David C. Steffens, MD, MHSSamuel “Sy” Birnbaum/Ida, Louis and Richard Blum Chair in PsychiatryProfessor and Chair, Department of Psychiatry
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- Overview
- Education & Training
- Clinical Interests
- Teaching
- Committees & Organizations
- Research
- Research Opportunities
- Lab Rotations
- Publications
- Presentations
Dr. Steffens became chair of UConn Psychiatry in July, 2012, after more than 20 years at Duke University School of Medicine, where he had served as a professor of psychiatry, vice chair for education and division chief of Geriatric Psychiatry in the Department of Psychiatry and Behavioral Sciences. Dr. Steffens is the past president of the American Association for Geriatric Psychiatry, has authored more than 350 peer-reviewed papers and is the lead editor of the leading textbook in geriatric psychiatry. Dr. Steffens also has considerable experience in medical education and mentoring undergraduate and graduate students, medical students, resident physicians, post-doctoral fellows and junior faculty. A graduate of Rice University and the University of Texas, Houston Health Science Center School of Medicine, Dr. Steffens moved to Duke in 1988, where he completed his internship and residency in psychiatry. Since joining the Duke faculty and now at UConn Health, Dr. Steffens' career has focused on mood and cognitive disorders in older adults.
Dr. Steffens received a Master’s of Health Science in Clinical Research from Duke in 2000. He has held an NIMH-supported Mid-Career Development Award, and his major area of research focuses on links between depression in later life and development of cognitive decline and dementia. Dr. Steffens has been continuously supported by NIMH/NIH for over twenty years. At UConn, Dr. Steffens has continued his research pursuits with a new NIMH-supported study, known as NBOLD, that examines the relationship between stress and depression in older adults. He is also the Principal Investigator of an NIMH-supported clinical trial of a computer-based cognitive intervention to treat late-life depression. In addition, Dr. Steffens' research and mentorship activity at UConn Health have been supported by a generous gift from the Leo and Anne Albert Trust. He also serves as Leader of the Research Education Component of the UConn Pepper Center.
With new faculty hires in psychiatry and neuropsychology, Dr. Steffens has developed a clinical geriatric mental health service that focuses on assessment and treatment of anxiety, depression and cognitive disorders in the elderly. Faculty also contribute to the research endeavors of the Mood, Cognition and Aging Research Program (MCAR).
Degree | Institution | Major |
---|---|---|
BA | Rice University | Biochemistry |
MD | University of Texas Health Science Center at Houston | Medicine |
MHSc | Duke University Medical Center | Health Sciences |
Post-Graduate Training
Training | Institution | Specialty |
---|---|---|
Residency | Duke University Medical Center | Psychiatry |
Awards
Name of Award/Honor | Awarding Organization |
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Distinguished Life Fellow | American Psychiatric Association |
Martin Symonds, M.D. "Man of Good Conscience" Award for Supporting and Advancing the Careers of Women Psychiatrists | Association of Women Psychiatrists |
Geriatric Psychiatry Research Award | American College of Psychiatrists |
Invited Lecturer, Lawrence G. Raisz Lectureship in Clinical and Translational Research | UConn Health Center |
Annual Clinically Based Research Mentoring Award | Duke University School of Medicine |
Gerald L. Klerman Young Investigator Award | Depression and Bipolar Support Alliance |
Junior Investigator Award | American Association for Geriatric Psychiatry |
Late life depression and cognitive disorders.
Dr. Steffens has lectured to medical students, MPH students, psychiatric residents and geriatric psychiatry and medicine fellows on late-life depression, dementia, and other topics related to mental health in older adults. In the new MDelta curriculum, Dr. Steffens works with other faculty to facilitate learning about dementia assessment and management.
Name & Description | Category | Role | Type | Scope | Start Year | End Year |
---|---|---|---|---|---|---|
ZMH1 ERB-Q (07) R Optimizing Digital Mental Health Interventions (R01) | Study Section | Chair | External | National | 2022 | 2022 |
Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50) | Study Section | Chair | National | 2021 | 2021 | |
Patterson Trust Review Committee | Study Section | Chair | External | Regional | 2021 | 2022 |
2021/01 ZMH1 ERB-N (01) P Advanced Laboratories for Accelerating the Reach and Impact Research Centers (P50) (Teleconference), November 9, 2020 | Study Section | Reviewer | External | National | 2020 | 2020 |
NIMH Meeting 2020/10 ZMH1-ERB-N-02 - 07/07/2020 | Study Section | Chair | External | National | 2020 | 2020 |
Faculty Consulting Director Search Committee | Other | Chair | UConn Health | Local | 2020 | 2020 |
Task Force on Predatory Journals and Conferences | Advisory Committee | Chair | UConn Health | Local | 2018 | 2019 |
Editorial Board, American Journal of Geriatric Psychiatry | Editorial Board | Associate Editor | External | National | 2017 | 2022 |
NIH Study Section, Caregiving for Alzheimer’s Disease SEP, ZRG1 HDM-Y (57) | Study Section | Chair | External | National | 2017 | 2018 |
Neuroscience Chair Search Committee | Other | Committee Member | UConn Health | University | 2016 | 2017 |
Research Council | Other | Member | UConn Health | University | 2015 | 2021 |
UConn Health AAUP Management Negotiating Team | Other | Member | UConn Health | University | 2014 | 2017 |
American Association for Geriatric Psychiatry | Professional/Scientific Organization | President | External | National | 2013 | 2014 |
Neuroscience Department Review Committee | Other | Member | UConn Health | University | 2013 | 2013 |
Senior Appointments and Promotions Committee (SAPC) | Other | Member | UConn Health | University | 2013 | 2022 |
Clinical Council | Other | Member | UConn Health | University | 2013 | 2016 |
Vice President for Human Resources Search Committee | Other | Member | UConn Health | University | 2012 | 2013 |
NIH Study Section, Adult Psychopathology and Disorders of Aging | Study Section | Chair | External | National | 2003 | 2005 |
NIH Study Section, ZRG1 BBBP-5 | Study Section | Chair | External | National | 2002 | 2003 |
Dr. Steffens has been funded by the NIH for over twenty-five years. His research focuses on links between late life depression and subsequent cognitive decline and development of dementia. Assessments include structural and functional brain imaging, neuropsychological testing, blood work for peripheral markers and genetics, personality assessment, functional status, and measures of stress and social support. He is also interested in cognitive interventions that improve mood.
Undergraduate, graduate and medical students and trainees interested in working with Dr. Steffens should contact him at steffens@uchc.edu.
Not accepting lab rotation students at this time.
Journal Articles
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Proteogenomic signature of risk of Alzheimer's disease and related dementia risk in individuals with a history of major depression disorder.
medRxiv : the preprint server for health sciences 2024 Sep;
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The Role of State Versus Trait Anxiety on Cognition in Older Adults With Major Depressive Disorder.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2024 Sep;32(9):1130-1140
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Hybrid representation learning for cognitive diagnosis in late-life depression over 5 years with structural MRI.
Medical image analysis 2024 Mar;94103135
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Computerized cognitive remediation of Long COVID in older adults.
International psychogeriatrics 2024 Feb;1-3
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Life-Course Brain Health as a Determinant of Late-Life Mental Health: American Association for Geriatric Psychiatry Expert Panel Recommendations.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2023 Sep;
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The Risk for Loneliness and Major Depression among Solo Agers.
Journal of applied gerontology : the official journal of the Southern Gerontological Society 2023 May;42(5):962-971
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Neuroimaging features of depression-frailty phenotype in older adults: a pilot study.
International psychogeriatrics 2023 Feb;1-7
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High Risk of Substance Use Disorder-Related Outcomes in Veterans Released from Correctional Facilities in Mid to Late Life.
Journal of general internal medicine 2023 Feb;
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Association of Race, Ethnicity, Education, and Neighborhood Context With Dementia Prevalence and Cognitive Impairment Severity Among Older Adults Receiving Medicaid-Funded Home and Community-Based Services.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2022 Dec;
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Different loneliness types, cognitive function, and brain structure in midlife: Findings from the Framingham Heart Study.
EClinicalMedicine 2022 Nov;53101643
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Reliable Cognitive Decline in Late-Life Major Depression.
Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists 2022 Oct;
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Effects of Longitudinal Changes in Neuroticism and Stress on Cognitive Decline.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2022 Oct;
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Comparison of Long-Term Efficacy and Safety of Esketamine Nasal Spray Plus Oral Antidepressant in Younger Versus Older Patients With Treatment-Resistant Depression: Post-Hoc Analysis of SUSTAIN-2, a Long-Term Open-Label Phase 3 Safety and Efficacy Study.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2022 May;30(5):541-556
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Association of 1-year change in neuroticism and 3-year change in cognitive performance among older depressed adults.
International psychogeriatrics 2022 Mar;1-6
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Structural brain changes and neuroticism in late-life depression: a neural basis for depression subtypes.
International psychogeriatrics 2021 Mar;1-6
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Associations of loneliness with risk of Alzheimer's disease dementia in the Framingham Heart Study.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2021 Mar;
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Effects of physical exercise on the aging brain across imaging modalities: A meta-analysis of neuroimaging studies in randomized controlled trials.
International journal of geriatric psychiatry 2021 Feb;
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Depression and Dementia Risk: Research Findings That Are Shovel-Ready for Clinicians.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2021 Jan;
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Hemochromatosis Mutations, Brain Iron Imaging, and Dementia in the UK Biobank Cohort.
Journal of Alzheimer's disease : JAD 2021 Jan;79(3):1203-1211
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Pharmacist Identification of Medication Therapy Problems Involving Cognition Among Older Adults Followed by a Home-Based Care Team.
Drugs & aging 2020 Dec;
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Cognitive variability, brain aging, and cognitive decline in late-life major depression.
International journal of geriatric psychiatry 2020 Nov;
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Blue Genes, Exercise, and Cognition in Late-Life Depression: A Lot of Moving Parts.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2020 Sep;28(9):968-970
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Genome-wide screen to identify genetic loci associated with cognitive decline in late-life depression.
International psychogeriatrics 2020 Jul;1-9
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Ethical and Logistical Considerations of Caring for Older Adults on Inpatient Psychiatry During the COVID-19 Pandemic.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2020 May;
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The Interaction of Personality and Social Support on Prospective Suicidal Ideation in Men and Women With Late-Life Depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2020 Apr;
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COVID-19, Mental Health and Aging: A Need for New Knowledge to Bridge Science and Service.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2020 Mar;
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Clinical trial testing in-home multidisciplinary care management for older adults with cognitive vulnerability: Rationale and study design.
Contemporary clinical trials 2020 Mar;92105992
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Functional disability, depression, and suicidal ideation in older prisoners.
Journal of Affective Disorders, 2020 2020 Jan;266366-373
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Is it time to do away with disorders in the very old?
International psychogeriatrics 2019 Nov;31(11):1535-1537
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Dynamic changes in thalamic connectivity following stress and its association with future depression severity.
Brain and behavior 2019 Oct;e01445
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Efficacy and Safety of Esketamine Nasal Spray Plus an Oral Antidepressant in Elderly Patients With Treatment-Resistant Depression-TRANSFORM-3.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2019 Oct;
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Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults.
Journal of the American Geriatrics Society 2019 May;
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Vascular Depression: Is an Old Research Construct Finally Ready for Clinical Prime Time?
Biological psychiatry 2019 Mar;85(6):441-442
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Training the Next Generation of Geriatric-Focused Clinical Neuroscientists.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2019 Mar;
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Increased ventromedial prefrontal cortex activity and connectivity predict poor sertraline treatment outcome in late-life depression.
International journal of geriatric psychiatry 2019 Feb;
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Functional connectivity predictors of acute depression treatment outcome.
International psychogeriatrics 2019 Jan;1-5
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Recent advances in the use of imaging in psychiatry: functional magnetic resonance imaging of large-scale brain networks in late-life depression.
F1000Research 2019 Jan;8
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Perspectives on the Management of Vascular Depression.
The American journal of psychiatry 2018 Dec;175(12):1169-1175
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Increased Risk of Suicide Attempts and Unintended Death Among Those Transitioning From Prison to Community in Later Life.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2018 Nov;26(11):1165-1174
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Physical exercise increases involvement of motor networks as a compensatory mechanism during a cognitively challenging task.
International journal of geriatric psychiatry 2018 May;331153-1159
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Increased plasma complement factor H is associated with geriatric depression.
International psychogeriatrics 2018 May;1-8
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Predictors of recurrence in remitted late-life depression.
Depression and anxiety 2018 May;35658-667
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State of the Science of Neural Systems in Late-Life Depression: Impact on Clinical Presentation and Treatment Outcome.
Journal of the American Geriatrics Society 2018 Apr;66 Suppl 1S17-S23
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A Geriatrics Perspective on Dementia Prevention and Treatment.
The American journal of psychiatry 2018 Mar;175(3):199-201
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A New Measure for Neural Compensation Is Positively Correlated With Working Memory and Gait Speed.
Frontiers in aging neuroscience 2018 Jan;1071
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Putamen Volume Differences Among Older Adults: Depression Status, Melancholia, and Age.
Journal of geriatric psychiatry and neurology 2018 Jan;31(1):39-49
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Presence of neuroticism and antidepressant remission rates in late-life depression: results from the Neurobiology of Late-Life Depression (NBOLD) study.
International psychogeriatrics 2017 Dec;301069-1074
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Longitudinal Cognitive Outcomes of Clinical Phenotypes of Late-Life Depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2017 Oct;25(10):1123-1134
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Negative Affectivity, Aging, and Depression: Results From the Neurobiology of Late-Life Depression (NBOLD) Study.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2017 Oct;25(10):1135-1149
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Length of axons expressing the serotonin transporter in orbitofrontal cortex is lower with age in depression.
Neuroscience 2017 Jul;35930-39
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Late-Life Depression and the Prodromes of Dementia.
JAMA psychiatry 2017 May;74673-674
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Neuroticism Traits Selectively Impact Long Term Illness Course and Cognitive Decline in Late-Life Depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2017 Mar;25(3):220-229
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Cortical brain volume abnormalities associated with few or multiple neuropsychiatric symptoms in Alzheimer's disease.
PloS one 2017 Jan;12(5):e0177169
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Multiple Neuroimaging Measures for Examining Exercise-induced Neuroplasticity in Older Adults: A Quasi-experimental Study.
Frontiers in aging neuroscience 2017 Jan;9102
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Effects of stressful life events on cerebral white matter hyperintensity progression.
International journal of geriatric psychiatry 2016 Dec;32e10-e17
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Appetite and Weight Loss Symptoms in Late-Life Depression Predict Dementia Outcomes.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2016 Oct;24(10):870-8
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Getting on Message: Preventing Alzheimer Disease Through Diet and Exercise.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2016 Sep;24(9):738-9
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J'accuse! depression as a likely culprit in cases of AD.
International psychogeriatrics / IPA 2016 Sep;28(9):1407-8
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Decreased between-hemisphere connectivity strength and network efficiency in geriatric depression.
Human brain mapping 2016 Aug;3853-67
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The treatment of behavioral and psychological symptoms of dementia: weighing benefits and risks.
Current Alzheimer research 2016 May;131124-33
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Characteristics of neurocognitive functions in mild cognitive impairment with depression.
International psychogeriatrics / IPA 2016 Mar;281181-90
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A Call to Restructure Psychiatry General and Subspecialty Training.
Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2016 Feb;40(1):145-8
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Late-life Depression Modifies the Association Between Cerebral White Matter Hyperintensities and Functional Decline Among Older Adults.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2016 Jan;24(1):42-9
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Heterogeneity in the three-year course of major depression among older adults.
International journal of geriatric psychiatry 2015 Nov;31775-82
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Cognitive functioning throughout the treatment history of clinical late-life depression.
International journal of geriatric psychiatry 2015 Oct;30(10):1076-84
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Methodology and preliminary results from the neurobiology of late-life depression study.
International psychogeriatrics / IPA 2015 Sep;27(12):1987-97
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Physical frailty in late-life depression is associated with deficits in speed-dependent executive functions.
International journal of geriatric psychiatry 2015 Aug;31466-74
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Amyloid-associated depression and ApoE4 allele: longitudinal follow-up for the development of Alzheimer's disease.
International journal of geriatric psychiatry 2015 Aug;31316-22
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Inflammation Markers and Major Depressive Disorder in Patients With Chronic Heart Failure: Results From the Sertraline Against Depression and Heart Disease in Chronic Heart Failure Study.
Psychosomatic medicine 2015 Jul;77(7):808-15
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Anxiety symptoms in amnestic mild cognitive impairment are associated with medial temporal atrophy and predict conversion to Alzheimer disease.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2015 May;23(5):466-76
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Disability but not social support predicts cognitive deterioration in late-life depression.
International psychogeriatrics / IPA 2014 Dec;27(5):707-14
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Hippocampus atrophy and the longitudinal course of late-life depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2014 Dec;22(12):1504-12
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Factors associated with cognitive evaluations in the United States.
Neurology 2014 Nov;84(1):64-71
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Agitation in cognitive disorders: International Psychogeriatric Association provisional consensus clinical and research definition.
International psychogeriatrics / IPA 2014 Oct;27(1):7-17
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Relative effectiveness of reappraisal and distraction in regulating emotion in late-life depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2014 Sep;22(9):898-907
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Amnestic mild cognitive impairment and incident dementia and Alzheimer's disease in geriatric depression.
International psychogeriatrics / IPA 2014 Jul;26(12):2029-36
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Cingulum bundle white matter lesions influence antidepressant response in late-life depression: a pilot study.
Journal of affective disorders 2014 Jun;1628-11
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Vascular lesions and functional limitations among older adults: does depression make a difference?
International psychogeriatrics / IPA 2014 May;1-9
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Elevated brain lesion volumes in older adults who use calcium supplements: a cross-sectional clinical observational study.
The British journal of nutrition 2014 Apr;112(2):220-7
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Angiotensin converting enzyme inhibitors and Alzheimer disease in the presence of the apolipoprotein E4 allele.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2014 Feb;22(2):177-85
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Clinical outcomes of older depressed patients with and without comorbid neuroticism.
International psychogeriatrics / IPA 2013 Dec;25(12):1985-90
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What are the causes of late-life depression?
The Psychiatric clinics of North America 2013 Dec;36(4):497-516
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Exercise for late-life depression? It depends.
Lancet (London, England) 2013 Jul;382(9886):4-5
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In our hands: responding to the IOM report on workforce needs for older adults with mental health and substance use disorders.
International psychogeriatrics / IPA 2013 Jul;25(7):1039-40
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Late-life onset bipolar disorder presenting as a case of pseudo-dementia: a case discussion and review of literature.
The Yale journal of biology and medicine 2013 Jun;86(2):235-44
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Negative life stress and longitudinal hippocampal volume changes in older adults with and without depression.
Journal of psychiatric research 2013 Jun;47(6):829-34
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Serum ionized calcium may be related to white matter lesion volumes in older adults: a pilot study.
Nutrients 2013 Jun;5(6):2192-205
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Fiber tract-specific white matter lesion severity Findings in late-life depression and by AGTR1 A1166C genotype.
Human brain mapping 2013 Feb;34(2):295-303
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Association of attentional shift and reversal learning to functional deficits in geriatric depression.
International journal of geriatric psychiatry 2012 Nov;27(11):1172-9
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Latent class-derived subgroups of depressive symptoms in a community sample of older adults: the Cache County Study.
International journal of geriatric psychiatry 2012 Oct;27(10):1061-9
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Clinical and sociodemographic factors in a sample of older subjects experiencing depressive symptoms.
International journal of geriatric psychiatry 2012 Sep;27(9):924-30
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Neural correlates associated with cognitive decline in late-life depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2012 Aug;20(8):653-63
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Depressed older patients with the atypical features of interpersonal rejection sensitivity and reversed-vegetative symptoms are similar to younger atypical patients.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2012 Jul;20(7):622-34
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Stressful life events, perceived stress, and 12-month course of geriatric depression: direct effects and moderation by the 5-HTTLPR and COMT Val158Met polymorphisms.
Stress (Amsterdam, Netherlands) 2012 Jul;15(4):425-34
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Depressive symptoms and mild cognitive impairment in the elderly: an ominous combination.
Biological psychiatry 2012 May;71(9):762-4
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Impact of BDNF Val66Met and 5-HTTLPR polymorphism variants on neural substrates related to sadness and executive function.
Genes, brain, and behavior 2012 Apr;11(3):352-9
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Neuropsychological Predictors of Dementia in Late-Life Major Depressive Disorder.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2012 Mar;
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Plasma omega-3 polyunsaturated fatty acids and survival in patients with chronic heart failure and major depressive disorder.
Journal of cardiovascular translational research 2012 Feb;5(1):92-9
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Religion and the presence and severity of depression in older adults.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2012 Feb;20(2):188-92
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Association of five-factor model personality domains and facets with presence, onset, and treatment outcomes of major depression in older adults.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2012 Jan;21(1):88-96
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Depression, hippocampal volume changes, and cognitive decline in a clinical sample of older depressed outpatients and non-depressed controls.
Aging & mental health 2012 Jan;16(6):753-62
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Longitudinal relationships of religion with posttreatment depression severity in older psychiatric patients: evidence of direct and indirect effects.
Depression research and treatment 2012 Jan;2012745970
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A functional alternative splicing mutation in human tryptophan hydroxylase-2.
Molecular psychiatry 2011 Dec;16(12):1169-76
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Change in stress and social support as predictors of cognitive decline in older adults with and without depression.
International journal of geriatric psychiatry 2011 Dec;26(12):1267-74
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Comorbid cognitive impairment and functional trajectories in low vision rehabilitation for macular disease.
Aging clinical and experimental research 2011 Nov;23(5-6):343-50
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MRI-defined vascular depression: a review of the construct.
International journal of geriatric psychiatry 2011 Nov;26(11):1101-8
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Amygdala volume in late-life depression: relationship with age of onset.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2011 Sep;19(9):771-6
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Early parental death and remarriage of widowed parents as risk factors for Alzheimer disease: the Cache County study.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2011 Sep;19(9):814-24
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Incidence of dementia and cognitive impairment, not dementia in the United States.
Annals of neurology 2011 Sep;70(3):418-26
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Heterogeneity in symptom profiles among older adults diagnosed with major depression.
International psychogeriatrics / IPA 2011 Aug;23(6):906-22
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Reduction of dorsolateral prefrontal cortex gray matter in late-life depression.
Psychiatry research 2011 Jul;193(1):1-6
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Efficacy and safety of adjunctive aripiprazole in major depressive disorder in older patients: a pooled subpopulation analysis.
International journal of geriatric psychiatry 2011 Jun;26(6):564-72
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Structural neuroimaging of geriatric depression.
The Psychiatric clinics of North America 2011 Jun;34(2):423-35, ix
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BDNF Val66Met genotype and 6-month remission rates in late-life depression.
The pharmacogenomics journal 2011 Apr;11(2):146-54
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Neuropsychiatric symptoms and the risk of institutionalization and death: the aging, demographics, and memory study.
Journal of the American Geriatrics Society 2011 Mar;59(3):473-81
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Social support modifies the relationship between personality and depressive symptoms in older adults.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2011 Feb;19(2):123-31
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Altered cerebellar-cerebral functional connectivity in geriatric depression.
PloS one 2011 Jan;6(5):e20035
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Associations of religious behavior and experiences with extent of regional atrophy in the orbitofrontal cortex during older adulthood.
Religion, brain & behavior 2011 Jan;1(2):103-118
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BDNF Val66Met genotype and six-month remission rates in late-life depression.
Pharmacogenomics J. 2011 Jan;11(2):146-54
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Change in hippocampal volume on magnetic resonance imaging and cognitive decline among older depressed and nondepressed subjects in the neurocognitive outcomes of depression in the elderly study.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2011 Jan;19(1):4-12
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Cross-cultural considerations in administering the center for epidemiologic studies depression scale.
Gerontology 2011 Jan;57(5):455-61
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Religious factors and hippocampal atrophy in late life.
PloS one 2011 Jan;6(3):e17006
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Structural integrity of the uncinate fasciculus and resting state functional connectivity of the ventral prefrontal cortex in late life depression.
PloS one 2011 Jan;6(7):e22697
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The moderating effect of the APOE [small element of] 4 allele on the relationship between hippocampal volume and cognitive decline in older depressed patients.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2011 Jan;19(1):23-32
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Quetiapine XR: current status for the treatment of major depressive disorder.
Progress in neuro-psychopharmacology & biological psychiatry 2010 Oct;34(7):1165-73
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Cerebrovascular risk factors and cerebral hyperintensities among middle-aged and older adults with major depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2010 Sep;18(9):848-52
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Differential patterns of cognitive decline in anterior and posterior white matter hyperintensity progression.
Stroke; a journal of cerebral circulation 2010 Sep;41(9):1946-50
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Functional evidence implicating a novel TOR1A mutation in idiopathic, late-onset focal dystonia.
Journal of medical genetics 2010 Sep;47(9):646-50
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Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects.
Biochimica et biophysica acta 2010 Aug;1801(8):951-9
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Angiotensin receptor gene polymorphisms and 2-year change in hyperintense lesion volume in men.
Molecular psychiatry 2010 Aug;15(8):816-22
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Depressive morbidity and gender in community-dwelling Brazilian elderly: systematic review and meta-analysis.
International psychogeriatrics / IPA 2010 Aug;22(5):712-26
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Metabolomic differences in heart failure patients with and without major depression.
Journal of geriatric psychiatry and neurology 2010 Jun;23(2):138-46
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White matter hyperintensities and their association with suicidality in major affective disorders: a meta-analysis of magnetic resonance imaging studies.
CNS spectrums 2010 Jun;15(6):375-81
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Greater risk of dementia when spouse has dementia? The Cache County study.
Journal of the American Geriatrics Society 2010 May;58(5):895-900
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Cholinesterase inhibitors as adjunctive therapy in patients with schizophrenia and schizoaffective disorder: a review and meta-analysis of the literature.
CNS drugs 2010 Apr;24(4):303-17
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The brain-derived neurotrophic factor Val66Met polymorphism, hippocampal volume, and cognitive function in geriatric depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2010 Apr;18(4):323-31
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Support for the vascular depression hypothesis in late-life depression: results of a 2-site, prospective, antidepressant treatment trial.
Archives of general psychiatry 2010 Mar;67(3):277-85
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Prevalence of neuropsychiatric symptoms and their association with functional limitations in older adults in the United States: the aging, demographics, and memory study.
Journal of the American Geriatrics Society 2010 Feb;58(2):330-7
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Imaging and genetics advances in understanding geriatric depression.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010 Jan;35(1):349-50
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Trajectories of mobility and IADL function in older patients diagnosed with major depression.
International journal of geriatric psychiatry 2010 Jan;25(1):74-81
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Variability in frontotemporal brain structure: the importance of recruitment of African Americans in neuroscience research.
PloS one 2010 Jan;5(10):e13642
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A multiplicity of approaches to characterize geriatric depression and its outcomes.
Current opinion in psychiatry 2009 Nov;22(6):522-6
-
Cognitive performance and informant reports in the diagnosis of cognitive impairment and dementia in African Americans and whites.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2009 Nov;5(6):445-53
-
Influence of the MTHFR C677T polymorphism on magnetic resonance imaging hyperintensity volume and cognition in geriatric depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2009 Oct;17(10):847-55
-
Natural food folate and late-life depression.
Journal of nutrition for the elderly 2009 Oct;28(4):348-58
-
Prevalence of depression among older Americans: the Aging, Demographics and Memory Study.
International psychogeriatrics / IPA 2009 Oct;21(5):879-88
-
The COMT Val158Met polymorphism and cognition in depressed and nondepressed older adults.
International journal of geriatric psychiatry 2009 Oct;24(10):1127-33
-
The moderating role of personality factors in the relationship between depression and neuropsychological functioning among older adults.
International journal of geriatric psychiatry 2009 Sep;24(9):1010-9
-
Association analysis of the COMT/MTHFR genes and geriatric depression: an MRI study of the putamen.
International journal of geriatric psychiatry 2009 Aug;24(8):847-55
-
Reductions in neuronal density in elderly depressed are region specific.
International journal of geriatric psychiatry 2009 Aug;24(8):856-64
-
Clinically significant depressive symptoms and associated factors in community elderly subjects from Sao Paulo, Brazil.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2009 Jul;17(7):582-90
-
Thyroid hormones affect recovery from depression during antidepressant treatment.
Psychiatry and clinical neurosciences 2009 Jun;63(3):305-13
-
Prevalence and patterns of comorbid cognitive impairment in low vision rehabilitation for macular disease.
Archives of gerontology and geriatrics 2009 May;50(2):209-12
-
Profiles of depressive symptoms in older adults diagnosed with major depression: latent cluster analysis.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2009 May;17(5):387-96
-
Twin pairs discordant for neuropathologically confirmed Lewy body dementia.
Journal of neurology, neurosurgery, and psychiatry 2009 May;80(5):562-5
-
Biochemical abnormalities of the medial temporal lobe and medial prefrontal cortex in late-life depression.
Psychiatry research 2009 Apr;172(1):49-54
-
Effectiveness of antidepressant treatments in pre-menopausal versus post-menopausal women: a pilot study on differential effects of sex hormones on antidepressant effects.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2009 Mar;63(3):228-35
-
Neuropsychological correlates of magnetic resonance imaging-defined subcortical ischemic depression.
International journal of geriatric psychiatry 2009 Mar;24(3):219-25
-
Outcomes of older cognitively impaired individuals with current and past depression in the NCODE study.
Journal of geriatric psychiatry and neurology 2009 Mar;22(1):52-61
-
APOE related hippocampal shape alteration in geriatric depression.
NeuroImage 2009 Feb;44(3):620-6
-
Course of suicide ideation and predictors of change in depressed older adults.
Journal of affective disorders 2009 Feb;113(1-2):30-6
-
Glycemic index and glycemic load are not associated with brain lesions in the elderly.
The journal of nutrition, health & aging 2009 Feb;13(2):117-20
-
Multiple rare SAPAP3 missense variants in trichotillomania and OCD.
Molecular psychiatry 2009 Jan;14(1):6-9
-
Does neurotropin-3 have a therapeutic implication in major depression?
The International journal of neuroscience 2008 Nov;118(11):1515-22
-
Social support in older individuals: the role of the BDNF Val66Met polymorphism.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008 Oct;147B(7):1205-12
-
The vascular depression subtype: evidence of internal validity.
Biological psychiatry 2008 Sep;64(6):491-7
-
Midlife activity predicts risk of dementia in older male twin pairs.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2008 Sep;4(5):324-31
-
Neurocognitive correlates of response to treatment in late-life depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2008 Sep;16(9):752-9
-
Cerebrospinal fluid dehydroepiandrosterone levels are correlated with brain dehydroepiandrosterone levels, elevated in Alzheimer's disease, and related to neuropathological disease stage.
The Journal of clinical endocrinology and metabolism 2008 Aug;93(8):3173-8
-
Do estradiol levels influence on the cognitive function during antidepressant treatments in post-menopausal women with major depressive disorder? A comparison with pre-menopausal women.
Neuro endocrinology letters 2008 Aug;29(4):500-6
-
Separating mood disturbance from mild cognitive impairment in geriatric depression.
International review of psychiatry (Abingdon, England) 2008 Aug;20(4):374-81
-
Hippocampal volumes and depression subtypes.
Psychiatry research 2008 Jul;163(2):126-32
-
Depressive state- and disease-related alterations in neural responses to affective and executive challenges in geriatric depression.
The American journal of psychiatry 2008 Jul;165(7):863-71
-
Age-dependent reduction of amygdala volume in bipolar disorder.
Psychiatry research 2008 May;163(1):84-94
-
Amyloid-associated depression: a prodromal depression of Alzheimer disease?
Archives of general psychiatry 2008 May;65(5):542-50
-
Calcium and vitamin D intakes may be positively associated with brain lesions in depressed and nondepressed elders.
Nutrition research (New York, N.Y.) 2008 May;28(5):285-92
-
Church attendance and new episodes of major depression in a community study of older adults: the Cache County Study.
The journals of gerontology. Series B, Psychological sciences and social sciences 2008 May;63(3):P129-37
-
The brain-derived neurotrophic factor VAL66MET polymorphism and cerebral white matter hyperintensities in late-life depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2008 Apr;16(4):263-71
-
The course of depressive symptoms in older adults with comorbid major depression and dysthymia.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2008 Apr;16(4):300-9
-
Prevalence of cognitive impairment without dementia in the United States.
Annals of internal medicine 2008 Mar;148(6):427-34
-
Antidepressant treatment and worsening white matter on serial cranial magnetic resonance imaging in the elderly: the Cardiovascular Health Study.
Stroke; a journal of cerebral circulation 2008 Mar;39(3):857-62
-
Short/long heterozygotes at 5HTTLPR and white matter lesions in geriatric depression.
International journal of geriatric psychiatry 2008 Mar;23(3):244-8
-
Is there protective haplotype of dysbindin gene (DTNBP1) 3 polymorphisms for major depressive disorder.
Progress in neuro-psychopharmacology & biological psychiatry 2008 Feb;32(2):375-9
-
Aging, gender, and the elderly adult brain: an examination of analytical strategies.
Neurobiology of aging 2008 Feb;29(2):290-302
-
Geriatric depression and cognitive impairment.
Psychological medicine 2008 Feb;38(2):163-75
-
Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the Cache County Study.
International journal of geriatric psychiatry 2008 Feb;23(2):170-7
-
The effects of antidepressant medication adherence as well as psychosocial and clinical factors on depression outcome among older adults.
International journal of geriatric psychiatry 2008 Feb;23(2):129-34
-
Hippocampus shape analysis and late-life depression.
PloS one 2008 Jan;3(3):e1837
-
Five-year trajectories of social networks and social support in older adults with major depression.
International psychogeriatrics / IPA 2007 Dec;19(6):1110-24
-
Orbitofrontal cortex volume in late life depression: influence of hyperintense lesions and genetic polymorphisms.
Psychological medicine 2007 Dec;37(12):1763-73
-
Review of evidence for genetic testing for CYP450 polymorphisms in management of patients with nonpsychotic depression with selective serotonin reuptake inhibitors.
Genetics in medicine : official journal of the American College of Medical Genetics 2007 Dec;9(12):826-35
-
Allelic differences in the brain-derived neurotrophic factor Val66Met polymorphism in late-life depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2007 Oct;15(10):850-7
-
Fatigue as a core symptom in major depressive disorder: overview and the role of bupropion.
Expert review of neurotherapeutics 2007 Oct;7(10):1251-63
-
Longitudinal magnetic resonance imaging vascular changes, apolipoprotein E genotype, and development of dementia in the neurocognitive outcomes of depression in the elderly study.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2007 Oct;15(10):839-49
-
Prefrontal white matter lesions and prefrontal task impersistence in depressed and nondepressed elders.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007 Oct;32(10):2135-42
-
Association of AGTR1 with 18-month treatment outcome in late-life depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2007 Jul;15(7):564-72
-
How asymptomatic is asymptomatic carotid stenosis?
Radiology 2007 Jul;244(1):317-8, author reply 318-9
-
Job demands and dementia risk among male twin pairs.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2007 Jul;3(3):192-9
-
Spiritual considerations in suicide and depression among the elderly.
Southern medical journal 2007 Jul;100(7):748-9
-
Widespread effects of hyperintense lesions on cerebral white matter structure.
AJR. American journal of roentgenology 2007 Jun;188(6):1695-704
-
Depressive symptoms and age-related macular degeneration in older people: the cardiovascular health study.
Ophthalmic epidemiology 2007 May;14(3):127-33
-
A preliminary metabolomic analysis of older adults with and without depression.
International journal of geriatric psychiatry 2007 May;22(5):418-23
-
Contribution of depression to cognitive impairment and dementia in older adults.
The neurologist 2007 May;13(3):105-17
-
Are microvascular abnormalities in the retina associated with depression symptoms? The Cardiovascular Health Study.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2007 Apr;15(4):335-43
-
Food group intake and brain lesions in late-life vascular depression.
International psychogeriatrics / IPA 2007 Apr;19(2):295-305
-
Persistent mild cognitive impairment in geriatric depression.
International psychogeriatrics / IPA 2007 Feb;19(1):125-35
-
Coenzyme Q10: a review of its promise as a neuroprotectant.
CNS spectrums 2007 Jan;12(1):62-8
-
Prevalence of dementia in the United States: the aging, demographics, and memory study.
Neuroepidemiology 2007 Jan;29(1-2):125-32
-
Satisfaction and outcomes of depressed older adults with psychiatric clinical nurse specialists in primary care.
Journal of the American Nurses Association. 2007 Jan;1362-70
-
Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs).
Evidence report/technology assessment 2007 Jan;(146):1-77
-
Dorsolateral prefrontal cortex and anterior cingulate cortex white matter alterations in late-life depression.
Biological psychiatry 2006 Dec;60(12):1356-63
-
Psychiatric disease in the twenty-first century: The case for subcortical ischemic depression.
Biological psychiatry 2006 Dec;60(12):1299-303
-
The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease.
Biological psychiatry 2006 Dec;60(12):1287-94
-
Duke Twins Study of Memory in Aging in the NAS-NRC Twin Registry.
Twin research and human genetics : the official journal of the International Society for Twin Studies 2006 Dec;9(6):950-7
-
White matter lesion volumes and caudate volumes in late-life depression.
International journal of geriatric psychiatry 2006 Dec;21(12):1193-8
-
Vascular risk factors and cognitive decline among elderly male twins.
Neurology 2006 Nov;67(9):1586-91
-
An introductory clinical core course in psychiatric management: an innovative lifespan course blending all nurse practitioner majors.
Perspectives in psychiatric care 2006 Nov;42(4):245-51
-
Differences in brain volumes among males and female hormone-therapy users and nonusers.
Psychiatry research 2006 Oct;147(2-3):127-34
-
Reducing suicidal ideation in depressed older primary care patients.
Journal of the American Geriatrics Society 2006 Oct;54(10):1550-6
-
Risk factors for neuropsychiatric symptoms in dementia: the Cache County Study.
International journal of geriatric psychiatry 2006 Sep;21(9):824-30
-
Vascular nutritional correlates of late-life depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2006 Sep;14(9):787-95
-
White matter and subcortical gray matter lesion volume changes and late-life depression outcome: a 4-year magnetic resonance imaging study.
International psychogeriatrics / IPA 2006 Sep;18(3):445-56
-
Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed.
Biological psychiatry 2006 Jul;60(1):58-65
-
Lobar distribution of lesion volumes in late-life depression: the Biomedical Informatics Research Network (BIRN).
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006 Jul;31(7):1500-7
-
Cognitive impairment and depression outcomes in the IMPACT study.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2006 May;14(5):401-9
-
Gender differences in the association between religious involvement and depression: the Cache County (Utah) study.
The journals of gerontology. Series B, Psychological sciences and social sciences 2006 May;61(3):P129-36
-
Partial remission. A common outcome in older adults treated for major depression.
Geriatrics 2006 Apr;61(4):22-6
-
Hippocampal volume is associated with physician-reported acute cognitive deficits after electroconvulsive therapy.
Journal of geriatric psychiatry and neurology 2006 Mar;19(1):21-5
-
Three-year incidence of first-onset depressive syndrome in a population sample of older adults: the Cache County study.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2006 Mar;14(3):237-45
-
Depression treatment preferences in older primary care patients.
The Gerontologist 2006 Feb;46(1):14-22
-
Perspectives on depression, mild cognitive impairment, and cognitive decline.
Archives of general psychiatry 2006 Feb;63(2):130-8
-
Ascending digits task as a measure of executive function in geriatric depression.
The Journal of neuropsychiatry and clinical neurosciences 2006 Jan;18(1):117-20
-
Clinical correlates of anxious depression among elderly patients with depression.
Journal of affective disorders 2006 Jan;90(1):37-41
-
Comparison of clinical and neuropathologic diagnoses of Alzheimer's disease in 3 epidemiologic samples.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2006 Jan;2(1):2-11
-
Comparison of clinical and neuropathological diagnoses of AD in three epidemiological samples. Journal of Alzheimer's & Dementia:
The Journal of the Alzheimer's Association 2006 Jan;22-11
-
Residual symptoms in older patients treated for major depression.
International journal of geriatric psychiatry 2005 Dec;20(12):1196-202
-
Prevalence and clinical correlates of neuropsychiatric symptoms in dementia.
American journal of Alzheimer's disease and other dementias 2005 Nov;20(6):367-73
-
Hippocampal volume as a predictor of short-term ECT outcomes in older patients with depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2005 Oct;13(10):910-3
-
Research in geriatric depression: a model for mental health research in the 21st century?
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2005 Oct;13(10):829-33
-
Predictors of partial remission in older patients treated for major depression: the role of comorbid dysthymia.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2005 Aug;13(8):713-21
-
Symptomatic remission in patients with bipolar mania: results from a double-blind, placebo-controlled trial of risperidone monotherapy.
The Journal of clinical psychiatry 2005 Aug;66(8):1016-20
-
Hormone therapy does not affect depression severity in older women.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2005 Jul;13(7):616-23
-
Greater MRI lesion volumes in elderly depressed subjects than in control subjects.
Psychiatry research 2005 May;139(1):1-7
-
Influence of serotonin transporter promoter region polymorphisms on hippocampal volumes in late-life depression.
Archives of general psychiatry 2005 May;62(5):537-44
-
Biological and social predictors of long-term geriatric depression outcome.
International psychogeriatrics / IPA 2005 Mar;17(1):41-56
-
Social support and locus of control as predictors of adherence to antidepressant medication in an elderly population.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2005 Feb;13(2):157-65
-
Impact of symptoms of generalized anxiety disorder on the course of late-life depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2005 Jan;13(1):40-7
-
The Aging, Demographics, and Memory Study: study design and methods.
Neuroepidemiology 2005 Jan;25(4):181-91
-
Age effects of coronary artery bypass graft on cognitive status change among elderly male twins.
Neurology 2004 Dec;63(12):2245-9
-
Is there a definition of remission in late-life depression that predicts later relapse?
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004 Dec;29(12):2272-7
-
Methodology and preliminary results from the neurocognitive outcomes of depression in the elderly study.
Journal of geriatric psychiatry and neurology 2004 Dec;17(4):202-11
-
Prefrontal neuropsychological predictors of treatment remission in late-life depression.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004 Dec;29(12):2266-71
-
Establishing diagnostic criteria for vascular depression.
Journal of the neurological sciences 2004 Nov;226(1-2):59-62
-
Statin use and hippocampal volumes in elderly subjects at risk for Alzheimer's disease: a pilot observational study.
American journal of Alzheimer's disease and other dementias 2004 Sep;19(5):275-8
-
Late-life depression and microstructural abnormalities in dorsolateral prefrontal cortex white matter.
The American journal of psychiatry 2004 Jul;161(7):1293-6
-
Clinical characteristics of magnetic resonance imaging-defined subcortical ischemic depression.
Biological psychiatry 2004 Feb;55(4):390-7
-
Evaluation and treatment of depression in patients with cognitive impairment.
Clinical Geriatrics 2004 Jan;1239-47
-
The persistence of neuropsychiatric symptoms in dementia: the Cache County Study.
International journal of geriatric psychiatry 2004 Jan;19(1):19-26
-
Left orbital frontal cortex volume and performance on the benton visual retention test in older depressives and controls.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003 Dec;28(12):2179-83
-
The association of psychosocial factors and depression with hypertension among older adults.
International journal of geriatric psychiatry 2003 Dec;18(12):1142-8
-
MRI lesion severity and mortality in geriatric depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2003 Nov;11(6):678-82
-
White matter hyperintensity progression and late-life depression outcomes.
Archives of general psychiatry 2003 Nov;60(11):1090-6
-
Apolipoprotein E genotype and subcortical vascular lesions in older depressed patients and control subjects.
Biological psychiatry 2003 Oct;54(7):674-81
-
Progression of subcortical ischemic disease from vascular depression to vascular dementia.
The American journal of psychiatry 2003 Oct;160(10):1751-6
-
The impact of religious practice and religious coping on geriatric depression.
International journal of geriatric psychiatry 2003 Oct;18(10):905-14
-
Subcortical lesion severity and orbitofrontal cortex volume in geriatric depression.
Biological psychiatry 2003 Sep;54(5):529-33
-
Serial MR imaging of volumes of hyperintense white matter lesions in elderly patients: correlation with vascular risk factors.
AJR. American journal of roentgenology 2003 Aug;181(2):571-6
-
Implementing a disease management intervention for depression in primary care: a random work sampling study.
General hospital psychiatry 2003 Jul;25(4):238-45
-
Partial response as a predictor of outcome in geriatric depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2003 May;11(3):340-8
-
Localization of age-associated white matter hyperintensities in late-life depression.
Progress in neuro-psychopharmacology & biological psychiatry 2003 May;27(3):539-44
-
Apolipoprotein E genotype and major depression in a community of older adults. The Cache County Study.
Psychological medicine 2003 Apr;33(3):541-7
-
Associations among the NEO Personality Inventory, Revised and the serotonin transporter gene-linked polymorphic region in elders: effects of depression and gender.
Psychiatric genetics 2003 Mar;13(1):13-8
-
Smaller orbital frontal cortex volumes associated with functional disability in depressed elders.
Biological psychiatry 2003 Jan;53(2):144-9
-
A three-factor analytic model of the MADRS in geriatric depression.
International journal of geriatric psychiatry 2003 Jan;18(1):73-7
-
Cholesterol-lowering medication and relapse of depression.
Psychopharmacology bulletin 2003 Jan;37(4):92-8
-
Geriatrics.
Gen Hosp Psychiatry, Consultation-Liaison Psychiatry Database (2003 Update and National Lists). Part II: Topics, Contributors, and Database. 2003 Jan;25422-425
-
The incidence of mental and behavioral disturbances in dementia: the cache county study.
The Journal of neuropsychiatry and clinical neurosciences 2003 Jan;15(3):340-5
-
Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study.
JAMA 2002 Nov;288(17):2123-9
-
Greater depression severity associated with less improvement in depression-associated cognitive deficits in older subjects.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2002 Sep;10(5):632-5
-
Sociodemographic and clinical predictors of mortality in geriatric depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2002 Sep;10(5):531-40
-
Time-to-remission from geriatric depression: psychosocial and clinical factors.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2002 Sep;10(5):551-9
-
Investigation of Notch3 as a candidate gene for bipolar disorder using brain hyperintensities as an endophenotype.
American journal of medical genetics 2002 Aug;114(6):652-8
-
Anatomic location and laterality of MRI signal hyperintensities in late-life depression.
Journal of psychosomatic research 2002 Aug;53(2):665-76
-
Behavioral medicine and aging.
Journal of consulting and clinical psychology 2002 Jun;70(3):843-51
-
Cerebrovascular disease and evolution of depressive symptoms in the cardiovascular health study.
Stroke; a journal of cerebral circulation 2002 Jun;33(6):1636-44
-
Hippocampal volume and antidepressant response in geriatric depression.
International journal of geriatric psychiatry 2002 Jun;17(6):519-25
-
Allelic differences in the serotonin transporter-linked polymorphic region in geriatric depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2002 Mar;10(2):185-91
-
Provisional diagnostic criteria for depression of Alzheimer disease.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2002 Mar;10(2):125-8
-
APOE genotype and hippocampal volume change in geriatric depression.
Biological psychiatry 2002 Mar;51(5):426-9
-
Psychosocial and clinical predictors of unipolar depression outcome in older adults.
International journal of geriatric psychiatry 2002 Mar;17(3):238-46
-
Hippocampal volume and incident dementia in geriatric depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2002 Jan;10(1):62-71
-
Head injury in early adulthood and the lifetime risk of depression.
Archives of general psychiatry 2002 Jan;59(1):17-22
-
Subcortical white matter lesions and functional impairment in geriatric depression.
Depression and anxiety 2002 Jan;15(1):23-8
-
The Duke Somatic Treatment Algorithm for Geriatric Depression (STAGED) approach.
Psychopharmacology bulletin 2002 Jan;36(2):58-68
-
Hormone replacement therapy and reduced cognitive decline in older women: the Cache County Study.
Neurology 2001 Dec;57(12):2210-6
-
Does social support buffer functional decline in elderly patients with unipolar depression?
The American journal of psychiatry 2001 Nov;158(11):1850-5
-
Neuropsychiatric disturbance in Alzheimer's disease clusters into three groups: the Cache County study.
International journal of geriatric psychiatry 2001 Nov;16(11):1043-53
-
Bupropion SR in the naturalistic treatment of elderly patients with major depression.
International journal of geriatric psychiatry 2001 Sep;16(9):862-5
-
Performance feedback deficit in geriatric depression.
Biological psychiatry 2001 Sep;50(5):358-63
-
MRI correlates of suicide attempt history in unipolar depression.
Biological psychiatry 2001 Aug;50(4):266-70
-
Evidence of white matter tract disruption in MRI hyperintensities.
Biological psychiatry 2001 Aug;50(3):179-83
-
Depressive symptoms, menopausal status, and climacteric symptoms in women at midlife.
Psychosomatic medicine 2001 Jul;63(4):603-8
-
Severity of subcortical gray matter hyperintensity predicts ECT response in geriatric depression.
The journal of ECT 2001 Mar;17(1):45-9
-
Diagnosis, epidemiology, and clinical course of geriatric depression.
TEN: Trends in Evidence-Based Neuropsychiatry 2001 Jan;340-43
-
Relation of subjective and received social support to clinical and self-report assessments of depressive symptoms in an elderly population.
Journal of affective disorders 2000 Dec;61(1-2):41-50
-
Reduction of orbital frontal cortex volume in geriatric depression.
Biological psychiatry 2000 Nov;48(10):971-5
-
Grey-matter lesions and dementia.
Lancet (London, England) 2000 Nov;356(9242):1686-7
-
Documented head injury in early adulthood and risk of Alzheimer's disease and other dementias.
Neurology 2000 Oct;55(8):1158-66
-
Hippocampal volume in geriatric depression.
Biological psychiatry 2000 Aug;48(4):301-9
-
Driving cessation in older men with incident dementia.
Journal of the American Geriatrics Society 2000 Aug;48(8):928-30
-
Prevalence of depression and its treatment in an elderly population: the Cache County study.
Archives of general psychiatry 2000 Jun;57(6):601-7
-
Mental and behavioral disturbances in dementia: findings from the Cache County Study on Memory in Aging.
The American journal of psychiatry 2000 May;157(5):708-14
-
APOE and AD concordance in twin pairs as predictors of AD in first-degree relatives.
Neurology 2000 Feb;54(3):593-8
-
The relationship of social support, social networks and negative events with depression in patients with coronary artery disease.
Aging and Mental Health 2000 Jan;4253-258
-
Initial evaluation of suspected dementia. Asking the right questions.
Postgraduate medicine 1999 Oct;106(5):72-6, 79-80, 82-3
-
Cerebrovascular disease and depression symptoms in the cardiovascular health study.
Stroke; a journal of cerebral circulation 1999 Oct;30(10):2159-66
-
Enhanced cognitive performance with estrogen use in nondemented community-dwelling older women.
Journal of the American Geriatrics Society 1999 Oct;47(10):1171-5
-
APOE-epsilon4 count predicts age when prevalence of AD increases, then declines: the Cache County Study.
Neurology 1999 Jul;53(2):321-31
-
The effect of major depression on functional status in patients with coronary artery disease.
Journal of the American Geriatrics Society 1999 Mar;47(3):319-22
-
Decision analysis of long versus short half-life SSRIs.
Primary Psychiatry 1999 Jan;655-58
-
Disability in geriatric depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 1999 Jan;7(1):34-40
-
Geriatric depression: further evidence for the ‘vascular depression’ hypothesis.
Current Opinion in Psychiatry 1999 Jan;12463-470
-
Geriatrics.
In Strain JJ (ed.) Consultation-Liaison Psychiatry Database (2000 Update). Part III: Topics, Contributors, and Database. Gen Hosp Psychiatry 1999 Jan;21466-468
-
Familial leukoencephalopathy in bipolar disorder.
The American journal of psychiatry 1998 Nov;155(11):1605-7
-
Combination therapy for early Alzheimer's disease: what are we waiting for?
Journal of the American Geriatrics Society 1998 Oct;46(10):1322-4
-
Magnetic resonance imaging signal hypointensity and iron content of putamen nuclei in elderly depressed patients.
Psychiatry research 1998 Aug;83(2):95-103
-
APOE genotype predicts when--not whether--one is predisposed to develop Alzheimer disease.
Nature genetics 1998 Aug;19(4):321-2
-
Structural neuroimaging and mood disorders: recent findings, implications for classification, and future directions.
Biological psychiatry 1998 May;43(10):705-12
-
The use of flumazenil in the anxious and benzodiazepine-dependent ECT patient.
The journal of ECT 1998 Mar;14(1):5-14
-
Psychotherapeutic agents in older adults. Metabolism, bioavailability, and drug interactions.
Clinics in geriatric medicine 1998 Feb;14(1):17-31
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Early recognition of Alzheimer's disease: what is consensual? What is controversial? What is practical?
The Journal of clinical psychiatry 1998 Jan;59 Suppl 136-18
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Metabolism, bioavailability and drug-drug interactions.
Clin Geriatr Med 1998 Jan;1417-31
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Using a decision model to compare SSRIs and TCAs.
Primary Psychiatry 1998 Jan;579-84
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A review of racial differences in geriatric depression: implications for care and clinical research.
Journal of the National Medical Association 1997 Nov;89(11):731-6
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A twin study of late-onset depression and apolipoprotein E epsilon 4 as risk factors for Alzheimer's disease.
Biological psychiatry 1997 Apr;41(8):851-6
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Are SSRIs better than TCAs? Comparison of SSRIs and TCAs: a meta-analysis.
Depression and anxiety 1997 Jan;6(1):10-8
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Psychotropic drug interactions.
Primary Psychiatry 1997 Jan;424-53
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When to make an adult psychiatric referral.
Primary Psychiatry 1997 Jan;4(12):18-40
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Magnetic resonance imaging changes in putamen nuclei iron content and distribution in normal subjects.
Psychiatry research 1996 Nov;68(1):55-61
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Sociodemographic and clinical correlates of number of previous depressive episodes in the depressed elderly.
Journal of affective disorders 1996 Jul;39(2):99-106
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Decision model for the acute treatment of mania.
Depression and anxiety 1996 Jan;4(6):289-93
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Insomnia: A Practical Review.
Medical Update for Psychiatrists 1996 Jan;1(6):183-187
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Cost effectiveness of maintenance ECT.
Convulsive therapy 1995 Dec;11(4):283-4
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Alzheimer's disease in the National Academy of Sciences-National Research Council Registry of Aging Twin Veterans. III. Detection of cases, longitudinal results, and observations on twin concordance.
Archives of neurology 1995 Aug;52(8):763-71
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Carbon monoxide-related organic mood disorder successfully treated with ECT.
The Journal of clinical psychiatry 1995 Jul;56(7):332-3
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The neurostructural/neurofunctional basis of
depression/mania.
Current Opinion in Psychiatry 1993 Jan;622-26
Abstracts
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Cerebral-cerebellar connectivity in prediction of cognitive decline in late-life depression.
Annual Conference of American Association of Geriatric Psychiatry 2013 Mar;
Editorials
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Late-Life Depression, Antidepressant Treatment, and Cognition: The Short Haul and the Long Haul.
The American journal of psychiatry 2024 Mar;181(3):183-185
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Cerebrovascular Disease and Neuropsychiatric Disorders: Translating Findings From the MRI Scanner to the Clinic.
The American journal of psychiatry 2023 Jul;180(7):467-469
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Applying the construct of social determinants of health to imaging-based brain changes.
International psychogeriatrics 2023 Apr;1-9
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Risk Prediction in Late Life Depression: A Screening Tool, a Teaching Tool.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2022 Sep;30(9):961-963
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Can Addressing Personality Change Enhance Cognitive Functioning and Delay Development of Mild Cognitive Impairment?
Journal of the American Geriatrics Society 2018 Jan;66650-651
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Editorial Comment: Is It Time to Take the "Sub" Out of Subsyndromal Depression?
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2017 Sep;25(9):992-993
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Vascular depression consensus report - a critical update.
BMC medicine 2016 Nov;14(1):161
Reviews
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Treatment-Resistant Depression in Older Adults.
The New England journal of medicine 2024 Feb;390(7):630-639
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The neurobiology of apathy in depression and neurocognitive impairment in older adults: a review of epidemiological, clinical, neuropsychological and biological research.
Translational psychiatry 2022 Dec;12(1):525
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Sleep Disturbances in the Elderly.
The Psychiatric clinics of North America 2015 Dec;38(4):723-41
Title or Abstract | Type | Sponsor/Event | Date/Year | Location |
---|---|---|---|---|
"Effects of Longitudinal Changes in Neuroticism and Stress on Cognitive Decline” | Talk | Journal Club, American Association for Geriatric Psychiatry | 2023 | Virtual |
"Linking late-life depression, cognitive impairment, and dementia.” Psychiatry Grand Rounds, February 11, 2020 | Lecture | Stony Brook University Department of Psychiatry | 2020 | Stony Brook University |