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A model of actin-driven endocytosis explains differences of endocytic motility in budding and fission yeast.
Nickaeen, Masoud; Berro, Julien; Pollard, Thomas D; Slepchenko, Boris M Molecular Biology of the Cell 2022 Mar;mbcE21070362
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Actin assembly produces sufficient forces for endocytosis in yeast.
Nickaeen, Masoud; Berro, Julien; Pollard, Thomas D; Slepchenko, Boris M Molecular biology of the cell 2019 Jul;30(16):2014-2024
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A free-boundary model of a motile cell explains turning behavior.
Nickaeen, Masoud; Novak, Igor L; Pulford, Stephanie; Rumack, Aaron; Brandon, Jamie; Slepchenko, Boris M; Mogilner, Alex PLoS computational biology 2017 Nov;13(11):e1005862
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Numerical Approach to Spatial Deterministic-Stochastic Models Arising in Cell Biology.
Schaff, James C; Gao, Fei; Li, Ye; Novak, Igor L; Slepchenko, Boris M PLoS computational biology 2016 Dec;12(12):e1005236
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A conservative algorithm for parabolic problems in domains with moving boundaries.
Novak, Igor L; Slepchenko, Boris M Journal of computational physics 2014 Aug;270203-213
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Spatial modeling of cell signaling networks.
Cowan, Ann E; Moraru, Ion I; Schaff, James C; Slepchenko, Boris M; Loew, Leslie M Methods in cell biology 2012 Jan;110195-221
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Virtual Cell: computational tools for modeling in cell biology.
Resasco, Diana C; Gao, Fei; Morgan, Frank; Novak, Igor L; Schaff, James C; Slepchenko, Boris M Wiley interdisciplinary reviews. Systems biology and medicine 2012 Jan;4(2):129-40
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Diffusion amid random overlapping obstacles: similarities, invariants, approximations.
Novak, Igor L; Gao, Fei; Kraikivski, Pavel; Slepchenko, Boris M The Journal of chemical physics 2011 Apr;134(15):154104
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CLIP-170-dependent capture of membrane organelles by microtubules initiates minus-end directed transport.
Lomakin, Alexis J; Semenova, Irina; Zaliapin, Ilya; Kraikivski, Pavel; Nadezhdina, Elena; Slepchenko, Boris M; Akhmanova, Anna; Rodionov, Vladimir Developmental cell 2009 Sep;17(3):323-33
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Diffusion in cytoplasm: effects of excluded volume due to internal membranes and cytoskeletal structures.
Novak, Igor L; Kraikivski, Pavel; Slepchenko, Boris M Biophysical journal 2009 Aug;97(3):758-67
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Using the virtual cell simulation environment for extracting quantitative parameters from live cell fluorescence imaging data
Cowan A.E., Ye L., Morgan F.R., Koppel D.E., Slepchenko B.M., Loew L.M., Schaff J. Microscopy and Microanalysis 2009 Jan;15(SUPPL. 2):1522-1523
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Actin dynamics is essential for myosin-based transport of membrane organelles.
Semenova, Irina; Burakov, Anton; Berardone, Neda; Zaliapin, Ilya; Slepchenko, Boris; Svitkina, Tatyana; Kashina, Anna; Rodionov, Vladimir Current biology : CB 2008 Oct;18(20):1581-6
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Virtual Cell modelling and simulation software environment.
Moraru, I I; Schaff, J C; Slepchenko, B M; Blinov, M L; Morgan, F; Lakshminarayana, A; Gao, F; Li, Y; Loew, L M IET systems biology 2008 Sep;2(5):352-62
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Quantitative analysis of G-actin transport in motile cells.
Novak, Igor L; Slepchenko, Boris M; Mogilner, Alex Biophysical journal 2008 Aug;95(4):1627-38
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A model of the kinetics of lanthanum in human bone, using data collected during the clinical development of the phosphate binder lanthanum carbonate.
Bronner, Felix; Slepchenko, Boris M; Pennick, Michael; Damment, Stephen J P Clinical pharmacokinetics 2008 Jan;47(8):543-52
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Actin bundling: Initiation mechanisms and kinetics
Kraikivski, P., Slepchenko, B.M., Novak, I.L. Physical Review Letters 2008 Jan;101(12):
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On sensitivity amplification in intracellular signaling cascades.
Rácz, Eva; Slepchenko, Boris M Physical biology 2008 Jan;5(3):036004
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Switching of membrane organelles between cytoskeletal transport systems is determined by regulation of the microtubule-based transport.
Slepchenko, Boris M; Semenova, Irina; Zaliapin, Ilya; Rodionov, Vladimir The Journal of cell biology 2007 Nov;179(4):635-41
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Diffusion on a Curved Surface Coupled to Diffusion in the Volume: Application to Cell Biology.
Novak, Igor L; Gao, Fei; Choi, Yung-Sze; Resasco, Diana; Schaff, James C; Slepchenko, Boris M Journal of computational physics 2007 Oct;226(2):1271-1290
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In vivo dynamics of Rac-membrane interactions.
Moissoglu, Konstadinos; Slepchenko, Boris M; Meller, Nahum; Horwitz, Alan F; Schwartz, Martin A Molecular biology of the cell 2006 Jun;17(6):2770-9
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Modeling and analysis of calcium signaling events leading to long-term depression in cerebellar Purkinje cells.
Hernjak, Nicholas; Slepchenko, Boris M; Fernald, Kathleen; Fink, Charles C; Fortin, Dale; Moraru, Ion I; Watras, James; Loew, Leslie M Biophysical journal 2005 Dec;89(6):3790-806
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Cooperativity between cell contractility and adhesion.
Novak, Igor L; Slepchenko, Boris M; Mogilner, Alex; Loew, Leslie M Physical review letters 2004 Dec;93(26 Pt 1):268109
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Cyclin aggregation and robustness of bio-switching.
Slepchenko, Boris M; Terasaki, Mark Molecular biology of the cell 2003 Nov;14(11):4695-706
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Centrosome positioning in interphase cells.
Burakov, Anton; Nadezhdina, Elena; Slepchenko, Boris; Rodionov, Vladimir The Journal of cell biology 2003 Sep;162(6):963-9
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A new model for nuclear envelope breakdown.
Terasaki, M; Campagnola, P; Rolls, M M; Stein, P A; Ellenberg, J; Hinkle, B; Slepchenko, B Molecular biology of the cell 2001 Feb;12(2):503-10
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An image-based model of calcium waves in differentiated neuroblastoma cells.
Fink, C C; Slepchenko, B; Moraru, I I; Watras, J; Schaff, J C; Loew, L M Biophysical journal 2000 Jul;79(1):163-83
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Numerical Approach to Fast Reactions in Reaction-Diffusion Systems: Application to Buffered Calcium Waves in Bistable Models
Slepchenko B.M., Schaff J.C., Choi Y.S. Journal of Computational Physics 2000 Jan;162(1):186-218
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Morphological control of inositol-1,4,5-trisphosphate-dependent signals.
Fink, C C; Slepchenko, B; Moraru, I I; Schaff, J; Watras, J; Loew, L M The Journal of cell biology 1999 Nov;147(5):929-36
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Determination of time-dependent inositol-1,4,5-trisphosphate concentrations during calcium release in a smooth muscle cell.
Fink, C C; Slepchenko, B; Loew, L M Biophysical journal 1999 Jul;77(1):617-28
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Electrodiffusion of ions inside living cells
Choi Y.S., Resasco D., Schaff J., Slepchenko B. IMA Journal of Applied Mathematics (Institute of Mathematics and Its Applications) 1999 Jan;62(3):207-226
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A general computational framework for modeling cellular structure and function.
Schaff, J; Fink, C C; Slepchenko, B; Carson, J H; Loew, L M Biophysical journal 1997 Sep;73(3):1135-46
