Photo of Mahesh Thirunavukkarasu, Ph.D.

Mahesh Thirunavukkarasu, Ph.D.

Assistant Professor of Surgery
Academic Office Location:
Department of Surgery
UConn Health
263 Farmington Avenue
Farmington, CT 06030
Phone: 860-679-8089
860-679-2825
Fax: 860-679-2825
Education
DegreeInstitutionMajor
B.Sc.University of MadrasBiochemistry
M.Sc.Annamalai University, Annamalai NagarBiochemistry
M.Phil.Annamalai University, Annamalai NagarBiochemistry
Ph.D.Annamalai University, Annamalai Nagar,Biochemistry

Post-Graduate Training
TrainingInstitutionSpecialty
PostdoctoralUniversity of Connecticut Health CenterUniversity Postdoctoral Fellow

Awards
Name of Award/HonorAwarding Organization
Dr. Reddy’s Laboratories Junior Scientist Award in Molecular BiologyASIOA
Resident/Fellow Excellence in Research Award: Cardiothoracic surgeryAmerican College of Surgeons
Resident/Fellow Excellence in Research Award: Cardiothoracic SurgeryAmerican College of Surgeons
Resident/Fellow Excellence in Research Award: Vascular SurgeryAmerican College of Surgeons
BCVS Abstract Travel GrantAmerican Heart Association
Young Investigator AwardInternational College of Angiology
Name & DescriptionCategoryRoleTypeScopeStart YearEnd Year
AHA Pre and Post-doctoral Fellowship, Cardiology 2 Fellowship committee, Cardiac Biology Basic Science as the primary science classificationStudy SectionReviewerExternalNational20212023
Molecular Biology ReportsEditorial BoardEditorial Board MemberExternalInternational2014
Guest editor for the special issue “Antioxidants in Longevity and Medicine” in the journal Oxidative Medicine and LongevityEditorial BoardGuest EditorExternalInternational20142014
Guest Editor for the special Issue “Antioxidants in Longevity and Medicine” in the journal Oxidative Medicine and LongevityEditorial BoardGuest EditorExternalInternational20132013
American Heart AssociationProfessional/Scientific OrganizationMemberExternalNational

Journal Articles

Book Chapters

  • Personalized Nutrition The New Era of Nutrition/ Chapter 2
    Diego Accorsi, Pradeep Seetur Radhakrishna, Jennifer Hubbard, Rajesh Lakshmanan, Nilanjana Maulik, and Mahesh Thirunavukkarasu. Personalized Nutrition as Medical Therapy for High-Risk Diseases 2020 Apr;
  • The effects of resveratrol on Diabetes and obesity, Chapter 33
    Sanchez JA, Thirunavukkarasu M and Maulik N. Nutritional and Therapeutic Intervention of Diabetes and Metabolic Syndrome 2011 Jan;413-430

Abstracts

  • Cardiomyocyte Specific Overexpression of Pellino-1 Reverses Sepsis induced Cardiac Dysfunction in a Murine Model by Reducing Inflammatory Response and Cardiac Cell Death
    Santosh Swaminathan, Seetur Radhakrishna Pradeep, Rickesha L. Wilson, Jacob Campbell, Mahesh Thirunavukkarasu, Diego Accorsi, Alexander J Palesty, Nilanjana Maulik. Circulation 2020 Nov;142(Suppl No.3):A14673
  • Cardiomyocyte Specific Pellino1 Knockout Leads to Increased Oxidative Stress, Reduced Anti-apoptotic Signaling and Cardiac Dysfunction in a Murine Myocardial Infarction Model.
    Seetur R. Pradeep, Jacob campbell, Mahesh THIRUNAVUKKARASU, Diego Accorsi, J. Alexander Palesty, Nilanjana Maulik Circulation 2020 Nov;142(Suppl No. 3):A15238
  • Gene Therapy with Pellino-1 Improves Perfusion and Decreases Tissue Loss in an Flk-1 Heterozygous Murine Hind Limb Ischemia Model But Fails In MAPKAPKinase2 Knockout Mice
    Diego Accorsi, Mahesh Thirunavukkarasu, Gopi Ukani, Mark Youssef, Santosh Swaminathan, Alexander Palesty, Nilanjana Maulik. Circulation 2020 Nov;142(Suppl No.3):A15314
  • Pellino-1 overexpression in cardiomyocyte enhances cardiac function and attenuates ventricular remodeling in murine myocardial infarction model.
    Jacob Campbell, Vaithinathan Selvaraju, Mahesh Thirunavukkarasu,Coca-Soliz Vladamir, Leonidias Tapias, Kurapaty Venkatapoorna Chandramohan, Siu-Pok Yee, David W McFadden, J.Alexander Palesty, Maulik N. Journal of the American College of Surgeons 2017 Oct;225S33

Editorials

Letters

Other

  • Andrew Kemerley Clinical Congress 2022, American College of Surgeons: Owen H Wangensteen Scientific Forum Excellence in Research Awards, Journal of the American College of Surgeons 2022 Nov;235(5)S5-S16

Reviews

Title or AbstractTypeSponsor/EventDate/YearLocation
Isolation and Characterization of Thioredoxin-1 Engineered Exosomes and its Role in Cardiac Function Following Myocardial InfarctionTalkNESS, 26th Annual Surgical Resident and Fellow Presentation Day2019Waltham, MA
Injection of Exosomes Isolated from Thioredoxin-1 Overexpressed Mice Leads to Improved Cardiac Function and Decreased Fibrosis after Myocardial Infarction.TalkClinical Congress, Americal college of Surgeons2019San Francisco
Resveratrol-Loaded PCL Scaffold Improves Cardiac Function after Myocardial Infarction in MicePosterClinical Congress, Americal college of Surgeons2019San Francisco
Bioengineered Nanofiber Scaffold Induces Healthy Wound Healing in a Murine Ischemic Full-thickness wound modelPosterAnnual Biomedical Research Conference for Minority Students (ABRCMC)2019Anaheim, California
Jacob D. Campbell, Vaithinathan Selvaraju, Rajesh Lakshmanan, Mahesh Thirunavukkarasu, David W. McFadden, Nilanjana Maulik. Bioengineered Nanofiber Scaffold Loaded with Resveratrol Improves Cardiac Function Following Myocardial Infarction After Four Weeks.TalkNESS, 25th Annual Surgical Resident and Fellow Presentation Day2018Waltham, MA
Gopi D. Ukani1, Jacob Campbell, Rajesh Lakhsmanan, André O’Reilly Beringhs, Vaithinathan Selvaraju, Mahesh Thirunavukkarasu, Virginia Parker, Xiuling Lu, J Alexander Palesty, Nilanjana Maulik. Utilization of a Novel Engineered Nanofibrous Scaffold Loaded with Resveratrol in a Preclinical Full Thickness Wound Model in Mice.TalkNESS, 25th Annual Surgical Resident and Fellow Presentation Day2018Waltham, MA
Campbell JD, Selvaraju V, Thirunavukkarasu M, Coca-Soliz V, Tapias L, Kurapaty Venkatapurana CM, Yee S, McFadden DW, Palesty JA, Maulik N. Pellion-1 overexpression in cardiomyocyte enhances cardiac function and attenuates ventricular remodeling in murine myocardial infarction model.TalkAmerican College of Surgeons -2017 Clinical Congress2017San Diego, CA
Campbell JD, Selvaraju V, Lakshmanan R, Thirunavukkarasu M, McFadden DW, Maulik N. Bioengineered nanofiber scaffold loaded with resveratrol improves cardiac function following myocardial infarction: our preliminary findings.TalkConnecticut Chapter of the American College of Surgeons2017Connecticut