Education

Degree	Institution	Major
BS	Slippery Rock College	Biology
MS	Slippery Rock College	Biology
PhD	West Virginia University	Reproductive Physiology

Post-Graduate Training

Training	Institution	Specialty
Postdoctoral	Wayne State University	Reproductive Physiology

Awards

Name of Award/Honor	Awarding Organization
Top Reviewer. This awarded is given to the top 10% of reviewers for the journal, Molecular Human Reproduction	Molecular Human Reproduction

Name & Description	Category	Role	Type	Scope	Start Year	End Year
Faculty Review Board	Advisory Committee	member	UConn Health	Local	2019
Reproductive Endocrinology and Biology	Editorial Board	Section Head (i.e. Associate Editor	External	International	2019
Journal of Ovarian Research	Editorial Board	Section Head (i.e. Associate Editor)	External	International	2019
External Advisory Board PO1 Grant: “Ovulation and Luteal Function … women”	Professional/Scientific Journal	Member	External	National	2019
IRB Scientific Review Committee	Advisory Committee	member	UConn Health	University	2019
U54 Review Panel	Study Section	Chair	External	National	2011	2012
Heritage Committee; Society for the Study of Reproduction	Advisory Committee	Member	External	National	2011
Search Committee for Cell Biology	Advisory Committee	Chairman	UConn Health	University	2010	2010
Women’s Reproductive Health Panel (ZHD1 DSR-L)	Study Section	Chairman	External	National	2009	2009
U54 Grant review Panel	Study Section	Member	External	National	2009	2011
Challenge Grant Review Panel (ZRG1-EMNR-C58)	Study Section	Member	Other	National	2009	2009
Reproduction, Andrology and Gynecology SS	Study Section	Chair	External	National	2008	2010
Faculty Review Board	Advisory Committee	Member	UConn Health	University	2008
Conflict of Interest in Research Management Committee	Research Committee	Member	UConn Health	University	2008
Ethics Stem Cell Research Committee	Advisory Committee	Member	UConn Health	University	2006	2007
Institution Review Board	Advisory Committee	Vice-Chair Panel 3	UConn Health	University	2006	2010
Human Subjects Protection Office Executive Council	Advisory Committee	Member	UConn Health	University	2006	2010
Institution Review Board	Advisory Committee	Chair Panel 4 (Stem Cell Panel)	UConn Health	University	2006	2008
Nuclear Receptor Signaling	Editorial Board	Reviewer	External	National	2005
Reproduction, Andrology and Gynecology SS	Study Section	Grant Reviewer	External	National	2005	2010
Special NIH Review Panel	Study Section	Member	External	National	2003	2003
Dental School Council	Education Committee	Member	UConn Health	University	2002	2007
Endocrinology	Editorial Board	Member	External	National	2001	2005
Reproductive Endocrinology and Biology	Editorial Board	Member	External	National	2001
REB Study Section	Study Section	Ad Hoc Grant Reviewer	External	National	2001	2001
Special NIH Review Panel	Study Section	Chairman	External	National	2001	2001
U54 Review Panel	Study Section	Discussion Leader	External	National	2001	2001
Biology of Reproduction	Editorial Board	Member	External	National	2000	2004
Ob/Gyn Research Committee - University of Connecticut Health Center	Research Committee	Member	UConn Health	University	1999	2001
MRC-Canada	Professional/Scientific Organization	Grant Reviewer	External	International	1998	1998
Scientific Program Committee: Society for Study of Reproduction Annual Meetings	Advisory Committee	Member	External	National	1998	1999
NIH-Site Visit Team: Biol Pgm Projects	Study Section	Grant Reviewer	External	National	1997	1999
Lab Services Work Redesign Team	Advisory Committee	Member	UConn Health	University	1997	1997
Senior Appointments and Promotion Committee	Advisory Committee	Member	UConn Health	University	1996	2007
Developmental Biology Graduate Program	Advisory Committee	Director	UConn Health	University	1995	1997
Endocrine Society's Animal Welfare	Advisory Committee	State Chair	External	State	1995	1995
Scientific Program Committee: Society for Gynecologic Investigation Annual Meetings	Professional/Scientific Organization	Member	External	National	1994	1999
Mini-Course Committee - Devel Biol Grad Pgm	Education Committee	Member	UConn Health	University	1994	1995
Senior Appointments and Promotion Committee	Advisory Committee	Member	UConn Health	University	1993	1994
Design Committee for the "New" Research Bld	Advisory Committee	Member	UConn Health	University	1992	1993
Combined Admissions Committee for the Graduate Program - Developmental Biology Rep.	Advisory Committee	Member	UConn Health	University	1991	1994
Animal Care Committee - University of Connecticut Health Center	Advisory Committee	Member	UConn Health	University	1990	1994
Institutional Review Board - University of Connecticut Health Center	Advisory Committee	Member	UConn Health	University	1987	1994
Reproduction	Professional/Scientific Journal	Ad Hoc Reviewer	External	National
Fertility and Sterility	Professional/Scientific Journal	Ad Hoc Reviewer	External	National
Am J.Physiol: Endocrology and Metabolism	Professional/Scientific Journal	Ad Hoc Reviewer	External	National
Endocrine	Professional/Scientific Journal	Ad Hoc Reviewer	External	National
Prostaglandin	Professional/Scientific Journal	Ad Hoc Reviewer	External	National
Developmental Biology	Professional/Scientific Journal	Ad Hoc Reviewer	External	National
BioTechiques	Professional/Scientific Journal	Ad Hoc Reviewer	External	National
Molecular and Cellular Endocrinology	Professional/Scientific Journal	Ad Hoc Reviewer	External	National
National Science Foundation	Professional/Scientific Organization	Grant Reviewer	External	National
March of Dimes	Professional/Scientific Organization	Grant Reviewer	External	National
USDA	Professional/Scientific Organization	Grant Reviewer	External	National
Lalor Foundation	Professional/Scientific Organization	Grant Reviewer	External	National
The Endocrine Society	Professional/Scientific Organization	Member	External	National
Society for the Study of Reproduction	Professional/Scientific Organization	Member	External	National
Grade Inflation Committee - Loyola University of Chicago	Advisory Committee	Member	External	University
University Research Committee - Loyola University	Advisory Committee	Member	External	University
Graduate Program Committee-Chairman-Loyola University	Advisory Committee	Member	External	University
Radiation Safety Committee-Loyola University	Advisory Committee	Member	External	University
Animal Care Committee-Loyola University	Advisory Committee	Member	External	University

Hormonal control of ovarian follicular growth and atresia; cellular and molecular mechanisms involved in apoptosis; Characterization of a novel membrane receptor for progesterone (PGRMC1) including the elucidation of its signal transduction pathway. Studies included identification of proteins that bind PGRMC1 using proteomics, protein-protein interaction assays and genetic approaches to deplete or enhance expression. Additional studies are being conducted on PGRMC1's role in modulating the sensitivity of ovarian cancer cells to chemotherapy both in vitro and in vivo.

Expression and structural features of a novel membrane receptor for progesterone (PGRMC1). The panel at the left shows the different domains of PGRMC1. However, the proteins that bind PGRMC1 and are presumably involved in ligand activated signal transduction have not been identified. The panel at the right shows the expression of PGRMC1 within the immature rat ovary.

Not accepting students for Lab Rotations at this time

Journal Articles

Book Chapters

Book Sections

Conference Papers

Reviews

Short Surveys

Title or Abstract	Type	Sponsor/Event	Date/Year	Location
Sumoylation and Nuclear Action of Progesterone Receptor Membrane Component-1	Talk	7th International Meeting on Rapid Responses to Steroid Hormones	2011	Crete, Greece
Progesterone signaling in ovarian cancer	Talk	FASEB Summer Research Conference, The Physiology of Integrated Nuclear and Extranuclear Steroid Sign	2010	Snowmass, CO
Progesterone receptor membrane component-1 in regulating normal and cancerous ovarian cells	Talk	28th Annual Ottawa Reproductive Biology Workshop	2010	Toronto, Ontario, Canada
Progesterone Membrane Receptor Component 1 as a Mediator of Progesterone’s Actions in Normal and Neoplastic Ovarian Cells	Talk	5th Annual Gilbert S. Greenwald Symposium on Reproduction	2008	Kansas City, KS
Identification of a Membrane Receptor Complex That Mediates Progesterone’s Anti-apoptotic Action	Talk	26th Annual Symposium in Reproductive Sciences and Women’s Health	2007	Lexington, KY
Identification of a Novel Membrane Receptor Complex that Mediates Progesterone’s Anti-Apoptotic Action in Granulosa and Luteal Cells	Talk	23rd Annual Ottawa Reproductive Biology Workshop	2005	Toronto, Ontario, Canada
Identification of a Putative Progesterone Receptor Complex and Signal Transduction pathway that Mediate Progesterone’s Non-genomic Action in Granulosa Cells	Talk	38th Meeting of the Society for the Study of Reproduction	2005	Quebec City, Quebec, Canada
Basic FGF and Ovarian Apoptosis	Talk	International Symposium on Apoptosis	2003	Luxembourg
Rapid Actions of Progesterone on Granulosa Cells	Talk	III International Meeting on Rapid Responses to Steroid Hormones	2003	Florence, Italy
The Quest For The Elusive Membrane Progesterone Receptor	Talk	Gabriel Bialy State-of-the-Art Lecture in Reproductive Physiology	2003	Carbondale, IL
Progesterone Regulation of Granulosa Cell Viability Through Membrane-initiated Mechanism	Talk	36th Meeting of the Society for the Study of Reproduction	2003	Cincinnati, OH
Progesterone and Apoptosis	Talk	International Congress on Hormonal Steroids and Hormones and Cancer	2002	Fukuoka, Japan
Extracellular matrix and cell-cell contact as regulators of ovarian surface epithelial cell mitosis and apoptosis	Talk	Serono Symposium: XIII Ovarian Workshop	2000	Madison, WI
IP3R3 Expression and ROSE-179 cell Apoptosis	Talk	Serono Symposium: XII Ovarian Workshop	1998	Houston, TX
Placing progesterone in the apoptotic pathway	Lecture	Postgraduate Course: Apoptosis in the Reproductive System	1997	San Diego, CA
Cell contact inhibits granulosa cell and ovarian epithelial cell apoptosis	Talk	Serono Symposium: Cell Death in Reproductive Physiology	1996	Chicago, IL
Steroids as negative regulators of granulosa cell proliferation and differentiation	Talk	Schering Symposium: Cell Culture Models in Pharmaceutical Research	1993	Berlin, Germany
Regulation of follicular development	Talk	NIH Conference: Ovarian Follicular Selection and Atresia	1992	Bethesda, MD
Model systems used to study follicular atresia	Talk	IX Ovarian Workshop: Ovarian Cell Interactions	1992	Chapel Hill, NC
Alterations within oocytes which predicate abnormal preimplantation development	Talk	VII European Sterility Congress Symposium on Post Conception Failures in Reproduction	1984	Monte Carlo
Control of ovarian function in vitro	Talk	Serono Symposium: Development and Function of the Reproductive Tissues	1984	Rehovet, Israel