Faculty Directory › UConn Health

Vanessa M. Scanlon, Ph.D.

Assistant Professor, Center for Regenerative Medicine and Skeletal Biology


Academic Office Location: Center for Regenerative Medicine and Skeletal Biology UConn Health 263 Farmington Avenue Farmington, CT 06030-3705
Phone:	860-679-3702
Website(s):	Skeletal Biology and Regeneration Graduate Program

Education & Training
Research
Lab Rotations
Publications

Education

Degree	Institution	Major
B.S.	University of Connecticut	Diagnostics Genetic Sciences
B.S.	University of Connecticut	Molecular Cell Biology
Ph.D.	UConn Health	Biomedical Science

Degree

Institution

Major

B.S.

University of Connecticut

Diagnostics Genetic Sciences

B.S.

University of Connecticut

Molecular Cell Biology

Ph.D.

UConn Health

Biomedical Science

Currently, I work on understanding extrinsic mechanisms that underly hematopoietic progenitor cell fate decisions. I have developed a novel method for time-lapse microscopy of bipotent progenitors dividing and committing to two potential lineages. I'm also interested in developing 3D engineered in vitro cell culture models to further investigate spatial regulation between cells of the bone marrow microenvironment.

Accepting Lab Rotation Students: Summer 2022, Fall 2022, and Spring 2023

Journal Articles

Current understanding of human megakaryocytic-erythroid progenitors and their fate determinants.
Kwon, Nayoung; Thompson, Evrett N; Mayday, Madeline Y; Scanlon, Vanessa; Lu, Yi-Chien; Krause, Diane S Current opinion in hematology 2021 Jan;28(1):28-35
Low iron promotes megakaryocytic commitment of megakaryocytic-erythroid progenitors in humans and mice.
Xavier-Ferrucio, Juliana; Scanlon, Vanessa; Li, Xiuqi; Zhang, Ping-Xia; Lozovatsky, Larisa; Ayala-Lopez, Nadia; Tebaldi, Toma; Halene, Stephanie; Cao, Chang; Fleming, Mark D; Finberg, Karin E; Krause, Diane S Blood 2019 Oct;134(18):1547-1557
Epithelial (E)-Cadherin is a Novel Mediator of Platelet Aggregation and Clot Stability.
Scanlon, Vanessa M; Teixeira, Alexandra M; Tyagi, Tarun; Zou, Siying; Zhang, Ping-Xia; Booth, Carmen Jane; Kowalska, M Anna; Bao, Jialing; Hwa, John; Hayes, Vincent; Marks, Michael S; Poncz, Mortimer; Krause, Diane S Thrombosis and haemostasis 2019 May;119(5):744-757
Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair.
Scanlon, Vanessa; Soung, Do Yu; Adapala, Naga Suresh; Morgan, Elise; Hansen, Marc F; Drissi, Hicham; Sanjay, Archana PloS one 2015 Jan;10(9):e0138194
Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy.
Adapala, Naga Suresh; Holland, Danielle; Scanlon, Vanessa; Barbe, Mary F; Langdon, Wallace Y; Tsygankov, Alexander Y; Lorenzo, Joseph A; Sanjay, Archana Bone 2014 Jul;671-9
Establishment of human cell type-specific iPS cells with enhanced chondrogenic potential.
Guzzo, Rosa M; Scanlon, Vanessa; Sanjay, Archana; Xu, Ren-He; Drissi, Hicham Stem cell reviews 2014 Jun;10(6):820-9
Retroelement demethylation associated with abnormal placentation in Mus musculus x Mus caroli hybrids.
Brown, Judith D; Piccuillo, Vanessa; O'Neill, Rachel J Biology of reproduction 2012 Mar;86(3):88
Serum protein-bound carbohydrates for following the course of disease in patients with metastatic breast carcinoma.
Waalkes, T P; Mrochek, J E; Dinsmore, S R; Tormey, D C Journal of the National Cancer Institute 1978 Sep;61(3):703-7
MRTFA: A critical protein in normal and malignant hematopoiesis and beyond.
Reed, Fiona; Larsuel, Shannon T; Mayday, Madeline Y; Scanlon, Vanessa; Krause, Diane S The Journal of biological chemistry 296100543