulation in dual costimulated CD8+ T cells. Poster Presentation.	Poster	New England Immunology Conference	2019	Woods Hole, MA
Noncanonical Inflammasome-Induced release of Alarmins during Sepsis	Poster	American Association of Immunologist meeting	2019	San Diego
IRAK 1/4 inhibition attenuates sterile inflammation induced in a model of auto-inflammatory syndrome	Poster	New England Immunology Conference	2019	Woods Hole, MA

Title or Abstract

Type

Sponsor/Event

Date/Year

Location

Tra2b ultraconserved poison exon governs T bcell receptor signaling to shape T cell fate.

Poster

2023

ColdSpring Harbor, NY

Splicing of ultraconserved poison exon elements in RNA binding proteins reprograms the T effector immune response.

Poster

American Association of Immunologists Meeting 2023

2023

Washington DC

Splicing of Ultraconserved Poison Exon Elements in RNA Binding Proteins Reprograms the T Effector Immune Response

Poster

Cold Spring Harbor: Gene Expression and Signaling in the Immune System.

2022

. Cold Spring Harbor, NY, USA

Splicing of Ultraconserved Poison Exon Elements in RNA Binding Proteins Reprograms the T Effector Immune Response

Poster

2022 Symposium on RNA Biology XIV: RNA Tool and Target

2022

. Research Triangle Park, NC, USA

Splicing of Ultraconserved Poison Exon Elements in RNA Binding Proteins Reprograms the T Effector Immune Response

Poster

NEIC (New England Immunology Conference)

2022

NEIC (New England Immunology Conference). Woods Hole, MA, USA

T Cell Activation Induces Splicing of Ultraconserved Poison Exon Elements in RNA Binding Proteins to Allow Expansion and Effector Function During Immune Response

Poster

2022

GRC (Gordon Research Conference) Newry, ME, USA

Optimal CD8+ T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape. Selected Short Talk and Poster Presentation

Poster

American Association of Immunologists Meeting 2022

2022

Portland, OR, USA

Inhibition of CD8+ T-cells presents clinical disease and CNS myelin pathology in a mouse model of Globoid Cell Leukodystrophy

Poster

Annual Neuroscience Retreat

2022

UConn Health, Farmington, CT

Inhibition of CD8+ T-cells presents clinical disease and CNS myelin pathology in a mouse model of Globoid Cell Leukodystrophy

Poster

52nd Annual American Society for Neurochemistry

2022

Roanoke, VA.

Inhibition of CD8+ T-cells presents clinical disease and CNS myelin pathology in a mouse model of Globoid Cell Leukodystrophy

Poster

Annual AAP/ASCI/APSA Joint Meeting

2022

Chicago, IL.

Optimal CD8+ T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape

Poster

New England Immunology Conference

2021

Woods Hole, MA

Nicotinamide is a regulator of CD8+ T cell response, metabolism and fate

Poster

New England Immunology Conference

2021

Woods Hole, MA

Endothelial RNA-binding Protein Elavl1 (HuR) Regulates Alternative Splicing of Genes Involved in Adaptive Immunity and Increases T cells in the Atherosclerotic Intima.

Poster

North American Vascular Biology Organization Vascular Biology 2019

2019

Pacific Grove, CA

Synergistic stimulation by OX40 and 41BB: Transcriptional regulation in dual costimulated CD8+ T cells. Poster Presentation.

Poster

New England Immunology Conference

2019

Woods Hole, MA

Noncanonical Inflammasome-Induced release of Alarmins during Sepsis

Poster

American Association of Immunologist meeting

2019

San Diego

IRAK 1/4 inhibition attenuates sterile inflammation induced in a model of auto-inflammatory syndrome

Poster

New England Immunology Conference

2019

Woods Hole, MA