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Synthesis of 2-Oxoquinoline Derivatives as Dual Pim and mTORC Protein Kinase Inhibitors.
Gnawali, Giri R; Okumura, Koichi; Perez, Karolina; Gallagher, Rosa; Wulfkuhle, Julia; Petricoin, Emanuel F; Padi, Sathish Kumar Reddy; Bearss, Jeremiah; He, Zhiyong; Wang, Wei; Kraft, Andrew S Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents 2022 Jul;31(7):1154-1175
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The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer.
Singh, Neha; Ramnarine, Varune R; Song, Jin H; Pandey, Ritu; Padi, Sathish K R; Nouri, Mannan; Olive, Virginie; Kobelev, Maxim; Okumura, Koichi; McCarthy, David; Hanna, Michelle M; Mukherjee, Piali; Sun, Belinda; Lee, Benjamin R; Parker, J Brandon; Chakravarti, Debabrata; Warfel, Noel A; Zhou, Muhan; Bearss, Jeremiah J; Gibb, Ewan A; Alshalalfa, Mohammed; Karnes, R Jefferey; Small, Eric J; Aggarwal, Rahul; Feng, Felix; Wang, Yuzhuo; Buttyan, Ralph; Zoubeidi, Amina; Rubin, Mark; Gleave, Martin; Slack, Frank J; Davicioni, Elai; Beltran, Himisha; Collins, Colin; Kraft, Andrew S Nature communications 2021 Dec;12(1):7349
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"Root"ing for successful T-ALL treatment.
Padi, Sathish K R; Kraft, Andrew S Blood 2021 May;137(18):2422-2423
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EDC3 phosphorylation regulates growth and invasion through controlling P-body formation and dynamics.
Bearss, Jeremiah J; Padi, Sathish Kr; Singh, Neha; Cardo-Vila, Marina; Song, Jin H; Mouneimne, Ghassan; Fernandes, Nikita; Li, Yang; Harter, Matthew R; Gard, Jaime Mc; Cress, Anne E; Peti, Wolfgang; Nelson, Andrew Dl; Buchan, J Ross; Kraft, Andrew S; Okumura, Koichi EMBO reports 2021 Apr;22(4):e50835
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PIM Kinase Inhibitors Block the Growth of Primary T-cell Acute Lymphoblastic Leukemia: Resistance Pathways Identified by Network Modeling Analysis.
Lim, James T; Singh, Neha; Leuvano, Libia A; Calvert, Valerie S; Petricoin, Emanuel F; Teachey, David T; Lock, Richard B; Padi, Megha; Kraft, Andrew S; Padi, Sathish K R Molecular cancer therapeutics 2020 Sep;19(9):1809-1821
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PIM protein kinases regulate the level of the long noncoding RNA H19 to control stem cell gene transcription and modulate tumor growth.
Singh, Neha; Padi, Sathish K R; Bearss, Jeremiah J; Pandey, Ritu; Okumura, Koichi; Beltran, Himisha; Song, Jin H; Kraft, Andrew S; Olive, Virginie Molecular oncology 2020 May;14(5):974-990
