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PharmVar Tutorial on CYP2D6 Structural Variation Testing and Recommendations on Reporting.
Turner, Amy J; Nofziger, Charity; Ramey, Bronwyn E; Ly, Reynold C; Bousman, Chad A; Agúndez, José A G; Sangkuhl, Katrin; Whirl-Carrillo, Michelle; Vanoni, Simone; Dunnenberger, Henry M; Ruaño, Gualberto; Kennedy, Martin A; Phillips, Michael S; Hachad, Houda; Klein, Teri E; Moyer, Ann M; Gaedigk, Andrea Clinical pharmacology and therapeutics 2023 Sep;
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Contrasting ABCB1 pharmacogenetics and psychotropic responses in child and adolescent psychiatry: a case comparison.
Kalla, Pragya; Namerow, Lisa B; Walker, Sophia A; Ruaño, Gualberto; Malik, Salma Pharmacogenomics 2023 Feb;24(3):131-139
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Subanalysis of the CYP-GUIDES Trial: CYP2D6 Functional Stratification and Operational Timeline Selection.
Ruaño G, Tortora J, Robinson S, Baker S, Holford T, Winokur A, Goethe JW Psychiatry Res 297 (2021)113571 2021 Mar;297113571
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Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6, OPRM1, and COMT Genotypes and Select Opioid Therapy.
Crews, Kristine R; Monte, Andrew A; Huddart, Rachel; Caudle, Kelly E; Kharasch, Evan D; Gaedigk, Andrea; Dunnenberger, Henry M; Leeder, J Steven; Callaghan, John T; Samer, Caroline Flora; Klein, Teri E; Haidar, Cyrine E; Van Driest, Sara L; Ruano, Gualberto; Sangkuhl, Katrin; Cavallari, Larisa H; Müller, Daniel J; Prows, Cynthia A; Nagy, Mohamed; Somogyi, Andrew A; Skaar, Todd C Clinical pharmacology and therapeutics 2021 Jan;
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Assessment of the clinical utility of pharmacogenetic guidance in a comprehensive medication management service.
Rodríguez-Escudero, Idaliz; Cedeño, Julio A; Rodríguez-Nazario, Ileana; Reynaldo-Fernández, Gledys; Rodríguez-Vera, Leyanis; Morales, Niretzy; Jiménez-Vélez, Braulio; Ruaño, Gualberto; Duconge, Jorge Journal of the American College of Clinical Pharmacy : JACCP 2020 Sep;3(6):1028-1037
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Implementing a pharmacogenetic-driven algorithm to guide dual antiplatelet therapy (DAPT) in Caribbean Hispanics: protocol for a non-randomised clinical trial.
Hernandez-Suarez, Dagmar F; Melin, Kyle; Marin-Maldonado, Frances; Nunez, Hector J; Gonzalez, Ariel F; Gonzalez-Sepulveda, Lorena; Rivas-Tumanyan, Sona; Naik, Hetanshi; Ruaño, Gualberto; Scott, Stuart A; Duconge, Jorge BMJ open 2020 Aug;10(8):e038936
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Clinical database of the CYP-guides trial: An open data resource on psychiatric hospitalization for severe depression.
Tortora, Joseph; Robinson, Saskia; Baker, Seth; Ruaño, Gualberto Data in brief 2020 Jun;30105457
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Pharmacogenomics: an Update for Child and Adolescent Psychiatry.
Namerow, Lisa B; Walker, Sophia A; Loftus, Mirela; Bishop, Jeffrey R; Ruaño, Gualberto; Malik, Salma Current psychiatry reports 2020 May;22(5):26
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Pharmacogenetics and the Personalization of Pain Management: A Potential Role in Precision Opioid Treatment
Kost Jonathan, Ruaño Gualberto Connecticut Medicine, 84 (1): 13-18, 2020 2020 Jan;
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PharmVar GeneFocus: CYP2D6.
Nofziger, Charity; Turner, Amy J; Sangkuhl, Katrin; Whirl-Carrillo, Michelle; Agúndez, José A G; Black, John L; Dunnenberger, Henry M; Ruano, Gualberto; Kennedy, Martin A; Phillips, Michael S; Hachad, Houda; Klein, Teri E; Gaedigk, Andrea Clinical pharmacology and therapeutics 2019 Dec;107(1):154-170
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Results of the CYP-GUIDES randomized controlled trial: Total cohort and primary endpoints.
Ruaño, Gualberto; Robinson, Saskia; Holford, Theodore; Mehendru, Raveen; Baker, Seth; Tortora, Joseph; Goethe, John W Contemporary clinical trials 2019 Dec;89105910
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Pharmacogenetic clinical decision support for psychiatric hospitalization: Design of the CYP-GUIDES randomized controlled trial.
Ruaño, Gualberto; Holford, Theodore; Seip, Richard L; Goethe, John W; Mehendru, Raveen Contemporary clinical trials 2019 Aug;8327-36
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Ethnogeographic prevalence and implications of the 677C>T and 1298A>C MTHFR polymorphisms in US primary care populations.
Graydon, James S; Claudio, Karla; Baker, Seth; Kocherla, Mohan; Ferreira, Mark; Roche-Lima, Abiel; Rodríguez-Maldonado, Jovaniel; Duconge, Jorge; Ruaño, Gualberto Biomarkers in medicine 2019 Jun;13(8):649-661
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Fundamental Considerations for Genetically-Guided Pain Management with Opioids Based on CYP2D6 and OPRM1 Polymorphisms.
Ruano, Gualberto; Kost, Jonathan A Pain physician 2018 Nov;21(6):E611-E621
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VEGFA GENE variation influences hallucinations and frontotemporal morphology in psychotic disorders: a B-SNIP study.
Lizano, Paulo; Lutz, Olivia; Ling, George; Padmanabhan, Jaya; Tandon, Neeraj; Sweeney, John; Tamminga, Carol; Pearlson, Godfrey; Ruaño, Gualberto; Kocherla, Mohan; Windemuth, Andreas; Clementz, Brett; Gershon, Elliot; Keshavan, Matcheri Translational psychiatry 2018 Oct;8(1):215
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Warfarin Anticoagulation Therapy in Caribbean Hispanics of Puerto Rico: A Candidate Gene Association Study.
Claudio-Campos, Karla; Labastida, Aurora; Ramos, Alga; Gaedigk, Andrea; Renta-Torres, Jessicca; Padilla, Dariana; Rivera-Miranda, Giselle; Scott, Stuart A; Ruaño, Gualberto; Cadilla, Carmen L; Duconge-Soler, Jorge Frontiers in pharmacology 2017 Jan;8347
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Admixture and ethno-specific alleles: missing links for global pharmacogenomics.
Duconge, Jorge; Ruaño, Gualberto Pharmacogenomics 2016 Sep;17(14):1479-82
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Multivariate Genetic Correlates of the Auditory Paired Stimuli-Based P2 Event-Related Potential in the Psychosis Dimension From the BSNIP Study.
Mokhtari, Mohammadreza; Narayanan, Balaji; Hamm, Jordan P; Soh, Pauline; Calhoun, Vince D; Ruaño, Gualberto; Kocherla, Mohan; Windemuth, Andreas; Clementz, Brett A; Tamminga, Carol A; Sweeney, John A; Keshavan, Matcheri S; Pearlson, Godfrey D Schizophrenia bulletin 2016 May;42(3):851-62
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Practical interpretation of CYP2D6 haplotypes: Comparison and integration of automated and expert calling.
Ruaño, Gualberto; Kocherla, Mohan; Graydon, James S; Holford, Theodore R; Makowski, Gregory S; Goethe, John W Clinica chimica acta; international journal of clinical chemistry 2016 May;4567-14
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Comparative physiogenomic analyses of weight loss in response to 2 modes of bariatric surgery: demonstration with candidate neuropsychiatric and cardiometabolic genes.
Seip, Richard L; Papasavas, Pavlos; Stone, Andrea; Thompson, Stephen; Ng, Janet; Tishler, Darren S; Ruaño, Gualberto Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2016 Feb;12(2):369-77
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A Novel Admixture-Based Pharmacogenetic Approach to Refine Warfarin Dosing in Caribbean Hispanics.
Duconge, Jorge; Ramos, Alga S; Claudio-Campos, Karla; Rivera-Miranda, Giselle; Bermúdez-Bosch, Luis; Renta, Jessicca Y; Cadilla, Carmen L; Cruz, Iadelisse; Feliu, Juan F; Vergara, Cunegundo; Ruaño, Gualberto PloS one 2016 Jan;11(1):e0145480
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Pharmacogenetics of drug-metabolizing enzymes in US Hispanics.
Claudio-Campos, Karla; Duconge, Jorge; Cadilla, Carmen L; Ruaño, Gualberto Drug metabolism and personalized therapy 2015 Jun;30(2):87-105
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Genetic Sources of Subcomponents of Event-Related Potential in the Dimension of Psychosis Analyzed From the B-SNIP Study.
Narayanan, Balaji; Ethridge, Lauren E; O'Neil, Kasey; Dunn, Sabra; Mathew, Ian; Tandon, Neeraj; Calhoun, Vince D; Ruaño, Gualberto; Kocherla, Mohan; Windemuth, Andreas; Clementz, Brett A; Tamminga, Carol A; Sweeney, John A; Keshavan, Matcheri S; Pearlson, Godfrey D The American journal of psychiatry 2015 May;172(5):466-78
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Pharmacogenetic Testing for Analgesic Adverse Effects: Pediatric Case Series.
Manworren, Renee C B; Jeffries, Lauren; Pantaleao, Ashley; Seip, Richard; Zempsky, William T; Ruaño, Gualberto The Clinical journal of pain 2015 Mar;32109-15
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Pharmacogenetic association study of warfarin safety endpoints in Puerto Ricans.
Valentín, Isa I; Rivera, Giselle; Nieves-Plaza, Mariely; Cruz, Iadelisse; Renta, Jessica Y; Cadilla, Carmen L; Feliu, Juan F; Seip, Richard L; Ruaño, Gualberto; Duconge, Jorge Puerto Rico health sciences journal 2014 Sep;33(3):97-104
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Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia.
Meda, Shashwath A; Ruaño, Gualberto; Windemuth, Andreas; O'Neil, Kasey; Berwise, Clifton; Dunn, Sabra M; Boccaccio, Leah E; Narayanan, Balaji; Kocherla, Mohan; Sprooten, Emma; Keshavan, Matcheri S; Tamminga, Carol A; Sweeney, John A; Clementz, Brett A; Calhoun, Vince D; Pearlson, Godfrey D Proceedings of the National Academy of Sciences of the United States of America 2014 May;111(19):E2066-75
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Personalizing public health in the medical laboratory: the interplay of microarrays and physiological genomics.
Ruaño, Gualberto MLO: medical laboratory observer 2013 Dec;45(12):36-7
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Length of psychiatric hospitalization is correlated with CYP2D6 functional status in inpatients with major depressive disorder.
Ruaño, Gualberto; Szarek, Bonnie L; Villagra, David; Gorowski, Krystyna; Kocherla, Mohan; Seip, Richard L; Goethe, John W; Schwartz, Harold I Biomarkers in medicine 2013 Jun;7(3):429-39
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Development of a pharmacogenetic-guided warfarin dosing algorithm for Puerto Rican patients.
Ramos, Alga S; Seip, Richard L; Rivera-Miranda, Giselle; Felici-Giovanini, Marcos E; Garcia-Berdecia, Rafael; Alejandro-Cowan, Yirelia; Kocherla, Mohan; Cruz, Iadelisse; Feliu, Juan F; Cadilla, Carmen L; Renta, Jessica Y; Gorowski, Krystyna; Vergara, Cunegundo; Ruaño, Gualberto; Duconge, Jorge Pharmacogenomics 2012 Dec;13(16):1937-50
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Validation of candidate genes associated with cardiovascular risk factors in psychiatric patients.
Windemuth, Andreas; de Leon, Jose; Goethe, John W; Schwartz, Harold I; Woolley, Stephen; Susce, Margaret; Kocherla, Mohan; Bogaard, Kali; Holford, Theodore R; Seip, Richard L; Ruaño, Gualberto Progress in neuro-psychopharmacology & biological psychiatry 2012 Mar;36(2):213-9
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Prediction of warfarin dose reductions in Puerto Rican patients, based on combinatorial CYP2C9 and VKORC1 genotypes.
Valentin, Isa Ivette; Vazquez, Joan; Rivera-Miranda, Giselle; Seip, Richard L; Velez, Meredith; Kocherla, Mohan; Bogaard, Kali; Cruz-Gonzalez, Iadelisse; Cadilla, Carmen L; Renta, Jessica Y; Feliu, Juan F; Ramos, Alga S; Alejandro-Cowan, Yirelia; Gorowski, Krystyna; Ruaño, Gualberto; Duconge, Jorge The Annals of pharmacotherapy 2012 Feb;46(2):208-18
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Mechanisms of statin-induced myalgia assessed by physiogenomic associations.
Ruaño, Gualberto; Windemuth, Andreas; Wu, Alan H B; Kane, John P; Malloy, Mary J; Pullinger, Clive R; Kocherla, Mohan; Bogaard, Kali; Gordon, Bruce R; Holford, Theodore R; Gupta, Ankur; Seip, Richard L; Thompson, Paul D Atherosclerosis 2011 Oct;218(2):451-6
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Automated extraction of pain symptoms: a natural language approach using electronic health records.
Dave AD, Ruaño G, Kost J, Wang X. Pain Physician, 25 (2): E245-E254, 2022
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Comparison of epidemiological characteristics of COVID-19 patients in Vietnam.
Ha TH, Ruano G, Lewis J. medRxiv. 2020 Jan 1.
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Contrasting ABCB1 pharmacogenetics and psychotropic responses in child and adolescent psychiatry: a case comparison.
Kalla P, Namerow LB, Walker S, Ruaño G, Malik S Pharmacogenomics
DOI: 10.2217/pgs-2022-0120 PMID: 36727491
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Coronavirus Disease 2019 in Vietnam: A Model of Early and Decisive Containment.
Ha T, Schensul S, Ruaño G, Ngo A. Asian Journal of Research in Infectious Diseases. 2020 Jun 5:24-7.
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Ethnic variation in weight loss, but not co-morbidity remission, after laparoscopic gastric banding and Roux-en-Y gastric bypass.
Ng, Janet; Seip, Richard; Stone, Andrea; Ruano, Gualberto; Tishler, Darren; Papasavas, Pavlos Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 11(1):94-100
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Pharmacogenetic Clinical Decision Support in Patients with Multi-Drug Regimens.
Duconge J, Ruaño G. Current Trends in Clinical & Medical Sciences, 3 (2): 1-2, 2022 [DOI: 10.33552/CTCMS.2022.03.000560]
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Subanalysis of the CYP-GUIDES Trial: CYP2D6 Functional Stratification and Operational Timeline Selection.
Ruaño G, Tortora J, Robinson S, Baker S, Holford T, Winokur A, Goethe JW. Psychiatry Research. 2021 Mar 1;297:113571.
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Translating the human genome to manage pediatric postoperative pain.
Manworren, Renee C B; Ruaño, Gualberto; Young, Erin; St Marie, Barbara; McGrath, Jacqueline M Journal of pediatric surgical nursing 4(1):28-39