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The molecular dissection of TRIM25's RNA-binding mechanism provides key insights into its antiviral activity.
Álvarez, Lucía; Haubrich, Kevin; Iselin, Louisa; Gillioz, Laurent; Ruscica, Vincenzo; Lapouge, Karine; Augsten, Sandra; Huppertz, Ina; Choudhury, Nila Roy; Simon, Bernd; Masiewicz, Pawel; Lethier, Mathilde; Cusack, Stephen; Rittinger, Katrin; Gabel, Frank; Leitner, Alexander; Michlewski, Gracjan; Hentze, Matthias W; Allain, Frédéric H T; Castello, Alfredo; Hennig, Janosch Nature communications 2024 Oct;15(1):8485
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Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport.
Heber, Simone; McClintock, Mark A; Simon, Bernd; Mehtab, Eve; Lapouge, Karine; Hennig, Janosch; Bullock, Simon L; Ephrussi, Anne Nature structural & molecular biology 2024 Jan;
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Structural basis of aggregate binding by the AAA+ disaggregase ClpG.
Katikaridis, Panagiotis; Simon, Bernd; Jenne, Timo; Moon, Seongjoon; Lee, Changhan; Hennig, Janosch; Mogk, Axel The Journal of biological chemistry 2023 Nov;299(11):105336
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Structural basis for specific RNA recognition by the alternative splicing factor RBM5.
Soni, Komal; Jagtap, Pravin Kumar Ankush; Martínez-Lumbreras, Santiago; Bonnal, Sophie; Geerlof, Arie; Stehle, Ralf; Simon, Bernd; Valcárcel, Juan; Sattler, Michael Nature communications 2023 Jul;14(1):4233
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Upstream of N-Ras C-terminal cold shock domains mediate poly(A) specificity in a novel RNA recognition mode and bind poly(A) binding protein.
Hollmann, Nele Merret; Jagtap, Pravin Kumar Ankush; Linse, Johanna-Barbara; Ullmann, Philip; Payr, Marco; Murciano, Brice; Simon, Bernd; Hub, Jochen S; Hennig, Janosch Nucleic acids research 2023 Feb;51(4):1895-1913
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Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex.
Soni, Komal; Sivadas, Anusree; Horvath, Attila; Dobrev, Nikolay; Hayashi, Rippei; Kiss, Leo; Simon, Bernd; Wild, Klemens; Sinning, Irmgard; Fischer, Tamás Nature communications 2023 Feb;14(1):772
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Structure and dynamics of the von Willebrand Factor C6 domain.
Chen, Po-Chia; Kutzki, Fabian; Mojzisch, Angelika; Simon, Bernd; Xu, Emma-Ruoqi; Aponte-Santamaría, Camilo; Horny, Kai; Jeffries, Cy; Schneppenheim, Reinhard; Wilmanns, Matthias; Brehm, Maria A; Gräter, Frauke; Hennig, Janosch Journal of structural biology 2022 Dec;214(4):107923
