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Vanessa M. Scanlon, PhDAssistant Professor, Regenerative Medicine and Skeletal Biology
Pronouns:
She/Her
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Education
| Degree | Institution | Major |
|---|---|---|
| BS | University of Connecticut | Diagnostics Genetic Sciences |
| BS | University of Connecticut | Molecular Cell Biology |
| PhD | UConn Health | Biomedical Science |
Our lab works to understand extrinsic mechanisms that underlie hematopoietic progenitor cell fate decisions and might be useful targets for novel cell therapies. We utilize long-term time-lapse and high-content microscopy of hematopoietic progenitors dividing and committing to mature blood cell lineages. We're also interested in developing 3D engineered ex vivo cell culture models to further investigate spatial regulation between cells of the bone marrow microenvironment.
Contact Dr. Scanlon regarding availability for Spring 2027 rotations.
Journal Articles
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Self-sustaining media-reconstituted GelMA bioink supports printable hematopoietic cultures.
Biomaterials science 2026 May;14(10):2701-2717
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Senolytic treatment induces oligodendrocyte dysfunction and demyelination in the corpus callosum.
Proceedings of the National Academy of Sciences of the United States of America 2026 Mar;123(12):e2524897123
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Building a transparent and functional laboratory culture: guidelines for creating a Laboratory Handbook for principal investigators.
Experimental hematology 2025 Nov;151105265
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Proteoglycan-4 (PRG4) serum concentration is lower in aged mice, and genetic deficiency impacts survival probability, blood parameters, and bone during aging.
GeroScience 2025 Jun;
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Assay optimization for the objective quantification of human multilineage colony-forming units.
Experimental hematology 2023 Aug;12436-44.e3
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Multiparameter analysis of timelapse imaging reveals kinetics of megakaryocytic erythroid progenitor clonal expansion and differentiation.
Scientific reports 2022 Sep;12(1):16218
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Current understanding of human megakaryocytic-erythroid progenitors and their fate determinants.
Current opinion in hematology 2021 Jan;28(1):28-35
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Low iron promotes megakaryocytic commitment of megakaryocytic-erythroid progenitors in humans and mice.
Blood 2019 Oct;134(18):1547-1557
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Epithelial (E)-Cadherin is a Novel Mediator of Platelet Aggregation and Clot Stability.
Thrombosis and haemostasis 2019 May;119(5):744-757
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Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair.
PloS one 2015 Jan;10(9):e0138194
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Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy.
Bone 2014 Jul;671-9
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Establishment of human cell type-specific iPS cells with enhanced chondrogenic potential.
Stem cell reviews 2014 Jun;10(6):820-9
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Retroelement demethylation associated with abnormal placentation in Mus musculus x Mus caroli hybrids.
Biology of reproduction 2012 Mar;86(3):88
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Serum protein-bound carbohydrates for following the course of disease in patients with metastatic breast carcinoma.
Journal of the National Cancer Institute 1978 Sep;61(3):703-7
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MRTFA: A critical protein in normal and malignant hematopoiesis and beyond.
The Journal of biological chemistry 296100543