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Activation induced cell death (AICD) of human melanoma antigen-specific TCR engineered CD8 T cells involves JNK, Bim and p53.
Chhabra, Arvind; Mukherji, Bijay; Batra, Deepika Expert opinion on therapeutic targets 2016 Dec;21117-129
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Suppression of inducible CD4 regulatory cells by MHC class I-restricted human tumor epitope specific TCR engineered multifunctional CD4 T cells.
Chhabra, Arvind; Mukherji, Bijay Human immunology 2016 Jun;77905-911
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Knockdown of T-bet expression in Mart-127-35 -specific T-cell-receptor-engineered human CD4(+) CD25(-) and CD8(+) T cells attenuates effector function.
Jha, Sidharth S; Chakraborty, Nitya G; Singh, Prashant; Mukherji, Bijay; Dorsky, David I Immunology 2014 Dec;145(1):124-35
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Death receptor-independent activation-induced cell death in human melanoma antigen-specific MHC class I-restricted TCR-engineered CD4 T cells.
Chhabra, Arvind; Mukherji, Bijay Journal of immunology (Baltimore, Md. : 1950) 2013 Sep;191(6):3471-7
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The oxazolidinone derivative locostatin induces cytokine appeasement.
Ménoret, Antoine; McAleer, Jeremy P; Ngoi, Soo-Mun; Ray, Swagatam; Eddy, Nicholas A; Fenteany, Gabriel; Lee, Seung-Joo; Rossi, Robert J; Mukherji, Bijay; Allen, David L; Chakraborty, Nitya G; Vella, Anthony T Journal of immunology (Baltimore, Md. : 1950) 2009 Dec;183(11):7489-96
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Inhibition of superoxide generation upon T-cell receptor engagement rescues Mart-1(27-35)-reactive T cells from activation-induced cell death.
Norell, Håkan; Martins da Palma, Telma; Lesher, Aaron; Kaur, Navtej; Mehrotra, Meenal; Naga, Osama S; Spivey, Natalie; Olafimihan, Seye; Chakraborty, Nitya G; Voelkel-Johnson, Christina; Nishimura, Michael I; Mukherji, Bijay; Mehrotra, Shikhar Cancer research 2009 Aug;69(15):6282-9
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Obstacles to and opportunities for more effective peptide-based therapeutic immunization in human melanoma.
Ray, Swagatam; Chhabra, Arvind; Mehrotra, Shikhar; Chakraborty, Nitya G; Ribas, Antoni; Economou, James; Mukherji, Bijay Clinics in dermatology 2009 Jan;27(6):603-13
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CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model.
Chhabra, Arvind; Yang, Lili; Wang, Pin; Comin-Anduix, Begoña; Das, Raja; Chakraborty, Nitya G; Ray, Swagatam; Mehrotra, Shikhar; Yang, Haiguang; Hardee, Cinnamon L; Hollis, Roger; Dorsky, David I; Koya, Richard; Kohn, Donald B; Ribas, Antoni; Economou, James S; Baltimore, David; Mukherji, Bijay Journal of immunology (Baltimore, Md. : 1950) 2008 Jul;181(2):1063-70
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Silencing of endogenous IL-10 in human dendritic cells leads to the generation of an improved CTL response against human melanoma associated antigenic epitope, MART-1 27-35.
Chhabra, Arvind; Chakraborty, Nitya G; Mukherji, Bijay Clinical immunology (Orlando, Fla.) 2008 Mar;126(3):251-9
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Activation-induced cell death of human melanoma specific cytotoxic T lymphocytes is mediated by apoptosis-inducing factor.
Chhabra, Arvind; Mehrotra, Shikhar; Chakraborty, Nitya G; Dorsky, David I; Mukherji, Bijay European journal of immunology 2006 Dec;36(12):3167-74
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Macrophages as stimulators of MART-1 27-35 epitope-specific human cytolytic T lymphocytes in vitro.
Mehrotra, Shikhar; Zaidi, Nisar; Chakraborty, Nitya G; Mukherji, Bijay Pathobiology : journal of immunopathology, molecular and cellular biology 2006 Jan;73(5):238-43
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Antigen presentation by MART-1 adenovirus-transduced interleukin-10-polarized human monocyte-derived dendritic cells.
Mehrotra, Shikhar; Chhabra, Arvind; Chakraborty, Abolokita; Chattopadhyay, Subhasis; Slowik, Mark; Stevens, Robert; Zengou, Ryan; Mathias, Clinton; Butterfield, Lisa H; Dorsky, David I; Economou, James S; Mukherji, Bijay; Chakraborty, Nitya G Immunology 2004 Dec;113(4):472-81
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Rescuing melanoma epitope-specific cytolytic T lymphocytes from activation-induced cell death, by SP600125, an inhibitor of JNK: implications in cancer immunotherapy.
Mehrotra, Shikhar; Chhabra, Arvind; Chattopadhyay, Subhasis; Dorsky, David I; Chakraborty, Nitya G; Mukherji, Bijay Journal of immunology (Baltimore, Md. : 1950) 2004 Nov;173(10):6017-24
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Cross-presentation of a human tumor antigen delivered to dendritic cells by HSV VP22-mediated protein translocation.
Chhabra, Arvind; Mehrotra, Shikhar; Chakraborty, Nitya G; Mukherji, Bijay; Dorsky, David I European journal of immunology 2004 Oct;34(10):2824-33
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Regulatory T-cell response and tumor vaccine-induced cytotoxic T lymphocytes in human melanoma.
Chakraborty, Nitya G; Chattopadhyay, Subhasis; Mehrotra, Shikhar; Chhabra, Arvind; Mukherji, Bijay Human immunology 2004 Aug;65(8):794-802
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Human dendritic cell maturation by adenovirus transduction enhances tumor antigen-specific T-cell responses.
Schumacher, Lana; Ribas, Antoni; Dissette, Vivian B; McBride, William H; Mukherji, Bijay; Economou, James S; Butterfield, Lisa H Journal of immunotherapy (Hagerstown, Md. : 1997) 2004 Jan;27(3):191-200
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Determinant spreading associated with clinical response in dendritic cell-based immunotherapy for malignant melanoma.
Butterfield, Lisa H; Ribas, Antoni; Dissette, Vivian B; Amarnani, Saral N; Vu, Huong T; Oseguera, Denise; Wang, He-Jing; Elashoff, Robert M; McBride, William H; Mukherji, Bijay; Cochran, Alistair J; Glaspy, John A; Economou, James S Clinical cancer research : an official journal of the American Association for Cancer Research 2003 Mar;9(3):998-1008
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Stimulatory and inhibitory differentiation of human myeloid dendritic cells.
Chakraborty, A; Li, L; Chakraborty, N G; Mukherji, B Clinical immunology (Orlando, Fla.) 2000 Feb;94(2):88-98
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Myeloablative chemotherapy with autologous peripheral blood stem cell transplantation for metastatic breast cancer: immunologic consequences affecting clinical outcome.
Chakraborty, N; Bilgrami, S; Maness, L; Guo, C; Perez-Diez, A; Mukherji, B; Tutschka, P Bone marrow transplantation 1999 Oct;24(8):837-43
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Emergence of regulatory CD4+ T cell response to repetitive stimulation with antigen-presenting cells in vitro: implications in designing antigen-presenting cell-based tumor vaccines.
Chakraborty, N G; Li, L; Sporn, J R; Kurtzman, S H; Ergin, M T; Mukherji, B Journal of immunology (Baltimore, Md. : 1950) 1999 May;162(9):5576-83
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Varicella zoster virus infection associated with high-dose chemotherapy and autologous stem-cell rescue.
Bilgrami, S; Chakraborty, N G; Rodriguez-Pinero, F; Khan, A M; Feingold, J M; Bona, R D; Edwards, R L; Dorsky, D; Clive, J; Mukherji, B; Tutschka, P J Bone marrow transplantation 1999 Mar;23(5):469-74
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Generation of CD8+ and CD4+ T-cell response to dendritic cells genetically engineered to express the MART-1/Melan-A gene.
Pérez-Díez, A; Butterfield, L H; Li, L; Chakraborty, N G; Economou, J S; Mukherji, B Cancer research 1998 Dec;58(23):5305-9
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Generation of melanoma-specific cytotoxic T lymphocytes by dendritic cells transduced with a MART-1 adenovirus.
Butterfield, L H; Jilani, S M; Chakraborty, N G; Bui, L A; Ribas, A; Dissette, V B; Lau, R; Gamradt, S C; Glaspy, J A; McBride, W H; Mukherji, B; Economou, J S Journal of immunology (Baltimore, Md. : 1950) 1998 Nov;161(10):5607-13
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Immunization with a tumor-cell-lysate-loaded autologous-antigen-presenting-cell-based vaccine in melanoma.
Chakraborty, N G; Sporn, J R; Tortora, A F; Kurtzman, S H; Yamase, H; Ergin, M T; Mukherji, B Cancer immunology, immunotherapy : CII 1998 Sep;47(1):58-64
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Human melanoma-specific, noncytolytic CD8+ T cells that can synthesize type I cytokine.
Chakraborty, N G; Mukherji, B Cancer research 1998 Apr;58(7):1363-6
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Enhancement of cytolytic T lymphocyte precursor frequency in melanoma patients following immunization with the MAGE-1 peptide loaded antigen presenting cell-based vaccine.
Hu, X; Chakraborty, N G; Sporn, J R; Kurtzman, S H; Ergin, M T; Mukherji, B Cancer research 1996 Jun;56(11):2479-83
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Presentation of synthetic peptide antigen encoded by the MAGE-1 gene by granulocyte/macrophage-colony-stimulating-factor-cultured macrophages from HLA-A1 melanoma patients.
Yamasaki, S; Okino, T; Chakraborty, N G; Adkisson, W O; Sampieri, A; Padula, S J; Mauri, F; Mukherji, B Cancer immunology, immunotherapy : CII 1995 Apr;40(4):268-71
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Inhibition of interleukin-2 synthesis and interleukin-2 receptor alpha expression on T cells by a cell-free factor derived from a CD4+ regulatory T cell clone.
Okino, T; Chakraborty, N G; Stabach, P; Twardzik, D R; Padula, S J; Mukherji, B Clinical immunology and immunopathology 1993 Sep;68(3):256-62
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Adoptive immunotherapy with peripheral blood lymphocytes cocultured in vitro with autologous tumor cells and interleukin-2.
Sporn, J R; Ergin, M T; Robbins, G R; Cable, R G; Silver, H; Mukherji, B Cancer immunology, immunotherapy : CII 1993 Aug;37(3):175-80
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Analysis of cytolytic effector cell response in vitro against autologous human tumor cells genetically altered to synthesize interleukin-2.
Tohmatsu, A; Okino, T; Stabach, P; Padula, S J; Ergin, M T; Mukherji, B Immunology letters 1993 Jan;35(1):51-7
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Suppression of lymphokine-activated killer cell generation by tumor-infiltrating lymphocytes.
Chakraborty, N G; Sporn, J R; Pasquale, D R; Ergin, M T; Mukherji, B Clinical immunology and immunopathology 1991 Jun;59(3):407-16
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Clonal expansion of T cells following in vitro stimulation with autologous melanoma cells and interleukin-2 studied by molecular analysis of a T cell receptor.
Sivanandham, M; Chakraborty, N G; Robbins, G R; Mukherji, B Immunology letters 1991 May;28(2):155-9
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Adoptive transfer of activated human autologous macrophages results in regression of transplanted human melanoma cells in SCID mice.
Chakraborty, N G; Okino, T; Stabach, P; Padula, S J; Yamase, H; Morse, E; Sha'afi, R I; Twardzik, D R; Shultz, L J; Mukherji, B In vivo (Athens, Greece) 1991 Jan;5(6):609-14
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Suppressor function of lymphocytes activated in in vitro co-culture against autologous tumor cells and expanded in interleukin-2.
Okino, T; Chakraborty, N G; Ergin, M T; Mukherji, B In vivo (Athens, Greece) 1991 Jan;5(6):631-5
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Autologous melanoma-induced activation of regulatory T cells that suppress cytotoxic response.
Chakraborty, N G; Twardzik, D R; Sivanandham, M; Ergin, M T; Hellstrom, K E; Mukherji, B Journal of immunology (Baltimore, Md. : 1950) 1990 Oct;145(7):2359-64
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Functionally different HTLV I-infected T cell lines with the same phenotype derived from a patient with melanoma.
Sivanandham, M; Mukherji, B Immunology letters 1989 Dec;23(2):149-54
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Clonal analysis of cytotoxic and regulatory T cell responses against human melanoma.
Mukherji, B; Guha, A; Chakraborty, N G; Sivanandham, M; Nashed, A L; Sporn, J R; Ergin, M T The Journal of experimental medicine 1989 Jun;169(6):1961-76
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Imaging pattern of previously in vitro sensitized and interleukin-2 expanded autologous lymphocytes in human cancer.
Mukherji, B; Arnbjarnarson, O; Spitznagle, L A; Kalish, R I; Hoffman, J; Ergin, M T; Spencer, R P International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1988 Jan;15(4):419-27
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Activation of autoreactive cytolytic T lymphocyte clone against human melanoma by anti-T3 monoclonal antibody and autologous accessory cells.
Tatake, R J; Guha, A; Mukherji, B Cellular immunology 1987 Aug;108(1):42-52
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T-cell surface molecules involved in the induction and expression of lymphokine-activated killing of autologous and allogeneic tumor targets.
Nashed, A L; Mukherji, B Journal of clinical immunology 1987 Jul;7(4):288-93
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Cell-mediated amplification and down regulation of cytotoxic immune response against autologous human cancer.
Mukherji, B; Guha, A; Loomis, R; Ergin, M T Journal of immunology (Baltimore, Md. : 1950) 1987 Mar;138(6):1987-91
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Biodistribution of IN-111 labeled tumor sensitized autologous lymphocytes in cancer patients.
Mukherji, B; Arnbjarnarson, O; Spitznagle, L A; Hoffman, J; Ergin, M T; Spencer, R P Progress in clinical and biological research 1987 Jan;244325-34
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The use of T cell lines as probes for studies of cytotoxic anti-tumor response and its regulation in the human system.
Mukherji, B; Tatake, R J; Guha, A; Nashed, A; Ergin, M T Progress in clinical and biological research 1987 Jan;244251-8
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Suppressor cell activities in autologous human tumor systems. Suppression of tumor immunity.
Mukherji, B; Ergin, M T; Guha, A; Tatake, R T; Nashed, A L Archives of surgery (Chicago, Ill. : 1960) 1986 Dec;121(12):1404-8
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Regulation of cellular immune response against autologous human melanoma. I. Evidence for cell-mediated suppression of in vitro cytotoxic immune response.
Mukherji, B; Wilhelm, S A; Guha, A; Ergin, M T Journal of immunology (Baltimore, Md. : 1950) 1986 Mar;136(5):1888-92
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Regulation of cellular immune response against autologous human melanoma. II. Mechanism of induction and specificity of suppression.
Mukherji, B; Nashed, A L; Guha, A; Ergin, M T Journal of immunology (Baltimore, Md. : 1950) 1986 Mar;136(5):1893-8
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In vitro cytotoxicity and transplantation protection by autologous natural and activated killer cells against an in vitro transformed tumorigenic fibroblast line. A case study.
Wilhelm, S A; Mukherji, B The Journal of clinical investigation 1985 Apr;75(4):1162-8
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The role of cytoplasmic intermediates in IL 2-induced T cell growth.
Gutowski, J K; Mukherji, B; Cohen, S Journal of immunology (Baltimore, Md. : 1950) 1984 Dec;133(6):3068-74
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Spontaneous in vitro transformation of human fibroblasts.
Mukherji, B; MacAlister, T J; Guha, A; Gillies, C G; Jeffers, D C; Slocum, S K Journal of the National Cancer Institute 1984 Sep;73(3):583-93
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Clonal analysis of cytotoxic T cell response against human melanoma.
Mukherji, B; MacAlister, T J The Journal of experimental medicine 1983 Jul;158(1):240-5
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Functional hybrids between human cytotoxic T and mouse myeloma cells.
Mukherji, B; Cieplinski, W Hybridoma 1983 Jan;2(4):383-92
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Is prolactin secreted ectopically?
Molitch, M E; Schwartz, S; Mukherji, B The American journal of medicine 1981 Apr;70(4):803-7
