Photo of Oscar  Vargas-Rodriguez, Ph.D.

Oscar Vargas-Rodriguez, Ph.D.

Assistant Professor, Department of Molecular Biology and Biophysics
Academic Office Location:
Molecular Biology & Biophysics
UConn Health
263 Farmington Avenue
Farmington, CT 06030-3305
Phone: 860-679-8484

Lab Website

Molecular Biology and Biochemistry Graduate Program

B.S.Pontifical Catholic University of Puerto RicoChemistry
Ph.D.The Ohio State UniversityBiological Chemistry

Post-Graduate Training
PostdoctoralYale UniversityDepartment of Molecular Biophysics & Biochemistry

We are a bacteriology lab studying the molecular bases that enable pathogenic bacteria to endure, acclimate, and prevail in the unwelcoming conditions of their host. Our research seeks to understand how bacterial pathogens regulate protein synthesis (translation) in response to interactions with their host, especially during colonization and infection.

Our research focuses on the function of a family of translation factors known as aminoacyl-tRNA synthetases (aaRS). These enzymes are indispensable for life as they are responsible for the accurate and efficient translation of the genetic code during gene expression. We aim to understand the biological role of aaRSs during host-pathogen interactions as potential virulence factors and druggable targets using a combination of biochemical, biophysical, molecular, cellular, multi-omics, and computational approaches.

In addition to our commitment to rigorous and innovative research, we strive to create a collegial and inclusive environment wherein our team trainees are supported and empowered to accomplish their career goals.

We are accepting Lab Rotation Students: Spring and Summer 2023.

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