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Vishwanatha K Rao, Ph.D.Assistant Professor in Residence, Department of Neuroscience
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Dr. Kurutihalli Vishwanatha is a protein biochemist with experience managing multiple research projects in the areas of fungal proteases, secretory pathway of neuroendocrine proteins and Rho-GEF signaling complexes.
Education
Post-Graduate Training
Awards
| Degree | Institution | Major |
|---|---|---|
| BSc | University of Agricultural Sciences | Agriculture |
| MSc | University of Agricultural Sciences | Genetics and Plant Breeding |
| PhD | University of Mysore | Biochemistry (Fungal Acid Proteases) |
Post-Graduate Training
| Training | Institution | Specialty |
|---|---|---|
| Fellowship | University of Mysore | Graduate Fellowship, Central Food Technological Research Institute |
| Postdoctoral | UConn School of Medicine | Postdoctoral Fellow, Biochemical and Structural Characterization of PAM, and Amidating Enzyme |
Awards
| Name of Award/Honor | Awarding Organization |
|---|---|
| Graduate Fellowship | CSIR-India |
| Certificate of Merit for Being Among the Top 5 Percent of Selected Candidates for the Graduate Fellowship | CSIR-India |
| Name & Description | Category | Role | Type | Scope | Start Year | End Year |
|---|---|---|---|---|---|---|
| Neuroscience Department Annual Retreat-2019 | Workshop/Conference | Co-Organizer | UConn Health | University | 2019 | |
| BMC Biochemistry Journal of Biomedical Sciences Molecular and Cellular Biochemistry Neuropeptides | Professional/Scientific Journal | Reviewer | External | International | 2017 | 2017 |
Neuropeptide amidation
Rho-GEF signalling
Synaptogenisis
Journal Articles
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Multiple roles for peptidylglycine α-amidating monooxygenase in the response to hypoxia.
Journal of cellular physiology 2021 Jun;
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Role of Kalirin and mouse strain in retention of spatial memory training in an Alzheimer's disease model mouse line.
Neurobiology of aging 2020 Nov;9569-80
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A pH-sensitive luminal His-cluster promotes interaction of PAM with V-ATPase along the secretory and endocytic pathways of peptidergic cells.
Journal of cellular physiology 2018 Oct;
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The endocytic pathways of a secretory granule membrane protein in HEK293 cells: PAM and EGF traverse a dynamic multivesicular body network together.
European journal of cell biology 2017 Aug;96(5):407-417
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O-Glycosylation of a Secretory Granule Membrane Enzyme Is Essential for Its Endocytic Trafficking.
The Journal of biological chemistry 2016 Mar;2919835-50
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An N-terminal Amphipathic Helix Binds Phosphoinositides and Enhances Kalirin Sec14 Domain-mediated Membrane Interactions.
The Journal of biological chemistry 2015 Apr;290(21):13541-55
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A histidine-rich linker region in peptidylglycine α-amidating monooxygenase has the properties of a pH sensor.
The Journal of biological chemistry 2014 May;289(18):12404-20
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Nonenzymatic domains of Kalirin7 contribute to spine morphogenesis through interactions with phosphoinositides and Abl.
Molecular biology of the cell 2014 Mar;25(9):1458-71
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Structural organization of the nine spectrin repeats of Kalirin.
Biochemistry 2012 Jul;51(28):5663-73
Book Chapters
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Neuropeptide Synthesis and Storage
Reference Module in Neuroscience and Biobehavioral Psychology 2017 Oct;
| Title or Abstract | Type | Sponsor/Event | Date/Year | Location |
|---|---|---|---|---|
| Peptidylglycine alpha-Amidating Monooxygenase (PAM) interacts with V-ATPase and alters its response to hypoxia | Poster | International Hypoxia Meeting | 2018 | University of Oxford, UK |
| Expression of Peptidylglycine alpha-Amidating Monooxygenase (PAM) alters the response of pituitary cells to hypoxia | Poster | International Hypoxia Meeting | 2018 | University of Oxford, UK |
| Exosomes Derived from Mouse Pituitary Corticotrope Cells Reveal Presence of PAM and V-ATPase | Poster | Innovation Fellows Research Day | 2018 | UConn Health, Farmington USA |
| Endocytosed PAM, MPR and EGF traverse a dynamic multivesicular body network together | Poster | American Society of Cell Biology | 2017 | Philadelphia, PA |
| Molecular determinants of Vacuolar-type H+ ATPase driven luminal acidification | Poster | SACNAS-National Diversity in STEM conference | 2017 | Salt Lake city, Utah |