Photo of Leia  Shuhaibar, Ph.D.

Leia Shuhaibar, Ph.D.

Assistant Professor, Department of Cell Biology
Academic Office Location:
Cell Biology, E-6029
UConn Health
263 Farmington Avenue
Farmington, CT 06030-3636
Phone: 860-679-2677

B.S.University of Zulia (Universidad del Zulia)Biology
M.S.Florida Institute of TechnologyBiological Science - Cell and Molecular
Ph.D.University of Connecticut Health CenterBiomedical Sciences - Cell Biology

Post-Graduate Training
PostdoctoralUniversity of Connecticut Health CenterPostdoctoral Fellow

Name of Award/HonorAwarding Organization
Poster award, 1st place. 31st Annual graduate student research day. University of Connecticut Health Center. Farmington, ConnecticutUniversity of Connecticut Health Center
Honorific Mention for Undergraduate Thesis.University of Zulia. Dept of Biology. Maracaibo, Venezuela
Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
Society for the Study of Reproduction (SSR)Professional/Scientific OrganizationMemberExternalNational2016

Journal Articles

Book Chapters

  • Preparing for fertilization: Intercellular signals for oocyte maturation
    Shuhaibar, L.C., Carroll, D.J., and Jaffe, L.A. Reproductive and Developmental Strategies 2018 Jan;535-548
Title or AbstractTypeSponsor/EventDate/YearLocation
FGF-inhibition of NPR2-mediated Cyclic GMP Production in Growth Plate Chondrocytes is Reversed by the Phosphatase Inhibitor LB-100Poster2018 meeting of the American Society for Bone and Mineral Research2018Montreal, CAN.
Prevention of guanylyl cyclase-B dephosphorylation increases the length and cortical content of long bones.Poster8th Int'l Conf. on cGMP. cGMP: Generators, Effectors, Therap. Implications2017Bamberg, Germany
Hormonal control of meiosis by cyclic GMP: Live imaging of cGMP in mouse ovarian follicles.TalkFlorida Institute of Technology2016Melbourne, Florida
Changes in the phosphorylation of guanylyl cyclase-B (GC-B) regulates bone growth in a mouse model.PosterASBMR (American Society for Bone and Mineral Research) Annual Meeting2016Atlanta, Georgia
Phosphorylation of the cGMP phosphodiesterase PDE5 is required for the LH-induced increase in cGMP hydrolytic activity in mouse ovarian follicles.Poster49th Annual Meeting: Society for the Study of Reproduction2016San Diego, California
Luteinizing hormone signaling via cyclic GMP diffusion through gap junctionsTalkOocyte maturation and fertilization meeting IV2015Asamushi, Japan
Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase regulates oocyte meiotic resumption (Abstract published in BMC Pharmacology and Toxicology)Poster7th Int. Conf. - cGMP. cGMP:Generators,Effectors,Therap.Implications2015Trier, Germany
Luteinizing hormone signaling rapidly reduces cyclic GMP levels in rat ovarian follicles by dephosphorylation of NPR2 and phosphorylation of PDE5A, leading to meiotic resumption.PosterSociety for the Study of Reproduction Annual Meeting2015San Juan, Puerto Rico
Hormonal control of meiosis by cyclic GMP: Live imaging of cGMP in mouse ovarian folliclesTalkMRC Laboratory of Molecular Biology2015Cambridge, United Kingdom
Luteinizing hormone restarts meiosis through dephosphorylation and inactivation of the NPR2 guanylyl cyclase in the surrounding granulosa cellsPosterNortheast Regional Meeting of the Society for Developmental Biology2014Woods Hole, Massachusetts
Cyclic GMP-mediated intercellular communication in mammalian ovarian follicles. Presented at 6th International Conference on cGMP: Generators, Effectors and Therapeutic Implications (Abstract published in BMC Pharmacology and Toxicology)Poster6th Int. Conf. on cGMP: Generators, Effectors and Therapeutic Implications2013Erfurt, Germany
Luteinizing hormone signaling decreases cyclic GMP production in rat ovarian follicles by rapidly dephosphorylating the NPR2 guanylyl cyclase and by slowly decreasing its agonist CNPPosterEMBO Oocyte mat. and fert.: Lessons from canonical+emerging models2013Banyuls-sur-Mer, France
Spatial and temporal dynamics of the LH-induced decrease in cGMP in mouse ovarian follicles. Presented at thePosterEMBO Wks. Oocyte mat. and fert.: Lessons from canonical and emerging models2013Banyuls-sur-Mer, France
Luteinizing hormone reduces guanylyl cyclase activity in the granulosa cells of the mouse ovary, leading to the resumption of meiosis in the oocytePosterASCB Annual Meeting2011Denver, Colorado